(cid:2) TrimSize:156mmx234mm Arifi ffirs.tex V3-03/04/2016 3:23pm Pagei SPATIAL AGENT-BASED SIMULATION MODELING IN PUBLIC HEALTH (cid:2) (cid:2) (cid:2) (cid:2) TrimSize:156mmx234mm Arifi ffirs.tex V3-03/04/2016 3:23pm Pageii Wiley Series in Modeling and Simulation MissionStatement TheWileySeriesinModelingandSimulationprovidesaninterdisciplinaryandglobalapproachtothe numerousreal-worldapplicationsofmodelingandsimulation(M&S)thatarevitaltobusinessprofes- sionals,researchers,policymakers,programmanagers,andacademicsalike.Writtenbyrecognized internationalexpertsinthefield thebookspresentthebestpracticesintheapplicationsofM&Sas wellasbridgethegapbetweeninnovativeandscientificall soundapproachestosolvingreal-world problemsandtheunderlyingtechnicallanguageofM&Sresearch.Theseriessuccessfullyexpands thewayreadersviewandapproachproblemsolvinginadditiontothedesign,implementation,and evaluation of interventions to change behavior. 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AdvisoryEditors•PublicandPopulationHealth PeterS.Hovmand,WashingtonUniversityinSt.Louis BruceY.Lee,UniversityofPittsburgh FoundingSeriesEditors JoshuaG.Behr,OldDominionUniversity RafaelDiaz,OldDominionUniversity HomelandSecurity,EmergencyManagement,andRiskAnalysis (cid:2) (cid:2) ForthcomingTitles Zedda•RiskandStabilityofBankingSystems Interoperability,Composability,andFormalism OperationsResearch,Logistics,SupplyChains,andTransportation PublicandPopulationHealth Arifin Madey,andCollins•SpatialAgent-BasedSimulationModelinginPublicHealth: Design,Implementation,andApplicationsforMalariaEpidemiology ForthcomingTitles Hovmand•ModelingSocialDeterminantsofHealth KimandHammon•ModelingandSimulationforSocialEpidemiologyandPublicHealth TrainingandEducation Combs,Sokolowski,andBanks•TheDigitalPatient:AdvancingHealthcare,Research,and Education ForthcomingTitles TolkandÖren•TheProfessionofModelingandSimulation (cid:2) (cid:2) TrimSize:156mmx234mm Arifi ffirs.tex V3-03/04/2016 3:23pm Pageiii SPATIAL AGENT-BASED SIMULATION MODELING IN PUBLIC HEALTH Design, Implementation, and Applications for Malaria Epidemiology S.M.NIAZARIFIN DepartmentofComputerScienceandEngineering (cid:2) (cid:2) UniversityofNotreDame IN,USA GREGORYR.MADEY DepartmentofComputerScienceandEngineering UniversityofNotreDame IN,USA FRANKH.COLLINS DepartmentofBiologicalSciences UniversityofNotreDame IN,USA (cid:2) (cid:2) TrimSize:156mmx234mm Arifi ffirs.tex V3-03/04/2016 3:23pm Pageiv Copyright©2016byJohnWiley&Sons,Inc.Allrightsreserved PublishedbyJohnWiley&Sons,Inc.,Hoboken,NewJersey PublishedsimultaneouslyinCanada Nopartofthispublicationmaybereproduced,storedinaretrievalsystem,ortransmittedinanyformorbyany means,electronic,mechanical,photocopying,recording,scanning,orotherwise,exceptaspermittedunder Section107or108ofthe1976UnitedStatesCopyrightAct,withouteitherthepriorwrittenpermissionofthe Publisher,orauthorizationthroughpaymentoftheappropriateper-copyfeetotheCopyrightClearanceCenter, Inc.,222RosewoodDrive,Danvers,MA01923,(978)750-8400,fax(978)750-4470,oronthewebat www.copyright.com.RequeststothePublisherforpermissionshouldbeaddressedtothePermissions Department,JohnWiley&Sons,Inc.,111RiverStreet,Hoboken,NJ07030,(201)748-6011,fax(201) 748-6008,oronlineathttp://www.wiley.com/go/permission. 