The Mammalian Egg Coat: Structure and Function PDF
Preview The Mammalian Egg Coat: Structure and Function
Johannes Dietl (Ed.) The Mammalian Egg Coat Structure and Function Foreword by P.~.VVassarnnan VVith 66 Figures in 117 Separate Illustrations Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Priv.-Doz. Dr. med. Johannes Dietl Un iversiHits-Frauenklinik Eberhard-Karls-Universitat SchleichstraBe 4 0-7400 Tiibingen Federal Republic of Germany ISBN -13: 978-3-642-74050-3 e-ISBN -13: 978-3-642-74 048-0 001: 10.1007/978-3-642-74048-0 Library of Congress Cataloging-in-Publication Data The Mammalian egg coat. 1. Zona pellucida. 2. Mammals--Eggs. I. Dietl, Johannes, 1948- QL965.M33 1989 599'.033 88-34895 ISBN-13:978-3-642-74050-3 (U.S.) This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustra tions, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. Duplication of this publication or parts thereof is only permitted under the provisions of the German Copyright Law of September 9, 1965, in its version of June 24, 1985, and a copyright fee must always be paid. Violations fall under the prosecution act of the German Copyright Law. © Springer-Verlag Berlin Heidelberg 1989 Softcover reprint of the hardcover 1st edition 1989 The use of general descriptive names, trade marks, etc. in this publication, even if the for mer are not especially identified, is not to be taken as a sign that such names, as under stood by the Trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone. Product Liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. 2123/3145-543210 - Printed on acid-free paper To Anna Katharina Foreword Publication of this monograph acknowledges great strides made in research on the zona pellucida during the past decade or so. The body of work presented testifies to a resurgence of interest in the zona pellucida, prompted largely by a renewed appreciation of its unique properties and its important functions during early mam malian development. It is gratifying to realize that the zona pellucida has at last achieved a well-deserved attention. Whereas extracellular coats of nonmammalian eggs have been studied intensively for many years, the zona pellucida by comparison, has until now taken a back seat. Fortunately, the research presented here signals an end to this situ ation. Many of the difficulties inherent in working with relatively small amounts of material have been overcome, paving the way for application of a wider variety of experimental approaches to the zona pellucida by a larger community of investigators. Hopefully, this monograph will serve as a catalyst in this regard. As revealed in these pages, application of contemporary experi mental methodologies has had significant impact on both pure and applied research on the zona pellucida. For example, modem im munological approaches have been used to assess molecular fea tures of zona pellucida structure and function, as well as to evalu ate the zona pellucida as a potential contraceptive target antigen. Recombinant DNA technology, used thus far to clone zona pellu cida genes and study their expression, continues to hold much promise for future work on reproductive failure attributable to zo na pellucida dysfunction. Improved in vitro cell culture and bio chemical fractionation methodologies have been used to dissect the mammalian fertilization pathway, as well as to identify and characterize zona pellucida components involved in the pathway. Application of these and other experimental approaches to zona pellucida synthesis, structure, and function continues to reveal the molecular bases of zona pellucida functions during mammalian development. It has also revealed some novel ways in which to address practical problems in mammalian conception and contra ception. This monograph, devoted exclusively to the zona pellucida, provides an up-to-date, comprehensive assessment of the field. VIII Foreword However, it certainly will not be the final word on the subject. Fu ture research on the zona pellucida will undoubtedly reveal as yet unappreciated aspects of this unique organelle. I look forward to the next installment. Paul M. Wassarman Chairman Department of Cell and Developmental Biology Roche Institute of Molecular Biology Preface During growth of the ovarian follicle, the mammalian oocyte be comes surrounded by an acellular coat called the zona pellucida. Despite numerous morphological and biochemical studies, it has remained unresolved whether the zona pellucida originates from the oocyte, the follicle cells, or both. The past 10 years have seen the emergence of evidence supporting the idea that the zona pellu cida originates from the oocyte itself. The zona pellucid a mediates a number of important biological functions, including relatively species-specific binding of sperm to the ovulated eggs and postfer tilization blocking of polyspermy. Sperm-zona pellucida interac tion on a molecular basis is of inherent interest since it represents the first instance of cell-cell interaction