i R E T H I N K I NG R E P ROGE N E T IC S ii iii Rethinking Reprogenetics Enhancing Ethical Analyses of Reprogenetic Technologies Inmaculada de Melo- Martín 1 iv 1 Oxford University Press is a department of the University of Oxford. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. Oxford is a registered trade mark of Oxford University Press in the UK and certain other countries. Published in the United States of America by Oxford University Press 198 Madison Avenue, New York, NY 10016, United States of America. © Oxford University Press 2017 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Oxford University Press, or as expressly permitted by law, by license, or under terms agreed with the appropriate reproduction rights organization. Inquiries concerning reproduction outside the scope of the above should be sent to the Rights Department, Oxford University Press, at the address above. You must not circulate this work in any other form and you must impose this same condition on any acquirer. Library of Congress Cataloging- in- Publication Data Names: de Melo- Martín, Inmaculada, author. Title: Rethinking reprogenetics : enhancing ethical analyses of reprogenetic technologies / by Inmaculada de Melo- Martín. Description: Oxford ; New York : Oxford University Press, [2017] | Includes bibliographical references. Identifiers: LCCN 2016013522| ISBN 9780190460204 (hardcover : alk. paper) | ISBN 9780190460228 (epub) | ISBN 9780190460211 (updf) Subjects: | MESH: Reproductive Techniques, Assisted— ethics | Genetic Enhancement—e thics Classification: LCC RG133.5 | NLM WQ 208 | DDC 176/ .2— dc23 LC record available at http://l ccn.loc.gov/2 016013522 1 3 5 7 9 8 6 4 2 Printed by Sheridan Books, Inc., United States of America v For Cristina, she is so much like her mom, her dad, and her brother vi vii CONTENTS Acknowledgments | ix 1. Introduction: Challenging Mainstream Defenses of Reprogenetic Technologies | 1 2. Reprogenetic Technologies: An Overview | 35 3. Procreative Liberty: The Moral Permissibility of Reprogenetics | 62 4. Conscripted in the Pursuit of Perfection: The Moral Obligation to use Reprogenetic Technologies | 97 5. The Illusion of Control: Reprogenetic Technologies and the Natural Lottery | 133 6. Not of Woman Born: Reprogenetics and the Erasing of Women | 160 7. Different Things Delight Different People: On the Value- Neutrality of Reprogenetic Technologies | 197 8. Enhancing the Assessment of Reprogenetic Technologies: The Case of Mitochondrial Replacement | 245 INDEX | 281 viii ix ACK NOW LEDGMEN TS This book has benefited from the comments of friends and col- leagues. Thanks are due to Stephen Brown, Ina Cholst, Sharon Crasnow, Malia Fullerton, Anita Ho, Kristen Intemann, Mary Mahowald, Laura Purdy, and Arleen Salles for their helpful sug- gestions and criticisms. Much of this work was done during my 2015 sabbatical leave. I am thankful to Weill Cornell Medical College for sab- batical funding and to my Division Chief, Joseph Fins, for his support. Thanks also to Zev Rosenwaks and Ron MacKenzie for their continuing support of my work. Part of my sabbatical leave was spent at the University of Washington. I am grateful to the UW Philosophy Department for inviting me to be the Benjamin Rabinowitz Visiting Professor in Medical Ethics. It was while I was there that this project took final shape. I am particularly grate- ful to Sara Goering, Michael Rosenthal, and Alison Wylie for all their help during my stay. Thanks are also due to the students in my class, Ethical Issues in Reproductive and Genetic Technologies. Our discussions helped me clarify many of the arguments that appear in this book. I am similarly indebted to Stephen Brown for pushing me to write this book and for offering me the space— literally and ix
Description: