Samir S. Shah • Jeanine C. Ronan • Brian Alverson 1800+ Quick Hit~ and Mnemunit~ high light k ') fat'l~ fur tlu p,·dialrks dt·tkship. sh<·ll ams, :md tlw U 11 L Stq > l f' linical hox ·s cast• the u. nsit1on from bask sClt'nt • 10 clinicaln1 "dicinr 200+ clini al bo~cs and tahlt's facilitat(• Est rc\·icw 40 l+ online l _ Mt.l~·st)'IC <tucstitlll'. \\ith complete (•xplanat ions • -· up • Wolters Klw.er lltppmcou Wtlliams & W'•l s Step .. S. I S STEP-UP TO Samir S. Shah, MD, MSCE Director, Division of Hospital Medicine Attending Physician, Divisions of Hospital Medicine and Infectious Diseases Cincinnati Children's Research Foundation Endowed Chair in Hospital Medicine Cincinnati Children's Hospital Medical Center Professor, Department of Pediatrics University of Cincinnati College of Medicine Cincinnati, Ohio Jeanine C. Ronan, MD Assistant Professor of Clinical Pediatrics Co-Director, Pediatrics Clerkship Perelman School of Medicine atthe University of Pennsylvania Attending Physician Division of General Pediatrics Children's Hospital of Philadelphia Philadelphia, Pennsylvania Brian Alverson. MD Director, Division of Pediatric Hospital Medicine Hasbro Children's Hospital Associate Professor, Department of Pediatrics The Warren Alpert School of Medicine at Brown University Providence, Rhode Island I . Wolters Kluwer Lippincott Williams & Wilkins Health Philadelphi:a • Balttmore • New York • london Bu•nos Aires o Hong Kong o Sydney o Tokyo Publisher: Michael Tully Acquisitions Editor: Tari Broderick Product Development Editor: Jennifer Verbiar Marketing Manager: Joy Fisher-Williams Designer: Holly Reid McLaughlin Production Manager: Priscilla Crater Compositor: Absolute Service, Inc. 1st Edition Copyright© 2014 Lippincott Williams &: Wilkins, a Wolters Kluwer business. 351 West Camden Street Two Commerce Square Baltimore, MD 21201 2001 Market Street Philadelphia, PA 19103 Printed in China All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any fonn or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any infonnation storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by indi viduals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Lippincott Williams &: Wilkins at 2001 Market Street, Philadelphia, PA 19103, via email at [email protected], or via website at lww.com (products and services). 9 8 7 6 5 4 3 2 1 Library of Congress Cataloging-in-Publication Data Shah, Samir S., author. Step-up to pediatrics I Samir S. Shah, Jeanine C. Ronan, Brian Alverson. - First edition. p.; em. - (Step-up series) Includes index. Summary: "A guide for third year medical students preparing for the end-of-rotation NBME shelf exam, the pediatrics clerkship, and the USMLE Step 2 CK"-Provided by publisher. ISBN 978-1-4511-4580-9 (paperback) I. Ronan, Jeanine C., author. II. Alverson, Brian., author. m. Title. IV. Series: Step up series. IDNLM: 1. Pediatrics-Outlines. 2. Pediatrics-Problems and Exercises. 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Lippincott Williams&: Wilkins customer service representatives are available from 8:30 am to 6:00 pm, EST. GIL BINENBAUM, MD, MSCE AMY EUZABBTH FLEMING, MD Diseases of the Eye Dermatologic Conditions Assistant Professor Associate Professor Department of Ophthalmology Division of Hospital Medicine Perelman School of Medicine at the Director of Medical Student Education University of Pennsylvania Department of Pediatrics Attending Surgeon Vanderbilt University School of Medicine Department of Ophthalmology Monroe Carell Jr. Children's Hospital Children's Hospital of Philadelphia Nashville, Tennessee Philadelphia, Pennsylvania MATiliEW GARB~ MD APRIL 0. BUCHANAN, MD Diseases of the Pulmonary System Diseases of the Gastrointestinal System Associate Professor Associate Professor of Oinical Pediatrics Department of Pediatrics Academic Director, Years 3 and 4 University of South Carolina School of Medicine University of South Carolina School of Medicine Director of Pediatric Hospitalists Greenville Department of Pediatrics Pediatric Hospitalist Palmetto Health Children's Hospital Department of Pediatrics Columbia, South Carolina Greenville Health System Greenville, South Carolina DOUGLAS HARRISON, MD Hematologic Diseases DOUGLAS W. CARLSON, MD Oncolcgic Diseases Infectious Diseases Assistant Professor of Pediatrics Professor of Pediatrics The Warren Alpert School of Medicine Department of Pediatrics at Brown University Washington University Pediatric Hematologist Oncologist Director, Division of Hospital Medicine Department of Pediatrics Department of Pediatrics Hasbro Children's Hospital St. Louis Children's Hospital Providence, Rhode Island St. Louis, Missouri MEENA IYER, MD DANIEL T. COGIH.IN, MD Neurologic Disorders Fluids and Electrolytes Assistant Professor of Pediatrics Clinical Assistant Professor of Pediatrics Department of Pediatrics The Warren Alpert School of Medicine University of Texas Southwestern-Austin at Brown University Medical Director, Hospital Medicine Pediatric Hospitalist Dell Children's Medical Center of Central Texas Department of Pediatrics Austin, Texas Hasbro Children's Hospital Providence, Rhode Island v vi • SECTION EDITORS EUZABETH A. JAMME, MD RICARDO A. QUINONEZ, MD, FAAP, FHM Developmental and Behavioral Disorders Alkrgic and Immunologic Disorders Clinical Assistant Professor Associate Professor of Pediatrics Department of Pediatrics Chief PereJman