Reading Primary Literature, A Practical Guide to Evaluating Research Articles in Biology PDF
Preview Reading Primary Literature, A Practical Guide to Evaluating Research Articles in Biology
ReadPirnigm Lairtye rature AP arctciaGlu itdoEe v aluRaetsienAagrr tcliheic snB iology ChristMo.Gp ihlelre n KenyCoonl lege PEARSON BPnj1a1i1 1 1 1 . (l llll ll l lll gs SaFnr anciBsocsot onw ork CapTeo wnH onKgo ngL ondona drid ·j O ity MontrMeuanli cPha riisn gapoyrd ny okoy Toroo nt r:l aAi]recx ander n, irt :u san· lWoiwn irtM : red rsa ndin kt iMnagn arLg:a uHraernp boroagha n upr viSshoarn:Tn oozni er n mn t,m posiatniIdoJ nl,u stBrlaaDtcoikto nGsr:o up turMiann raS:gt aWceeiyn bre rge in B:i ka DG rto up in : vn tnet Sht reeta nSMdta urdiPileoyrsnr y t odv rP rinCtoeurrW:ie te forr, d rP ht oR:i chMaergdn a/FunPdhaomteongtraalp hs R :S hinvtAahnia nDdraenUx neilv eCrhsriityBs,rt oiunUsens iarvrseofdiLa t Vyrne e LeI iB rwonG ourcC hoellMeigcehB,au erla tSopvriAircnbhgUo nri v,eC rytsnhiCityooa�Ti Garr;:;n tatU nirsvi Mtya,r Cyzae Lcohu rCdoelslD eagveDi,ad l IenkdeiU annisavi eDtraayMn, . 14 StaUtn ivtye,Mr iskGiee uBsozw lGirnegSe tnaU tnei veKrastMih.tyGy ,i lKlneeynnCo ogllee, RobGerrte sgoeLnry oCno llMeagrHeke, n Usn iveorNfso irCtyta hr oaltGir neabe onDrsoer,bah o HettiTnexgaLesur t hUenriavne Crisnidtyy, KJlaemMveaisdc ikUsinosin v eTrosKdiodtys ,t man UniveorfWiss ict)o n-Ossihnk JoasLnhei,w SiUsN GYe neJsaecoMk,ii lel eSrt aUOtnheii voe rsit}� BrSatidUt nhi verCsoiltyo -rDoaefdn ovL eor,u Wiosoet Gteoonr CgoiuaUrnnt ei rvsJietyn,n y DellaGpeioertCgroiouaU rnnt i ve(sr tsuidtyCe hnrtJi)os,htG neyo rCgoiuaUrnnte i rvs(sittyude nt) Copyri2g00h7Pt e©a rEsdounc aItnipcou.nb,,l iassPh eianrBgse onnjC aummimni1 n3g0s1, Saonm Set S.a,Fn r ancCiA9s 4c1oA1,l1r l.i ghtsM arneusfearicvtnteh uder. e SUdtn aoitefts e d AmerTihcpiaus.b liicpsar toitobenyCc otpeydra nipdge hrtm isshsobiueool nbd t afriothnmee d publpirisothraoe n rpy r ohirbeiptreodds utcotirianaro genet, r siyesvtoatrel rm a,n simanniy s sion forombr ya nmye aenlse,c tmreocnhiapcnh,io ctaolc,ro epcyoirondlrg ii,kn e.egT w,ooi bstain permiiosnst(uoss m)ea tefrroimta hwlio sr k, plaew arsiert etsqetuunPobe e mssaritoEt dnuc a �on. InPcre.m,ii osDnsesp maern1tt9,0E 0.L akAev eG.l,e nvILi6 e0w0F,2o 5ir.n m foarotrnieardin gg permissciao(ln8ls44 ,78 )6 -2635. Manyo ft hdees niagtuisobenydsma nfaucutrearnssd e ltldoei rssut iithsnehgpi orrudct ares! � ·. tr� mark.Whs eret heod sesaitgianopnpsie ntah rbi osoa knt,dh p eui bslrhw eaawsare oaf clathiedme ,s itginohanabsve epe rni inintn eidct aiopaarsll c la. p s ISB3N9:-7 I8 -08053-4599-5 ISBN0--1800:5 3-4599-X 171 61 5t 4 161 71 819 -CRW-coftl www.aw�bC· Contents Sect1iI:on nt rodtuotc hBt