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Nutritional sciences from fundamentals to food PDF

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Dietary Reference Intakes (DRI) The Dietary Reference Intakes (DRI) include two sets of values that serve as goals for nutrient intake—Recommended Dietary Allowances (RDA) and Adequate Intakes (AI). The RDA refl ect the average daily amount of a nutrient considered adequate to meet the needs of most healthy people. If there is insuffi cient evidence to determine an RDA, an AI is set. The DRI include a set of values called Tolerable Upper Intake Levels (UL). The UL represent the maximum amount of a nutrient that appears safe for most healthy people to consume on a regular basis. Turn the page for a listing of the UL for selected vitamins and minerals and the AMDR values for macronutrient intake. Estimated Energy Requirements (EER), Recommended Dietary Allowances (RDA), and Adequate Intakes (AI) for Water, Energy, and the Macronutrients Age (yr) Refere(nkcge /Bm2M)I Referecncme (ihnei)ght, Referekncg e( lwb)eight, WateraAI (L/day)EnergyEERb(kcal/dCaary)bohRyDdrA a(tge/daTy)otal fiAbI e(rg/day)Total faAtI (g/day)LinoleicA I a(cigd/day)LinoleniAIc (agci/dd cay)ProteinRDA (g/daPyr)doteinRDA (g/kg/day) Males 0–0.5 — 62 (24) 6 (13) 0.7e 570 60 — 31 4.4 0.5 9.1 1.52 0.5–1 — 71 (28) 9 (20) 0.8f 743 95 — 30 4.6 0.5 11 1.2 1–3g — 86 (34) 12 (27) 1.3 1046 130 19 — 7 0.7 13 1.05 4–8g 15.3 115 (45) 20 (44) 1.7 1742 130 25 — 10 0.9 19 0.95 9–13 17.2 144 (57) 36 (79) 2.4 2279 130 31 — 12 1.2 34 0.95 14–18 20.5 174 (68) 61 (134) 3.3 3152h 130 38 — 16 1.6 52 0.85 19–30 22.5 177 (70) 70 (154) 3.7 3067h 130 38 — 17 1.6 56 0.8 31–50 3.7 3067h 130 38 — 17 1.6 56 0.8 (cid:2)50 3.7 3067h 130 30 — 14 1.6 56 0.8 Females 0–0.5 — 62 (24) 6 (13) 0.7e 520 60 — 31 4.4 0.5 9.1 1.52 0.5–1 — 71 (28) 9 (20) 0.8f 676 95 — 30 4.6 0.5 11 1.2 1–3g — 86 (34) 12 (27) 1.3 992 130 19 — 7 0.7 13 1.05 4–8g 15.3 115 (45) 20 (44) 1.7 1642 130 25 — 10 0.9 19 0.95 9–13 17.4 144 (57) 37 (81) 2.1 2071 130 26 — 10 1.0 34 0.95 14–18 20.4 163 (64) 54 (119) 2.3 2368 130 26 — 11 1.1 46 0.85 19–30 21.5 163 (64) 57 (126) 2.7 2403i 130 25 — 12 1.1 46 0.8 31–50 2.7 2403i 130 25 — 12 1.1 46 0.8 (cid:2)50 2.7 2403i 130 21 — 11 1.1 46 0.8 Pregnancy 1st trimester 3.0 (cid:3)0 175 28 — 13 1.4 (cid:3)25 1.1 2nd trimester 3.0 (cid:3)340 175 28 — 13 1.4 (cid:3)25 1.1 3rd trimester 3.0 (cid:3)452 175 28 — 13 1.4 (cid:3)25 1.1 Lactation 1st 6 months 3.8 (cid:3)330 210 29 — 13 1.3 (cid:3)25 1.3 2nd 6 months 3.8 (cid:3)400 210 29 — 13 1.3 (cid:3)25 1.3 NOTE: For all nutrients, values for infants are AI. Dashes indicate that values have not been cThe linolenic acid referred to in this table and text is the omega-3 fatty acid known as determined. alpha-linolenic acid. aThe water AI includes drinking water, water in beverages, and water in foods; in general, dThe values listed are based on reference body weights. drinking water and other beverages contribute about 70 to 80 percent, and foods, the eAssumed to be from human milk. remainder. Conversion factors: 