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www.medilibros.com S T E P -U P TO O S S TETñJC S AMD G Y N E C O L O G Y www.medilibros.com STEP-UP O B S T F J m « JD gynecology Frank W. Ling, MD Sandra Ann Carson, MD Clinical Professor Adjunct Professor of Obstetrics and Gynecology Department of Obstetrics and Gynecology Alpert Medical School of Brown University Vanderbilt University School of Medicine and Meharry Providence, Rhode Island Medical College Director, American Board of Obstetrics and Gynecology Nashville, Tennessee Dallas, Texas Partner, Women’s Health Specialists Germantown, Tennessee Wesley C. Fowler, Jr., MD Director, The Foundation for Exxcellence in Women's Associate Dean for Medical Alumni Affairs Health Care Professor of Obstetrics And Gynecology Dallas, Texas University of North Carolina School of Medicine Russell R. Snyder, MD Chapel Hill, North Carolina President, The Foundation for Exxcellence in Women's Vice-Chair and Director, Division of Gynecology Health Care Department of Obstetrics and Gynecology Dallas, Texas University of Texas Medical Branch Galveston, Texas Director, The Foundation for Exxcellence in Women's Health Care Dallas, Texas ^■j Woiters Kluwer Health Philadelphia • Baltimore • New York • London Buenos Aires • Hong Kong • Sydney • Tokyo Acquisitions Editor: Tari Broderick Product Development Editor: Jennifer Verbiar Production Project Manager: Marian Bellus Design Coordinator: Holly McLaughlin Manufacturing Coordinator: Margie Orzech Prepress Vendor: Absolute Service, Inc. 1st Edition Copyright © 2015 Wolters Kluwer Health | Lippincott Williams & Wilkins. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by indi viduals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer Health at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at [email protected], or via our website at lww.com (products and services). 987654321 Printed in China Library of Congress Cataloging-in-Publication Data Step-up to obstetrics and gynecology / [edited by] Frank W. Ling, Russell R. Snyder, Sandra Ann Carson, Wesley C. Fowler. — 1st edition, p.; cm. — (Step-up series) Includes bibliographical references and index. ISBN 978-1-4511-1244-3 (alk. paper) I. Ling, Frank W., editor. II. Snyder, Russell R. editor. III. Carson, Sandra A. (Sandra Ann), editor. IV. Fowler, Wesley C., Jr., 1940- editor. V. Series: Step up series. [DNLM: 1. Pregnancy Complications—Examination Questions. 2. Pregnancy Complications—Outlines. 3. Genital Diseases, Female—Examination Questions. 4. Genital Diseases, Female—Outlines. WQ 18.2] RG111 618.076—dc23 2014008800 Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices. However, the author(s), editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the publication. Application of this information in a particular situation remains the professional responsibility of the practitioner; the clinical treat ments described and recommended may not be considered absolute and universal recommendations. The author(s), editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with the current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug. Some drugs and medical devices presented in this publication have Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in his or her clinical practice. LWW.com L Section Editors FRANK W. LING, MD SANDRA ANN CARSON, MD Section 2: Obstetrics Section 4: Reproductive Endocrinology and Infertility Clinical Professor Adjunct Professor of Obstetrics and Gynecology Department of Obstetrics and Gynecology Alpert Medical School of Brown University Vanderbilt University School of Medicine and Providence, Rhode Island Meharry Medical College Director, American Board of Obstetrics and Nashville, Tennessee Gynecology Partner, Women's Health Specialists, PLLC Dallas, Texas Germantown, Tennessee Director, The Foundation for Exxcellence in Women's WESLEY C. FOWLER, JR., MD Health Care Section 5: Gynecologic Oncology Dallas, Texas Associate Dean for Medical Alumni Affairs Professor of Obstetrics And Gynecology RUSSELL R. SNYDER, MD University of North Carolina School of Medicine Section 1: Overview of Women's Health Chapel Hill, North Carolina Section 3: Gynecology President, The Foundation for Exxcellence in Vice-Chair and Director, Division of Gynecology Women's Health Care Department