Table Of Content

TRENDS IN REFERENCE EDITION BIOTECHNOLOGY Volume 9 1991 CONTENTS JANUARY Workshop Protein fusions: bioseparation and application, by R. Sherwood Biotopics New attempts to solve protein structures lead to MADness, by Michael] . Geisow The proof of the cloning is in the eating, by MichaelJ .G eisow Feature Progress towards rabies control, by Morag Ferguson Reviews Extending the chemistry of enzymes and abzymes, by Donald Hilvert Towards an understanding of the genetics of bacterial metal resistance, by Max Mergeay Gene transfer via somatic hybridization in plants, by Kristina GlimeliusJ,a n Fahlesson, Maria Landgren, Christina Sjodin and Eva Sundberg Transposons as tools for the isolation of plant genes, by Lluis Balcells, June Swinburne and George Coupland Book Reviews Biotechnology: Microbes and the Environment (by Steven C. Witt), by W. Allan Hamilton Biotechnology of Plant—Microbe Interactions (edited by J. P. Nakas and C. Hagedorn), by Charles H. Shaw FEBRUARY Workshop Catalytic antibodies — something for everyone, by T.J . R. Harris Undercurrents Reconstituted viral envelopes — ‘Trojan Horses’ for drug delivery and gene therapy? by Robert Blumenthal and Abraham Loyter Biotopics Do-it-yourself molecules: chaperonin self-assembly, by MichaelJ .G eisow The twists and turns of biopolymer migration, by MichaelJ . Geisow Back from the future? by MichaelJ .G eisow Reviews Cystic fibrosis — the way forward from the gene, by Julia R. Dorin and DavidJ . Porteous Exponential amplification of nucleic acids: new diagnostics using DNA polymerases and RNA replicases, by Paul M. Lizardi and Fred Russell Kramer Repacking protein interiors, by Warren S. Sandberg and Thomas C. Terwilliger Mycelial morphology and metabolite production, by Sergei Braun and Susan E. Vecht-Lifshitz Book Reviews Guide to Protein Purification: Methods in Enzymology Vol. 182 (edited by Murray P. Deutscher), by MichaelJ .G eisow Protein Purification — Principles, High Resolution Methods and Applications (edited by Jan-Christer Janson and Lars Ryden), by Roy Harris Biotechnology: A Laboratory Course (by J. M. Becker, G. A. Caldwell and E. A. Lachgo), by Kate Graeme-Cook MARCH Workshop Intracellular immunization: a new strategy for producing disease-resistant transgenic livestock? by Peter Staeheli Capturing the light and capturing the market, by Clare Robinson Biotopics Public funding of research and development: a broad picture, by MichaelJ .G eisow Anti-angiogenesis: towards a molecular tourniquet, by MichaelJ . Geisow Nitrogen-fixation in plants: can Rhizobium live with non-legume crops? by John A. Bryant Feature The competitive market for antiplatelets and thrombolytics: can a new entrant succeed? by Lisa Y. Shepard Reviews Redesigning t-PA for improved thrombolytic therapy, by JeffH . Robinson and MichaelJ .B rowne Applications of bacterial magnets, by Tadashi Matsunaga Studying DNA-protein interactions using NMR, by Irina M. Russu Book Reviews Enzymes as Targets for Drug Design (edited by M. G. Palfreyman et a/.), by Dexter B. Northrop The Bacterial Chromosome (edited by Karl Drilca and Monica Riley), by Iain S. Hunter Flow Cytometry — A Practical Approach (edited by M. G. Ormerod), by Tore Lindmo Techniques in HIV Research (edited by Anna Aldovini and Bruce D. Walker), by A. J. Garrett Workshop Antibodies in plants, by William F. Swain 107 Undercurrents Myeloma based expression system for production of large mammalian proteins, by André Traunecker, Filippo Oliveri and Klaus Karjalainen 109 Biotopics Binding contracts: antibody engineering, by MichaelJ .G eisow 113 From sphygmomanometers to synchrotrons: the progress of protein structure determination, by MichaelJ . Geisow 115 Feature Biotechnology and intellectual property; Part 1: Patenting in biotechnology, by R. Stephen Crespi 117 Letter Does co-suppression of sense