1 L (cid:1) 33.8 fl uid oz; 1 L (cid:1) 1.06 qt; 1 cup (cid:1) 8 fl uid oz. fAssumed to be from human milk and complementary foods and beverages. This includes bThe Estimated Energy Requirement (EER) represents the average dietary energy intake that approximately 0.6 L (~3 cups) as total fl uid including formula, juices, and drinking water. will maintain energy balance in a healthy person of a given sex, age, weight, height, and gFor energy, the age groups for young children are 1–2 years and 3–8 years. physical activity level. The values listed are based on an “active” person at the reference hFor males, subtract 10 kcalories per day for each year of age above 19. height and weight and at the midpoint ages for each group until age 19. Chapter 2 and Ap- iFor females, subtract 7 kcalories per day for each year of age above 19. pendix B provide equations and tables to determine Estimated Energy Requirements. SOURCE: Adapted from the Dietary Reference Intakes series, National Academies Press. Copyright 1997, 1998, 2000, 2001, 2002, 2004, 2005, by the National Academy of Sciences. Recommended Dietary Allowances (RDA) and Adequate Intakes (AI) for Vitamins d Age (yr) ThiamiRnDA (mg/dRaiyb)o flaRviDnA (mg/daNiya)cinRDA (mg/dBaiyo)atinAI((cid:5)g/day)PantotAhIe(nimc ga/cdiayV)itamiRn DBA (6mg/dFaoyl)ateRDA (µg/daViyt)bamiRn DBA (µ12g/daCy)holinAeI (mg/day)VitamiRn DCA (mg/dVaity)amiRn DAA (µg/daVyi)tcamiAnI (µDg/day)dVitamiRn DEA (mg/dVaiyt)eamiAnI (Kµg/day) Infants 0–0.5 0.2 0.3 2 5 1.7 0.1 65 0.4 125 40 400 5 4 2.0 0.5–1 0.3 0.4 4 6 1.8 0.3 80 0.5 150 50 500 5 5 2.5 Children 1–3 0.5 0.5 6 8 2 0.5 150 0.9 200 15 300 5 6 30 4–8 0.6 0.6 8 12 3 0.6 200 1.2 250 25 400 5 7 55 Males 9–13 0.9 0.9 12 20 4 1.0 300 1.8 375 45 600 5 11 60 14–18 1.2 1.3 16 25 5 1.3 400 2.4 550 75 900 5 15 75 19–30 1.2 1.3 16 30 5 1.3 400 2.4 550 90 900 5 15 120 31–50 1.2 1.3 16 30 5 1.3 400 2.4 550 90 900 5 15 120 51–70 1.2 1.3 16 30 5 1.7 400 2.4 550 90 900 10 15 120 (cid:2)70 1.2 1.3 16 30 5 1.7 400 2.4 550 90 900 15 15 120 Females 9–13 0.9 0.9 12 20 4 1.0 300 1.8 375 45 600 5 11 60 14–18 1.0 1.0 14 25 5 1.2 400 2.4 400 65 700 5 15 75 19–30 1.1 1.1 14 30 5 1.3 400 2.4 425 75 700 5 15 90 31–50 1.1 1.1 14 30 5 1.3 400 2.4 425 75 700 5 15 90 51–70 1.1 1.1 14 30 5 1.5 400 2.4 425 75 700 10 15 90 (cid:2)70 1.1 1.1 14 30 5 1.5 400 2.4 425 75 700 15 15 90 Pregnancy ≤18 1.4 1.4 18 30 6 1.9 600 2.6 450 80 750 5 15 75 19–30 1.4 1.4 18 30 6 1.9 600 2.6 450 85 770 5 15 90 31–50 1.4 1.4 18 30 6 1.9 600 2.6 450 85 770 5 15 90 Lactation ≤18 1.4 1.6 17 35 7 2.0 500 2.8 550 115 1200 5 19 75 19–30 1.4 1.6 17 35 7 2.0 500 2.8 550 120 1300 5 19 90 31–50 1.4 1.6 17 35 7 2.0 500 2.8 550 120 1300 5 19 90 NOTE: For all nutrients, values for infants are AI. cVitamin A recommendations are expressed as retinol activity equivalents (RAE). aNiacin recommendations are expressed as niacin equivalents (NE), except for recommendations for dVitamin D recommendations are expressed as cholecalciferol. infants younger than 6 months, which are expressed as preformed niacin. eVitamin E recommendations are