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Oncology Board Review, Second Edition: Blueprint Study Guide and Q&A PDF

496 Pages·2017·8.54 MB·English
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Oncology Board Review Oncology Board Review Blueprint Study Guide and Q&A Second Edition Editors Francis P. Worden, MD Clinical Professor of Medicine Director of Hematology/Oncology Fellowship Program Division of Hematology/Oncology, Department of Internal Medicine University of Michigan Medical School Ann Arbor, Michigan Rami N. Khoriaty, MD Assistant Professor Division of Hematology/Oncology, Department of Internal Medicine University of Michigan Medical School Ann Arbor, Michigan Erin F. Cobain, MD Clinical Lecturer Division of Hematology/Oncology, Department of Internal Medicine University of Michigan Medical School Ann Arbor, Michigan Alexander T. Pearson, MD, PhD Clinical Lecturer Division of Hematology/Oncology, Department of Internal Medicine University of Michigan Medical School Ann Arbor, Michigan Visit our website at www.demosmedical.com ISBN: 9781620701157 e-book ISBN: 9781617052927 Acquisitions Editor: David D’Addona Compositor: Exeter Premedia Services Private Ltd. Copyright © 2018 Springer Publishing Company. Demos Medical Publishing is an imprint of Springer Publishing Company, LLC. All rights reserved. This book is protected by copyright. No part of it may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher. Medicine is an ever-changing science. Research and clinical experience are continually expanding our knowledge, in particular our understanding of proper treatment and drug therapy. The authors, editors, and publisher have made every effort to ensure that all information in this book is in accordance with the state of knowledge at the time of production of the book. Nevertheless, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the contents of the publication. Every reader should examine carefully the package inserts accompanying each drug and should carefully check whether the dosage schedules mentioned therein or the contraindications stated by the manufacturer differ from the statements made in this book. Such examination is particularly important with drugs that are either rarely used or have been newly released on the market. Library of Congress Cataloging-in-Publication Data Names: Worden, Francis P., editor. | Khoriaty, Rami N., editor. | Cobain, Erin F., editor. | Pearson, Alexander T., editor. Title: Oncology board review: blueprint study guide and Q&A / [edited by] Francis P. Worden, Rami N. Khoriaty, Erin F. Cobain, Alexander T. Pearson. Other titles: Oncology boards flash review. Description: Second edition. | New York: Demos, [2017] | Preceded by Oncology boards flash review / Francis P. Worden, Rami N. Khoriaty, editors. c2013. | Includes index. Identifiers: LCCN 2016056062 | ISBN 9781620701157 | ISBN 9781617052927 (e-book) Subjects: | MESH: Neoplasms | Examination Questions | Handbooks Classification: LCC RC266.5 | NLM QZ 18.2 | DDC 616.99/40076—dc23 LC record available at https://lccn.loc.gov/2016056062 Contact us to receive discount rates on bulk purchases. We can also customize our books to meet your needs. For more information please contact: [email protected] Printed in the United States of America by McNaughton & Gunn. 16 17 18 19 20 / 5 4 3 2 1 Contents Contributors Preface Acknowledgments Share Oncology Board Review: Blueprint Study Guide and Q&A, Second Edition PART I. HEMATOLOGIC MALIGNANCIES 1. Acute Leukemias and Hairy Cell Leukemia Lyndsey N. Runaas, Rami N. Khoriaty, and Dale Bixby 2. Chronic Lymphocytic Leukemia Erlene K. Seymour, Rami N. Khoriaty, and Dale Bixby 3. Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Brittany Siontis and Rami N. Khoriaty 4. Myelodysplastic Syndromes Rami N. Khoriaty and Dale Bixby 5. Hodgkin Lymphoma Darren King and Ryan A. Wilcox 6. Non-Hodgkin Lymphoma—Low Grade Erlene K. Seymour and Tycel J. Phillips 7. Non-Hodgkin Lymphoma—High Grade Erlene K. Seymour and Tycel J. Phillips 8. Peripheral T-Cell Lymphomas Sumana Devata and Ryan A. Wilcox 9. Multiple Myeloma and Plasma Cell Dyscrasias Maryann Shango and Erica Campagnaro PART II. AERODIGESTIVE MALIGNANCIES 10. Non–Small Cell Lung Cancer Manali Bhave and Gregory P. Kalemkerian 11. Small Cell Lung Cancer Dana E. Angelini and Khaled A. Hassan 12. Malignant Pleural Mesothelioma Jordan K. Schaefer and Gregory P. Kalemkerian 13. Thymoma and Thymic Carcinoma Jordan K. Schaefer and Gregory P. Kalemkerian 14. Head and Neck Cancers and Salivary Gland Tumors Paul L. Swiecicki and Francis P. Worden PART III. ENDOCRINE MALIGNANCIES 15. Thyroid Cancer Paul L. Swiecicki and Megan R. Haymart 16. Adrenocortical Carcinoma Frank C. Cackowski and Tobias Else 17. Pheochromocytomas and Paragangliomas Frank C. Cackowski and Tobias Else PART IV. BREAST CANCER 18. Breast Cancer Kunal C. Kadakia, Erin F. Cobain, and Monika Burness PART V. GENITOURINARY MALIGNANCIES 19. Bladder Cancer Sarah Yentz, Alon Weizer, and Ajjai