Progress in Basic and Clinical Immunology PDF
Preview Progress in Basic and Clinical Immunology
PROGRESS IN BASIC AND CLINICAL IMMUNOLOGY ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan Recent Volumes in this Series Volume 486 PURINE AND PYRIMIDINE METABOLISM IN MAN X Edited by Esther Zoref-Shani and Oded Sperling Volume 487 NEUROPATHOLOGY AND GENETICS OF DEMENTIA Edited by Markus Tolnay and Alphonse Probst Volume 488 HEADSPACE ANALYSIS OF FOODS AND FLAVORS: Theory and Practice Edited by Russell L. Rouseff and Keith R. Cadwallader Volume 489 HEMOPHILIA CARE IN THE NEW MILLENNIUM Edited by Dougald M. Monroe, Ulla Hedner, Maureane R. Hoffman, Claude Negrier, Geoffrey F. Savidge, and Gilbert C. White II Volume 490 MECHANISMS OF LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION VIII Edited by Sudhir Gupta Volume 491 THE MOLECULAR IMMUNOLOGY OF COMPLEX CARBOHYDRATES-2 Edited by Albert M. Wu Volume 492 NUTRITION AND CANCER PREVENTION: New Insights into the Role of Phytochemicals Edited under the auspices of the American Institute for Cancer Research Volume 493 NEUROIMMUNE CIRCUITS, DRUGS OF ABUSE, AND INFECTIOUS DISEASES Edited by Herman Friedman, Thomas W. Klein, and John J. Madden Volume 494 THE NIDOVIRUSES (CORONAV IRUSES AND ARTERIVIRUSES) Edited by Ehud Lavi, Susan R. Weiss, and Susan T. Hingley Volume 495 PROGRESS IN BASIC AND CLINICAL IMMUNOLOGY Edited by Andrzej Mackiewicz, Madej Kurpisz, and Jan Zeromski A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher. PROGRESS IN BASIC AND CLINICAL IMMUNOLOGY Edited by Andrzej Mackiewicz University School 0/ Medical Sciences GreatPoland Cancer Center Poznan, Poland Maciej Kurpisz Institute 0/ Human Genetics Polish Academy 0/ Sciences Poznan, Poland and Ja n Zeromski University School 0/ Medical Sciences Department o/Immunology Poznan, Poland Springer Science+Business Media, LLC Library of Congress Cataloging-in-Publication Data Progress in basic and clinical immunology/edited by Andrzej Mackiewicz, Maciej Kurpisz, and Jan Zeromski. p. ; cm. - (Advances in experimental medicine and biology, ISSN 0065-2598; v. 495) "Proceedings of the 14th European Immunology Meeting (EFIS 2000) held September 23-27,2000, in Poznan, Poland"-T.p. verso. Includes bibliographical references and index. ISBN 978-1-4613-5194-8 ISBN 978-1-4615-0685-0 (eBook) DOI 10.1007/978-1-4615-0685-0 1. Immunology-Congresses. 2. Clinical immunology-Congresses. I. Mackiewicz, Andrzej. 11. Kurpisz, Maciej. III. Zeromski, Jan, 1938- IV. European Immunology Meeting (14th: 2000: Poznan, Poland) V. Series. [DNLM: I. Immunity, Cellular-Congresses. 2. Autoimmunity-Congresses. 3. Dendritic Cells-physiology-Congresses. 4. Receptors, Immunologic-Congresses. 5. T-Lymphocytes-physiology-Congresses. QW 568 P964 2001] QR180.3 .P76 2001 616.07'9-dc21 2001038777 Proceedings of the 14th European Immunology Meeting (EFIS 20(0), held September 23-27, 2000, in Poznan, Poland ISSN: 00652598 ISBN 978-1-4613-5194-8 ©2001 Springer Science+Business Media New York Originally published by Kluwer Academic I Plenum Publishers, New York in 2001 Softcover reprint ofthe hardcover 1st edition 2001 http://www.wkap.nl 10 9 8 7 6 5 4 3 2 1 A C.I.P. record for this book is available from the Library of Congress All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher Contributors Supporters • The State Committee for Scientific Research • Olympus Optical Polska Sp. z 0.0. Contributors • Association for Fight Against Cancer "Genes For Life" • Becton Dickinson • CARL ZEISS Sp. z 0.0. • GlaxoWellcome • GreatPoland Cancer Center • LOT - Polish Airlines • PPS Airpol Sp. Z 0.0. • Talex SA • The Leopold Kronenberg Foundation • University School of Medical Sciences - Poznan • Wielkopolski Bank Kredytowy - WBK S.A. Participants • Alexis Corporation • Nature Publishing Group • Preussen Electra Polska • SARSTEDT Sp. z 0.0. • Sigma Aldrich Sp. Z 0.0. v vi Contributors List of Exhibitors • Abott Laboratories Poland • ADIS International Ltd. • Becton Dickinson • Bellco Biomedica Polska Sp. Z 0.0. • Biker PTiO • Biocom Systems s.c. • Biomibo • Bio-RAD Laboratories GmbH, Prospecta Sp. Z 0.0. • Birkhauser Publishers • Caltag Laboratories Inc. • CARL ZEISS Sp. Z 0.0. • DAKO Polska Sp. Z 0.0. • Elsevier • EFIS 2003 • ICN Biomedicals, Inc. • Inter Medic Sp. z. 0.0 • KARGERAG • Kendro Sp. z.o.o. • Miltenyi Biotec GnbH. • MPW Med-instruments Sp. Pracy • Nature Publishing Group • Olympus Optical Polska Sp. z.o.o. • Oxford University Press • Polaton OBRI • R + D Systems Europe Ltd. • SARSTEDT Sp. z 0.0. • Science International • Schering-Plough Central Europe AG • Stem Cell Technologies • Wiley-Vch Verlags GmbH • Wisepress Ltd. Preface Progress in Basic and Clinical Immunology is a result of the 