School of Medicine at the Division of Pediatric Hospital Medicine University of Pennsylvania Children's Hospital of San Antonio Pedia1ric Hospitalist Baylor College of Medicine Department of General Pedia1rics San Antonio, Texas Children's Hospital of Philadelphia Philadelphia, Pennsylvania JOSE BERNARDO QUINTOS, MD Endocrine and Metabolic Diseases J. LEONARD LEVINE, MD Assistant Professor of Oinical Pediatrics Diseases Unique to Adolescent Medicine Department of Pediatrics Associate Professor of Pedia1rics Division of Pediatric Endocrinology Assistant Chair for Medical Student Education in The Warren Alpert School of Medicine Pediatrics at Brown University Director, Pediat:rics Clerkship and Pediatrics Pathway Pediatric Endocrinologist Diredor, Program for Integrated Learning Small Division of Pediatric Endocrinology Group Process Rhode Island Hospital Drexel University College of Medicine Providence, Rhode Island Philadelphia, Pennsylvania STACEY R. ROSE, MD VINEETA MI'ITAL, MD, FAAP Disorders oft~ Ear, Nose, and Throat Diseases Unique to the Newborn Clinical Assistant Professor of Pediatrics Associate Professor of Pedia1rics Department of Pediatrics Department of Pediatrics Perelman School of Medicine at the Academic Colleges Mentor University of Pennsylvania University of Texas Southwestern Medical Center Attending Physician Pediatric Hospitalist Division of General Pediat:rics Department of Pediatrics Children's Hospital of Philadelphia Children's Medical Center Philadelphia, Pennsylvania Dallas, Texas MARK W. SHEN, MD FRANCES M. NADEL, MD, MSCE Neurologic Disorders Emergency Medicine, Critical Care, Toxicology, and Child Associate Professor of Pediatrics Abuse Department of Pediatrics Professor of Clinical Pediatrics University of Texas SouthwEStern-Austin Department of Pediatrics Pediatric Hospitalist PereJman School of Medicine at the Dell Children's Medical Center of Central Texas University of Pennsylvania Austin, Texas Attending Physician Division of Emergency Medicine NATASHA SHUR, MD Children's Hospital of Philadelphia Dysmorphology and Genetic Disorders Philadelphia, Pennsylvania Assistant Professor Department of Pediatrics JENNIFER K. O'TOOLE, MD, MEd The Warren Alpert School of Medicine Diseases of the Renal and Genitourinary System at Brown University Associate Director, Internal Medicine and Pediatrics Attending, Clinical Geneticist Residency Training Program Department of Pediatrics Medical Director of Education, Division of Hospital Rhode Island Hospital Medicine Providence, Rhode Island Cincinnati. Children's Hospital Medical Center and The University of Cincinnati Medical Center Assistant Professor of Internal Medicine and Pediatrics University of Cincinnati College of Medicine Cincinnati, Ohio SECTION EDITORS e vii JENNIFER BETII SOEP, MD SUSANWU,MD Rheumatologic Disorders and Orthopedic Conditions Diseases of the Cardiovascular System Associate Professor Assistant Professor of Clinical Pediatrics Department of Pediatric Rheumatology Department of Pediatrics University of Colorado University of Southern California Children's Hospital of Colorado K~k School of Medicine Aurora, Colorado Department of Pediatrics Division of Hospital Medicine Children's Hospital Los Angeles LosAnge~,Ca1ifonna DIANNE ABUELO, MD MAROUN AZAR, MD Associate Professor Assistant Professor Department of Pediatrics Department of Medicine The Warren Alpert School of Medicine The Warren Alpert School of Medicine at Brown University at Brown University Director, Genetic Counseling Center Nephrologist Department of Pediatrics Department of Medicine Rhode Island Hospital Rhode Island Hospital Providence, Rhode Island Providence, Rhode Island ENITAN ADEGITE, MD, MPH FRANCES BALAMUTII, MD, PhD Assistant Professor Assistant Professor Department of Pediatrics Department of Pediatrics Drexel University College of Medicine Perelman School of Medicine at the Attending Physician University of Pennsylvania Department of Adolescent Medicine Attending Physician St. Christopher's Hospital for Children Division of Emergency Medicine Philadelphia, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania SOUMYA ADHIKARI, MD Assistant Professor of Pediatrics M. RYAN BALLARD, PA.C Division of Endocrinology Faculty Department of Pediatrics Department of Pediatric Orthopedics Pediatric Clerkship Director University of Colorado Department of Pediatrics Physician Assistant University of Texas Southwestern Medical Center Department of Pediatric Orthopedics Attending Physician Children's Hospital of Colorado Department of Pediatrics Aurora, Colorado Children's Medical Center Dallas, Texas KATHLEEN W. BARTLETT, MD Associate Professor LILLIAM V. AMBROGGIO, PhD Department of Pediatrics Assistant Professor of Pediatrics Duke University School of Medicine Division of Hospital Medicine Pediatric Hoepitalist Cincinnati Children's Hospital Medical Center Department of Pediatrics Department of Pediatrics Duke University Medical Center University of Cincinnati College of Medicine Durham, North Carolina Cincinnati, Ohio KEVIN BARTON, MD Instructor of Pediatrics ZOLTAN ANTAL, MD Division of Hospitalist Medicine Assistant Professor Washington University School of Medicine Department of Pediatric Endocrinology St Louis, Missouri Weill CorneD Medical College Attending Physician Department of Pediatric Endocrinology NewYork Presbyterian Hospital New York, New York viii