Alva 20. Prostate Cancer Zachery R. Reichert, Megan E. V. Caram, and Kathleen Ann Cooney 21. Testicular Cancer Zachery R. Reichert and David C. Smith 22. Renal Cell Carcinoma Benjamin Y. Scheier and Bruce Redman PART VI. GASTROINTESTINAL MALIGNANCIES 23. Esophageal Cancer Raymond M. Esper, Paul L. Swiecicki, and James A. Hayman 24. Gastric Cancer David B. Zhen and Mark M. Zalupski 25. Colorectal Cancer Maryann Shango and John C. Krauss 26. Anal Cancer Maryann Shango and John C. Krauss 27. Pancreatic and Biliary Cancers David B. Zhen and Mark M. Zalupski 28. Hepatocellular Carcinoma Paul M. Corsello and Neehar D. Parikh 29. Neuroendocrine Tumors Sarah Yentz and Vaibhav Sahai PART VII. SARCOMA 30. Sarcoma Elizabeth J. Davis and Rashmi Chugh PART VIII. MELANOMA 31. Melanoma Darren King and Christopher Lao PART IX. CENTRAL NERVOUS SYSTEM MALIGNANCIES 32. Central Nervous System Tumors Erin F. Cobain, Aaron Mammoser, and Larry Junck PART X. GYNECOLOGIC MALIGNANCIES 33. Cervical, Vulvar, and Vaginal Cancers Kari E. Hacker and Karen McLean 34. Ovarian Cancer Lan G. Coffman and Ronald J. Buckanovich 35. Endometrial Cancer Lan G. Coffman and Ronald J. Buckanovich PART XI. CANCER OF UNKNOWN PRIMARY 36. Cancer of Unknown Primary Benjamin Y. Scheier and Laurence H. Baker PART XII. GENETICS AND TUMOR BIOLOGY 37. Genetics and Tumor Biology Carlos J. Gallego, Jessica N. Everett, Shawna Kraft, and Elena M. Stoffel PART XIII. SUPPORTIVE AND PALLIATIVE CARE 38. Oncologic Emergencies and Supportive Care Angel Qin, Francis P. Worden, and Maria Silveira PART XIV. BONE MARROW TRANSPLANTATION 39. Bone Marrow Transplant Lyndsey N. Runaas and Mary Mansour Riwes PART XV. BIOSTATISTICS 40. Biostatistics Alexander T. Pearson and Emily Bellile Index Contributors Ajjai Alva, MBBS, Assistant Professor, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Dana E. Angelini, MD, Associate Staff, Department of Hematology and Medical Oncology, Cleveland Clinic–Taussig Cancer Center, Cleveland, Ohio Laurence H. Baker, DO, Collegiate Professor, Cancer Developmental Therapeutics, Professor of Internal Medicine and Pharmacology, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Emily Bellile, MS, Statistician, Center for Cancer Biostatistics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan Manali Bhave, MD, Hematology and Oncology Fellow, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Dale Bixby, MD, PhD, Clinical Associate Professor, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Ronald J. Buckanovich, MD, PhD, Associate Professor, Internal Medicine, Division of Medical Oncology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan Monika Burness, MD, Clinical Lecturer, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Frank C. Cackowski, MD, PhD, Hematology and Oncology Fellow, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Erica Campagnaro, MD, Associate Professor, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Megan E. V. Caram, MD, MSc, Clinical Lecturer, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School; Staff Physician, Department of Medicine, Ann Arbor Veterans Affairs, Ann Arbor, Michigan Rashmi Chugh, MD, Associate Professor, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Erin F. Cobain, MD, Clinical Lecturer, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Lan G. Coffman, MD, PhD, Clinical Lecturer, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Kathleen Ann Cooney, MD, H.A. and Edna Benning Presidential Endowed Chair and Department Chair, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah Paul M. Corsello, MD, Gastroenterology Fellow, Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Elizabeth J. Davis, MD, Assistant Professor of Medicine, Division of Hematology/Oncology, Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee Sumana Devata, MD, Clinical Assistant Professor, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Tobias Else, MD, Assistant Professor, Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Raymond M. Esper, MD, PhD, Physician, Florida Cancer Specialists and Research Institute, Fort Myers, Florida Jessica N. Everett, MS, CGC, Clinical Assistant Professor, Department of Internal Medicine, Molecular Medicine and Genetics, University of Michigan Medical School, Ann Arbor, Michigan Carlos J. Gallego, MD, MS, Assistant Professor, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio Kari E. Hacker, MD, PhD, Gynecologic Oncology Fellow, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan Khaled A. Hassan, MD, MS, Assistant Professor, Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan

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Oncology Board Review: Blueprint Study Guide and Q&A is a concise, outline-based study guide covering the topics that appear on the Medical Oncology Certification Exam. This second edition has been thoroughly revised to include new treatment regimens, clinical guidelines, and other updates impacting
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