14th European Immunology Meeting - EFIS 2000 held in Poznan, Poland on 23- 27 September 2000. EFIS 2000 gathered over 1400 immunologists from all over the world. It was an exceptionally memorable meeting for a number of reasons: 1) it was held in the last year of the century and the millennium, thus provoking conclusions of past achievements of immunology and projections for the future; 2) it was held in Poland, a country that is a symbol of struggle for freedom for a large number of scientists originating from the "Eastern Bloc" countries and 3) EFIS celebrated its 25th anniversary at this occasion. The scientific program included: Key Note Lecture by Peter Krammer (Germany), 9 State-of-Art Lectures including Rolf M. Zinkernagel (Switzerland) - Nobel Prize Laureate - lecture entitled "Immunity 2000", 14 Meet an Expert Sessions, 80 Plenary Lectures and 47 Workshops. Altogether 875 communications were presented. The philosophy of the scientific program did not follow the usual routine of immunology meetings. Topics of the plenary sessions were selected on the basis of recent developments rather than historical background. On the other hand Workshops were designed on the basis of abstracts submitted. We invited 117 authors to submit their presentations for publication in Progress in Basic and Clinical Immunology - 62 were received and are included in this book. Most of the papers are related to the tumour immunology and immunotherapy that reflects a major focus of submitted abstracts for EFIS 2000. Of course, not all the very valuable communications could be included in the volume. However, we trust that the selection that we have offered will be at least in part Vll viii Preface representative of the meeting and will pave the way for further developments. Andrzej Mackiewicz Maciej Kurpisz Jan Zeromski Contents T-CELLS CD3-dependent regulation of early TCRn gene expression in mainstream aO and NKaO T cell development........... •••••••• ••• 5 Nicole Baur and Klaus Eichmann Molecular characterization of gut T cell precursors in euthymic and athymic mice..................................................... ..... ... 15 Florence Lambolez and Benedita Rocha CRTH2: marker for the detection of human Th2 and Te2 cells..... •••.•••••••••. •••••••••.••.•.•.. •••.•••••.•.•••••• •••••.••. •••.•.•• 2S Lorenzo Cosmi, Francesco Annunziato, Grazia Galli, Roberto Manetti, Enrico Maggi and Sergio Romagnani GILZ, a glucocorticoid hormone induced gene, modulates T lymphocytes activation and death through interaction with NF-kB.......... ........•...•........•..........••..................•••••. 31 Carlo Riccardi, Stefano Bruscoli, Emira Ayroldi, Massimiliano Agostini and Graziella Migliorati Tyrosine phosphorylation of PICOT and its translocation to the nucleus in response of human T cells to oxidative stress.............................................................. .............. 41 Yael Babichev and Noah Isakov ix x Contents IMMUNE RECEPTORS The molecular specificity of IgG-Fc interactions with Fey receptors ................................................................ 49 Yusuke Mimura, Rodolfo Ghirlando, Peter Sonderrnann, John Lund and Roy Jefferis Regulation of myeloid cell proliferation and survival by p75/A IRMl and CD33 surface receptors. .... ..... ...... ...... .... ..... 55 Maria Cristina Mingari, Chiara Vitale, Chiara Romagnani, Michela Falco and Lorenzo Moretta X-linked lymphoproliferative disease: the dark side of 2b4 function........................................................... ........ 63 Cristina Bottino, Silvia Parolini, Roberto Biassoni, Michela Falco, Luigi Notarangelo and Alessandro Moretta ANTIGEN PRESENTATION / DENDRITIC CELLS Role oftapasin in MHC class I antigen presentation in vivo............ 71 Natalio Garbi, Pamela Tan, Frank Momburg, Gunter J. Hiimmerling Regulation of transporters associated with antigen processing (TAPs) by nucleotide binding to, and hydrolysis by, Walker consensus sequences......................................................... 79 Loredana Saveanu and Peter M. Van Endert The AIR-J encoded class II transactivator (CIITA): the master coordinator of MHC class II gene expression and .. more..... .... ... 83 Roberto S. Accolla Major histocompatibility complex class II (MHC II) expression during development of human fetal brain and haemopoietic organs..................................................... ................... ... 93 Teresa Wierzba-Bobrowicz, Elzbieta Kosno-Kruszewska, Eliza Lewandowska, Waldemar Lechowicz, Bogna Schmidt-Sidor Interactions between dendritic cells...................................... .... 103 Stella C. Knight, Fiona Burke and Penelope A. Bedford
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