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On the Study and Practice of Intravenous Anaesthesia PDF

287 Pages·2000·15.97 MB·English
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ON THE STUDY AND PRACTICE OF INTRAVENOUS ANAESTHESIA ON THE STUDY AND PRACTICE OF INTRAVENOUS ANAESTHESIA Edited by JaapVuyk Leiden University Medical Center, Leiden, The Netherlands Frank Engbers Leiden University Medical Center, Leiden, The Netherlands and Sandra Groen-Mulder Leyenburg Hospital, The Hague, The Netherlands Springer-Science+Business Media, B.V. A C.I.P. Catalogue record for this book is available from the Library of Congress. ISBN 978-90-481-5366-4 ISBN 978-94-015-9604-6 (eBook) DOI 10.1007/978-94-015-9604-6 Printed on acid-free paper Layout: Bon Mot, Rotterdam All Rights Reserved © 2000 Springer Science+Business Media Dordrecht Originally published by Kluwer Academic Publishers in 2000. Softcover reprint of the hardcover 1s t edition 2000 No part of the material protected by this copyright notice may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording or by any information storage and retrieval system, without written permission from the copyright owner. ontents List of contributors ix Preface Xlll MODElLING OF ANAESTHETIC ACTION: THE EFFECT SITE Physiological modelling and the effect site 3 Michael Weiss - Halle-Wittenberg, Germany Targeting the effect site 17 james G. Bovill - Leiden, The Netherlands Effect sites of intravenous anaesthetic agents 27 Koji Morita, Tomiei Kazama, Shigehito Sato and Kazuyuki Ikeda - Hamamatsu, japan Exploring the plasma-effect site concentration difference 45 during effect site controlled infusion Catherine Moiny, Edouard Coussaert and Luc Barvais - Brussels, Belgium Genetic models and mapping genes in the study of 59 anaesthetic action Victoria j. Simpson, Brad Rikke, Elaine Shen, Beth Bennett, Yuri Blednov and Thomas johnson - Denver and Boulder Colorado, USA THE PERIOPERATIVE USE OF HYPNOTIC AGENTS Total intravenous anaesthesia: the equipment 71 Frank H.M. Engbers - Leiden, The Netherlands Closed loop control of general anaesthesia 89 Anthony Absolom and Gavin N. C. Kenny - Glasgow, United Kingdom The effect of opioids on the pharmacokinetics and 99 pharmacodynamics of propofol jaap Vuyk - Leiden, The Netherlands Strategies to prevent awareness 113 Michel Struys, Eric Mortier and Linda Versichelen - Gent, Belgium Patient controlled sedation during locoregional anaesthesia 129 Nick Sutcliffe and Daniel Amutike - Glasgow, United Kingdom Target controlled sedation in the intensive care unit 145 Sandra M. Groen-Mulder - The Hague, The Netherlands STATE OF THE ART ON NEUROMUSCULAR BLOCKADE Computer-controlled infusion of neuromuscular blocking 159 agents Valerie Billard and Philippe Mavoungou - Paris, France New neuromuscular blocking agents and fast-tracking 173 anaesthesia Hermann Mellinghoff - K61n, Germany Neuromuscular blocking agents in the elderly 187 Frederique Servin - Paris, France leu The use of neuromuscular blocking agents in the 195 Karin 5. Khanl-Brady - Innsbruck, Austria Neuromuscular blocking agents and neuromuscular 207 diseases BenoIt Plaud and Franr;ois Donati - Villejuif, France / Montreal, Canada vi OPIOIDS FOR PERIOPERATIVE PAIN RELIEF Sites of respiratory action of opioids 219 Elise Sarton and Albert Dahan - Leiden, The Netherlands Remifentanil - a new age in anaesthesia? 