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Neurologic Clinics 1993: Vol 11 Index PDF

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CUMULATIVE INDEX 1993 Volume 11 February BEHAVIORAL NEUROLOGY, pages 1-237 NEUROCARDIOLOGY, pages 239-501 NEUROLOGIC COMPLICATIONS OF DRUG AND ALCOHOL ABUSE, pages 503-735 November EPILEPSY I: DIAGNOSIS AND TREATMENT, pages 737-990 Note: Page numbers of issue and article titles are in boldface type. Abdominal pain, recurrent, seizures and, abuse of, cerebellar degeneration due to, 743 628 Abscess, brain, drug-related, 596 dementia due to, 646-655. See also De- infective endocarditis and, 425-426 me;:tia, alcoholic, primary. neurologic complications, 447-448 dyskinesias due to, 627-628 Absence seizure(s), 761-763 essential myoclonus due to, 626 Abstinence, precipitated, described, 508 essential tremor due to, 625-626 protracted, described, 508 fetal effects, 711-715. See also Fetal al- Abulia, cognitive rehabilitation in, 47 cohol syndrome. Acquired epileptic aphasia, 764 CNS involvement, 713-714 Acquired hepatocerebral degeneration, growth-related, 713 645-646 malformations, 712-713 Acquired immunodeficiency syndrome neurobehavioral, 714-715 (AIDS), clinical syndromes of, 609 movement disorders due to, 625-629 defined, 605 muscular effects, 700-701 epidemiology, 606 nerve root effects, 697-698 stroke in, 578-579 neurologic complications, issue on, Acute brain syndrome, infective 503-728 endocarditis and, 426 Parkinson’s disease due to, 626 Acute tolerance, described, 507 peripheral nerve effects, 697-698 Addiction, described, 509 plexus effects, 697-698 Adolescents, hashish use by, 665 postnatal, 714 marijuana effects on, 667-668 pregnancy effects, 713 marijuana use by, 665 seizures related to, 565-569. See also Affective disorders. See also Depression. Seizure(s), alcohol-related. bipolar, in multiple sclerosis, 199 stroke related to, 585-586 Afferent nerve fibers, cardiac, 240-241 withdrawal parkinsonism due to, 627- Afferent receptors, in neural cardiovascular 628 control, 258-259 Alcohol intoxication, seizures and, 746 Age, as factor with opioid use, 515-516 Alcohol liver disease, movement disorders Aggression, epilepsy and, 139-140 associated with, 628-629 Aging, premature, alcoholism and, 211 Alcohol tremor, 626-627 AIDS. See Acquired immunodeficiency Alcohol withdrawal, role of, 566-567 syndrome. Alcohol withdrawal seizure(s), clinical Alcohol. See also Ethanol. features, 567-568 974 CUMULATIVE INDEX 1993 Alcohol withdrawal seizure(s) (Continued) intracranial mycotic, infective endocardi- management, 569 tis and, 425 pathophysiology, 566 left ventricular, postinfarction, 405-406 Alcohol withdrawal syndrome, fetal effects, Anosognosia, cognitive rehabilitation in, 715 44-46 Alcoholic cerebellar degeneration, ethanol Antibiotics, in infective endocarditis, 431- and, 527 432 Alcoholism, cognitive impairment due to, Anticholinergic(s), abuse of, side effects, recoverability of, 212-213 559 epiiepsy due to, 568 described, 559 muscular effects, 700-701 Anticoagulants, in infective endocarditis, neuropsychologic changes due to, 205- 433-434 218 Antiepileptic drug(s) (AEDs), in the affect and cognitive factors, 210-211 elderly, 793-798 alcoholic history in, 211 interactions among, 905-922 childhood behavioral problems, 211- pharmacodynamic, 907-908 212 pharmacokinetic, 908-909 family history, 212 metabolism of, in pregnancy, 778 models, 207 new, 923-949 nature and severity of impairment, in pregnancy, 777-786 206-207 for seizures, 767-770 premature aging, 211 adverse effects, 770-771 prevalence, 205 Antioxidant(s), in epilepsy prevention, Algorithm, point D2, ventricular fibrillation 829-830 and, 340-345 Antiperoxidant(s), in epilepsy prevention, Alzheimer’s disease, depression in, 91 