during the development of a new individual. In recent years the application of immunocytochemical and molecular biological techniques to the study of sperm-zona pellu cida interaction has dramatically altered our concepts of gamete recognition. It is the aim of this book to present the reader with the most up-to-date information concerning the field of gamete inter action in reproductive biology. The molecular basis of the recep tor-mediated process of gamete recognition is described in detail. In addition, there is extensive discussion of the site of synthesis of the extracellular egg coat, which has been a matter of dispute for decades. The resolution of this problem with the aid of the meth ods of molecular biology is given due consideration. There is also a description of the ultrastructural appearance during development of the zona pellucida in the various stages of follicle maturation. Furthermore, particular glycoproteins present in the egg coat are discussed and their possible role with regard to immunological contraception is examined closely. Finally, the zona pellucida is put forward as the possible site of origin of immunological infertil ity. The subject matter of this book fills a gap in reproductive biol ogy research and thereby provides a link between the separate scientific discussion of the egg and of the sperm. Tubingen, December 1988 Johannes Dietl Table of Contents Molecular Genetics of the Mouse Zona Pellucida M. E. Chamberlin, M. J. Ringuette, C. C. Philpott, S. M. Chamow, and J. Dean . . . . . . . . . . . . . 1 The Mouse Egg Receptor for Sperm: A Multifunctional Zona Pellucida Glycoprotein P. Wassarman, J. Bleil, C. Fimiani, H. F/orman, J. Greve, R. Kinloch, C. Moller, S. Mortillo, R. Roller, G. Salzmann, and M. Vazquez ........ . . . . . . . . . . . . . . 18 Ovarian Development and the Formation of the Mammalian Zona Pellucida B. S. Dunbar, G.A. Maresh, and K. Washenik . . . . . . . . .. 38 Ultrastructural Aspects of the Developing Mammalian Zona Pellucida J.Dietl .............................. 49 Zona Binding Sites of the Spermatozoon R. B. L. Gwatkin ........ . . . . . . . . . . . . . . . . . 61, Fractionation and Characterization of the Glycoproteins of Zona Pellucida M.Nakano ............................ 75 Transfer of Oviductal Proteins to the Zona Pellucida G. Bleau and S. St-Jacques. . . . . . . . . . . . . . . . . . .. 99 Clinical Significance of Autoantibodies to the Zona Pellucida Takahide Mon, K. Ida, Y. Noda, H. Matsumoto, Tsuneatsu Mon, and E. Mon. . . . . . . . . . . . . . . . . . . 111 Use of the Zona Pellucida as an Immunocontraceptive Target Antigen A. G. Sacco and E. C. Yurewicz . . . . . . . . . . . . . . .. . 128 Subject Index ......................... . 155 List of Contributors Bleau, G. Department of Obstetrics and Gynecology, Universite de Montreal, Maisonneuve-Rosemont Research Center, 5415, boul. de l'Assomption, Montreal, Canada, H1T 2M4 Bleil, J. Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Roche Research Center, Nutley, NJ 07110, USA Chamberlin, M. E. Laboratory of Cellular and Developmental Biology, Building 6, Room 81-08, NIDDK National Institutes of Health, Bethesda, MD 20892, USA Chamow, S. M. Laboratory of Cellular and Developmental Biology, Building 6, Room 81-08, NIDDK National Institutes of Health, Bethesda, MD 20892, USA Dean, J. Laboratory of Cellular and Developmental Biology, Building 6, Room 81-08, NIDDK National Institutes of Health, Bethesda, MD 20892, USA Dietl, J. Department of Obstetrics and Gynecology, Eberhard-Karls Universitat, Schleichstra13e 4, D-7400 Tiibingen, Federal Republic of Germany Dunbar, B.S. Department of Cell Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA Fimiani, C. Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Roche Research Center, Nutley, NJ 07110, USA XIV List of Contributors Florman. H. Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Roche Research Center, Nutley, NJ 07110, USA Greve. J. Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Roche Research Center, Nutley, NJ 07110, USA Gwatkin. R. B. L. Reproductive and Developmental Biology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44106, USA Ida. K. Department of Gynecology and Obstetrics, Faculty of Medicine, Kyoto University, Kyoto, Japan Kinloch. R. Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Roche Research Center, Nutley, NJ 07110, USA Maresh. G.A. Department of Cell Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA Matsumoto, H. Department of Gynecology and Obstetrics, Faculty of Medicine, Kyoto University, Kyoto, Japan Moller. C. Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Roche Research Center, Nutley, NJ 07110, USA Mori. E. Division of Immunology, Institute of Medical Science, Tokyo University, Tokyo, Japan Mori, Takahide Department of Gynecology and Obstetrics, Faculty of Medicine, Kyoto University, Kyoto, Japan Mori. Tsuneatsu Division of Immunology, Institute of Medical Science, Tokyo University, Tokyo, Japan
The list of books you might like
