Table Of ContentPHYTOCHEMISTRY
Volume 1
Fundamentals, Modern Techniques,
and Applications
PHYTOCHEMISTRY
Volume 1
Fundamentals, Modern Techniques,
and Applications
Edited by
Chukwuebuka Egbuna
Jonathan Chinenye Ifemeje, PhD
Stanley Chidi Udedi, PhD
Shashank Kumar, PhD
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Phytochemistry, Volume 1: Fundamentals, Modern Techniques, and Applications
International Standard Book Number-13: 978-1-77188-759-5 (Hardcover)
International Standard Book Number-13: 978-0-429-42622-3 (eBook)
Phytochemistry, 3-volume set
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International Standard Book Number-13: 978-0-429-42627-8 (eBook)
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Phytochemistry / edited by Chukwuebuka Egbuna, Jonathan Chinenye Ifemeje, PhD,
Stanley Chidi Udedi, PhD, Shashank Kumar, PhD.
Includes bibliographical references and index.
Contents: Volume 1. Fundamentals, modern techniques, and applications.
Issued in print and electronic formats.
ISBN 978-1-77188-759-5 (v. 1 : hardcover).--ISBN 978-0-429-42622-3 (v. 1 : PDF)
1. Botanical chemistry. I. Egbuna, Chukwuebuka, editor
QK861.P65 2019 572’.2 C2018-904824-7 C2018-904875-1
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ABOUT THE EDITORS
Chukwuebuka Egbuna
Chukwuebuka Egbuna is a chartered chemist, a chemical analyst, and an
academic researcher. He is a member of the Institute of Chartered Chemists
of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular
Biology (NSBMB), the Royal Society of Chemistry (RSC), United Kingdom,
and the Society of Quality Assurance (SQA), USA. He has been engaged in
a number of roles at New Divine Favor Pharmaceutical Industry Limited,
Akuzor Nkpor, Anambra State, Nigeria, and Chukwuemeka Odumegwu
Ojukwu University (COOU), Nigeria. He has attended series of conferences
and workshops and has collaboratively worked and published quite a number
of research articles in the domain of phytochemistry. He has edited books
with top publishers such as Springer Nature and Elsevier. He is a reviewer
and an editorial board member for various journals, including serving as a
website administrator for the Tropical Journal of Applied Natural Sciences
(TJANS), a journal of the faculty of Natural Sciences, COOU. His primary
research interests are in phytochemistry, food and medicinal chemistry,
analytical chemistry, and nutrition and toxicology. He obtained his BSc
and MSc degrees in biochemistry at Chukwuemeka Odumegwu Ojukwu
University.
Jonathan Chinenye Ifemeje, PhD
Jonathan Chinenye Ifemeje, PhD, is an Associate Professor in the Department
of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu
Ojukwu University, Nigeria. He obtained his PhD in applied biochemistry
from Nnamdi Azikiwe University, Awka, Nigeria, and his MSc degree in
nutrition and toxicology from the University of Port-Harcourt, Nigeria.
He has to his credits over 40 publications in both local and international
journals. Dr. Ifemeje is currently the Coordinator, Students Industrial
Work Experience Scheme (SIWES), COOU and has served as an external
examiner for various institutions. He is the Managing Editor of the Tropical
Journal of Applied Natural Sciences and is serving as a reviewer and an
editorial board member for various journals. He has worked extensively in
the area of phytochemistry, nutrition, and toxicology. He is a member of
vi About the Editors
various institutes, including the Institute of Chartered Chemists of Nigeria
(ICCON), the Nigerian Society of Biochemistry and Molecular Biology
(NSBMB), and Society of Quality Assurance (SQA).
