Table Of Content

Mutation Research, 256 (1991) 331-332 © 1991 Elsevier Science Publishers B.V. All rights reserved 0921-/8917 /3$034.5 0 Contents Volume 256 (1991) Research Papers Basal DNA damage in individual human lymphocytes with age N.P. Singh, D.B. Danner, R.R. Tice, J.D. Pearson, L.J. Brant, C.H. Morrell and E.L. Schneider (U.S.A.) Aging alters hepatic expression of insulin receptor and c-jun mRNA in the mouse P.L. Mote, J.M. Grizzle, R.L. Walford and S.R. Spindler (U.S.A.) Micronucleated lymphocytes in people occupationally exposed to potential environmental contaminants: the age effect L. Migliore, M. Parrini, I. Sbrana, C. Biagini, A. Battaglia and N. Loprieno (Italy) Heterogeneity in Alzheimer’s disease: evidence from cellular radiosensitivity and complementation of this phenotype P. Chen, C. Kidson and M. Lavin (Australia) Biochemical mechanisms by which reutilization of DNA 5-methylcytosine is prevented in human cells J.A. Vilpo and L.M. Vilpo (Finland) The formation of heart DNA adducts in F344 rats following dietary administration of heterocyclic amines E. Overvik, M. Ochiai, M. Hirose, T. Sugimura and M. Nagao (Japan) In vivo loss of telomeric repeats with age in humans J. Lindsey, N.I. McGill, L.A. Lindsey, D.K. Green and H.J. Cooke (U.K.) The effects of spermatozoal irradiation with X-rays on chromosome abnormalities and on development of mouse zygotes after delayed fertilization M.L. Boerjan and L.A. Saris (The Netherlands) Reduced DNA repair in progeria cells and effects of y-ray irradiation on UV-induced unscheduled DNA synthesis in normal and progeria cells S. Wang, C. Nishigori, T. Yagi and H. Takebe (Japan) Special Issue Cellular Ageing edited by S.1.S. Rattan Research Papers Cellular ageing: reflections and projections S.LS. Rattan (Denmark) Aging under glass L. Hayflick (U.S.A.) Chromatin reorganization during senescence of proliferating cells A. Macieira-Coelho (France) Changes in gene expression and DNA methylation in adrenocortical cells senescing in culture P.J. Hornsby, L. Yang, $.G. Raju and C.Y. Cheng (U.S.A.) Protein synthesis and the components of protein synthetic machinery during cellular ageing S.LS. Rattan (Denmark) Cellular ageing related proteins secreted by human fibroblasts C.S. Eleftheriou, N.B. Trakas and S.J. Tzartos (Greece) Actin cytoskeletal network in aging and cancer K.M.K. Rao and H.J. Cohen (U.S.A.) Involvement of microtubules in modifications associated with cellular aging M. Raes (Belgium) Changes in the cell surface of human diploid fibroblasts during cellular aging K. Yamamoto and M. Yamamoto (Japan) Oxidants and antioxidants in proliferative senescence M. Poot (Germany) 332 Homoeostatic imbalance during cellular ageing: altered responsiveness A. Derventzi and S.1.S. Rattan (Denmark) Ageing in the chick lens: in vitro studies R.M. Clayton, C.E. Patek, M.W. Head and J. Cuthbert (U.K.) Cellular ageing of Alzheimer’s disease and Down syndrome cells in culture G. Carmeliet, G. David and J.-J. Cassiman (Belgium) Differentiation of primary and secondary fibroblasts in cell culture systems K. Bayreuther, P.I. Francz, J. Gogol, C. Hapke, M. Maier and H.-G. Meinrath (Germany) Protein markers for cellular mortality and immortality R. Wadhwa, S.C. Kaul, Y. Ikawa and Y. Sugimoto (Japan) Senescence and the accumulation of abnormal proteins R.F. Rosenberger (U.K.) Negative growth effectors and cellular senescence A.L. Spiering and J.R. Smith (U.S.A.) Telomere loss: mitotic clock or genetic time bomb? C.B. Harley (Canada) DNA methylation and cellular ageing J. Catania and D.S. Fairweather (U.K.) A re-examination of the effects of ionizing radiation on lifespan and transformation of human diploid fibroblasts R. Holliday (U.K., Australia) Molecular genetic approaches to the study of cellular senescence Y. Ning and O.M. Pereira-Smith (U.S.A.) Somatic mutations and cellular aging: two-dimensional DNA typing of rat fibroblast clones P.E. Slagboom, E. Mullaart, S. Droog and J. Vijg (Netherlands) Genetic basis of limited cell proliferation T.B.L. Kirkwood (U.K.) [end of special issue| Contents, Vol. 256