829 Amitryptiline, myasthenic effects Anxiety disorders, epilepsy and, 137-138 exacerbated by, 700 Aorta, coarctation of, neurologic Amnesia, transient global, seizures and, complications, 446 744-745 Aortic stenosis, balloon valvuloplasty for, 394-395 Amnestic syndrome, and alcoholic Aortic valve disease, stroke and, 392 dementia, 205-208 Aphasia Research Center at the Boston Amphetamine(s), 670-675 Veterans Administration Hospital, 5 abuse of, clinical effects, acute, 541-542 Aprosodias, 13-16 cognitive effects, 688 defined, 13 movement disorders due to, 633 in tone languages, 16 muscular effects, 702 Aprosody, defined, 11 nerve root effects, 699 Arotic arch chemoreceptors, in neural perceptual and psychomotor effects, cardiovascular control, 258 672-675 Arrhythmia, 375-390. See also specific peripheral nerve effects, 699 types, e.g., Bradyarrhythmia. plexus effects, 699 brain regulation of, 329-330 seizures due to, 571-572 in CNS disease, 245-246, 248-250 stroke related to, 582-583 epilepsy and, 298-299 chemistry of, 671-672 fatal, brain mechanisms underlying, 325- compulsive use of, 542 351. See also Neurocardiology. dependence upon, 542 neural control of heart and, 248-250 described, 536-537 neurologic complications, 449-450 epidemiology, 670 stress-induced, 246, 302-304 hallucinogenic, 540-541 stroke and, 297-298, 387-388 history, 670-671 sudden death due to, 304, 326 pharmacology of, 539-540, 671-672 syncope and, 375-387 routes and patterns of administration, ventricular, pathogenesis, nervous sys- 537-538 tem in, experimental studies, 294— tolerance to, 542 299 Analgesia, opioids and, 510 human studies, 299-301 Aneurysm, atrial septic, echocardiography Arrhythmogenesis, cerebrovascular disease in, 359 and, 300-301 CUMULATIVE INDEX 1993 975 CNS in, 297-299, 300-301 history, 1-8 in normal hearts, brain regulation of, issue on, 1-231 330-338 neuropsychologic testing in, 219-231. See parasympathetic nervous system in, 294— also Neuropsychologic testing, in be- 297, 299-300 havioral neurology. stress and, 302-304 Benign paroxysmal vertigo of childhood, Artificial heart, total, cerebrovascular seizures and, 743 complications, 465-466 Benzodiazepine(s), abuse of, 529-530 Asymmetry, brain, in developmental acute effects, 529-530 dyslexia, 162-165 overdose of, 529-530 Atherosclerosis, aortic, echocardiography withdrawal from, 530 in, 360-361 for status epilepticus, 845-851 Atrial fibrillation, echocardiography in, 358 Bilateral synchrony, secondary, 874 Atrial pressure/ volume receptors, in Bipolar affective disorder, in multiple neural cardiovascular control, 258 sclerosis, 199 Atrial septal defect, silent, neurologic Blood viscosity, abnormalities in, total complications, 444-446 artificial hearts and, 470-471 Atrioventricular conduction disturbances, Botulism, drug-related, 596 377-379 Bradyarrhythmia, syncope due to, 375-379 Attention, multiple sclerosis effects on, Brain, abscess of, drug-related, 596 192-193 asymmetry of, in developmental dys- Attention deficit hyperactivity disorder, in lexia, 162-165 adults, 113-117 biopsy of, in HIV infection, 617-618 causes, 69 dysfunction of, in depression, 85-87 diagnostic criteria for, 61 imaging techniques of, 5 vigilance and, relationship between, 69 pathways to heart, 294 Attention deficit hyperactivity disorder in regulation of arrhythmias, 329-330 symptom complex, 69-71 in regulation of arrhythmogenesis in nor- Auditory system, cocaine effects on, 718 mal hearts, 330-338 Aura(s), frontal lobe seizures and, 813 regulation of heart by, rationale, 327-329 temporal lobe seizures and, 806 regulation of heartbeat by, 329-330 Autism, clinical features, 176 tumors of, MRI detection of, 884-885 hypothesized abnormal circuit in, 183 Brain abscess, drug-related, 596 inferior olive and cerebellar