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Perspectives on the Department of Defense Global Emerging Infections: Surveillance and Response System, A Program Review PDF

215 Pages·2001·1.16 MB·English
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Perspectives on the Department of Defense Global Emerging Infections Surveillance and Response System A Program Review Philip S. Brachman, Heather C. O’Maonaigh, and Richard N. Miller, Editors Committee to Review the Department of Defense Global Emerging Infections Surveillance and Response System Medical Follow-Up Agency INSTITUTE OF MEDICINE NATIONAL ACADEMY PRESS Washington, D.C. NATIONAL ACADEMY PRESS • 2101 Constitution Avenue, N.W. • Washington, DC 20418 NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance. Support for this project was provided by Contract No. DAM17-00-P-0412. The views presented in this report are those of the Institute of Medicine Committee to Review the Department of Defense Global Emerging Infections Surveillance Response System and are not necessarily those of the funding agencies. International Standard Book Number 0-309-07635-8 Additional copies of this report are available for sale from the National Academy Press, 2101 Constitution Avenue, N.W., Box 285, Washington, DC 20055. Call (800) 624-6242 or (202) 334-3313 (in the Washington metropolitan area), or visit the NAP’s home page at www.nap.edu. The full text of this report is available at www.nap.edu. For more information about the Institute of Medicine, visit the IOM home page at: www.iom.edu. Copyright 2001 by the National Academy of Sciences. All rights reserved. Printed in the United States of America. The serpent has been a symbol of long life, healing, and knowledge among almost all cultures and religions since the beginning of recorded history. The serpent adopted as a logotype by the Institute of Medicine is a relief carving from ancient Greece, now held by the Staatliche Museen in Berlin. “Knowing is not enough; we must apply. Willing is not enough; we must do.” —Goethe INSTITUTE OF MEDICINE Shaping the Future for Health National Academy of Sciences National Academy of Engineering Institute of Medicine National Research Council The National Academy of Sciences is a private, nonprofit, self-perpetuating soci- ety of distinguished scholars engaged in scientific and engineering research, dedi- cated to the furtherance of science and technology and to their use for the general welfare. Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that requires it to advise the federal government on scientific and technical matters. Dr. Bruce M. Alberts is president of the National Academy of Sciences. The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers. It is autonomous in its administration and in the selection of its mem- bers, sharing with the National Academy of Sciences the responsibility for advis- ing the federal government. The National Academy of Engineering also sponsors engineering programs aimed at meeting national needs, encourages education and research, and recognizes the superior achievements of engineers. Dr. Wm. A. Wulf is president of the National Academy of Engineering. The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public. The Institute acts under the responsibility given to the National Academy of Sciences by its congressional charter to be an adviser to the federal government and, upon its own initiative, to identify issues of medical care, research, and education. Dr. Kenneth I. Shine is president of the Institute of Medicine. The National Research Council was organized by the National Academy of Sci- ences in 1916 to associate the broad community of science and technology with the Academy’s purposes of furthering knowledge and advising the federal gov- ernment. Functioning in accordance with general policies determined by the Academy, the Council has become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in pro- viding services to the government, the public, and the scientific and engineering communities. The Council is administered jointly by both Academies and the Institute of Medicine. Dr. Bruce M. Alberts and Dr. Wm. A. Wulf are chairman and vice chairman, respectively, of the National Research Council. COMMITTEE TO REVIEW THE DEPARTMENT OF DEFENSE GLOBAL EMERGING INFECTIONS SURVEILLANCE AND RESPONSE SYSTEM PHILIP S. BRACHMAN (Chair), Professor, Department of International Health, Rollins School of Public Health, Emory University, Atlanta, Georgia RUTH L. BERKELMAN, Professor, Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia DONALD S. BURKE, Professor, Department of International Health and Director of the Center for Immunization Research, Johns Hopkins School of Public Health, Baltimore, Maryland KATHLEEN F. GENSHEIMER, State Epidemiologist, Bureau of Health, Maine Department of Human Services, Augusta, Maine C. JAMES HOSPEDALES, Director, Caribbean Epidemiology Center, Pan American Health Organization, World Health Organization, Port of Spain, Trinidad, West Indies ANN MARIE KIMBALL, Professor, Health Services and Epidemiology, Adjunct in Medicine, University of Washington, Seattle, Washington GUÉNAËL R. RODIER, Director, Department of Communicable Disease Surveillance and Response, World Health Organization, Geneva, Switzerland RONALD K. ST. JOHN, Executive Director, Center for Emergency Preparedness and Response, Health Canada, Ottawa, Ontario, Canada Project Staff RICHARD N. MILLER, Study Director HEATHER C. O’MAONAIGH, Program