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a LANGE medical book Clinical Morgan & Mikhail’s Anesthesiology F I F T H E D I T I O N John F. Butterworth IV, MD Professor and Chairman Department of Anesthesiology Virginia Commonwealth University School of Medicine VCU Health System Richmond, Virginia David C. Mackey, MD Professor Department of Anesthesiology and Perioperative Medicine University of Texas M.D. Anderson Cancer Center Houston, Texas John D. Wasnick, MD, MPH Steven L. Berk Endowed Chair for Excellence in Medicine Professor and Chair Department of Anesthesia Texas Tech University Health Sciences Center School of Medicine Lubbock, Texas New York Chicago San Francisco Lisbon London Madrid Mexico City Milan New Delhi San Juan Seoul Singapore Sydney Toronto MMoorrgg__FFMM__ii--xxiivv..iinndddd ii 1122//0022//1133 99::4433 AAMM Morgan & Mikhail’s Clinical Anesthesiology, Fifth Edition Copyright © 2013, 2006, 2002 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in the United States. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher. Previous editions copyright © 1996, 1992 by Appleton & Lange. 1 2 3 4 5 6 7 8 9 0 WCT/WCT 18 17 16 15 14 13 ISBN 978-0-07-162703-0 MHID 0-07-162703-0 ISSN 1058-4277 Notice Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs. This book was set in Minion Pro by Thomson Digital. The editors were Brian Belval and Harriet Lebowitz. The production supervisor was Sherri Souffrance. Project management was provided by Charu Bansal, Thomson Digital. The illustration manager was Armen Ovsepyan; illustrations were provided by Electronic Publishing Services. The designer was Elise Lansdon; the cover designer was Anthony Landi; cover illustration by Elizabeth Perez. Quad Graphics was printer and binder. McGraw-Hill books are available at special quantity discounts to use as premiums and sales promotions, or for use in corporate training programs. To contact a representative please e-mail us at [email protected]. International Edition ISBN 978-0-07-181669-4 ; MHID 0-07-181669-0. Copyright © 2013. Exclusive rights by The McGraw-Hill Companies, Inc., for manufacture and export. This book cannot be re-exported from the country to which it is consigned by McGraw-Hill. The International Edition is not available in North America. MMoorrgg__FFMM__ii--xxiivv..iinndddd iiii 1122//0022//1133 99::4433 AAMM Contents Chapter Authors v | Contributors vii Research and Review ix | Foreword xi | Preface xiii 1 The Practice of Anesthesiology 1 15 Hypotensive Agents 255 16 Local Anesthetics 263 SECTION Anesthetic Equipment I 17 Adjuncts to Anesthesia 277 & Monitors 2 The Operating Room Environment 9 SECTION III Charles E. Cowles, MD Anesthetic Management 3 Breathing Systems 29 18 Preoperative Assessment, Premedication, 4 The Anesthesia Machine 43 & Perioperative Documentation 295 5 Cardiovascular Monitoring 87 19 Airway Management 309 6 Noncardiovascular Monitoring 123 20 Cardiovascular Physiology & Anesthesia 343 SECTION II 21 Anesthesia for Patients with Clinical Pharmacology Cardiovascular Disease 375 22 Anesthesia for Cardiovascular 7 Pharmacological Principles 143 Surgery 435 8 Inhalation Anesthetics 153 23 Respiratory Physiology & Anesthesia 487 9 Intravenous Anesthetics 175 24 Anesthesia for Patients 10 Analgesic Agents 189 with Respiratory Disease 527 11 Neuromuscular Blocking Agents 199 25 Anesthesia for Thoracic Surgery 545 12 Cholinesterase Inhibitors & Other 26 Neurophysiology & Anesthesia 575 Pharmacologic Antagonists to Neuromuscular Blocking Agents 223 27 Anesthesia for Neurosurgery 593 13 Anticholinergic Drugs 233 28 Anesthesia for Patients with Neurologic & Psychiatric Diseases 613 14 Adrenergic Agonists & Antagonists 239 iii MMoorrgg__FFMM__ii--xxiivv..iinndddd iiiiii 1122//0022//1133 99::4433 AAMM iv CONTENTS 29 Renal Physiology & Anesthesia 631 SECTION Regional Anesthesia & IV 30 Anesthesia for Patients Pain Management with Kidney Disease 653 31 Anesthesia for Genitourinary 45 Spinal, Epidural, & Caudal Blocks 937 Surgery 671 46 Peripheral Nerve Blocks 975 32 Hepatic Physiology & Anesthesia 691 Sarah J. Madison, MD and Brian M. Ilfeld, MD, MS Michael Ramsay, MD, FRCA 47 Chronic Pain Management 1023 33 Anesthesia for Patients with Richard W. Rosenquist, MD and Bruce M. Vrooman, MD Liver Disease 707 Michael Ramsay, MD, FRCA 48 Perioperative Pain Management & Enhanced Outcomes 1087 34 Anesthesia for Patients with Francesco