oiooknJ ct 1 WhaAtr Per imRwe)s>e Aarrtcihrc Jl es WhyR eatdhP er imLairtye ra2ture? Howt oU s1 T hBioso kl2et �ct2i:Fo inn dRiensge Aarrtcihc les Window-ShBoorpwpsiinngg: J3ournals NeedilnaHe a ystSaecakrc:hD iantga ba5ses SectiEoxne rc2i 6ses Sect3i:To hnAe n atoomfaPy a per 7 FormaMtattitneg7r s Citat8i on AuthToerhR se:s eaTrecahm9 PublicDaattiPeeosenR:r e vi1e0w Abstr1a2c t Acknowled1g3m ents Referenc1e3s TehE xtenRdeesde aTrecahm1 4 Sect3iE oxne rc1i4s es Sect4i:To hnIe n troduction UndersttahJnead rign1og5n ObservEaxtpiloannsExpa,et riionmntess1, 7 ScieansacC ey clPiorccaels1 s9 Sect4iE oxne rcises 20 Sect5i:To hnMe a terainMadel tsh ods PrelimWionraaknrA dyp prov1a ls Nutasn/ dJ olt'sr:i m1hle/ n 1ptri l_ J J �enp1d 1V 1 ariable� Indepewni d1 eh·'nlt Controalrl1ieI/ \d ConItsli2 I G p LJI TAERRYA TiUiRiE /frproducmiu/llJf ir/pietavt2 a4h ility Th/eJ Piigc thu:r\eJ:J eDreisn1i 1214e nta/ ,.: Corrd1eoS tthudli'easta:11 e1Cdro n1ne1(sn' s/2 i5o Corlrac't·•S,h tu1s:dC ihatlelwns'm u//, iimoisnt 25at CautshaS't<1'u /lJi1<e,11't1'G<H ,ro\u'1/:,J sri w 2i6w (' 01'1S<.t'wu ldlNiieelpsN:1M _etaesudIJr eef.{n.s \ 2i(j Modl�e \�vs2t6ems l!.:vafh{wttpienrRDi emsein2Rt7na / 'ec5t/ i!.,or�ncr ies es 28 ect6iT:oh nRe e sults 29 DealwiinVtgah r iaSbtialtiity2s:9t ics DescrSitpattiivCseet nitTcresan:ld aennVdca yr liiaty3b 0i InferSetnattiiaslta iS casm:pt loaFPe ro opmun l a3t1io StatiTsetsNitucsala:nll Ad l terHnyaptoitvhe3e 2ses PosiRteisvue3l 3t s NegaRteisvue3l 3t s BioloRgeilceavla3 n4c e VisualRiezsiuTnlagtb sal:neG dsr ap3h4s Grap3h5s EvaluDaatti3an6 g Sect6Ei xoenrc i3s7e s Sect7iT:oh Dnei sciuosn 3 InterpreFtiantdiMioennag:n i3n8g ConnecRteiloantsit:ooO n tshWoherirkp 3 9 ExplanaantIdim opnlsi c4a0tions Sect7Ei xoenr c4i0ses Sect8i:Po unt tIiAtnI gJo gether J Reusn s;fo rS t�undat nsJd -. dourcsat Wt,fHite,\ 42 Books� 1t iJc h/o Ru,tJ, i,aPu u pn, L�almRepe uwh It Ii• , � DJG PRI1 RY I 'II LRkI R Secnt1 i:Io ntrodutcott hiBeoo noe ktl mP·igr mp. aa rrpy·eeo srpeseaaa ndr rsot.c oi ahrcr am.wlent aee toyxsh c weeo rlrelolsefsdon c futiiofirs ercctrn eunets dtrs fe ce.boA 1ah '01 o y gsoRyb uee. ga m.d - ar�ded um asg tae r sh1tee·c 1s y1·c,fio1e wuc�nei tbtl1elhc T ohhdape.lu lrtepotono hftgsi hceebnird oksi o tkiailtscpeog apyti ulldo elyyuk y oornt,uw 1eh d g gr eho,u th�p1 rocIetds ess.c ntbhteeos o alnssd t ratyeoguni'eelestld o b egrienang d i articles. WHATA REP RIMARREYS EARACRHT ICLES? Primarreys eaarrtcihac llcseaosl ,rl eesde paarpcehor rps r imlairtye rature, arteho effi cidaolc umtehnsatctsi eunstteico s otmsm unicraetseet aetorah ccehhi r oth.Re erseapracphed ress corriibgefii nndailin ngcsl,u mdeitnhgog dyao nldo resuIlnct osn.td roacsutm,te hnsatytsn thseusmimzaeor,rei vzael,u