Stanley Chidi Udedi, PhD
Stanley Udedi Chidi, PhD, is a Full Professor of Biochemistry at the Department
of Applied Biochemistry, Nnamdi Azikiwe University, (UNIZIK), Awka,
Nigeria. He has taught in various institutions, including Madonna University
Okija, Nigeria, and Anambra State University, which is now Chukwuemeka
Odumegwu Ojukwu University, Nigeria. He is currently the Dean of Student
Affairs at UNIZIK. He has worked extensively in the field of phytochemistry
and food and medicinal chemistry and has supervised many MSc and PhD
students. He is well published with over 50 publications, which have attracted
over 170 citations. He is well traveled and has attended a series of workshops
and conferences locally and internationally. He is a member of various
professional institutes, which includes the Institute of Chartered Chemists
of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular
Biology (NSBMB), the Nutrition Society of Nigeria, and others. He obtained
his PhD and MSc degrees from UNIZIK, Nigeria.
Shashank Kumar, PhD
Shashank Kumar, PhD, is working as Assistant Professor at the Center for
Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda,
India. He obtained his BSc, MSc, and PhD Biochemistry from the Department
of Biochemistry, University of Allahabad, India. He worked as Postdoctoral
Fellow at the Department of Biochemistry, King George’s Medical University,
Lucknow, India. Dr. Kumar has about 60 published scientific papers/reviews/
editorial articles/book chapters in various national and international peer-
reviewed journals and has been cited more than 1200 times. He has edited
several books on topics such as the “concepts in cell signaling,” “carbohydrate
metabolism: theory and practical approach,” and so forth. He has expertise
in the areas of free radical biology, cancer biology, characterization of plant
natural products, xenobiotic metabolism, and microbiology. He is familiar
with many biochemical techniques such as spectrophotometry, enzyme-linked
immunosorbent assay, electrophoresis, polymerase chain reaction, real-time
polymerase chain reaction, flow cytometry, thin-layer chromatography,
high-performance liquid chromatography, liquid chromatography–mass
spectrometry, cell culture, and microbiological techniques. He has presented
About the Editors vii
his research findings at more than 25 national/international conferences and
attended about 30 workshops at different universities and medical colleges
throughout the India. Dr. Kumar is a life time member of Italo-Latin American
Society of Ethnomedicine, and the Indian Sciences Congress Association, and
member of the Asian Council of Science Editors, Dubai, UAE, and Publication
Integrity and Ethics, London. He has been awarded the Junior/Senior and
Research Associate Fellowships formulated and funded by various Indian
agencies, such as Indian Council of Medical Research, University Grants
Commission, Council of Scientific and Industrial Research India. Dr. Kumar
laboratory has been funded by the University Grant Commission, India, and
the Department of Science and Technology, India, for working on effects of
various phytochemicals on cancer cell signaling pathway inhibition.
CONTENTS
Contributors ................................................................................................xiii
Abbreviations .............................................................................................xvii
Foreword .....................................................................................................xxi
Preface ......................................................................................................xxiii
PART I: Fundamentals of Phytochemistry .............................................1
1. Introduction to Phytochemistry .....................................................................3
Chukwuebuka Egbuna, Jonathan C. Ifemeje, Toskë L. Kryeziu,
Minakshi Mukherjee, Hameed Shah, G. M. Narasimha Rao,
Laurence John Francis J. Gido, and Habibu Tijjani
2. Biosynthesis of Phytochemicals ...................................................................37
Habibu Tijjani, Chukwuebuka Egbuna, and Luka D. Carrol
3. Mechanisms of Plant Defense Against Pathogens:
Phytoalexins Induction .................................................................................79
Hanan M. AL-Yousef and Musarat Amina
4. Biological Roles of Phytochemicals ...........................................................119
Peculiar Feenna Onyekere, Chioma Obianuju Peculiar-Onyekere,
Helen Ogechukwu Udodeme, Daniel Okwudili Nnamani, and
Christopher Obodike Ezugwu
5. Phytochemicals as Immunomodulators ....................................................153
Behnaz Aslanipour
6. Phytochemicals as Nutraceuticals and Pharmafoods ..............................179
Anywar Godwin
7. Role of Phytochemistry in Plant Classification:
Phytochemotaxonomy .................................................................................197
Felix Ifeanyi Nwafor and Ifeoma Celestina Orabueze
8. Plant Metabolomics ....................................................................................223
Sagar Satish Datir and Rakesh Mohan Jha