229 Johan Raeder - Oslo, Norway Monitored anaesthesia care with remifentanil 241 }. Robert Sneyd and Aileen Craig - Plymouth, United Kingdom Remifentanil anaesthesia and postoperative pain 249 management Stefan Schraag - Ulm, Germany Target controlled infusion for postoperative analgesia 261 Marjolein e.0. van den Nieuwenhuyzen - Leiden, The Netherlands Serotonin: its implications in postoperative nausea and 275 vomiting Alain Borgeat - Zurich, Switzerland vii List of contributors A. Absalom University Department of Anaesthesia Glasgow Royal Infirmary 10 Alexandra Parade, Glasgow G31 2ER, UK D. Amutike HCI International Medical Centre Bearmore Street Clydebank, Glasgow G81 4HX, UK L. Barvais Department of Anesthesiology Erasme University Hospital 808 route de Lennik, B-l070 Brussels, Belgium B. Bennett Departments of Anesthesiology and Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262 And Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA V. Billard Department of Anaesthesiology Institut Gustave Roussy; 94805 Villejuif, France Y. Blednov Departments of Anesthesiology and Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262 And Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA A. Borgeat Orthopedic University Clinic, Balgrist / Zurich Forchstrasse 340, CH -8008 Zurich, Switzerland J. G. Bovill Leiden University Medical Center Albinusdreef 2, 2300 RC, Leiden, The Netherlands E. Coussaert Department of Anesthesiology Erasme University Hospital 808 route de Lennik, B-1070 Brussels, Belgium A. Craig University of Plymouth/Derriford Hospital Plymouth Derriford Road, Plymouth, PL6 8DH, UK ix List of contributors A. Dahan Leiden University Medical Center Albinusdreef 2, 2300 RC, Leiden, The Netherlands C. Diefenbach Dept. of Anesthesiology & Intensive Care University Hospital Cologne 0-50924 Koln, Germany F. Donati Departement d'anesthesie - reanimation de I'universite de Montreal Campus Hotel Dieu 3840 rue Saint-Urbain Montreal, Quebec, Canada H2W 1T 8 F.H.M. Engbers Leiden University Medical Center Albinusdreef 2, 2300 RC, Leiden, The Netherlands S.M. Groen-Mulder Leyenburgh Hospital The Hague, The Netherlands K. Ikeda Surgical Center, University Hospital of Hamamatsu 3600 Handa, Hamamatsu 431-3192, Japan T. Johnson Departments of Anesthesiology and Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262 And Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA T. Kazama Surgical Center, University Hospital of Hamamatsu 3600 Handa, Hamamatsu 431-3192, Japan G.N.C. Kenny University Department of Anaesthesia Glasgow Royal Infirmary 10 Alexandra Parade, Glasgow G31 2ER, UK K.5. Khunl-Brady Department of Anaesthesia and Intensive Care Medicine The Leopold-Franzens-University of Innsbruck, Anichstrasse 35 A-6020 Innsbruck, Austria P. Mavoungou Department of Anaesthesiology Clinique Mutualiste, Nantes, France. x List of contributors H. Mellinghoff Dept. of Anesthesiology & Intensive Care University Hospital Cologne D-50924 Kbln, Germany K. Morita Surgical Center, University Hospital of Hamamatsu 3600 Handa, Hamamatsu 431-3192, Japan C Moiny Department of Anesthesiology Erasme University Hospital 808 route de Lennik, B-l070 Brussels, Belgium E. Mortier Department of Anaesthesia University Hospital of Gent De Pintelaan 185, 9000 Gent, Belgium M. van den Nieuwenhuyzen Leiden University Medical Center Albinusdreef 2, 2300 RC, Leiden, The Netherlands B. Plaud Departement d'anesthesie - reanimation Institut Gustave Roussy 39 rue Camille Desmoulins 94800 Villejuif, France J.C Reeder, Department of Anaesthesia Ullevaal University Hospital N-0407 Oslo, Norway B. Rikke Departments of Anesthesiology and Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262 And Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA E. Sarton Leiden University Medical Center Albinusdreef 2, 2300 RC, Leiden, The Netherlands S. Sato Surgical Center, University Hospital of Hamamatsu 3600 Handa, Hamamatsu 431-3192, Japan xi

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close circle of anaesthetic scientists but, with the help of computer technology, has greatly influenced the practice of the modern clinical anaesthesiologist. The efforts of anaesthesiologists, pharmaceutical companies, and the development of the internet has lead to a situation that now almost eve
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