nuclei in, infective endocarditis and, 425-426 180 neurologic complications, 447-448 limbic system involvement in, 176-177 Brain injury, seizures and, biochemical neuropathologic studies of, 175-187 effects, 825 methods and materials, 175-181 mechanisms of, 824-825 responses to, alteration of, 829-830 Breath holding, 741-743 incidence, 741 Balloon valvuloplasty, for mitral stensosis pathophysiologic basis for, 742 and aortic stenosis, 394-395 reflex anoxic seizures and, 742-743 Barbiturate(s), absorption of, 914 types, 742 abuse of, 529-530 Broca, Paul, 3-4 acute effects, 529-530 Bromide, abuse of, 530-531 overdose of, 529-530 Buprenorphine, 507 withdrawal from, 530 for opioid addiction, 519 elimination of, 915 Buspirone, abuse of, 531 protein binding of, 915 Baroreceptors, in neural cardiovascular control, 258 Behavior, changes in, epilepsy and, 127- Calciferol, in neurogenic heart disease, 149. See also Epilepsy, behavioral changes 285-286 associated with. Capillary permeability, altered, neurogenic in childhood, and adult alcoholism, 211- pulmonary edema and, 313-314 212 Carbamazepine, absorption of, 911 neurology of, 1 drug interactions with, 912 Behavioral neurology, defined, 1 elimination of, 911-913 976 CUMULATIVE INDEX 1993 Carbamazepine (Continued) Cerebrocortical anomalies, in for epilepsy in the elderly, 795-796 developmental dyslexia, 165-169 metabolism of, 911-913 Cerebrospinal fluid examination, in protein binding of, 911 infective endocarditis, 429-430 Carbamazepine syndrome, 782 Cerebrovascular accidents, cocaine and, Cardiac. See Heart. 546-547 Cardiac afferents, neuroanatomy, 240-241 Cerebrovascular disease, arrhythmogenesis Cardiac catheterization, neurologic and, 300-301 complications, 450-451 drug-related, 578 Cardiac efferents, neuroanatomy, 241-242 seizures and, 745-746 Cardiac lesions, right-to-left shunt, in the elderly, 790-791 neurologic complications, 441-444 Children, seizures and epilepsy in, 755-775 Cardiac surgery, neurologic complications, Chorioretinitis, drug-related, 595 452-454 Cingulate gyrus, seizures in, 816 Cardiac valvular disease, echocardiography Circulatory support devices, artificial, in, 361-362 blood-artificial surface interactions in, Cardiovascular regulation, neuroanatomy, 471-472 240-242 centrifugal pumps, 464-465 Cardiovascular status, neural control of, cerebrovascular complications, 463-474 afferent limb, 258-259 disturbed blood flow patterns in, 470 efferent limb, 259-262 infection in, 471 Carotid sinus chemoreceptors, in neural rheologic factors in, 470-471 cardiovascular control, 258 total artificial heart, 465-466 Carotid sinus sensitivity, 739-740 types, 464-470 Cataplexy, 747-748 ventricular assist devices, 466-470 Catecholamines, in neurogenic heart Clobazam, described, 925 disease, 246-247, 284-285 Clonidine, for opioid addiction, 519 Catheterization, cardiac, neurologic CNS. See Central nervous system. complications, 450-451 Cocaine, abuse of, cerebral vasculitis due CBAG surgery. See Coronary artery bypass to, 547 graft (CABG) surgery. cerebrovascular accidents due to, 546- Central nervous system (CNS), in 547 arrhythmogenesis, 297-299, 300-301 clinical effects, acute, 541-542 cardiac damage by, 273-292 CNS infection due to, 547-548 in CBAG surgery, 475-495. See also Coro- cognitive effects, 688 nary artery bypass graft (CABG) sur- fetal effects, 715-719 gery. auditory, 718 in fetal alcohol syndrome, 713-714 intrauterine growth, 716 neuroanatomy, 275-276 neurobehavioral, 717 Central nervous system (CNS) disease, neurodevelopmental, 718-719 arrhythmias in, 245-246, 248-250 seizures, 717-718 ECG changes in, 257-272 SIDS, 718 morphology, 262-266 stroke, 717 rhythm disturbances and, 267 movement disorders due to, 545, 631- Central nervous system (CNS) infection, 633 