atlei tprimary erataurtree er mseedc onsdoaurryCc oemsm.so enc onsdoaurriycn ecslm uadgea znea rtidcilcetsi,ot neaxrtibaeonsowd,ke sb,sM iatgeasz.wi rnieftsto ergn nt he i e erpaulb lsiucca,hsD iscoavnSedcr i enAtmiefiricpc uabnlo,in slshye condary artiScolmepesu .b licsautcaihsot nhsesc ,i ejnotuirnfiSaccl ise anncNdea ture. pubslha m ixtoufpr rei mraersye paarpceahrn ssde conrdeaproPyrr timsary. i papaerraesl wawyrsi tbtyse cni enwthiissletecs o,nr deaprmoyar byte ws r ibtyt en scisetnjsto,u rnoarlo itshteIsrnp,s r .a cytoiucn'eel,elt d ol ooakte acsho urce i caretfoud leltye rimifiit ns pe r imoarsr eyc onPdrairmysoa.ur ryic necsel au d detadielspectdri ooftn hm ee thaondrdse suTlhteasyrt. eh fi er rsetp oofor rtiin alg i resefianrdcihan ngadsr w er itbtyte hsnec iewnhtopi esrtfsdo t rhwmeoe rTkhi.s boofko cuosnpe rsi mraersye aarrtcihc les. . Youe' pvrobasbpleyhn otu rresna dgsi cietnecxeotk .b T ohY dsecn.eb accteespdc iefancttiasfinc cdo ncaenptdths ae,ry we r ittotweanar t due'ndta udi encIenc. o nttr,re asseaarrtciahcd lderaser seosafe s m erkgnionledwgg oerc ontro verasnytd,h eayrw er itwtietpnhr ofesssicoineaanlstt ihins ttesn aduedndi cee. Resehaa rrtcircelpersse sceineitnnp c reoss cw,eh itlete b odoekssbec �hre oiut comoeft hparto cReesasd.ri ensge aarrtcirhce lqeudsiiff reersse tn�rgt1a estt� an readtienxgt baonoydko swu,i e lnlc ounnetcweh ra llase ynogbueeg smr edaing theTmh.ib so okwliegltil yv oetu h teo otloose v rcotmhceeh eanlgsl.e PRIMALRIYT ERATlU RE READING WHYRE ADTHE PRIMARYL ITERT.CARE? Do m·sg ·c i1·esa np cwoeerfu l\ Vtaloye arni ffit. ., .r rat-O.....I ...Y.... . .., � . ., ta··tr 1e ct·· 1·s1t am ·s pcsn ta ·cohrt cw1 mabeyeegt ype n be .o r c frmmo_onei�ll rok O\ leYe eyd.xl .pethil. re _ u -_ eann� n_de_ rtm. np ·eh nei .· -eal .•...r,,._ _ rearshcea.i uC.....1e s1· a sc enlat critatoiyfp\ rtiac mg1 en-.tThink 1 ofr esearc aasd o o....t�rw m·a..0l y t.' h s ecn it.ei \fiVcoTh relvpd "'r. ne tht e ban. et .ao p ·pmat le aril yo,vu e1e amdet ohurgreh.a C:d.inot exkst, ab nooIdti e mtnolg e urec .tThe ·c allhenge eyxotauotm fo hpryial onleoukoswwr n in gst chs1 cwei.nane thtsti.n.emA s t )gntti dasefieth yecr n eo uhr _a·b goet e mco .sThn an..et _ 1-anah -zee neswc ieindteiafisc. Trtyoa pparcrohe adriensgea arrtciahcsa lc eh alelr eaenr �g anac o re. Whitlhpeemr airlyi tuermreaa aytp pderyau.rn dtheesr� ace ·ouill fi nddram a ancdo nvterrRoseysr.hec s aciecnotnisstftaasnmc �t et ! ·e nbeecas e t hv.:eo r at theed goefo uknro wleSdogr ee.s eartaircsclc hae nbe ·d eett eecin oe .in whiscchi ecnatriesgftaustlt hlhecyerl uaenesdy icdeen needteood ·e cinteifi probFluemrstl.hi eakgr eo, o dde tencotvithevelec o eo fc iceeonft ehasn enterttwaiiasnntsidsun rgp