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USMLE STEP 2 Fourth Edition Theodore X. O’Connell, MD Program Director, Family Medicine Residency Program Kaiser Permanente Napa-Solano, California Assistant Clinical Professor, Department of Community and Family Medicine University of California, San Francisco School of Medicine, San Francisco, California Assistant Clinical Professor, Department of Family Medicine David Geffen School of Medicine at UCLA Los Angeles, California 1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103-2899 USMLE STEP 2 SECRETS, FOURTH EDITION ISBN: 978-0-323-18814-2 Copyright © 2014, 2010, 2004 by Saunders, an imprint of Elsevier Inc. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Library of Congress Cataloging-in-Publication Data O’Connell, Theodore X., author USMLE step 2 secrets : questions you will be asked / Theodore X. O’Connell. -- Fourth edition. p. ; cm. -- (Secrets series) Preceded by USMLE step 2 secrets / Theodore X. O’Connell, Adam Brochert. 3rd edition. 2010. Includes bibliographical references and index. ISBN 978-0-323-18814-2 (alk. paper) I. Title. II. Series: Secrets series. [DNLM: 1. Clinical Medicine--Examination Questions. WB 18.2] RC58 616.0076--dc23 2013021243 Senior Content Strategist: Jim Merritt Content Development Specialist: Julia Roberts Publishing Services Manager: Anne Altepeter Project Manager: Ted Rodgers Designer: Steven Stave Printed in the United States of America Last digit is the print number: 9 8 7 6 5 4 3 2 1 To Nichole, Ryan, Sean, and Claire. I love you. Plate 1. Infant with fetal alcohol syndrome. Note short palpebral fissures, mild ptosis, nostrils, smooth philtrum, and narrow vermillion of the upper lip. See Figure 2-1, p. 26. (From Gilbert-Barness E. Potter’s pathology of the fetus, infant, and child, 2nd ed. Philadelphia: Elsevier, 2007, Fig. 4.1.12.) Plate 2. Xanthelasma. Multiple soft, yellow plaques involving the lower eyelid. Xanthelasma is usually a normal finding with no significance but is classically seen on the USMLE because of its association with hypercholesterolemia. Screen affected patients with a fasting lipid profile. See Figure 5-1, p. 52. (From Yanoff M, Duker JS. Ophthalmology, 3rd ed. Philadelphia: Mosby, 2008, Fig. 12-9-18.) Plate 3. Allergic contact dermatitis of the leg caused by an elastic wrap. Notice the well-marginated distribution that differentiates it from cellulitis. See Figure 6-1, p. 55. (From Auerbach PS. Wilderness medicine, 6th ed. Philadelphia: Mosby, 2011.) Plate 4. Tinea corporis. Red ring-shaped lesions with scaling and some central clearing. See Figure 6-2, p. 56. (From K liegman RM. Nelson textbook of pediatrics, 19th ed. Philadelphia: Saunders, 2011.) Plate 5. Pityriasis rosea. Small oval plaques as well as multiple small papules are present. See Figure 6-3, p. 59. (From Habif TP. Clinical dermatology, 5th ed. St. Louis: Mosby, 2009.) Plate 6. Lichen planus. Flat-topped, purple polygonal papules of lichen planus. See Figure 6-4, p. 60. (From Kliegman RM. Nelson textbook of pediatrics, 19th ed. Philadelphia: Saunders, 2011.) Plate 7. Erythema multiforme. “Bull’s-eye” annular lesions with central vesicles and bullae. See Figure 6-5, p. 60. (From Goldman L. Goldman’s Cecil medicine, 24th ed. Philadelphia: Saunders, 2011.) Plate 8. Erythema nodosum on the legs of a young woman. See Figure 6-6, p. 61. (From Hochberg MC. Rheumatology, 5th ed. Philadelphia: Mosby, 2010.) Plate 9. Bullous pemphigoid. Tense subepidermal bullae on an erythematous base. See Figure 6-7, p. 61. (From Goldman L. Goldman’s Cecil medicine, 24th ed. Philadelphia: Saunders, 2011.) Plate 10. Dermatitis herpetiformis is characterized by pruritus, urticarial papules, and small vesicles. See Figure 6-8, p. 62. (From Feldman M. Sleisenger and Fordtran’s gastrointestinal and liver disease, 9th ed. Philadelphia: Saunders, 2010; Courtesy Dr. Timothy Berger, San Francisco, Calif.) Plate 11. Melanoma (superficial spreading type). See Figure 6-9, p. 63. (From Goldman L. Goldman’s Cecil medicine, 24th ed. Philadelphia: Saunders, 2011.) Plate 12. Keratoacanthoma on the right upper lid. Lesions are solitary, smooth, dome-shaped red papules or nod- ules with a central keratin plug. See Figure 6-10, p. 64. (From Albert DM. Albert & Jakobiec’s principles and practice of ophthalmology, 3rd ed. Philadelphia: Saunders, 2008.) Plate 13. Keloid of the earlobe after piercing. See Figure 6-11, p. 64. (From Kliegman RM, Stanton BF, St. Geme JW III, et al. Nelson textbook of pediatrics, 19th ed. Philadelphia: Saunders, 2011.) Plate 14. An ulcerated basal cell carcinoma with rolled borders on the posterior ear. See Figure 6-12, p. 65. (From Abeloff DA, Armitage JO, Niederhuber JE, et al. Abeloff’s clinical oncology, 4th ed. Philadelphia: Churchill Livingstone, 2008.) Plate 15. Squamous cell carcinoma on the lower lip. See Figure 6-13, p. 65. (From Rakel RE, Rakel DP. Textbook of family medicine, 8th ed. Philadelphia: Saunders, 2011. © Richard P. Usatine.) Plate 16. Multiple actinic keratoses visible as thin, red, scaly lesions. See Figure 6-14, p. 66. (From Goldberg DJ. Procedures in cosmetic dermatology: lasers and lights, Vol 1, 2nd ed. Saunders, 2008.) Plate 17. Nailbed melanoma. See Figure 6-15, p. 67. (From Goldman L, Schafer AI. Goldman’s Cecil medicine, 24th ed. Philadelphia: Saunders, 2011.)

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