cocaine and, 547-548 muscular effects, 701 Central pontine myelinolysis, ethanol and, myasthenic effects exacerbated by, 528 699-700 Centrifugal pumps, cerebrovascular neurologic complications, 543-549 complications, 464-465 long-term, 548-549 Cerebellar degeneration, alcoholic, 628 pregnancy effects, 545-546, 716 Cerebral dysfunction, in depression, 85-87 rhabdomyolysis due to, 548 Cerebral embolism, infective endocarditis seizures due to, 543-544, 569-571 and, 424-425 spinal cord diseases associated with, Cerebral ischemia, echocardiography in, 694-695 357-363 stroke related to, 581-582 Cerebral microemboli, following CBAG sudden death syndrome due to, 544 surgery, 481-493 tic disorders due to, 545 Cerebral vasculitis, cocaine-associated, 547 withdrawal symptoms, 719 CUMULATIVE INDEX 1993 977 childhood exposure to, 719 primary, 646-655 compulsive use of, 542 clinical evidence of, 647-650 dependence upon, 542 CT in, 651-653 described, 536 MRI in, 651-652 dystonic reactions to, 545 neuropathologic evidence, 653-655 pharmacology of, 538-539 pneumoencephalography in, 651- routes and patterns of administration, 653 537-538 psychologic evidence of, 650-651 tolerance to, 542 radiologic evidence of, 651-653 uses, 536 subcortical, multiple sclerosis as, 200-201 Cognitive impairment, in alcoholism, 212- Dependence, psychological, described, 509 213 Depression, 79-104 in multiple sclerosis, 189-197. See also Alzheimer’s disease and, 91 Multiple sclerosis, cognitive impairment cerebral dysfunction in, 85-87 in. conditions complicated by, 82 Cognitive/motor complex, HIV-1-- dementia and, 90-91 associated, 612 epilepsy and, 90, 135 Computed tomography (CT), in alcohol- multiple sclerosis and, 90, 198-199 related seizures, 568-569 myotonic dystrophy and, 90 in alcoholic dementia, 651-653 neurobiologic correlates of, 80-92 in cardiac lesions, 442-444 neurochemical basis of, 91-92 in infective endocarditis, 427-429 neuroendocrine dysfunction in, 83-84 in multiple sclerosis, 196-197 neurologic diseases associated with, 87- single-photon emission, in epilepsy, 894- 91 897 neurology of, implications for, 92-93 Confusion, cognitive rehabilitation in, 46- neurophysiologic changes in, 80-83 47 Parkinson’s disease and, 89-90 Congenital heart disease. See Heart disease, poststroke, 19 congenital. stroke and, 87-89 Constipation, opioids and, 510-511 symptoms, 81 Coronary artery bypass graft (CABG) symptoms complex of, 80 surgery, cerebral microemboli “Designer drugs,” 507-509, 683-684 following, 481-493 abuse of, cognitive effects, 688 CNS complications, 475-495 opioid, 507-509 prevalence, 475-477 Development, epilepsy during pregnancy hypotension following, 479-481 effects on, 779-782 nonpulsatile cerebral perfusion in, 490 Diazepam, for status epilepticus, 845-851 stroke following, 478-479 Dissociative disorders, psychiatric, epilepsy transcranial Doppler analysis during, and, 138-139 487-488 Drug(s). See also specific types and drug Coronary artery disease, 399-417 ames. echocardiography in, 3 abuse of. See Drug abuse. in neurovascular disease, 363 antiepileptic. See Antiepileptic drug(s). prevalence, 363 “designer,” 683-684 screening for, 363-366 abuse of, cognitive effects, 688 testing for, 366-367 overdose of, seizures and, 746-747 Corpus callosotomy, in epilepsy, 966 Drug abuse. See also Substance abuse. Cough suppression, opioids and, 511 amphetamines, 670-675 “Crack”, described, 536 anticholinergics, 559 muscular effects, 701 barbiturates, 529-530 CT. See Computed tomography. benzodiazepines, 529-530 cerebrovascular disease due to, 578 “designer drugs,” 683-684 ethanol, 523-529 Death, sudden. See Sudden death. fetal effects, 707-728 Deja vu, temporal lobe seizures and, 807- hallucinogens, 557-558, 681-683 hypnotics, 675-677 Delirium tremens, ethanol