expressed as (cid:4)-tocopherol. bFolate recommendations are expressed as dietary folate equivalents (DFE). Recommended Dietary Allowances (RDA) and Adequate Intakes (AI) for Minerals Age (yr) SodiumAI (mg/dayC)hloriAdIe (mg/dayP)otassiAIu (mmg/dayC)alciuAmI (mg/dayP)hosphRoDrAu s(mg/daMya)gneRsiDuA m(mg/Idraoy)nRDA (mg/dZianyc)RDA (mg/Idoadyi)neRDA (µg/dSayel)eniRuDmA (µg/daCyo)pperRDA (µg/daMya)ngaAIn e(semg/daFyl)uoridAeI (mg/dayC)hromiAIu (µmg/day)MolybRdeDnA u(µmg/day) Infants 0–0.5 120 180 400 210 100 30 0.27 2 110 15 200 0.003 0.01 0.2 2 0.5–1 370 570 700 270 275 75 11 3 130 20 220 0.6 0.5 5.5 3 Children 1–3 1000 1500 3000 500 460 80 7 3 90 20 340 1.2 0.7 11 17 4–8 1200 1900 3800 800 500 130 10 5 90 30 440 1.5 1.0 15 22 Males 9–13 1500 2300 4500 1300 1250 240 8 8 120 40 700 1.9 2 25 34 14–18 1500 2300 4700 1300 1250 410 11 11 150 55 890 2.2 3 35 43 19–30 1500 2300 4700 1000 700 400 8 11 150 55 900 2.3 4 35 45 31–50 1500 2300 4700 1000 700 420 8 11 150 55 900 2.3 4 35 45 51–70 1300 2000 4700 1200 700 420 8 11 150 55 900 2.3 4 30 45 (cid:2)70 1200 1800 4700 1200 700 420 8 11 150 55 900 2.3 4 30 45 Females 9–13 1500 2300 4500 1300 1250 240 8 8 120 40 700 1.6 2 21 34 14–18 1500 2300 4700 1300 1250 360 15 9 150 55 890 1.6 3 24 43 19–30 1500 2300 4700 1000 700 310 18 8 150 55 900 1.8 3 25 45 31–50 1500 2300 4700 1000 700 320 18 8 150 55 900 1.8 3 25 45 51–70 1300 2000 4700 1200 700 320 8 8 150 55 900 1.8 3 20 45 (cid:2)70 1200 1800 4700 1200 700 320 8 8 150 55 900 1.8 3 20 45 Pregnancy ≤18 1500 2300 4700 1300 1250 400 27 12 220 60 1000 2.0 3 29 50 19–30 1500 2300 4700 1000 700 350 27 11 220 60 1000 2.0 3 30 50 31–50 1500 2300 4700 1000 700 360 27 11 220 60 1000 2.0 3 30 50 Lactation ≤18 1500 2300 5100 1300 1250 360 10 13 290 70 1300 2.6 3 44 50 ES3 19–30 1500 2300 5100 1000 700 310 9 12 290 70 1300 2.6 3 45 50 31–50 1500 2300 5100 1000 700 320 9 12 290 70 1300 2.6 3 45 50 Tolerable Upper Intake Levels (UL) for Vitamins Age (yr) Niacin(mg/day)aVitami(n mBg/6day)Folate(µg/day)aCholin(emg/day)Vitami(n mCg/day)Vitami(µn gA/day)bVitami(µn gD/day)Vitami(n mEg/day)c Infants 0–0.5 — — — — — 600 25 — 0.5–1 — — — — — 600 25 — Children 1–3 10 30 300 1000 400 600 50 200 4–8 15 40 400 1000 650 900 50 300 Adolescents 9–13 20 60 600 2000 1200 1700 50 600 14–18 30 80 800 3000 1800 2800 50 800 Adults 19–70 35 100 1000 3500 2000 3000 50 1000 (cid:2)70 35 100 1000 3500 2000 3000 50 1000 Pregnancy ≤18 30 80 800 3000 1800 2800 50 800 19–50 35 100 1000 3500 2000 3000 50 1000 Lactation ≤18 30 80 800 3000 1800 2800 50 800 19–50 35 100 1000 3500 2000 3000 50 1000 aThe UL for niacin and folate apply to synthetic forms obtained bThe UL for vitamin A applies to the preformed vitamin only. from supplements, fortifi ed foods, or a combination of the cThe UL for vitamin E applies to any form of supplemental two. (cid:4)-tocopherol, fortifi ed foods, or a combination of the two. Tolerable Upper Intake Levels (UL) for Minerals m Age (yr) Sodiu(mmg/day)Chlori(demg/day)Calciu(mmg/day)Phosp(homrgu/sday)Magn(esimug/mday)dIron(mg/day)bZinc(mg/day)Iodine(µg/day)Seleni(uµmg/day)Coppe(µrg/day)Manga(nmegs/eday)Fluorid(emg/day)Molyb(µdegn/uday)Boron(mg/day)Nickel(mg/day) Infants 