Quantitative Methods for HIV/AIDS Research PDF
Preview Quantitative Methods for HIV/AIDS Research
Quantitative Methods for HIV/AIDS Research Quantitative Methods for HIV/AIDS Research Edited by Cliburn Chan Michael G. Hudgens Shein-Chung Chow Covercredit:PeterHraber,ThomasB.Kepler,Hua-XinLiao,BartonF.Haynes. AdaptedfromLiaoetal.(2013)Nature496:469. CRCPress Taylor&FrancisGroup 6000BrokenSoundParkwayNW,Suite300 BocaRaton,FL33487-2742 ©2018byTaylor&FrancisGroup,LLC CRCPressisanimprintofTaylor&FrancisGroup,anInformabusiness NoclaimtooriginalU.S.Governmentworks Printedonacid-freepaper InternationalStandardBookNumber-13:978-1-4987-3423-3(Hardback) Thisbookcontainsinformationobtainedfromauthenticandhighlyregardedsources.Reasonableefforts havebeenmadetopublishreliabledataandinformation,buttheauthorandpublishercannotassume responsibilityforthevalidityofallmaterialsortheconsequencesoftheiruse.Theauthorsandpublishers haveattemptedtotracethecopyrightholdersofallmaterialreproducedinthispublicationandapologize tocopyrightholdersifpermissiontopublishinthisformhasnotbeenobtained.Ifanycopyrightmaterial hasnotbeenacknowledgedpleasewriteandletusknowsowemayrectifyinanyfuturereprint. ExceptaspermittedunderU.S.CopyrightLaw,nopartofthisbookmaybereprinted,reproduced, transmitted, orutilized in anyform by anyelectronic, mechanical, or othermeans, now knownor hereafterinvented,includingphotocopying,microfilming,andrecording,orinanyinformationstor- ageorretrievalsystem,withoutwrittenpermissionfromthepublishers. For permission to photocopy or use material electronically from this work, please access www. copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222RosewoodDrive,Danvers,MA01923,978-750-8400.CCCisanot-for-profitorganizationthatpro- videslicensesandregistrationforavarietyofusers.Fororganizationsthathavebeengrantedaphoto- copylicensebytheCCC,aseparatesystemofpaymenthasbeenarranged. TrademarkNotice:Productorcorporatenamesmaybetrademarksorregisteredtrademarks,andare usedonlyforidentificationandexplanationwithoutintenttoinfringe. LibraryofCongressCataloging-in-PublicationData Title:QuantitativemethodsforHIV/AIDSresearch/CliburnChan, MichaelG.Hudgens,Shein-ChungChow. Description:BocaRaton:Taylor&Francis,2017.|“ACRCtitle,partofthe Taylor&Francisimprint,amemberoftheTaylor&FrancisGroup,theacademic divisionofT&FInformaplc.”|Includesbibliographicalreferencesandindex. Identifiers:LCCN2017008215|ISBN9781498734233(hardback)| ISBN9781315120805(e-book) Subjects:LCSH:HIVinfections--Research--Methodology--Popularworks.|AIDS (Disease)--Research--Methodology--Popularworks. Classification:LCCRC606.64.Q362017|DDC616.97/920072--dc23LCrecord availableathttps://lccn.loc.gov/2017008215 VisittheTaylor&FrancisWebsiteat http://www.taylorandfrancis.com andtheCRCPressWebsiteat http://www.crcpress.com Contents Preface......................................................................................................................xi Contributors........................................................................................................xvii Section I Quantitative Methods for Clinical Trials and Epidemiology 1. Statistical Issues in HIV Non-Inferiority Trials......................................3 Mimi Kim 2. Sample Size for HIV-1 Vaccine Clinical Trials with Extremely Low Incidence Rate......................................................................................17 Shein-Chung Chow, Yuanyuan Kong, and Shih-Ting Chiu 3. Adaptive Clinical Trial Design.................................................................41 Shein-Chung Chow and Fuyu Song 4. Generalizing Evidence from HIV Trials Using Inverse Probability of Sampling Weights.............................................................63 Ashley L. Buchanan, Michael G. Hudgens, and Stephen R. Cole 5. Statistical Tests of Regularity among Groups with HIV Self-Test Data................................................................................................87 John Rice, Robert L. Strawderman, and Brent A. Johnson Section II Quantitative Methods for Analysis of Laboratory Assays 6. Estimating Partial Correlations between Logged HIV RNA Measurements Subject to Detection Limits..........................................109 Robert H. Lyles 7. Quantitative Methods and Bayesian Models for Flow Cytometry Analysis in HIV/AIDS Research.............................................................135 Lin Lin and Cliburn Chan 8. The Immunoglobulin Variable-Region Gene Repertoire and Its Analysis..................................................................................................157 Thomas B. Kepler and Kaitlin Sawatzki ix
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