and, 526 infections due to, 591-603 Dementia, alcoholic, 205-208 botulism, 596 978 CUMULATIVE INDEX 1993 Drug abuse (Continued) Echocardiography, in cardiac surgery, 368- brain abscess, 596 369 chorioretinitis, 595 in cerebral ischemia, 357-363 endophthalmitis, 595 in coronary artery disease, 363-367 fasciitis, 593-594 in infective endocarditis, 430-431 frontal osteomyelitis, 596 intraoperative, 367-369 hepatitis, 598-599 in neurologic disorders, 353-374 infective endocarditis, 591-592 in noncardiac surgery, 367-368 malaria, 598 in syncope, 369 meningitis, 596 techniques, 354-357 optic neuropathy, 596 “Ecstasy,” 540-541, 683-684 pyomyositis, 593-594 ECT. See Electroconvulsive therapy. sinusitis, 596 Edema, pulmonary. See Pulmonary edema. social implications, 600 opioids and, 513 syphilis, 598 EEG. See Electroencephalography. tetanus, 594-595 Efferent nerve fibers, cardiac, 241-242 tuberculosis, 599-600 Efferent receptors, in neural cardiovascular vertebral and epidural spinal, 596-598 control, 259-262 inhalants, 558-559, 677-681 Elderly, seizures and epilepsy in, 787-804. intravenous, infective endocarditis and, See also Seizure(s), in the elderly. 422 Electrocardiography (ECG), in CNS disease, 257-272 long-term, cognitive effects, 688 morphology, 262-266 marijuana, 556-557, 664-670 in heart function, 244-245, 246-248 MDMA, 683-684 neurogenic changes in, 262-268 muscle disorders due to, 700-702 defined, 281 neurologic complications, issue on, 503- Electroconvulsive therapy (ECT), in grand mal seizures, 152-153 neuromuscular junction effects, 700 Electroencephalography (EEG), in alcohol- opiates, 685-687 related seizures, 568 opioids, 503-521 in epilepsy, 857-881. See also Epilepsy, phencyclidine, 555-556 EEG interpretation in. psychostimulants, 535-553 intracranial, in epilepsy, 960-964 sedatives, 675-677 in Parkinson’s disease, 862 seizures related to, 563-575. See also Sei- for seizures in the elderly, 791-792 zure(s), drug-related. in temporal and frontal lobe epilepsies, stroke related to, 577-590. See also 817 Stroke, drug-related. Embolism, cerebral, infective endocarditis Dyskinesia(s), alcohol-related, 627-628 and, 424—426 Dyslexia, in adults, 107-112 paradoxic, echocardiography in, 359 imaging techniques in, 108-110 Embolus(i), foreign body, stroke and, 579 developmental, anatomic and pathologic Emotion(s), ictal, temporal lobe seizures changes in, causes, 169-170 and, 808 brain asymmetry in, 162-165 lateralization of, 19-20 cerebrocortical anomalies in, 165-169 neurology of, 17-20 hallmark of, 161 Emotional disturbances, in multiple microdysgenesis in, 166-168 sclerosis, 197-201 microgyria in, 166-168 Encephalopathy, hepatic, ethanol and, 528 neuroanatomic basis of, 161-173 HIV infection and, 614-616 visual pathway changes in, 169 Wernicke, defined, 639 genetics of, 110-112 ethanol and, 526 Dysmorphism, facial, 782 Endocarditis, infective, antibiotics in, 431- Dysplasia, MRI detection of, 885-886 432 Dysprosody, defined, 11 anticoagulants in, 433-434 Dystonia, cocaine and, 545 brain abscess in, 425-426 cardiac surgery in, 434-435 cerebral embolism in, 424-425 clinical presentation, 424-427 EGG. See Electrocardiography. diagnosis, 427-431 CUMULATIVE INDEX 1993 979 drug-related, 591-592 identification of normal transients, encephalopathy in, 426 864-867 epidemiology, 419-422 pitfalls of, 877-879 headache in, 426 quantitative recordings, pitfalls of, incidence, 419-420 878-879 intracranial mycotic aneurysm in, 425 significant epileptiform activity, analy- in intravenous drug users, 422 sis of, 873-877 location in, 420-421 EEG monitoring in, intracranial, 960-964 management, 431-435 in the elderly, 787-804. See also Sei- meningitis in, 425-426 zure(s), in the elderly. microbiology of, 422-423 causes, 788, 789 neurologic