Friinsaetlshrl.eey s�e archr e·fl eupotcne rea ture scietnhteivmsestIsesdt.l o cumentthset iohropo lriwso .r iatnpidrae cst.ci hcanegse ovteiram nehd o twh ceoyo paenrcdao tmep �ei tteeha cohth eRre.c ogniztheepe r sonsaioldfs e c ieinwtci aeld;lud s ecfuoln tteotx hrteee aracrt icolure e ad. Learningt ore raeds eaarrtcihhca olsbe vsi boeunsei fifot usp ltapon uea resecaarricebnhei ro lBoutgthyb e.r ieexfp otstou hrpeeri ma·rtye raffaoturer ded byt hbioso kwlibelebtl e nefiecvieiyanfol n ue· earg arienaa p drim aryl itee ra artAisac lceh.i ludpt, h teIr utmaopnloedekt arn etdpo l ,ta hSetar ar The.m.e loeundo utgodh r iovuIerr iSsehtu tnedrte hrke i tctahbee .Hn o 'e veInr ve er became esskpielaclniIedca d al,tnpl lya any o tteo dYaeymt. b attilththe e trumcpoenttt ieonn uriemc yha dullibtfy ee n hanmcyai pnpgr teicaoinnuad dn er stdiannogfm usIintc h.se a mwea yl,e arningt o rperimaraydl ittuerorepea nth e dootro wacrodmsp rehaenneddav ilnugaa tliln gos foc rtsi iefincit normf tin . �am rteora eds he aarrtcaincydlo ewusi b lelc ommeo rcaeo ndnfieatdn e ffiti e - Judogfsec ieinntfiofirmc,a tai ornemseafrsukklaii blntllo ya d fu ord . HOWT OU STEH IBSO OKLET tbaL.oi c�e xaWpt�.nni.sia gdtt vud oh.r·itavao et fr nidpaioycP rvmd1eem ·ea iiary e sun, n ,ec t a r yx·rmem·geFp agert sowtt r ie·rlhocca y ·gla ahrto er tt ifiuxee cchsib'aae hl sae msta el ue ilhsysonthlnyaeo t ieg n ue lk daart efieey oBah nd.ocumtiog iloil i rn od betnlteru ha brcdnd·aro maeda· an nt sala di0 c° mk nnl eeeg w.o tn� 'a eky oau o mcpeetnatn grYl.oe 1un1'e etdoo os tabnytde h atrean dp rac- at.rtib1e 1ca .scebi , oat iht. mnoh g' osc ktantm· rasg una phcd nrt ,ea.ai c noaltdrani enec deeaefiidd hsn.0. gS o i its ithr aei.dn grese arch Thibso okiltse�h it n strmuacntuyiaoolunn ' eletldoq uicbkelcyoa mt ea lented reaodfre� ree aracrht iTchlseee sc.tc ioovnhesor wt ofi nadr titchslete rsu,oc fture reseaarrtcihc ltehfseo, um raa inpnda rotfas na rtitchIlene t:cr toidMouant,e rials an,dM ethoRdess,u alntdDs� s,c ussIinao dnd.i ttois otnu dtyhibinosgo klet, yo1u�a ls�eoe tdo s truwgigtrlhee s eaarrtcihyc oluersTs heeeln fd.- eocft-ison exercwiislpe·lrs o mt,ph. tpa tr actt.ih ceaeys;y ko tuo c riltyir ecaaapdl a rpb ey ap1yp m g·te hs ec.ts 1 dv0a �1ne D.e �pndm?gyn �u rc �orsaen idn sotrry,uom cuit ght c�hoe y ouorw na rtuiscmltgehm es tructsieocnt2osi ry o omnu i rn scttrmouirg ht assoingen. Asy obue gyionu jro urnienytt ohp er imlairtye roafbt iuoyrl,teo h gewriel l inebvlibyteo a bstaacnfldre uss trBauItth i oopyneos u. awlifislnolsd a taicstifinon overcgot mhciehn allaennpdga erst iciintp haet ipnorgfso ccieees.ns c Secti2o:Fn i ndRiensge Aarrtcihc les Thmea jjooru rnianbli so medniocpwiu nbelo inslihMn eo.rt eh aam ni