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[DNLM:1.Malaria–epidemiology.2.ComputerSimulation.3.GeographicInformationSystems.4.Models, Theoretical.5.SpatialAnalysis.WC755.1] RA644.M2 614.5′32090285–dc23 2015033121 PrintedintheUnitedStatesofAmerica (cid:2) (cid:2) TrimSize:156mmx234mm Arifi ffirs.tex V3-03/04/2016 3:23pm Pagev Tomyparents: EngineerS.M.GolamMostofa B.Sc.Engg.(Civil),FIE(B),PGD(CS) MyFatherandGuide ProfessorParvinAkhterJahan M.A.(Economics),B.A.(Honors) MyMotherandBestFriend andmywife: RumanaReazArifin B.S.,M.S. MySoulmate andmysister: MafruhatulJannat Ph.D.,M.S.,B.S. WeGrewupTogether (cid:2) (cid:2) — S.M.NiazArifin (cid:2) (cid:2) TrimSize:156mmx234mm Arifi ffirs.tex V3-03/04/2016 3:23pm Pagevi (cid:2) (cid:2) (cid:2) (cid:2) TrimSize:156mmx234mm Arifi ftoc.tex V3-02/27/2016 9:02am Pagevii CONTENTS ListofContributors xv (cid:2) (cid:2) ListofFigures xvii ListofTables xxi Preface xxiii Acknowledgments xxix ListofAbbreviations xxxi 1 Introduction 1 1.1 Overview, 1 1.2 Malaria, 3 1.3 Agent-BasedModelingofMalaria, 4 1.4 Contributions, 4 1.5 Organization, 5 2 Malaria:ABriefHistory 7 2.1 Overview, 7 2.2 MalariainHumanHistory, 7 2.2.1 TheMalarialPath:AncientOrigins, 8 2.2.2 NamingandKeyDiscoveries, 9 2.2.3 AntimalarialDrugs, 9 2.2.4 PreventionMeasures, 10 (cid:2) (cid:2) TrimSize:156mmx234mm Arifi ftoc.tex V3-02/27/2016 9:02am Pageviii viii Contents 2.3 MalariaEpidemiology:AGlobalView, 10 2.3.1 TheMalariaParasite, 11 2.3.2 GeographicDistribution, 12 2.3.3 TypesofTransmission, 12 2.3.4 RiskMappingandForecasting, 13 2.4 MalariaControl, 13 3 Agent-BasedModelingandMalaria 17 3.1 Overview, 17 3.2 Agent-BasedModels(ABMs), 17 3.2.1 Agents, 18 3.2.2 Environment, 19 3.2.3 Rules, 20 3.2.4 SoftwareforABMs, 20 3.3 HistoryandApplications, 21 3.3.1 M&SOrganizations, 21 3.4 AdvantagesofABMs, 23 3.4.1 Emergence,Aggregation,andComplexity, 23 3.4.2 Heterogeneity, 24 3.4.3 LearningandAdaptation, 24 (cid:2) 3.4.4 FlexibilityinSystemDescription, 24 (cid:2) 3.4.5 InclusionofMultipleSpaces, 25 3.4.6 LimitationsofABMs, 25 3.4.7 ABMsvsMathematicalModels, 27 3.4.8 ApplicabilityofABMsforMalariaModeling, 28 3.5 MalariaModels:AReview, 29 3.5.1 MathematicalModelsofMalaria, 30 3.5.2 Agent-BasedModels(ABMs)ofMalaria, 33 3.5.3 TheSpatialDimensionofMalariaModels, 35 3.6 Summary, 36 4 TheBiologicalCoreModel 39 4.1 Overview, 39 4.1.1 RelevantTermsofInterest, 40 4.2 TheAquaticPhase, 41 4.2.1 Egg(E), 42 4.2.2 Larva(L), 43 4.2.3 Pupa(P), 45 4.3 TheAdultPhase, 46 4.3.1 ImmatureAdult(IA), 46 4.3.2 MateSeeking(MS), 47 4.3.3 BloodMealSeeking(BMS), 47 (cid:2)
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