Carli, MD, MPhil and Endocrine Disease 727 Gabriele Baldini, MD, MSc 35 Anesthesia for Patients with Neuromuscular Disease 747 SECTION Perioperative & V 36 Anesthesia for Ophthalmic Critical Care Medicine Surgery 759 37 Anesthesia for Otorhinolaryngologic 49 Management of Patients with Surgery 773 Fluid & Electrolyte Disturbances 1107 38 Anesthesia for Orthopedic Surgery 789 50 Acid–Base Management 1141 Edward R. Mariano, MD, MAS 51 Fluid Management & 39 Anesthesia for Trauma & Blood Component Therapy 1161 Emergency Surgery 805 52 Thermoregulation, Hypothermia, Brian P. McGlinch, MD & Malignant Hyperthermia 1183 40 Maternal & Fetal Physiology 53 Nutrition in Perioperative & Anesthesia 825 & Critical Care 1193 Michael A. Frölich, MD, MS 54 Anesthetic Complications 1199 41 Obstetric Anesthesia 843 Michael A. Frölich, MD, MS 55 Cardiopulmonary Resuscitation 1231 Martin Giesecke, MD and Srikanth Hosur, MBBS, MD 42 Pediatric Anesthesia 877 56 Postanesthesia Care 1257 43 Geriatric Anesthesia 907 57 Critical Care 1277 44 Ambulatory, Nonoperating Room, & Offi ce-Based 58 Safety, Quality, & Performance Anesthesia 919 Improvement 1325 Index 1331 MMoorrgg__FFMM__ii--xxiivv..iinndddd iivv 1122//0022//1133 99::4433 AAMM Chapter Authors Gabriele Baldini, MD, MSc Srikanth Hosur, MBBS, MD Assistant Professor Consultant in Intensive Care Department of Anesthesia QuestCare Intensivists McGill University Dallas, Texas Montreal, Quebec Brian M. Ilfeld, MD, MS John F. Butterworth IV, MD Professor, In Residence Professor and Chairman Department of Anesthesiology Department of Anesthesiology University of California, San Diego Virginia Commonwealth University School of Medicine San Diego, California VCU Health System Richmond, Virginia David C. Mackey, MD Professor Francesco Carli, MD, MPhil Department of Anesthesiology and Professor Perioperative Medicine Department of Anesthesia University of Texas M.D. Anderson Cancer Center McGill University Houston, Texas Montreal, Quebec Sarah J. Madison, MD Charles E. Cowles, Jr, MD Assistant Clinical Professor of Anesthesiology Assistant Professor Department of Anesthesiology Department of Anesthesiology University of California, San Diego and Perioperative Medicine San Diego, California Chief Safety Offi cer Perioperative Enterprise Edward R. Mariano, MD, MAS (Clinical Research) University of Texas MD Anderson Cancer Center Associate Professor of Anesthesia Houston, Texas Stanford University School of Medicine Chief, Anesthesiology and Perioperative Care Service Michael A. Frölich, MD, MS VA Palo Alto Health Care System Associate Professor Palo Alto, California Department of Anesthesiology University of Alabama at Birmingham Brian P. McGlinch, MD Birmingham, Alabama Associate Professor Department of Anesthesiology Martin Giesecke, MD Mayo Clinic M.T. “Pepper” Jenkins Professor in Anesthesiology Rochester, Minnesota Vice Chair, University Hospitals Colonel, United States Army Reserve, Medical Corps Department of Anesthesiology and Pain Management 452 Combat Support Hospital University of Texas Southwestern Medical Center Fort Snelling, Minnesota Dallas, Texas v MMoorrgg__FFMM__ii--xxiivv..iinndddd vv 1122//0022//1133 99::4433 AAMM vi CHAPTER AUTHORS Michael Ramsay, MD, FRCA Bruce M. Vrooman, MD Chairman Department of Anesthesiology Department of Pain Management and Pain Management Anesthesiology Institute Baylor University Medical Center Cleveland Clinic President Baylor Research Institute Cleveland, Ohio Clinical Professor University of Texas Southwestern Medical School John D. Wasnick, MD, MPH Dallas, Texas Steven L. Berk Endowed Chair for Excellence in Medicine Richard W. Rosenquist, MD Professor and Chair Chair, Pain Management Department Department of Anesthesia Anesthesiology Institute Texas Tech University Health Sciences Center Cleveland Clinic School of Medicine Cleveland, Ohio Lubbock, Texas MMoorrgg__FFMM__ii--xxiivv..iinndddd vvii 1122//0022//1133 99::4433 AAMM Contributors Kallol Chaudhuri, MD, PhD Robert Johnston, MD Professor Associate Professor Department of Anesthesia Department of Anesthesia Texas Tech University Health Sciences Center Texas Tech University Health Sciences Center Lubbock, Texas Lubbock, Texas Swapna Chaudhuri, MD, PhD Sanford Littwin, MD Professor Assistant Professor Department of Anesthesia Department of Anesthesiology Texas Tech University Health Sciences Center St. Luke’s Roosevelt Hospital Center and Columbia