0–0.5 —e —e — — — 40 4 — 45 — — 0.7 — — — 0.5–1 —e —e — — — 40 5 — 60 — — 0.9 — — — Children 1–3 1500 2300 2500 3000 65 40 7 200 90 1000 2 1.3 300 3 0.2 4–8 1900 2900 2500 3000 110 40 12 300 150 3000 3 2.2 600 6 0.3 Adolescents 9–13 2200 3400 2500 4000 350 40 23 600 280 5000 6 10 1100 11 0.6 14–18 2300 3600 2500 4000 350 45 34 900 400 8000 9 10 1700 17 1.0 Adults 19–70 2300 3600 2500 4000 350 45 40 1100 400 10,000 11 10 2000 20 1.0 (cid:2)70 2300 3600 2500 3000 350 45 40 1100 400 10,000 11 10 2000 20 1.0 Pregnancy ≤18 2300 3600 2500 3500 350 45 34 900 400 8000 9 10 1700 17 1.0 19–50 2300 3600 2500 3500 350 45 40 1100 400 10,000 11 10 2000 20 1.0 Lactation ≤18 2300 3600 2500 4000 350 45 34 900 400 8000 9 10 1700 17 1.0 19–50 2300 3600 2500 4000 350 45 40 1100 400 10,000 11 10 2000 20 1.0 dThe UL for magnesium applies to synthetic forms obtained from supplements or drugs only. SOURCE: Adapted with permission from the Dietary Reference Intakes series, National Academies eSource of intake should be from human milk (or formula) and food only. Press. Copyright 1997, 1998, 2000, 2001, by the National Academy of Sciences. Courtesy of the NOTE: An Upper Limit was not established for vitamins and minerals not listed and for those age National Academies Press, Washington, D.C. groups listed with a dash (—) because of a lack of data, not because these nutrients are safe to consume at any level of intake. All nutrients can have adverse effects when intakes are excessive. Acceptable Macronutrient Distribution Ranges (AMDR) Range (percent of energy) Children, Children, Adults Macronutrient 1–3 years 4–18 years 19(cid:3) years Fat 30–40 25–35 20–35 (cid:6)-6 polyunsaturated acidsa 5–10 5–105 –10 (linoleic acid) (cid:6)-3 polyunsaturated fatty acidsa 0.6–1.2 0.6–1.2 0.6–1.2 (linolenic acid) Carbohydrate 45–65 45–65 45–65 Protein 5–20 10–30 10–35 aApproximately 10% of the total can come from longer-chain (cid:6)-3 or (cid:6)-6 fatty acids. SOURCE: Adapted from Institute of Medicine, Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Choles- terol, Protein, and Amino Acids, National Academies Press; Washington, D.C., 2005. This page intentionally left blank Second Edition Nutritional Sciences From Fundamentals to Food Michelle McGuire, PhD Washington State University Kathy A. Beerman, PhD Washington State University Australia • Brazil • Japan • Korea • Mexico • Singapore • Spain • United Kingdom • United States i Nutritional Sciences: From Fundamentals © 2011 Wadsworth Cengage Learning to Food, Second Edition ALL RIGHTS RESERVED. No part of this work covered by the copyright herein Michelle McGuire and Kathy A. Beerman may be reproduced, transmitted, stored or used in any form or by any means Nutrition Editor: Peggy Williams graphic, electronic, or mechanical, including but not limited to photocopying, recording, scanning, digitizing, taping, Web distribution, information networks, Developmental Editors: Nedah Rose, or information storage and retrieval systems, except as permitted under Shelley Parlante Section 107 or 108 of the 1976 United States Copyright Act, without the prior Assistant Editor: Elesha Feldman written permission of the publisher. 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To learn more about Wadsworth, visit www.cengage.com/wadsworth Purchase any of our products at your local college store or at our preferred online store www.ichapters.com Printed in the United States of America 1 2 3 4 5 6 7 13 12 11 10 09 Contents in Brief 1 Chapter The Science of Nutrition 3 2 Chapter Nutritional Assessment and Dietary Planning 33 3 Chapter Chemical, Biological, and Physiological Aspects of Nutrition 73 4 Chapter Carbohydrates 123 Nutrition Matters Nutrition, Diabetes, and Metabolic Syndrome 159 5 Chapter Protein 175 Nutrition Matters Food Safety 214 6 Chapter Lipids 233 Nutrition Matters Nutrition and Cardiovascular Health 273 7 Chapter Energy Metabolism 287 Nutrition Matters Alcohol, Health, and Disease 322 8 Chapter Energy Balance and Body Weight Regulation 341 Nutrition Matters Disordered Eating 386 9 Chapter Physical Activity, Health, and Sports Nutrition 405 10 Chapter Water-Soluble Vitamins 439 11 Chapter Fat-Soluble Vitamins 483 Nutrition Matters Nutrition and Cancer 515 12 Chapter The Major Minerals 531 Nutrition Matters Nutrition and Bone Health 567 13 Chapter The Trace Minerals 579 14 Chapter Life Cycle Nutrition 611 Nutrition Matters Food Insecurity, Hunger, and Malnutrition 662 Appendixes A Aids to Calculation A-2 B Estimated Energy Requirement (EER) Calculations and Physical Activity (PA) Values A-4 C Summary of the USDA Dietary Guidelines for Americans (2005) A-6 D The Exchange System A-9 E Answers to Review Questions and Practice Calculations A-15 Glossary G-1 Index I-1 iii Contents Chapter 1 The Science of Nutrition 3 Everybody Has a Story Choosing Nutrition Step 3: Data Are Collected to Test the Hypothesis 15 • as a Career Path 4 Intervention Studies Should Be Used to Test for Causality 16 What Do We Mean by “Nutrition”? 5 Are All Nutrition Claims Believable? 19 Nutrients Support and Fuel All We Do 5 • Foods Contain Determine the Source of the Information 20 • Credibility Nutrients and Nonnutrients 5 • Organic Nutrients Are of the Researchers Is Important 21 • Who Paid for the Different from Organic Foods 6 Research? 21 • Evaluate the Appropriateness of the Focus on Foods Understanding What Is Meant by “Organic Experimental Design 21 • Do Public Health Organizations Concur? 21 Foods” 7 Nutrition and Health: What Is the Connection? 22 Functional Foods Have Extra Nutrients, Phytochemicals, and/or Zoonutrients 7 Public Health Agencies Assess the Health of the Nation 22 • Mortality and Morbidity Rates Measure Death and Illness What Are the Major Nutrient Classes? 