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About T Cell Subsets: Cellular Selection, Commitment and Identity
This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers
Detailed Information
| Author: | Harvey Cantor, Laurie Glimcher, and Frederick W. Alt (Eds.) |
|---|---|
| Publication Year: | 2004 |
| Pages: | 331 |
| Language: | English |
| File Size: | 4.062 |
| Format: | |
| Price: | FREE |
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