Officer PAMELA RAMEY-McCRAY, Administrative Assistant ANDREA COHEN, Financial Associate v Preface The U.S. Department of Defense (DoD) has historically defined its interest in infectious diseases almost exclusively in terms of “battle- stopper” illnesses—those resulting in acute effects that can directly affect military operations. Although this approach remains central to the U.S. military’s infectious disease doctrine, development of the DoD Global Emerging Infections Surveillance and Response System (GEIS) is part of an important transition in the way that the threat of infectious diseases— and, more specifically, the threat of emerging infectious diseases—is per- ceived and addressed by the U.S. military. Emerging infectious disease surveillance is sustained globally through a network of activities maintained through the collective efforts of numer- ous governmental and nongovernmental agencies. It is through the con- tributions of many partners that surveillance for emerging infectious diseases is possible. The DoD possesses valuable resources that can be brought to bear in this effort. It maintains an extensive, diverse array of laboratory facilities, both within the United States and overseas. These DoD laboratories can perform routine diagnostic testing, but they also possess rare, sometimes unique, diagnostic capabilities. DoD overseas laboratories are located throughout the world in areas where the potential for the emergence of infectious diseases is high. Often, laboratories oper- ate in regions where alternative laboratory resources are sparse or nonex- istent (e.g., sub-Saharan Africa). No other organization or government in the world maintains such extensive or capable laboratory facilities and staffing internationally. DoD laboratory facilities represent medical re- vii viii PREFACE search, public health, and diplomatic resources that serve U.S. military, U.S. civilian, and global interests alike. For more than a decade, formal DoD participation in emerging infec- tious disease surveillance has been encouraged by many in the U.S. public health community and within the DoD. In 1996, Presidential Decision Directive NSTC-7 (NSTC is the National Science and Technology Council of the Executive Office of the President) transformed these recommenda- tions into a mandate. Thereafter, the National Intelligence Council de- clared emerging infectious diseases to be a threat to the national security of the United States, underscoring the importance of DoD participation in disease surveillance efforts. This role is not an altogether new one, as the DoD has been conducting various infectious disease surveillance projects (e.g., for influenza) for many years. Accommodation of its expanded role has led the DoD to implement GEIS. The committee recognizes this effort as a responsive and effective step toward addressing the problem of emerging infectious diseases. We would like to thank the staff of the DoD laboratories, both domes- tic and overseas, and the staff of the GEIS Central Hub for the time and effort that they have invested in sharing with us information about the GEIS operations that they support. This review effort was very much a collegial one, and the report benefited from the openness of all those who provided us with documentation, presentations, and conversations. This study was also enriched by the insights that GEIS collaborators and asso- ciates provided regarding their views of GEIS from the outside looking in. Lists of the laboratory staff and GEIS collaborators and associates who shared their time with the committee can be found at the ends of Chapters 2 through 7 of this report. Any omissions are strictly the result of over- sight. The support provided by Institute of Medicine staff was instrumental in keeping this study moving apace. We extend our thanks to Richard Miller, Heather O’Maonaigh, and Pamela Ramey-McCray of the Institute of Medicine’s Medical Follow-Up Agency and to National Academies Travel staff, particularly Ann-Marie Walko, for their assistance. This study also benefited from the attention of Andrea Cohen, financial associate; Michael Hayes, consulting editor; and Linda Kilroy, contracting officer. Medical Follow-Up Agency staff members Phillip Bailey, Salem Fisseha, Lois Joellenbeck, and Karen Kazmerzak also helped along the way. In addition, we are grateful to GEIS Central Hub staff members, par- ticularly Joel Gaydos, Steve Gubenia, Patrick Kelley, Jennifer Rubenstein, and James Writer for their tireless assistance in preparing and compiling background documents and for helping to plan and negotiate the logistics of site visits. Likewise, we offer special thanks to Roxana Lescano, Lucy Rubio, and Trueman Sharp, Naval Medical Research Center Detachment, PREFACE ix Peru; Andrew Corwin and John Sisson, Naval Medical Research Unit 2, Indonesia; Gaye Ruble, Armed Forces Research Institute of Medical Sci- ences, Thailand; Cole Church, Naval Medical Research Unit 3, Egypt; Ronald Rosenberg, U.S. Army Medical Research Unit, Kenya; and Leslie Henry, Naval Health Research Center, San Diego, for their help in putting site visits together. This report is a testament to the hard work, patience, and resolve of many. We extend to all involved our appreciation and gratitude. Philip S. Brachman (Committee Chair) Ruth L. Berkelman Donald S. Burke Kathleen F. Gensheimer C. James Hospedales Ann Marie Kimball Guénaël R. Rodier Ronald K. St. John

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