8 Over Time 22 • Life Expectancy Has Increased Carbohydrates Are Vital for Energy and Regulatory Dramatically 23 • Diseases Are Either Infectious or Roles 8 • Proteins Make Up Muscles and Are Important for Noninfectious 23 • Chronic Diseases Have Replaced Energy and Regulation 9 • Lipids Are More Than Abundant Infectious Diseases 25 • Risk Factors Do Not Necessarily Energy Sources 9 • Water Is the Essence of Life Itself 9 • Cause Chronic Diseases 26 • Understanding Nutrition Is Vitamins Regulate Reactions and Promote Growth and More Important Than Ever 26 Development 9 • Minerals Provide Structure and Assist with Focus on Diet and Health Industrialization, Population Regulation 10 Growth, and the Nutrition Transition 27 How Do Foods Provide Energy? 10 Calories Represent the Amount of Energy in a Food 11 How Do Nutritional Scientists Conduct Their Research? 13 Step 1: The Observation Must Be Accurate 13 • Step 2: A Hypothesis Makes Sense of an Observation 13 • Chapter 2 Nutritional Assessment and Dietary Planning 33 Everybody Has a Story Coping with College Food Can be Estimated Average Requirements (EARs) Refl ect a Population’s Diffi cult for Foreign Students 34 Average Need 43 • Recommended Dietary Allowances (RDAs) Are Recommended Intake Goals for Individuals 44 • What Do We Mean by “Nutritional Status”? 35 Adequate Intake (AI) Levels Were Set When Data Were Primary and Secondary Malnutrition Can Lead to Poor Lacking for EARs 45 • Tolerable Upper Intake Levels (UL) Nutritional Status 35 • Adequate Nutrient Intake Can Be Refl ect Safe Maximal Intakes 45 • Energy Intake Can Also Be Different Among Individuals 36 Assessed 46 How Is Nutritional Status Assessed? 36 How Can You Easily Assess and Plan Your Diet? 48 Anthropometry: Body Measurements Provide Information Food Guidance Systems Have Been Part of Dietary Planning Concerning Nutritional Status 36 • Laboratory Tests Are for Decades 49 • 2005 Dietary Guidelines for Americans: Our Important Biochemical Indicators of Nutritional Status 37 • Current Recommendations 50 Clinical Evaluations Assess Signs and Symptoms of Food Matters Working Toward the Goal: Increasing Fruit Disease 38 • Analysis of Your Diet Can Also Be Helpful 38 • and Vegetable Intake 51 Food Composition Tables and Dietary Analysis Software Are Important Tools 39 MyPyramid Illustrates How to Put Recommendations into How Much of a Nutrient Is Adequate? 40 Practice 54 • Healthy People 2010 Outlines Our Nation’s Goals for Healthy Living 57 Dietary Reference Intakes (DRIs) Provide Reference Standards 40 • DRI Values Depend on Many Factors 41 • iv How Can You Use Food Labels to Plan a Healthy Can You Put These Concepts into Action? 64 Diet? 58 Step 1: Set the Stage and Set Your Goals 64 • Step 2: Assess Understand What Is Included on Nutrition Facts Panels 58 Your Nutritional Status 64 • Step 3: Set the Table to Meet Your Goals 65 • Step 4: Compare Your Plan with Your Focus on Food What Makes a Food Kosher? 60 Assessment: Did You Succeed? 65 • There Is No Time Like Focus on Food The Buy Fresh Buy Local Campaign 62 the Present 66 Look for Nutrient Content Claims and Health Claims 63 Chapter 3 Chemical, Biological, and Physiological Aspects of Nutrition 73 Everybody Has a Story Living with Kidney Disease 74 Focus on Clinical Applications Peptic Ulcers and Gastroesophageal Refl ux Disease 99 How Does Chemistry Apply to the Study of Nutrition? 