Lubbock, Texas University College of Physicians and Surgeons New York, New York John Emhardt, MD Department of Anesthesia Alina Nicoara, MD Indiana University School of Medicine Assistant Professor Indianapolis, Indiana Department of Anesthesiology Duke University Medical Center Suzanne N. Escudier, MD Durham, North Carolina Associate Professor Department of Anesthesia Bettina Schmitz, MD, PhD Texas Tech University Health Sciences Center Associate Professor Lubbock, Texas Department of Anesthesia Texas Tech University Health Sciences Center Aschraf N. Farag, MD Lubbock, Texas Assistant Professor Department of Anesthesia Steven L. Shafer, MD Texas Tech University Health Sciences Center Department of Anesthesia Lubbock, Texas Stanford University School of Medicine Palo Alto, California Herbert Gonzalez, MD Assistant Professor Christiane Vogt-Harenkamp, MD, PhD Department of Anesthesia Assistant Professor Texas Tech University Health Sciences Center Department of Anesthesia Lubbock, Texas Texas Tech University Health Sciences Center Lubbock, Texas Kyle Gunnerson, MD Department of Anesthesiology Gary Zaloga, MD VCU School of Medicine Global Medical Aff airs Richmond, Virginia Baxter Healthcare Deerfi eld, Illinois vii MMoorrgg__FFMM__ii--xxiivv..iinndddd vviiii 1122//0022//1133 99::4433 AAMM Research and Review Jacqueline E. Geier, MD Cecilia N. Pena, MD Resident, Department of Anesthesiology Resident, Department of Anesthesiology St. Luke’s Roosevelt Hospital Center Texas Tech University Medical Center Hospital New York, New York Lubbock, Texas Brian Hirsch, MD Charlotte M. Walter, MD Resident, Department of Anesthesiology Resident, Department of Anesthesiology Texas Tech University Medical Center Texas Tech University Medical Center Lubbock, Texas Lubbock, Texas Shane Huff man, MD Karvier Yates, MD Resident, Department of Anesthesiology Resident, Department of Anesthesiology Texas Tech University Medical Center Texas Tech University Medical Center Lubbock, Texas Lubbock, Texas Rahul K. Mishra, MD Resident, Department of Anesthesiology Texas Tech University Medical Center Lubbock, Texas ix MMoorrgg__FFMM__ii--xxiivv..iinndddd iixx 1122//0022//1133 99::4433 AAMM Foreword A little more than 25 years ago, Alexander Kugushev, The fifth edition features three new chapters: then the editor for Lange Medical Publications, Ambulatory, Nonoperating Room, and Office- approached us to consider writing an introduc- based Anesthesia; Perioperative Pain Management tory textbook in the specialty of anesthesiology that and Enhanced Outcomes; and Safety, Quality, and would be part of the popular Lange series of medi- Performance Improvement. There are approxi- cal books. Mr. Kugushev proved to be a convincing mately 70 new figures and 20 new tables. The adop- salesman, in part by off ering his experience with tion of full color dramatically improves the aesthetic scores of authors, all of whom opined that their most appeal of every page. satisfying career achievement was the fathering of However, the biggest and most important their texts. We could not agree more. change in the fifth edition is the “passing of the Now in its fifth edition, the overall stylistic goal baton” to a distinguished and accomplished team of of Clinical Anesthesiology remains unchanged: to be authors and editors. We were thrilled to learn that written simply enough so that a third year medical Drs. Butterworth, Mackey, and Wasnick would be student can understand all essential basic concepts, succeeding us. The result of their hard work proves yet comprehensively enough to provide a strong our enthusiasm was justified as they have taken foundation for a resident in anesthesiology. To quote Clinical Anesthesiology to a new level. We hope you, C. Philip Larson, Jr, MD from the Foreword of the the readers, agree! first edition: “The text is complete; nothing of conse- quence is omitted. The writing style is precise, con- G. Edward Morgan, Jr, MD cise and highly readable.” Maged S. Mikhail, MD xi MMoorrgg__FFMM__ii--xxiivv..iinndddd xxii 1122//0022//1133 99::4433 AAMM

Description:
43 Geriatric Anesthesia 907. 44 Ambulatory, Nonoperating. Room, & Office-Based. Anesthesia 919. SECTION. IV. Regional Anesthesia &. Pain Management. 45 Spinal, Epidural, & Caudal Blocks 937. 46 Peripheral Nerve Blocks 975. Sarah J. Madison, MD and Brian M. Ilfeld, MD, MS. 47 Chronic Pain
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