Drug Calculations for Nurses 9780230231610_01_prels.indd 1 02/03/2011 12:04 This page intentionally left blank Drug Calculations for Nurses Context for Practice Kerri Wright 9780230231610_01_prels.indd 3 02/03/2011 12:04 © Kerri Wright 2011 All rights reserved. No reproduction, copy or transmission of this publication may be made without written permission. No portion of this publication may be reproduced, copied or transmitted save with written permission or in accordance with the provisions of the Copyright, Designs and Patents Act 1988, or under the terms of any licence permitting limited copying issued by the Copyright Licensing Agency, Saffron House, 6–10 Kirby Street, London EC1N 8TS. Any person who does any unauthorized act in relation to this publication may be liable to criminal prosecution and civil claims for damages. The author has asserted her right to be identiied as the author of this work in accordance with the Copyright, Designs and Patents Act 1988. First published 2011 by PALGRAVE MACMILLAN Palgrave Macmillan in the UK is an imprint of Macmillan Publishers Limited, registered in England, company number 785998, of Houndmills, Basingstoke, Hampshire RG21 6XS. Palgrave Macmillan in the US is a division of St Martin’s Press LLC, 175 Fifth Avenue, New York, NY 10010. Palgrave Macmillan is the global academic imprint of the above companies and has companies and representatives throughout the world. Palgrave® and Macmillan® are registered trademarks in the United States, the United Kingdom, Europe and other countries. ISBN: 978–0–230–23161–0 This book is printed on paper suitable for recycling and made from fully managed and sustained forest sources. Logging, pulping and manufacturing processes are expected to conform to the environmental regulations of the country of origin. A catalogue record for this book is available from the British Library. 10 9 8 7 6 5 4 3 2 1 20 19 18 17 16 15 14 13 12 11 Printed in China 9780230231610_01_prels.indd 4 02/03/2011 12:04 Contents List of Figures and Boxes vii Acknowledgements viii Introduction x List of Abbreviations xviii PART I – DRUG CALCULATIONS IN CONTEXT 1 Back to Basics! Calculating and understanding simple medicine dosages 3 Units of Measurement 3 Formulations 6 Labelling of Medications 7 Checking 12 Converting 19 Units 28 Ratios 28 Dosage per Weight 30 Divided Doses 34 Chapter Summary 35 References 37 2 The Next Step! Medicines expressed as weight/volume strengths 39 Weight/Volume 39 Halving Method 45 Doubling 48 Reducing Down to a Single Unit 51 Relationships 54 Syringes 58 Preilled Syringes 61 The Nursing Formula 62 Complex Questions using Weight and Volume 73 v 9780230231610_01_prels.indd 5 02/03/2011 12:04 vi Contents Chapter Summary 80 References 83 3 The Final Step! Calculations involving continuous infusions 85 Infusions 85 Fluid Replacement Therapy 88 Volumetric Infusion Devices 90 Manual Infusions 92 Percentages 103 Syringe Pumps 108 Dosage per Hour 114 Sliding Scales 117 Infusion Dosages per Weight 118 Syringe Drivers 125 Chapter Summary 133 PART II – PRACTICE AND ASSESSMENT 4 Maths Fitness Programme! Practice, practice, practice 139 Introduction 139 Test Your Maths Skills 140 Session One – Maths Fitness 143 Session Two – Maths Stamina 151 Session Three – How Supple Are You? 166 Session Four – Through the Pain Barrier! 174 Session Five – Running the 5K Maths Challenge! 180 5 How much have I learnt? A chance to evaluate your learning 183 Answers 215 Index 247 9780230231610_01_prels.indd 6 02/03/2011 12:04 List of Figures and Boxes Figures 1 Medications and the dosages expressed as weight/volume or weight for elixir, ampoules and tablets 7 2 Illustration of a medicine packet and labelling 7 3 Medicine labelled for an individual person 8 4 A side view of a medicine box showing the expiry date and batch number 8 5 An example of a medicine administration chart 9 Diagram illustrating how to estimate the amount of solution to administer 14 6 Illustrating the relationship between grams and milligrams 21 7 A normal syringe end and a syringe with a leur lock 40 8 Demonstration of how a weight/volume dosage is ‘manufactured’ 41 9 Patient requires only 5mg from the 20mg/2ml ampoule 44 10 A solution containing 10g/100ml 45 11 A visual representation of 10mg/0.5ml 56 12 Visual representation of 50mg in 2ml 57 13 Common syringes used in healthcare 59 14 A 1ml syringe showing the measurements and dosage of a 10mg/ml strength solution and indicating the volume containing an 8mg dose 60 15 Illustration of the reconstitution of 600mg benzypenicillin with 10ml water for injection 77 16 Diagram showing difference in plasma concentration levels between bolus and continuously infused drugs 86 17 Illustration of a burette in practice 88 18 An illustration of rate per hour for a 1000ml infusion bag prescribed over 10 hours 89 19 A giving set packet showing the number of drops/ml 93 20 Intravenous medicine administration chart 99 vii 9780230231610_01_prels.indd 7 02/03/2011 12:04 viii List of Figures and Boxes 21 Illustration of how a 5% infusion is ‘made’ 104 22 A syringe showing rate of millilitres/hr 109 23 A syringe showing 20mls set at 4ml/hr 110 24 Illustration of how to set up the syringe for a syringe pump 112 25 Diagram showing a 10ml syringe with the volume measuring 48mm for a syringe driver 126 Boxes i Sample solution xiv 1 Common measurements used in drug dosages, with abbreviations 3 2 Measurement types and explanations 4 3 Common formulations for drugs 6 4 Summary of the common routes, abbreviations and usual dose for this route 11 5 Checking your solution to drug calculations 13 6 Conversion 20 7 Step by step guide – calculating number of tablets or ampoules to administer 26 8 Explanation of dosages used for adrenaline 29 9 Step by step guide – calculating number of tablets or ampoules to administer when prescribed as dose per weight 33 10 Syringes 40 11 Visual representation of relationship between prescribed dose and available dose 55 12 Long division procedure for the sum 31 divided by 10 66 13 Step by step guide to solving weight volume calculations 74 14 Different types of electronic devices for infusions 86 15 Illustration of the drip rate compared to seconds 102 16 Common rates for continuous intravenous infusions 102 17 An example of an insulin sliding scale 117 18 Similarities and differences between a syringe pump and a syringe driver 125 9780230231610_01_prels.indd 8 02/03/2011 12:04 Acknowledgements I would like to thank the following people for their help with reading and checking through early drafts of this book; Cathy Maylin, Anita Lutchman, Terry Ferns and Philip Marini. I would also like to thank all my colleagues at University of Greenwich who have readily given their time to help me in my research on this topic and the students who have been enthusiastic recipi- ents of my teaching and ideas and have continually inspired me to rethink and reine my thoughts. Finally, I’d like to thank Professor Liz Meerabeau who has been a constant encouragement and believer in my work on drug calculations, Pat Williams for her love and compassion and Kate Llewellyn, Project Editor, who has been a patient and thoughtful motivator throughout this project. However, my acknowledgements would not be complete without heartfelt thanks to my partner Joanna and our daughter Bethany; to them the thanks are for everything. ix 9780230231610_01_prels.indd 9 02/03/2011 12:04