llsciioiencfin t articlaerasev aifrleaoebn lt ehI en tearnnemdta ,nm yo rcea bnea ccefosrsa fe eed. Alownigtthi hsa vailcaobmicelhsia tlyl Secnigeennste.ie tsdofit nsrd e leivnanfto r matiaomni adm sotu ntoainfd aatnatd h iennt ellaingaeltnyhtzele y i nformation. This sectdieosnc ritbhfireess st t elpo:c aatniadnc gc esrseinsgea arrtcihTc hldeee stail.s wiblels pectioyfi ocui rn stiatnusdtu ibodni sscoiw pewl iiflnolec ,ou ngs e neral strateangdfri eeoesnli ndea tabYaossueh soa.ul llsdeo arn a botuhstep ecrieofisucr ces availaobnly eo ucra mpus. Thset ratyeogui eesm pldoeyp eonwntdi h lel puorfyp oousre sAeryaeor uc h. trytiodn egv eltooppf ioaacr researSccha npntaihptneeag rbo ?lfc e o ntoefan ts prestjioguirnomauilsg ghitvy eo suo me idecausrr ehanobrttoe uste aareras.c h You might atas lescoo nsdloaouroryskc u ecashst extbaonomdka sg azinfoer ideas. If ysoeul'evcet eadl rae aagrdeeybna ue,ntr e aetldofi ntartidoc pliec witthhitanot p tihcey,no mui gdhetc itods ee adractha boafrs eesse artia rlce.h Orp erhaps yofuo'uvanenid n atlerreaearsdttyii cnnlgoe nw e aetndord e aodm e relaatretdit copl uetsi nci otn tIentx hti.s ycoamusi egl,ho toa ktt he e it citaenasdl sseoa dractha bases. WINDWO-SHOPPBIRNOGW:S IJNOGU RNALS Suppyooswuei sthob rowjsoeu rntaodl esv etlp oiip d a . rhea ny uofi nd journaOlnsep? l aicyseo usrc holoilb'rwsah rhiy ,hh a.r dp ioef m anjoyu r nalHsa.v itnhpgea pjeoru rnianyl o uhra ndasnb parutliau re lfywu hle yno u arber owsfioinrng et setrtionpgiO cfos u.r ,ms a njyo urnaarlae lo a vaielabl onliIynfeo a.ul rekandowywh ijcohu rnyaowlua nttob roewa, impslter aitsegy tol ociattse howmietpahanI g net e,rne eatre cnhg iOnnel.ij noeu rnhaalvse straighitnftoerrtwfhaaaarcltdel y ouowt ob rowosree a rfcoahrr ticles. READIPNRGI MARLYI TERATEU 3R orAgnahoentr twih aze.Ftyemo oas �crxc a emspos1 e nI .myo e u Jw ·miofialunllimds tsa h nriyoma uprw gotehaJb. enos ttuiah rntlcamsat bl ..1t 0om s agae dnid- c.m ea tteh H .ih wgter pres,s s ei thoesdt byS tand.f oUrni.v Leirraribs.eis t y (ww.w.h 1.ge .howrtEgxrce)l.ln eti nrsutcntsfi oor. tuhssemi gat reae av illeaon bi st hamonbedrp oaYiwtgo shetucee. a1ae s ne0ef o 1i.acntes o t n sfJo·ot u rfnrae len'cscti h seossoouF.sneo mterah mnaJ.ayto t uclrnyhsaaoer,cueis csne tostrst ht ees maobsoratuye atecra e pfne�tu1�tp·i tl1buseld.i y aa c tr cintelo.Asir ueeusfqieusferal as u turboesft c hHrewii igptfrhthewsi aeiioci retncasese,la s aivn iasbgolltf ei J.uO m awlistfr hee o nle aicncess. . . Amlos1t00 0 s ·c t1Ie' Jnfio. cu mlaasr heo tesdo .nH 1ghwr.et H.o wc aynuo d e.dcei wh.i Jcoh.u 1 sma art eeh m osrteev lnatt oy our tWohpiicachrt? eeh m osrte iblael? Wh.i acerht h meot sPr e stoiug?·sO i. ne strat1·.ets gol y ok o1 nt·he r .