genes in transgenic plants involve antisense RNA? by Don Grierson, Rupert G. Fray, AndrewJ .H amilton, ChristopherJ . S. Smith and Colin F. Watson 122 Reviews CD4-targeted immune intervention: a strategy for the therapy of AIDS and autoimmune disease, by Charles Auffray, Dominique Piatier- Tonneau and Guido Kroemer 124 Single chain antibody variable regions, by Robert E. Bird and Barbara Webb Walker 132 Understanding bacterial biofilms, by S. A. Blenkinsopp andJ . W. Costerton 138 Book Reviews Optical Microscopy for Biology (edited by Brian Herman and Ken Jacobson), by Chris Hutchison 143 Enzyme Technology (by M. F. Chaplin and C. Bucke), by M. J. C. Crabbe Workshop Designing the optimal oligo, by Craig Binnie 145 Tailoring and targeting fibroblast growth factors, by C. Jane Robinson Biotopics Life support systems for nanotechnology, by Michael] . Geisow 148 Stabilizing protein products: coming in from the cold, by MichaelJ .G eisow Features Biotechnology and intellectual property; Part 2: Microorganism deposit questions and agricultural biotechnology issues, by R. Stephen Crespi Reviews The prospects for therapy with tumour necrosis factors and their antagonists, by Alan G. Porter 158 Predicting antigenic sites on proteins, by Peter S. Stern 163 Human and mouse monoclonal antibodies by repertoire cloning, by Dennis R. Burton Book Reviews Genetic Engineering of Crop Plants (edited by G. W. Lycett and D. Grierson), by John Draper Biofilms (edited by William G. Characklis and Kevin C. Marshall), by Hans-Curt Flemming Workshop Insect control with transgenic plants: resistance proof? by Jeroen Van Rie Biotopics Annexins — forms without function — but not without fun’, by Michael] . Geisow Letters More about co-suppression’, by Jos Mol, Rik van Blokland and Jan Kooter Feature Biotechnology in Japan — towards the year 2000... and beyond, by Alfred Scheidegger Reviews Application of reversibly soluble polymers in bioprocessing, by Michihiro Fujii and Masayuki Taniguchi Insect control with genetically engineered crops, by KarenJ . Brunke and Ronald L. Meeusen Protein adsorption to solid surfaces, by Marie Wahlgren and Thomas Arnebrant Conformational features of signal sequences and folding of secretory proteins in yeasts, by Masakazu Kikuchi and Morio Ikehara Book Reviews Gene Probes for Bacteria (edited by A. J. L. Macario and E. Conway de Macario), by Gordon Dougan Gene Cloning, 2nd edn (by T. A. Brown), by Peter Sudbery Molecular Cloning: A Laboratory Manual, 2nd edn (by J. Sambrook, E. F. Fritsch and T. Maniatis), by Graeme A. Reid Postimplantation Mammalian Embryos — A Practical Approach (edited by A. J. Copp and D. L. Cockroft), by Ian Wilmut DNA Fingerprinting — an Introduction (by Lorne T. Kirby), by Karen M. Sullivan * see Errata JULY Editorial The new T/BTECH: From research to application — the science behind the business, by Clare Robinson Biotopics The evolution of the word ‘Biotechnology’, by MaxJ . Kennedy The coming of age of glycobiology, by MichaelJ .G eisow Focus Multienzyme systems obtained by gene fusion, by Leif Biilow and Klaus Mosbach Reviews Towards third-generation whooping cough vaccines, by Rino Rappuoli, Mariagrazia Pizza, Audino Podda, Maria Teresa De Magistris and Luciano Nencioni 232 Common principles in protein folding and antigen presentation, by Shan Lu, Victor E. Reyes, Rochelle R. Torgerson, Robert E. Lew and Robert E. Humphreys 238 High performance capillary electrophoresis, by John Frenz and William S. Hancock 243 Analysing lymphokine—-receptor interactions of IL-1 and IL-2 by recombinant-DNA technology, by Gerard Zurawski 250 Book Reviews Beyond Mendel’s Garden: Biotechnology in the Service of World Agriculture (by Gabrielle J. Persley), by WinstonJ . Brill 257 Handling Laboratory Microorganisms (by Charles Penn), by Ken P. Flint 258 AUGUST Biotopics Stabilizing proteins ... with