of Obstetrics and Gynecology Dallas, Texas University of Texas Medical Branch Galveston, Texas Director, The Foundation for Exxcellence in Women's Health Care Dallas, Texas v Contributing Authors ✓ MICHAEL T. ADLER, MD BETTY CHOU, MD Chapter 25: Postterm Pregnancy and Intrauterine Fetal Chapter 16: Common Medical and Surgical Problems in Demise Pregnancy Chapter 26: Obstetric Procedures Chapter 20: Fetal Growth Abnormalities: Fetal Growth Assistant Professor of Obstetrics and Gynecology Restriction and Macrosomia Department of Obstetrics and Gynecology Director, Johns Hopkins Women's Services at University of Texas Medical School at Houston Odenton Houston, Texas Assistant Professor Department of Obstetrics and Gynecology PAMELA D. BERENS, MD Johns Hopkins Bayview Medical Center Chapter 2: The Obstetrician/Gynecologist's Role in Baltimore, Maryland Screening and Preventive Care Chapter 14: Postpartum Care/Complications ALICE CHUANG, MD Professor, Vice Chair of Clinical Affairs Chapter 45: Cell Biology and Principles of Cancer Department of Obstetrics and Gynecology Therapy University of Texas Medical School at Houston Chapter 46: Gestational Trophoblastic Neoplasia Houston, Texas Chapter 50: Ovarian and Adnexal Disease Associate Professor MOSTAFA A. BORAHAY, MD, FACOG Department of Obstetrics and Gynecology Chapter 34: Dysmenorrhea and Chronic Pelvic Pain University of North Carolina Assistant Professor Chapel Hill, North Carolina Women's Reproductive Health Research (WRHR) Scholar LESLIE CLARK, MD Department of Obstetrics and Gynecology Chapter 45: Cell Biology and Principles of Cancer University of Texas Medical Branch Therapy Galveston, Texas Resident Department of Obstetrics and Gynecology University of North Carolina AMY M. BURKETT, MD Chapel Hill, North Carolina Chapter 18: Hypertension in Pregnancy Department of Obstetrics and Gynecology BRENDAN D. CONNEALY, MD Summa Health Systems Chapter 6: Endocrinology of Pregnancy Northeastern Ohio Universities College of Chapter 12: Immediate Care of Newborn Medicine MFM Fellow Akron, Ohio Department of Obstetrics and Gynecology University of Texas Medical School at Houston CHRISTINNE CANELA, MD Houston, Texas Chapter 41: Hirsutism and Virilization Physician Director of Medical Quality DOUGLAS R. DANFORTH, PHD Department of Obstetrics and Gynecology Chapter 5: Reproductive Physiology Carilion Roanoke Memorial Hospital Associate Professor Roanoke, Virginia Department of Obstetrics and Gynecology The Ohio State University Medical Center Columbus, Ohio CONTRIBUTING AUTHORS • VÍ¡ JILL EDWARDSON, MD, MPH JAOU-CHEN HUANG, MD Chapter 16: Common Medical and Surgical Problems in Chapter 43: Infertility Pregnancy Reproductive Endocrinologist Assistant Professor Department of Obstetrics and Gynecology Department of Obstetrics and Gynecology Memorial Hermann Hospital Johns Hopkins Medical Center Houston, Texas Baltimore, Maryland NANCY A. HUEPPCHEN, MD CYNTHIA B. EVANS, MD Chapter 16: Common Medical and Surgical Problems Chapter 42: Menopause in Pregnancy Associate Professor Chapter 20: Fetal Growth Abnormalities: Fetal Growth Department of Obstetrics and Gynecology Restriction and Macrosomia The Ohio State University Medical Center Director of Medical Education Columbus, Ohio Associate Professor Department of Obstetrics and Gynecology JASON FRANASIAK, MD Johns Hopkins University School of Medicine Chapter 49: Cancer of the Uterine Corpus Baltimore, Maryland Physician at Reproductive Medicine Associates of New Jersey PATRICIA HUGUELET, MD, FACOG Obstetrics and Gynecology Chapter 17: Infectious Diseases in Pregnancy Gladstone, New Jersey Assistant Professor Department of Obstetrics and Gynecology MELISSA M. GOIST, MD University of Colorado, Anschutz Medical Center Chapter 15: Ectopic Pregnancy Aurora, Colorado Assistant Professor Department of Obstetrics and Gynecology ANDREW F. HUNDLEY, MD The Ohio State University Medical Center Chapter 32: Pelvic Support Defects, Urinary Columbus, Ohio Incontinence, and Urinary Tract Infection Division Director, Female Pelvic Medicine and SUSAN GOLDSMITH, MD Reconstructive Surgery Chapter 8: Preconception and Antepartum Care Department of Obstetrics and Gynecology Assistant Professor The Ohio State University Medical Center Department of Obstetrics and Gynecology Columbus, Ohio