Optimizing Patient Selection in Stereotactic Ablative Radiotherapy for Early Stage NSCLC through ...

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Optimizing Patient Selection in Stereotactic Ablative Radiotherapy for Early Stage
NSCLC through Comparative Effectiveness Research
Louie, A.V.
2016
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citation for published version (APA)
Louie, A. V. (2016). Optimizing Patient Selection in Stereotactic Ablative Radiotherapy for Early Stage NSCLC
through Comparative Effectiveness Research. [PhD-Thesis – Research external, graduation internal, Vrije
Universiteit Amsterdam].
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Download date: 15. Feb. 2023
Optimizing Patient Selection in
Stereotactic Ablative Radiotherapy for
Early Stage NSCLC through Comparative
Effectiveness Research

Alexander Vincent Louie
Optimizing Patient Selection in Stereotactic Ablative Radiotherapy for
Early Stage NSCLC through Comparative Effectiveness Research

Nederlandse title:
Betere selectie van patiënten voor SABR voor vroege stadia NSCLC door
comparative effectivness research
Thesis, Vrije Universiteit Amsterdam

© Alexander Vincent Louie, Amsterdam 2016
All rights reserved. No part of this book may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical,
photocopying, recording, or otherwise, without the prior written permission of the
copyright owner.

ISBN 978-0-9951930-0-0

Address for Correspondence:
Dr. Alex Louie
790 Commissioners Rd E, Room A3-807
London Health Science Centre
London, Ontario, Canada
N6A 4L6
email: [email protected]
2
VRIJE UNIVERSITEIT

Optimizing Patient Selection in Stereotactic Ablative Radiotherapy for Early Stage
NSCLC through Comparative Effectiveness Research

ACADEMISCH PROEFSCHRIFT

ter verkrijging van de graad Doctor aan
de Vrije Universiteit Amsterdam,
op gezag van de rector magnificus
prof.dr. V. Subramaniam,
in het openbaar te verdedigen
ten overstaan van de promotiecommissie
van de Faculteit der Geneeskunde
op donderdag 30 juni 2016 om 13.45 uur
in de aula van de universiteit,
De Boelelaan 1105

door

Alexander Vincent Louie

geboren te Mississauga, Canada
3
promotoren: prof.dr. S. Senan
prof.dr. B. J. Slotman

4
For my family
5
CONTENTS

Chapter 1 Introduction 9

ORIGINAL MANUSCRIPTS

Chapter 2 Withholding stereotactic radiotherapy in elderly 20
patients with stage I non-small cell lung cancer
and co-existing COPD is not justified: Outcomes
of a markov model analysis

Radiotherapy and Oncology 2012 May;99(2):161-5.
doi: 10.1016/j.radonc.2011.04.005

Chapter 3 When is a biopsy-proven diagnosis necessary before 39
stereotactic ablative radiotherapy for lung cancer?
A decision analysis

Chest 2014 Oct;146(4):1021-8.
doi: 10.1378/chest. 13-2924.

Chapter 4 Stereotactic ablative radiation therapy for 61
subcentimeter lung tumors: clinical, dosimetric,
and image guidance considerations.

International Journal of Radiation Oncology, Biology, Physics
2014 Nov 15;90(4):843-9

doi: 10.1016/j.irjobp.2014.06.064.

Chapter 5 Second primary lung cancers following a 81
diagnosis of primary head and neck cancer.

Lung Cancer. 2015 Apr;88(1)94-9.

doi: 10.1016/j.lungcan.2015.01.011.

Chapter 6 Treatment and survival of second primary 100
early-stage lung cancer, following treatment
of head and neck cancer in the Netherlands

Lung Cancer. 2016 Apr;94:54-60.
doi: 10.1016/j.lungcan.2016.01.022

Chapter 7 Measuring the population impact of introducing 122
Stereotactic ablative radiotherapy for stage I
non-small cell lung cancer in Canada.

The Oncologist 2014 Aug;19(8)880-5.

doi: 10.1634/theoncologist.2013-0469.

6
Chapter 8 Stereotactic body radiotherapy versus surgery for 142
medically operable stage I non-small cell lung
cancer: A Markov model-based decision analysis

International Journal of Radiation Oncology, Biology, Physics 2011 Nov 15;
81(4):964-73. doi: 10.1016/j.ijrobp.2010.06.040.

Chapter 9 Quality of life after stereotactic ablative radiotherapy 167
for early stage lung cancer: a systematic review

Clinical Lung Cancer 2015
doi: 10.1016/j.cllc.2015.12.009

Chapter 10 Patient reported outcomes following stereotactic 187
ablative radiotherapy or surgery for stage IA
non-small-cell lung cancer: Results from the ROSEL
multicenter randomized trial.

Radiotherapy and Oncology 2015;117(1)44-8.
doi: 10.1016/j.radonc.2015.08.011

Chapter 11 Predicting overall survival after stereotactic 201
ablative radiation therapy in early-stage lung cancer:
development and external validation of the
Amsterdam prognostic model

International Journal of Radiation Oncology, Biology, Physics
2015 May 9; pii: 30360-3016(16)00503-9.

doi: 10.1016/j.irjobp.2015.05.003 [Epub ahead of print]

Chapter 12 Stereotactic ablative radiotherapy versus lobectomy 223
for operable stage I non-small-cell lung cancer: a
pooled analysis of two randomized trials.

Lancet Oncology 2015;Jun;16(6):630-7.
doi: 10.1016/S1470-2045(15)70168-3.

Chapter 13 Stereotactic ablative radiotherapy and surgery: Two 245
gold standards for early-stage non-small cell lung
cancer?

Annals of Translational Medicine 2015 Jun;3(9):113.
doi: 10.3978.j.issn.2305-5839.2015.05.08

Chapter 14 Management of early-stage non-small cell lung cancer 254
using stereotactic ablative radiotherapy: Controversies,
insights, and changing horizons

Radiotherapy and Oncology, 2015 Feb;114(2):138-47.
doi: 10.1016/j.radonc.2014.11.036.

Chapter 15 Evaluations of health economics in radiation oncology: 289
A systematic review

International Journal of Radiation Oncology, Biology, Physics

2016 Apr 1;94(5):1006-14.
doi: 10.1016/j.ijrobp.2015.12.359.
7
LETTERS

Chapter 16 In response to Puri et al. 321

International Journal of Radiation Oncology, Biology, Physics
2012 Feb 1;82(2):523
doi: 10.1016/j.irjobp.2011.05.077

Chapter 17 Surgery versus SABR for NSCLC 324

Lancet Oncology 2013 Nov;14(12):e491.
doi: 10.1016/S1470-2045(13)70446-7.

Chapter 18 Computed tomography surveillance of patients with 328
resected lung cancer: Recurrence or second primary
lung cancer?

Journal of Thoracic and Cardiovascular Surgery 2014 May;147(5):1715.
doi: 10.1016/j.jtcvs.2014.01.002.

Chapter 19 Treatment for high-risk patients with early-stage 331
non-small-cell lung cancer

Journal of Clinical Oncology 2015 Feb 1;33(4)377.
doi: 10.1200/JCO.2014.58.1314.

Chapter 20 Defining the role of radiofrequency ablation and 335
stereotactic ablative radiotherapy for high-risk
early stage non-small cell lung cancer

Cancer 2015 Sep 30

doi: 10.1002/cncr/29698.

Chapter 21 Future Directions 339

Summary 358

Samenvatting 363

Acknowledgements 368

Curriculum Vitae 371

List of Publications 373

Abbreviations 382

8
Chapter 1

Introduction

9