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Porth’s Essentials of Pathophysiology PDF

3647 Pages·2019·70.418 MB·English
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Vice President and Publisher: Julie K. Stegman Director of Nursing Content Publishing: Renee Gagliardi Senior Acquisitions Editor: Jonathan Joyce Director of Product Development: Jennifer K. Forestieri Senior Development Editor: Meredith L. Brittain Editorial Coordinator: Tim Rinehart Marketing Manager: Brittany Clements Editorial Assistant: Molly Kennedy Design Coordinator: Stephen Druding Art Director, Illustration: Jennifer Clements Production Project Manager: Joan Sinclair Manufacturing Coordinator: Karin Duffield Prepress Vendor: S4Carlisle Publishing Services Fifth Edition Copyright © 2020 Wolters Kluwer. Copyright © 2015 Wolters Kluwer. Copyright ©2011 Wolters Kluwer Health|Lippincott Williams & Wilkins. Copyright © 2007, 2004 by Lippincott Williams & Wilkins. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at [email protected], or via our website at shop.lww.com (products and services). 9 8 7 6 5 4 3 2 1 Printed in the United States of America Library of Congress Cataloging-in-Publication Data ISBN-13: 978-1-975107-19-2 | eISBN: 9781975107208 ISBN-10: 1-975107-19-5 Library of Congress Control Number: 2019911909 This work is provided “as is,” and the publisher disclaims any and all warranties, express or implied, including any warranties as to accuracy, comprehensiveness, or currency of the content of this work. This work is no substitute for individual patient assessment based upon healthcare professionals’ examination of each patient and consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data and other factors unique to the patient. The publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for any resulting diagnosis and treatments. Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information sheet (the manufacturer’s package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise, or from any reference to or use by any person of this work. shop.lww.com To my husband, Stephen Sr., and children—Richie, Robby, Stephen Jr., and Rachel—who always inspire me. To those pursuing or continuing a love for healthcare, with a special thanks for your dedication, compassion, and selflessness. Contributors Contributors to Essentials of Pathophysiology, Fourth Edition Jacqueline M. Akert, RNC, MSN, WHNP-BC Nurse Practitioner Women’s Health Aurora Health Care Waukesha, Wisconsin (Chapters 40, 41 with Patricia McCowen Mehring) Diane Book, MD Associate Professor, Neurology Co-Director Stroke & Neurovascular Program Froedtert Hospital & Medical College of Wisconsin Milwaukee, Wisconsin (Chapter 37) Freddy W. Cao, MD, PhD Clinical Associate Professor College of Nursing University of Wisconsin–Milwaukee Milwaukee, Wisconsin (Chapters 18, 34) Paula Cox-North, PhD, ARNP Clinical Assistant Professor Hepatitis & Liver Clinic Harborview Medical Center University of Washington School of Nursing Seattle, Washington (Chapters 29, 30) Herodotos Ellinas, MD, FAAP, FACP Assistant Professor Department of Anesthesiology Med–Anesthesia and PGY-1 Program Director Medical College of Wisconsin Milwaukee, Wisconsin (Chapters 11, 12, 13) Jason R. Faulhaber, MD Assistant Program Director, Fellowship in Infectious Diseases Division of Infectious Diseases, Carilion Clinic Assistant Professor, Virginia Tech, Carilion School of Medicine Adjunct Professor, Department of Biomedical Sciences, Jefferson College of Health Sciences Roanoke, Virginia (Chapters 15, 16) Anne M. Fink, RN, PhD Postdoctoral Research Associate College of Nursing University of Illinois–Chicago Chicago, Illinois (Chapters 19, 20 with Karen M. Vuckovic) Susan A. Fontana, PhD, APRN-BC Associate Professor and Family Nurse Practitioner College of Nursing University of Wisconsin–Milwaukee Milwaukee, Wisconsin (Chapter 38) Kathleen E. Gunta, MSN, RN, OCNS-C Clinical Nurse Specialist Aurora St. Luke’s Medical Center Milwaukee, Wisconsin (Chapter 43) Nathan A. Ledeboer, PhD, D(ABMM) Associate Professor of Pathology Medical College of Wisconsin Milwaukee, Wisconsin (Chapter 14) Kim Litwack, PhD, RN, FAAN, APNP Associate Dean for Academic Affairs Family Nurse Practitioner Advanced Pain Management University of Wisconsin–Milwaukee Milwaukee, Wisconsin (Chapter 35) Glenn Matfin, MSc (Oxon), MB, ChB, FACE, FACP, FRCP Medical Director International Diabetes Center Clinical Professor of Medicine University of Minnesota Minneapolis, Minnesota (Chapters 10, 31, 32, 33, 39) Patricia McCowen Mehring, RNC, MSN, WHNP Nurse Practitioner Women’s Health Milwaukee, Wisconsin (Chapters 40, 41 with Jacqueline M. Akert) Carrie J. Merkle, PhD, RN, FAAN Associate Professor College of Nursing The University of Arizona Tucson, Arizona (Chapters 1, 2, 3, 4, 7) Kathleen Mussatto, PhD, RN Nurse Scientist Herma Heart Center Children’s Hospital of Wisconsin Assistant Clinical Professor of Surgery Medical College of Wisconsin Milwaukee, Wisconsin (Chapter 19, Heart Disease in Infants and Children) Debra Bancroft Rizzo, RN, MSN, FNP-BC Nurse Practitioner Division of Rheumatology University of Michigan Ann Arbor, Michigan (Chapter 44) Jonathan Shoopman, MD Assistant Professor of Anesthesiology and Critical Care Medical College of Wisconsin Milwaukee, Wisconsin (Chapters 22, 23) Gladys Simandl, RN, PhD Professor Columbia College of Nursing Milwaukee, Wisconsin (Chapters 45, 46) Aoy Tomita-Mitchell, PhD Associate Professor Department of Surgery Children’s Research Institute Medical College of Wisconsin Milwaukee, Wisconsin (Chapters 5, 6) Karen M. Vuckovic, RN, PhD, ACNS-BC Assistant Clinical Professor College of Nursing University of Illinois–Chicago Chicago, Illinois (Chapters 19, 20 with Anne M. Fink) Jill M. Winters, RN, PhD, FAHA President and Dean Columbia College of Nursing Milwaukee, Wisconsin (Chapter 9) Contributors to Porth’s Pathophysiology, Tenth Edition Sawsan Abuhammad, PhD Assistant Professor, Maternal and Child Health Jordan University of Science and Technology Irbid, Jordan Chapter 42: Structure and Function of the Male Genitourinary System Maeghan Arnold, MNSc, APRN, AGACNP-BC Clinical Instructor Practice Department College of Nursing University of Arkansas for Medical Sciences Little Rock, Arkansas Chapter 20: Disorders of Hearing and Vestibular Function Michele R. Arwood, DNP, MSN, BSN, CNS-BC, NE-BC, CJCP System Director, Quality and Accreditation Baptist Memorial Health Care Corporation Memphis, Tennessee Chapter 8: Disorders of Fluid and Electrolyte and Acid Base Balance Chapter 29: Structure and Function of the Respiratory System Trina Barrett, DNP, RN, CNE, CCRN

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