�e e1necresset·nc rn o f yocu1ar s tesxt obok t osee w hicohu mJaalrcse.i ttehde;as rele i ykt. eo ble r eeavlnt tyoo cuoru e arnshdi grheglayr d·Ae s.d yboeug.t i ofin n .rd e sceharta ircesly,ou c na alcsehoc kt heRierfeen rceCsied t ecstioangsat;ih n.Je, o urnsta hlta� rrege uarlly ceidta er teh mosutesfu la npder stigJioouurnsra.ankil n gas lesxo.i O snetw iedly usmeeda es,tu hriem pafcatcm teoars,uh roewms a ntyi mtehsare t isc ulpbeslhdie inaj ournaarcleeid tb yo ther Fairnt,aiy lcollcuyea sn. ascko uyironstuserrto u rc orl ibrWairedliyaren a.da ncdi tjeodu rtnhaalptsu blriesshe ianrb cihog l)o inclSucdiee:Nn acteu,Cr eel,Dl ev,le opmeGnetn,e tPircosc,ne gesod fit he NatiAocnaadle omfSi ceise( nPcNeAJ So)u,r nBailo loofCg hiecmailJs oturyrna,l ofCl inIincvaels tJioguartonifEao xlnp ,e rimBeinoltAoamgley r,i Jcoaunrno afl PhysiNoeluorgJoyon,u, rn oafBl a tceiroloagnydP, u blic oLfiS bcricaeeryn (PLBoiSo)l Tohgiiyass.p arltiitsahtle;a r rmeea noyt her oujtosuatrnlasn.d ing Anoertu hsewfuebls iitsBe i oMCeedn t(rwaw.lwb iomedccoe)m.nw trhhai l . pubelsmi oserh tha1n5j 0o urnianlcsl,u gdeinnetgri atsllu ecashsB MCB io/oay anJdo uronfBa ilo laongsdyp ecitailtislzueecasdhsB MCP hylsgyoi aondR IC Mirocbiogyl.Ao rteispc ulbliisnh eBdi oMeda roCeep netnr-aamlceani cnecss, thtahtce yab ne fr eelayc ceasnsddei ds trYiobcuuan ts eedah.alr lco ft hBei, ol.de Cenrtajlorn ualorsb r wosep arctuaril tliets. Ymyummtaafihmrolaaoe� a s.Ir cseOStanu,yyua fiemau·aye tw t n c1tuer anrn1.pr ·sIpp1 . bhneuu1lo1sae 1c1 edtd sete pmcc. pli eeac aoicsn yl 1c k a.n i sy . aonia cs rhrtno� u n re etuspt sastthvtc , drtbs u hi.seaee eo 'oaah noin itPpattapa da ti 1 eani rnvee eece trhhimacl v·hr·1e· fub c ehntow nuleuae; gto Js n tt 1 ru sl·ere Ie . tte r y-i sasaoect 1snseurn h n a·npI txedel atuoo t si aa a s m·a.tetvac towtaaemn,.ldlAi,·tf v oth etie ia avsArcg l.l cl .uyahett rninidkl dwuyl bcy sori ot.aldxooo uimg -l ehuosli taog nia tfbnvitaghtet r nahr to tntp et ennP oet ha a betw ha ofrt Duhopr l ifoIaerb RuesFu svrteco'n rcu ttyerlif ]tdeeiic l r1 tod'si aclartoaitaho crn,tearm i ne :tsdfuo-it nreels te.wnfta i t oaelnchs steiid 1 oeuity.f;fcr hmr-lnrla Tr o oota tlb omsoF aate®ty p the eonnhu l\\ f.m1u rf spm h e rtuoaI· teo p a neae trrlht x eprna h tttttomdefeni mttvP nprtmrtstt hrte D p prdaonlrhe v·eec ,ehpF.e dhgtle·iar·rn isrn.r. s es crtib, d PYitn· "'ie in oee oet tsoo l ° 3c rnDlh o fFt ek t·hn ue -ee 4 REANDGIP RIMLAIRRATYTE URE tt<.svI..urt a .�p rst1mfn .��a'1y a mt urip, 0 oah-tsd .1ff.