complications, 419-440, 447 incidence, 787-788 neurosurgery in, 432 prevalence, 787-788 pathogenesis, 423-424 genius and, 133 prognosis, 435 incidence, 777, 787-788 prosthetic valve, 421-422 in infants and children, 755-775 seizures in, 426 MRI in, 884-889 stroke and, 577-578 neurogenic pulmonary edema and, 312- visual disturbances in, 427 313 Endophthalmitis, drug-related, 595 neuroimaging in, 883-903 personality changes due to, 127 Ephedrine, abuse of, stroke related to, 583 PET in, 889-893 pharmacology of, 540 positive traits in, 133 Epilepsia partialis continua, 838 pregnancy and, 777-786. See also Preg- Epilepsy. See also Seizure(s). nancy, epilepsy in. alcoholism and, 568 prevalence, 737 arrhythmias and, 298-299 psychopathology in, 133-135 behavioral changes associated with, 127- factors contributing to, 134 149 psychosocial stigma associated with, 738 aggression, 139-140 SPECT in, 894-897 altered sexuality, 131 sudden death and, 301 anxiety disorders, 137-138 surgery for, 951-971 depression, 135 contraindications, 954-955 dissociative disorders, 138-139 corpus callosotomy, 966 fear, 138 focal resective, 964-966 historical perspective, 128-129 for infantile spasms, 967 hypergraphia, 133 frontal lobectomy, 965-966 methodologic issues in, 129-130 frontiers of, 967 pathogenesis, 141-142 hemispherectomy, 967 personality changes due to, 130-133 invasive evaluation, 959-960 psychosis, 135-137 multiple subpial transections, 968 religiosity, 131-132 occipital lobectomy, 966 viscosity, 132-133 parietal lobectomy, 966 cocaine-related seizures and, 570-571 patient selection for, 952-955 cryptogenic, 756 presurgical evaluation, 955-959 depression in, 90 temporal lobectomy, 966-967 described, 737 temporal lobe, interictal hyposexuality diagnosis and treatment, issue on, 737— in, 131 971 types, 755-756 drugs for, interactions among, 905-922 Epilepsy syndrome, defined, 755 EEG interpretation in, 857-881 Epileptogenesis, cellular mechanisms of, assessment of transient or intermittent 826 activities, 859-860 Episodic dyscontrol, seizures and, 748-749 background activities, 857-859 Essential myoclonus, alcohol-related, 626 benign epileptiform variants, 868-873 Essential tremor (ET), alcohol-related, 625- identification of activity as cerebral in 626 origin, 860-864 Ethanol. See also Alcohol. identification of nonspecifically abnor- abuse of, acute effects, 524-526 mal activities, 867-868 altered mentation due to, 639-661 980 CUMULATIVE INDEX 1993 Ethanol (Continued) efficacy of, 942 central pontine myelinolysis due to, mechanisms of action of, 942 528 pharmacokinetics of, 942-943 cerebellar degeneration due to, 527 Fluorocortisol, in neurogenic heart disease, chronic effects, 526-529 285-286 hypoglycemia due to, 529 18-F-Fluorodeoxyglucose (FDG), in intoxication due to, 524 epilepsy, 889-892 Korsakoff amnestic syndrome due to, Foreign body emboli, stroke and, 579 527 Marchiafava-Bignami disease due to, 528 neurologic complications, 523-529 Gabapentin, absorption of, 917 overdose due to, 524 adverse effects, 931-932 pellagra due to, 527 chemical structure of, 906 Wernicke encephalopathy due to, 526 clinical use, 932 withdrawal from, delirium tremens described, 925 due to, 526 drug interactions with, 932 withdrawal from, 525-526 efficacy of, 930-931 seizures due to, 525-526 elimination of, 917-918 Ethchlorvynol, abuse of, 531 mechanisms of action of, 930 Euphoria, in multiple sclerosis, 198 metabolism of, 917-918 Executive dysfunction, 115-117 pharmacokinetics of, 931 protein binding of, 917 Gall, Franz Joseph, 2, 3 Gene(s), as factor in post-traumatic Facial dysmorphism, 782 seizures, 826-827 Fasciitis, drug-related, 593-594 Geschwind, Norman, 3, 4-5 Fear, ictal, epilepsy and, 138 Gestures, comprehension of, 15-16 Felbamate, absorption of, 916 