hybrid vigour, by MichaelJ . Geisow 259 Biosensors — a swell response to sugar, by MichaelJ . Geisow 260 Forum Workshop Biological pulping in paper manufacture, by Ian D. Reid Letters Stabilizing protein products: reflections on the glassy state, by Tony Auffret 265 Beyond antisense — How do transgenes interact with homologous plant genes? by Richard Jorgensen Focus pH gradients and membrane transport in liposomal systems, by P. R. Cullis, M. B. Bally, T. D. Madden, L. D. Mayer and M. J. Hope Reviews The kinetics of plasmid loss, by David K. Summers 273 Strategies for improving plasmid stability in genetically modified bacteria in bioreactors, by P. K. R. Kumar, H-E. Maschke, K. Friehs and K. Schiigerl 279 The nasal delivery of peptides and proteins, by Lisbeth Illum Book Reviews The Molecular and Cellular Biology of the Potato (edited by M. A. Vayda and W. D. Park), by Wayne Powell 290 Genes and Cancer (edited by Desmond Carney and Karol Sikora), by Herman van der Putten 291 Anaerobic Bacteria (by Paul N. Levitt), by Brian Watt SEPTEMBER Biotopics The importance of being a protein scientist, by MichaelJ . Geisow 293 Peptide synthesis — theme and variations, by MichaelJ .G eisow Forum Meeting reports Targeting peptides and proteins: NATO ASI, by Alexander T. Florence and Gregory Gregoriadis Biotechnology and sustainable development in the Third World, by Frits K. de Graaf Workshop Protein sequences — homologies and motifs, by MichaelJ .E . Sternberg and Suhail A. Islam Focus Retroelement particles as purification, presentation and targeting vehicles, by A. J. Kingsman, S. E. Adams, N. R. Burns and S. M. Kingsman Reviews Environmental regulation of bacterial virulence — implications for vaccine design and production, by Elwyn Griffiths Media additives for protecting freely suspended animal cells against agitation and aeration damage, by Eleftherios T. Papoutsakis Molecular biology of Erwinia: from soft-rot to antileukaemics, by Janine Robert-Baudouy Book Reviews Supplement The Terminology of Biotechnology: a Multidisciplinary Problem (edited by K. L. Loening), by MaxJ . Kennedy Planar Chromatography in the Life Sciences: Chemical Analysis Monographs Vol. 108 (edited by Joseph C. Touchstone), by I. D. Wilson Fundamentals of Protein Biotechnology (edited by Stanley Stein), by Michael] .G eisow In Vitro Methods for Conservation of Plant Genetic Resources (edited by John H. Dodds), by Michael F. Fay Advances in Human Genetics (edited by H. Harris and K. Hirschhorn), by N. K. Spurr Living Resources for Biotechnology — Animal Cells (edited by A. Doyle, R. Hay and B. E. Kirsop), by Caroline MacDonald Agricultural Biotechnology: Opportunities for International Development (edited by Gabrielle J. Persley), by Vaughan A. Hilder Chromosome Banding (by A. T. Sumner), by Michael G. Daker OCTOBER Biotopics DNA-based drugs, diagnostics and devices, by Michael] . Geisow Biotechnology — what does industry want from the science base? by MichaelJ .G eisow Forum Workshop Detection of nucleic acid hybridization using surface plasmon resonance, by Terek Schwarz, Debra Yeung, Edward Hawkins, Paul Heaney and Alex McDougall Meeting report Oligonucleotides: problems and frontiers of practical applications, by C. Héléne and T. Le Doan Focus Cofactor engineering, by Johannis A. Duine Reviews The role of N-linked oligosaccharides in glycoprotein function, by Alan D. Elbein Developing rDNA products for treatment of hemophilia A’, by RandalJ .K aufman The future impact of industrial lipases, by Fredrik Bjérkling, Sven Erik Godtfredsen and Ole Kirk Book Reviews Methods in Yeast Genetics: A Laboratory Course Manual (by Mark D. Rose, Fred Winston and Philip Heiter), by Derek J. Jamieson Large-Scale Mammalian Cell Culture Technology (edited by A. S. Lubiniecki), by A. Handa-Corrigan Genetically Engineered Organisms: Benefits and Risks (by J. R. S. Fincham and J. R. Ravetz), by Roger W. Pickup Modern Thin-Layer Chromatography (edited by Nelu Grinberg), by R. J. Ruane Books received “see Errata NOVEMBER Biotopics Biotechnology transfer: should administrations stimulate or steer? by MichaelJ . Geisow Both bane and blessing— inclusion bodies, by MichaelJ . Geisow Forum Workshop Undercooling — low temperature without freezing, by Sheila F. Mathias Meeting report Frontiers of biotechnology in agriculture, by Arie Altman Focus Bispecific antibodies for targeted cellular cytotoxicity, by Michael W. Fanger and Paul M. Guyre Reviews The molecular basis of partitioning in aqueous two-phase systems, by Jonathan Huddleston, Andres Veide, Kristina Kohler, Julia Flanagan, Sven-Olof Enfors and Andrew Lyddiatt Malaria vaccines — progress and problems, by Francis E. G. Cox Tailoring the microenvironment of enzymes in water-poor systems, by Bo Mattiasson and Patrick Adlercreutz Book Reviews Biotechnology in Agriculture and Forestry, Vol. 10, Legumes and Oilseed Crops | (edited by Y. P. S. Bajaj), by Paul Gepts In Situ Hybridization: Principles and Practice (edited by J. M. Polak and J. O’D. McGee), by John R. Gosden Process Measurement and Control, Vol. 1: On-line Estimation and Adaptive Control of Bioreactors (by G. Bastin and D. Dochain), by Glyn Hobbs Microbial Enzymes and Biotechnology; 2nd edn (edited by William M. Fogarty and Catherine T. Kelly), by Geoffrey Hazlewood DECEMBER Biotopics Unravelling the mysteries of molecular audit: MHC Class | restriction, by MichaelJ . Geisow Of mice and mimics, by MichaelJ .G eisow Forum Meeting reports A productive mix of cultures, by C. J. Mannix Cell-based assays — technology providing alternatives to animal testing, by C. Jane Robinson Focus Lichen-forming fungi: potential sources of novel metabolites, by Peter D. Crittenden and Neil Porter Poliovirus antigen chimeras, by Charlotte S. P. Rose and DavidJ .E vans Reviews Understanding and controlling detrimental bioreactor biofilms, by James D. Bryers Fluid-mechanical damage of animal cells in bioreactors, by Eleftherios T. Papoutsakis Book Reviews Supplement Molecular Systematics (edited by David M. Hillis and Craig Moritz), by Gabby A. Dover Japanese Biotechnology — A Comprehensive Study of Government Policy, R&D and Industry (by Robert T. Yuan and Mark D. Dibner), by Carl S. Jone Biotechnology in Japan Yearbook 1990/91: Markets and Research/Development (edited and co-published by Nikkei Biotechnology and Japan Pacific Associates), by Mark D. Dibner Animal Virus Pathogenesis — A Practical Approach (edited by Michael B. A. Oldstone), by Anthony Nash Advances in Microbial Physiology: Vol. 31 (edited by A. H. Rose and D. W. Tempest), byJ . Gareth Morris Physiology of the Bacterial Cell: A Molecular Approach (by F. C. Neidhart, J. L. Ingraham and M. Schaechter), by Elwyn Griffiths Bioinstrumentation — Research, Developments and Applications (edited by Donald L. Wise), by P. R. Coulet Understanding Enzymes, 3rd edn (by Trevor Palmer), by Bernard Henrissat Protein Engineering in Focus (by Peter C. E. Moody and Anthony J. Wilkinson), by Kenji Takabayashi Methods in Plant Biochemistry, Vol. 6; Assays for Bioactivity (edited by K. Hostettmann), by R. R. M. Paterson Plant Biotechnology Series: Vol. |, Plant Genetic Engineering; and Vol. Il, Developmental Regulation of Plant Gene Expression (both edited by Don Grierson), by John Bryant Safer Insecticides — Development and Use (edited by Ernest Hodgson and Ronald J. Kuhr), by WilliamJ .M oar Books received Errata Annexins — forms without function — but not without fun, by MichaelJ . Geisow, pp. 180-181 More about co-suppression, by Jos Mol, Rik van Blokland and Jan Kooter, pp. 182-183 Developing rDNA products for treatment of hemophilia A, by RandalJ .K aufman, pp. 353-359 Author Index Subject Index Index of Books Reviewed