Northwestern University Feinberg School of Medicine Chicago, Illinois MICHELLE M. ISLEY, MD, MPH Chapter 28: Sterilization MATTHEW GRACE, MD Assistant Professor Chapter 47: Benign Vulvar Disease Department of Obstetrics and Gynecology Assistant Professor The Ohio State University Medical Center Department of Obstetrics and Gynecology Columbus, Ohio University of North Carolina Chapel Hill, North Carolina CHERYL J. JOHNSON, MD Chapter 1: The Woman's Health Examination CATHERINE HANSEN, MD, MPH Department of Obstetrics and Gynecology Chapter 37: Sexual Function and Dysfunction Summa Health System Assistant Professor Ohio State University Department of Obstetrics and Gynecology Akron, Ohio University of Texas Medical Branch Galveston, Texas BENJAMIN A. KASE, MD Chapter 7: Maternal-Fetal Physiology GERI D. HEWITT, MD Department of Obstetrics and Gynecology Chapter 39: Puberty Tripler Army Medical Center Assistant Professor Honolulu, Hawaii Department of Obstetrics and Gynecology The Ohio State University Medical Center Columbus, Ohio viii • CONTRIBUTING AUTHORS AMANTIA KENNEDY, MD SILKA PATEL, MD Chapter 46: Gestational Trophoblastic Neoplasia Chapter 13: Abnormal Labor and Malpresentation Assistant Professor Assistant Professor Department of Obstetrics and Gynecology Department of Obstetrics and Gynecology University of North Carolina Johns Hopkins School of Medicine Chapel Hill, North Carolina Baltimore, Maryland SAMI GOKHAN KILIC, MD, FACOG, FACS PAMELA A. PROMECENE, MD Chapter 36: Gynecologic Procedures Chapter 3: Ethics in Obstetrics and Gynecology Assistant Professor Chapter 10: Normal Labor and Delivery Department of Obstetrics and Gynecology Associate Professor of Obstetrics and Gynecology- University of Texas Medical Branch Clinical Galveston, Texas Assistant Dean for Graduate Medical Education Department of Obstetrics and Gynecology EDUARDO LARA-TORRE, MD University of Texas Medical School at Houston Chapter 41: Hirsutism and Virilization Houston, Texas Chapter 44: Premenstrual Syndrome and Premenstrual Dysphoric Disorder TRACY L. PROSEN, MD Residency Program Director Chapter 19: Multifetal Gestation Department of Obstetrics and Gynecology Assistant Professor Carilion Roanoke Memorial Hospital Department of Obstetrics, Gynecology and Women's Roanoke, Virginia Health University of Minnesota FRANK W. LING, MD Minneapolis, Minnesota Chapter 35: Breast Disorders Clinical Professor KELLIE S. RATH, MD Department of Obstetrics and Gynecology Chapter 4: Embryology and Anatomy Vanderbilt University School of Medicine and OhioHealth Gynecologic Cancer Surgeons Meharry Medical College Columbus, Ohio Nashville, Tennessee Partner, Women's Health Specialists BRITTON D. RINK, MD Germantown, Tennessee Chapter 9: Prenatal Diagnosis, Genetic Disorder Director, The Foundation for Exxcellence in Women's Assessment, and Teratology Health Care Director, Prenatal Genetics and Ultrasound Dallas, Texas Assistant Professor Department of Obstetrics and Gynecology QUINN LIPPMANN, MD, MPH The Ohio State University Medical Center Chapter 48: Cervical Dysplasia and Carcinoma Columbus, Ohio Oth Post-MD Department of Reproductive Medicine ANA M. RODRIGUEZ, MD University of California San Diego Chapter 27: Contraception San Diego, California Assistant Professor Department of Obstetrics and Gynecology AMANDA B. MURCHISON, MD University of Texas Medical Branch Chapter 22: Preterm Labor Galveston, Texas Chapter 23: Third-Trimester Bleeding Assistant Residency Program Director JACQUELINE ROHL, MD, MPH Department of Obstetrics and Gynecology Chapter 29: Reproductive Tract Congenital Carilion Roanoke Memorial Hospital Anomalies Roanoke, Virginia Assistant Professor Department of Obstetrics and Gynecology JESSICA L. NYHOLM, MD The Ohio State University Medical Center Chapter 11: Intrapartum Fetal Surveillance Columbus, Ohio Assistant Professor Department of Obstetrics, Gynecology and Women's Health University of Minnesota Minneapolis, Minnesota

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"Step-Up to Ob/Gyn is a primary review tool to prepare students for both the Ob/Gyn clerkship and the end-rotation NBME shelf examination. Texts in this series blend a bullet-outline format with comprehensive paragraphs, as needed, for optimal study and rotation preparation. Illustrations, charts, t