defined, 11-12 adverse effects, 928 Gesturing, spontaneous affective prosody chemical structure of, 906 and, 13 clinical use, 929-930 Glutathione, in epilepsy prevention, 829 described, 925 Glutethimide, abuse of, 531 drug interactions with, 928-929 efficacy of, 927 elimination of, 916-917 mechanisms of action of, 926 Hallucination(s), temporal lobe seizures metabolism of, 916-917 and, 809-810 pharmacokinetics of, 927 Hallucinogen(s), 681-683 Fentanyl, 507 abuse of, cognitive effects, 688 Fetal alcohol syndrome (FAS), 712-715 perceptual and psychomotor effects, CNS involvement in, 713-714 682-683 growth-related effects, 713 side effects, 557-558 incidence, 712 chemistry of, 681-682 malformations due to, 712-713 described, 557 Fetal hydantoin syndrome (FHS), 781 epidemiology, 681 Fetal trimethadione syndrome, 781 history, 681 Fetus, alcohol abuse effects on, 711-715 pharmacology of, 681-682 cocaine effects on, 715-719 Hashish, high school students’ use of, 664 drug effects on, 707-728 Headache, infective endocarditis and, 426 marijuana, 710-711 Heart, artificial, cerebrovascular opiate effects on, 719-722 complications, 465-466 smoking effects on, 708-710 disturbed blood flow patterns in, 470 Flourens, 2 brain regulation of, rationale, 327-329 Flunarizine, adverse effects, 943 damage to, neurally induced, 273-292 chemical structure of, 906 function of, autonomic influences on, clinical use, 944 242-243 described, 925 catecholamines and, 246-247 drug interactions with, 943-944 clinical observations, 243-246 CUMULATIVE INDEX 1993 981 ECG changes in, 244-245, 246-248 Hexamethylpropyleneamineoxime experimental studies, 246-250 (HMPAO), in epilepsy, 894-896 parasympathetic control of, 261-262 Himmelsbach system for withdrawal pathophysiology, 246-250 behavior, 508 sympathetic control of, 259-261 HIV infection. See Human immunodeficiency neural control of, 239-256, 257 virus (HIV) infection. neuroanatomy, 274-278 Horner’s syndrome, surgery and, 454 pathways to brain, 294 Human immunodeficiency virus (HIV) surgery of, in infective endocarditis, 434— infection, 605-624 435 brain biopsy in, 617-618 Heart disease, congenital, neurologic classification, 607-609 complications, 441-462 clinical syndromes of, 609 arrhythmias, 449-450 cognitive /m otor complex related to, 612 brain abscess, 447-448 epidemiology, 605-607 coarctation of the aorta, 446 etiopathogenesis, 607-609 congenital, 448-449 neoplasms and, 613-617 infective endocarditis, 447 neurologic syndromes of, 610-613 postsurgical, 454 opportunistic infections and, 613-617 preexisting, 448-449 '3]-Hydroxyiodo-propyldianine (HIPDM), in epilepsy, 894-896 procedure-related, 450-458 right-to-left shunt lesions, 441-444 Hypergraphia, epilepsy and, 133 Hyperprosody, defined, 11 silent atrial septal defect, 444-446 Hypersynchrony, hypnogogic, 865 spontaneous, 441-450 Hypertension, acute, stroke and, 579 ventricular septal defect, 446 Hyperventilation, seizures and, 743 neurogenic, 281-290 Hypnotic(s), 675-677 catecholamine infusion in, 284-285 abuse of, cognitive effects, 688 history of, 281-284 perceptual and psychomotor effects, nervous system stimulation in, 286- 676-677 287 epidemiology, 675 pathogenesis, 289 history, 675-676 production of, 284-290 Hypoglycemia, ethanol and, 529 reperfusion in, 288-290 Hypotension, following CBAG surgery, steroids in, 285-286 479-481 stress in, 285-286 Hypothalamic lesions, pulmonary edema Heart transplantation, cerebrovascular in, 311-312 complications, 463-474 Hypovigilance, 69-71 Heartbeat, low-dimensional chaos in, and ventricular fibrillation, 340-345 patterns of, ventricular fibrillation due to, 345-348 Illusion(s), temporal lobe seizures and, prediction of, 338-339 809-810 variability of, brain regulation of, 329- Imaging techniques, for brain, 5 330 