Submitted during the course of DM Cardiothoracic and Vascular Anaesthesia

117 Pages·2016·4.4 MB·English

“Intraoperative Assessment Of Transient And Persistent Regional Left
Ventricular Wall Motion Abnormalities In Patients Undergoing Coronary
Revascularization Surgery Using Real-time 3D Echocardiography”
A Prospective Observational Study

PROJECT REPORT

Submitted during the course of
DM Cardiothoracic and Vascular Anaesthesia

Dr. Neelam Aggarwal
Senior Resident

DEPARTMENT OF ANESTHESIOLOGY
Jan 2014 – Dec 2016

i
DECLARATION

I, Dr. Neelam Aggarwal, hereby declare that the project in this book was undertaken by
me under the supervision of the faculty, Department of Anaesthesiology (Cardiothoracic &
Vascular Anaesthesia), Sree Chitra Tirunal Institute for Medical Sciences and Technology.

Thiruvananthapuram Dr Neelam Aggarwal
Date Senior Resident

Forwarded

The candidate, Dr Neelam Aggarwal, has carried out the minimum required project.

Thiruvananthapuram Prof. Dr Rupa Sreedhar
Date Prof. of Department of Anaesthesiology

ii
CERTIFICATE

This is to certify that this project entitled “Intraoperative Assessment Of Transient and
Persistent Regional Left Ventricular Wall Motion Abnormalities In Patients Undergoing
Coronary Revascularization Surgery Using Real-time 3D Echocardiography”, has been
prepared by Dr. Neelam Aggarwal, a D.M cardiothoracic and vascular anaesthesia resident
under the guidance of Dr. Koniparambil P Unnikrishnan, Professor, Department of
Anaesthesiology and under my overall supervision and Guidance at Sree Chitra Tirunal Institute
for medical sciences and technology , Trivandrum. She has shown keen interest in preparing this
project.

Place : Dr. Rupa Sreedhar
Date : Professor and HOD,
Department of anaesthesiology,
SCTIMST, Trivandrum.

iii
CERTIFICATE

This is to certify that this project entitled “Intraoperative Assessment of Transient and
Persistent Regional Left Ventricular Wall Motion Abnormalities In Patients Undergoing
Coronary Revascularization Surgery Using Real-time 3D Echocardiography”, has been
prepared by Dr. Neelam Aggarwal, a D.M cardiothoracic and vascular anaesthesia resident and
has been done under my direct guidance and supervision at Sree Chitra Tirunal Institute for
medical sciences and technology, Trivandrum. She has shown keen interest in preparing this
project.

Place : Dr. Koniparambil P Unnikrishnan
Date : Professor,
Department of anaesthesiology,
SCTIMST, Trivandrum.

iv
CERTIFICATE

This is to certify that this project entitled “Intraoperative Assessment of Transient and
Persistent Regional Left Ventricular Wall Motion Abnormalities In Patients Undergoing
Coronary Revascularization Surgery Using Real-time 3D Echocardiography”, has been
prepared by Dr. Neelam Aggarwal, a D.M cardiothoracic and vascular anaesthesia resident at
Sree Chitra Tirunal Institute for medical sciences and technology, Trivandrum. She has shown
keen interest in preparing this project.

CO-GUIDE CO-GUIDE

Dr. Puthuvasseri R Suneel Dr. Jayakumar K
Professor, Professor and Head,
Department of anaesthesiology, Department of Cardiac Surgery
SCTIMST, Trivandrum. SCTIMST, Trivandrum.

v
ACKNOWLEDGEMENT

I am deeply indebted to my guide Prof. Koniparambil P Unnikrishnan for his
tremendous encouragement and constructive criticism throughout the course of this study.
I am very grateful to my co-guide Prof. P.R. Suneel for his constant encouragement and
valuable suggestions at all stages of this study.
I owe my sincere thanks to Prof. Rupa Sreedhar who showered her unconditional help and
faith in me.
I express my gratitude to Prof. Jayakumar K for his guidance and motivation throughout the
course of my study.

I am always indebted to my Parents for their blessings and support in completing the study.
I owe heartfelt thanks to Monika Aggarwal (my sister) and Pankaj Aggarwal (my brother)
who have helped me in a multitude of ways for making me feel confident during the study.

I am also grateful to Prof. Thomas Koshy and Shrinivas .V. Gadhinglajkar for their
cooperation and motivation during every phase of my study.
I owe a special thanks to my friend Dr Indranil Biswas for his unconditional help during this
study.
I sincerely thank all my colleagues of the department and anaesthesia technicians for their
constant help.
I am deeply indebted to my patients for their cooperation and sacrifices for the greater good of
fellow human beings.

v
Dedicated to my beloved sister Monika Aggarwal and my family

vi
TABLE OF CONTENTS

CHAPTER TITLE PAGE
NO. NO.

LIST OF FIGURES ix
LIST OF TABLES xi
LIST OF ABBREVIATIONS xii

1 INTRODUCTION 01
2 AIMS AND OBJECTIVES 04

3 REVIEW OF LITERATURE 05
3.1 Pathogenesis and identification of transient and 05
persistent RWMA
3.2 Intraoperative 2D TEE assessment of RWMA 07
3.3 Intraoperative RT3DE 10
3.4 Concept of Intra-ventricular dyssynchrony 11
3.5 Parametric Motion Imaging 13

vii
4 MATERIALS AND METHODS 15
5 STATISTICAL ANALYSIS 21

6 OBSERVATION AND RESULTS 22
7 DISCUSSION 41
8 54
LIMITATIONS
9 55
CONCLUSION

BIBLIOGRAPHY 56

ANNEXURE

viii
LIST OF FIGURES

FIGURE TITLE PAGE NO
NO.
1 Pre-Cardiopulmonary bypass Scatter Plot between SDI 24
and WMSI
2 A flow chart: Division of patients in groups and 26
subgroups based on TEE findings
3 Parametric bull’s eye image showing Early Activating 27
Segments
4 Parametric bull’s eye image showing Stunned 28
myocardium
5 Parametric bull’s eye image showing Perfusion- 29
Contraction mismatch
6 Parametric bull’s eye image showing full recovery of 31
hibernating segments
7 Parametric bull’s eye image showing no recovery of 32
infarcted segments
8 Parametric bull’s eye image showing: 33
B) Failure of RT3DE to detect RWMA in case of graft
dysfunction
C) Anterior wall dyskinesia due to graft dysfunction 35
ix