75 The Small Intestine Is the Primary Site of Chemical Digestion and Nutrition Absorption 100 Atoms Are Fundamental Units of Matter That Make Up the World Around Us 76 • Chemical Bonds Enable Atoms to How Does the Body Circulate Nutrients and Eliminate Form Millions of Different Molecules 77 • Macromolecules Cellular Waste Products? 105 Are the Molecules of Life and Are Vital to Cell Function 78 • Nutrients Absorbed from the Small Intestine are Circulated Acid-Base Chemistry Is Important to the Study of Nutrition 79 to the Liver 105 • The Cardiovascular System Circulates Nutrients, Oxygen, and Other Substances 105 How Do Biological Molecules Form Cells, Tissues, Organs, and Organ Systems? 80 Focus On Clinical Applications Celiac Disease 106 Substances Cross Cell Membranes by Passive and Active The Lymphatic System Transports Fat-Soluble Nutrients Away Transport 80 • Cell Organelles Carry Out Specialized from the GI Tract 108 • The Kidneys Play an Important Role in Functions Critical for Life 82 • Groups of Specialized Cells Eliminating Cellular Waste Products 109 Make Up Four Types of Tissues 83 What Is the Role of the Large Intestine? 110 How Does the Digestive System Break Down Food The Large Intestine Aids in the Elimination of Solid Waste to Its Nutrient Components? 85 Products 110 The GI Tract Has Four Tissues Layers That Contribute to Focus On Clinical Applications Cranberry Juice the Process of Digestion 85 and Urinary Tract Infections 111 How Do Gastrointestinal Motility and Secretion Fluids and Electrolytes Are Absorbed and Reabsorbed in the of Digestive Juices Facilitate Digestion? 88 Large Intestine 111 • Microbial Action in the Large Intestine Gastrointestinal (GI) Motility Mixes and Propels Food in Breaks Down Undigested Food Residue 112 the GI Tract 89 • Gastrointestinal (GI) Secretions Aid Digestion Focus On Clinical Applications Irritable Bowel Syndrome and Protect the GI Tract 90 • Neural and Hormonal Signals and Infl ammatory Bowel Disease 113 Regulate Gastrointestinal Motility and Secretions 90 Focus On Clinical Applications Probiotic and Prebiotic How Does the GI Tract Coordinate Functions to Foods 114 Optimize Digestion and Nutrient Absorption? 92 The Large Intestine Stores and Eliminates Solid Waste Digestion Begins in the Mouth with Chewing and Products from the Body 115 Mixing Food 92 • The Esophagus Delivers Food to the Stomach 94 • Digestive Functions of the Stomach Include Storage, Mixing, and the Formation of Chyme 94 Chapter 4 Carbohydrates 123 Everybody Has a Story Living with Diabetes 124 What Are Complex Carbohydrates? 131 What Are Simple Carbohydrates? 125 Oligosaccharides Are Components of Cell Membranes 131 • Polysaccharides Differ by the Types and Arrangements of Monosaccharides Are Single Sugar Molecules 125 Sugar Molecules 131 Focus on Diet and Health Is High-Fructose Corn Syrup Focus on Food Are Nonsugar Sweeteners Benefi cial Contributing to the Obesity Epidemic? 128 to Health? 132 Disaccharides Consist of Two Monosaccharides 128 Contents v

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