Infant(s), seizures and epilepsy in, 755-775 Hemispherectomy, in epilepsy, 967 Infantile spasm(s), 759-760 Hemorrhage, intracranial, risk of, in focal resective surgery for, 967 myocardial infarction, 412-413 Infection, artificial hearts and, 471 Hepatic encephalopathy, ethanol and, 528 drug-related, 591-603 Hepatitis, drug-related, 598-599 spinal, epidural, drug-related, 596-598 Hepatocerebral degeneration, acquired, vertebral, drug-related, 596-598 645-646 Infective endocarditis. See Endocarditis, Heroin, abuse of, fetal effects, 719-722 infective. seizures due to, 572 Information processing, multiple sclerosis spinal cord diseases associated with, effects on, 192-193 695-696 Inhalant(s), 677-681 stroke related to, 582 abuse of, cognitive effects, 688 cost of, 504 nerve root effects, 699 street use of, 503-504 peripheral nerve effects, 699 Heterotopia(s), MRI detection of, 885-886 plexus effects, 699 982 CUMULATIVE INDEX 1993 Inhalant(s) (Continued) Left ventricular aneurysm, posinfarction, side effects, 558-559 405-406 chemistry of, 678 Lennox-Gastaut syndrome, 760-761 described, 558 Limbic system, in autism, 176-177 epidemiology, 677 Liver disease, alcoholic, movement history, 678 disorders associated with, 628-629 perceptual and psychomotor effects, 678- Lobectomy, frontal, in epilepsy, 965-966 680 occipital, in epilepsy, 966 pharmacology of, 678 parietal, in epilepsy, 966 Intelligence, multiple sclerosis effects on, temporal, in epilepsy, 966-967 191-192 Lorazepam, for status epilepticus, 845-851 Intracranial pressure, neurogenic LSD (lysergic acid diethylamide), 681-683 pulmonary edema and, 312 abuse of, stroke related to, 584 Intrauterine growth, cocaine effects on, 716 Lung(s), neuroanatomy, 274-278 '3]-N-Isopropyl-iodoamphetamine (IMP), Lung disease, neurogenic, 278-281 in epilepsy, 894-896 Lung fluid flux, physiology of, 309-311 Lymphoma, HIV infection and, 616 Lysergic acid diethylamide (LSD), 681-683 abuse of, stroke related to, 584 Jactatio capitis, 747 Jamais vu, temporal lobe seizures and, 807-808 Magnetic resonance imaging (MRI), in alcoholic dementia, 651-652 in cardiac lesions, 442-444 in dyslexia, 108-109 Khat shrub, 540 in epilepsy, 884-889 Kinesics, 11-12 abnormalities found, 884-887 affective, in right hemisphere, organiza- in clinical management, 887-889 tion of, 12-17 future directions, 889 defined, 11 in infective endocarditis, 428-429 gestural, 11-12 in multiple sclerosis, 196-197 Korsakoff’s syndrome, 205-218, 640 Malaria, drug-related, 598 determinants of, 208 Mania, following stroke, 88-89 ethanol and, 527 Marchiafava-Bignami disease, 644-645 recovery from, 208 ethanol and, 528 Marijuana, 664-670 abuse of, cognitive effects, 688 fetal effects, 710-711 Lamotrigine, absorption of, 918 muscular effects, 702 adverse effects, 934 perceptual and psychomotor effects, chemical structure of, 906 665-667 clinical use, 935-936 prenatal effects, 667 described, 925 side effects, 556 drug interactions with, 935 stroke related to, 585 efficacy of, 933-934 studies of, 668-669 elimination of, 918 adolescent user effects, 667-668 mechanisms of action of, 932-933 chemistry of, 665 metabolism of, 918 described, 556 pharmacokinetics of, 934 epidemiology, 664 protein binding of, 918 high school students’ use of, 664 Language, multiple sclerosis effects on, 192 history, 664-665 nonverbal aspects of, 9-23 pharmacology of, 665 tone, aprosodias in, 16 Melancholia, 79-104. See also Depression. Laughing, pathologic, in multiple sclerosis, Memory, multiple sclerosis effects on, 193- 198 195 Learning disabilities, in adults, 105-125 Meningitis, drug-related, 596 nonverbal, in adults, 118-121 HIV infection and, 614 Learning disabled, defined, 105 infective endocarditis and, 425-426

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