\ a't h rt 1 \ntcrr a .h to he...t amtf t t pmmnehovyu me1ri.r ob.fn l ssuoal ftot irnricyer.a.o ttsaor mr bnbihhnua aoyLy ecele ru.rtr o l od p tiic·eo diTogea pd kaachnsi ta siSetltceu.ni,p.onecr t h h asFn o aigo .hu c .l ·geuetp lrec nm· cxe nra da letk cv ·mt ttsecsn.arlapw n ba � eose· yIb n vn e'i uno be am· u c. d atuxle 1wtau b, ehte hnes d·lch 'ctd.ml hte m nt 1· c te -l 8o ava.i altma. ab nlm s.t 1ntsui,ats n1 o tthoetorhle a nta sby olute 1cto e n tstofyru cs tha1tta p artiacrut.l1 acrl e OLEI NA H AYSTASCEKA:R CHGID NAATBASSE uppoosu h av vedl opreeds etaao rpcaihncn de e dt ofi nrdele vapnrtai rym s.u r . rm ayyb ohua vfeo uans di njgoluera nrate alin cndlee dt ofi nadd Id_ ' ttaol�nt' l}c o nth. e �set opIinbc o.t h sceaasrecash e,seir anrgac rthei dcal-ta ba wibl la ne ffecatpipvreo Saecvhed.ra atla bmaasybe eas v laaieb olny our � pu; hoot hoen bee sstu ittoey do utro pAilct.h odeutgahiw livsla lry h0 htfrl y mo nteo ntehxett hg,ee neprrailn cwiipbllelte hssea em,a nmdo ts databan tahicen l pifnuslt rtuocg teyitoo sunt sa rted. A ane amwpel1'ed1 ,i sctuhfrsees e alvya iPlUaMBbE lDes i,wt hiicpsha rt e fa ni nrtc onnceocltleedoc fdt aitoanbo apseerbsay tt ehde NaCtnitrfoo nra l e e Biocth nolIongfyo rm(aNtCiBwoIwn,w .ncbi.nlPmU.BnMiEahDl. lgoowv ). u tro arcahr tiicnal lems5o ,s0tj0 o0u rinnma eldsi acnirdne el fiaetleIddns . total1 5mo ivlelri ona rciein tcaltGuiidovetnedhsn.he u gneu mrbo fc iitoaintn e PUBMEsDe paruasteiafnrugtl i frcolmae lsol ft he craebnse tt r iGcokody . earcwhi blecl o mprehmeenasntiihvnewegiy, rl elt aulorlrmn o sotfte hart ilec onap artitcoupalinacdr, awlibsleowl e llfomceuasnteihdne,gy turnw ialral r e e sonanbulmebo efar r tiwciltfeehwsi rrelaervtainctl es. Thceh oicsee aotrfec rhim ossb viocursultcyoai nae lff ecteiavrYeco huan. finde artcehr omnst hfier psatg oefr eseaarrtcihlc olofekosa r;I t io fnnts beltohwAe b stYroamuci tg.ah ltps iouc pku setfeurlim snse conoduarr ry b browgs ianrticSlcei etnoitftitulsesetnsess p . e ciwaolriwdzi eptdrh ei m _n ingssoi t haellstpooks n oswo moeft hsec ievnotciafibcFu olraa rmlyp ..w htle thgee nlep ruabslaiy"csh e art asa ctiteanctksi,as'"yut' d ndm aaryi da �t:� "mycoardiinafla r"chteifaoarnit,l ""u craer,id"si cahc''e mi,rna. t urlifiar b ln lat"iw ointe,ha cohft heep hrasesas ohnaw1vht iad nigrffin mt ani.n arg� usidnigff nettr eerwmisrl elt duirffne reetonsfat r 1t. is n. in actwlhh t tertmous s cea bned iffitcodu lrttm i,an n sdo mt rmi arllr mf Y O edd . Donb' atf rtaosi tdart sear athr imtn hgna i thw tbi ithmr tt .a rhc ar'e fre anfda satn,bd c rt ta sr ctrh m s ocf�atnnb la nd fr m th citotinas rt urbnyae ndi nisteiaarlc h. baBss ci eanucsslac unc idto tseinm staryuso sulvebla jreveidotcon c tuna fssb utIrlhnPs a UarBmycMe.oE, t nDp th, eme t anyed ra� met a- caleldt hM ediScuablcj tH adin(gMs H ).Y ouc afinn Mde SH wordYs REAIDNPGR IMARYL IETRATURE S
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