Table Of Content

NMR for Physical and Biological Scientists NMR for Physical and Biological Scientists Thomas C. Pochapsky and Susan Sondej Pochapsky Brandeis University Waltham, Massachusetts Vice President Denise Schanck Senior Editor Robert L. Rogers Associate Editor Summers Scholl Senior Publisher Jackie Harbor Production Editor Karin Henderson Cover Designer Aktiv Typesetter Phoenix Photosetting Printer RR Donnelly © 2007 by Garland Science, a member of the Taylor & Francis Group, LLC This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. No part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. ®Mathematica is a registered trademark of Wolfram Research, Inc. ®Mathcad is a registered trademark of Mathsoft Engineering & Education, Inc. ®MATLAB is a registered trademark of The Mathworks, Inc. ISBN 0 8153 4103 2 Library of Congress Cataloging-in-Publication Data Pochapsky, Thomas C. NMR for physical and biological scientists/Thomas C. Pochapsky and Susan Sondej Pochapsky. p. ; cm. Includes bibliographical references and index. ISBN 0-8153-4103-2 (alk. paper) 1. Nuclear magnetic resonance spectroscopy. 2. Nuclear magnetic resonance. I. Pochapsky, Susan Sondej. II. Title. [DNLM: 1. Magnetic Resonance Spectroscopy. QU 25 P739n 2006] QP 519.9.N83P63 2006 543’.66–dc22 2006019638 Published in 2007 by Garland Science, member of the Taylor & Francis Group, LLC, 270 Madison Avenue, New York, NY 10016, USA and 2 Park Square, Milton Park, Abingdon, Oxon, OX14 4RN, UK. Printed in the United States of America on acid-free paper. 10 9 8 7 6 5 4 3 2 1 Visit our web site at http//www.garlandscience.com To our children, Elizabeth and Theodore and our parents, Eugene and Mary Pochapsky and Bob and Mary Ann Sondej CONTENTS Preface Symbols and fundamental constants 1. What is spectroscopy? A semiclassical description of spectroscopy Damped harmonics Quantum oscillators The spectroscopic experiment Ensembles and coherence Types of spectroscopy Practical considerations in spectroscopy Acquiring a spectrum Resolution: the problem of line width Line shape Problems 2. Elementary aspects of NMR: I. Introduction to spins, ensemble behavior and coupling Nuclear and electronic spin The quantum picture of nuclear spin The “spinning top” model of nuclear spin