Table Of Content

Microbial Products Microbial Products: Applications and Translational Trends offers complete coverage of the production of microbial products, including biopolymers, biofuels, bioactive compounds, and their applications in fields such as bioremediation, agriculture, medicine, and other industrial settings. This book focuses on multiple processes including upstream procedures and downstream processing, and the tools required for their production. Lab-scale development processes may not be as efficient when aiming for large-scale industrial production, so it is necessary to utilize in-silico modeling tools such as graph theory and Petri net modeling for bioprocess design to ensure success at translational levels. Therefore, this book presents in-silico and mathematical simulations and approaches used for such applications. Further, it examines microbial products produced from bacteria, fungi, and algae. These major microbial categories have the capacity to produce various diverse second- ary metabolites, bioactive compounds, enzymes, biopolymers, biofuels, probiotics, and more. The bioproducts examined in this book are of great social, medical, and agricultural benefit, and include examples of biodegradable polymers, biofuels, biofertilizers, and drug delivery agents. • Presents approaches and tools that aid in the design of eco-friendly, efficient, and economic bioprocesses. • Utilizes in-silico and mathematical simulations for optimal bioprocess design. • Examines approaches to be used for bioproducts from the lab scale to widely applied microbial biotechnologies. • Presents the latest trends and technologies in production approaches for microbial bioprod- uct manufacture and application. This book is ideal for both researchers and academics, as it provides up-to-date knowledge of applied microbial biotechnology approaches for bioproducts. Microbial Biotechnology for Food, Health, and the Environment Series Series Editor: Ashok Kumar Nadda Plant-Microbial Interactions and Smart Agricultural Biotechnology Edited by Swati Tyagi, Robin Kumar, Baljeet Saharan, Ashok Kumar Nadda Microbial Products Applications and Translational Trends Edited by Mamtesh Singh, Gajendra Pratap Singh, Shivani Tyagi For more information about this series, please visit: www.routledge.com https://www.routledge.com/Microbial-Biotechnology-for-Food-Health-and-the-Environment/ book-series/CRCMBFHE Microbial Products Applications and Translational Trends Edited by Mamtesh Singh Gajendra Pratap Singh Shivani Tyagi Cover image: Dr. Gajendra Pratap Singh First edition published 2023 by CRC Press 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742 and by CRC Press 4 Park Square, Milton Park, Abingdon, Oxon, OX14 4RN CRC Press is an imprint of Taylor & Francis Group, LLC © 2023 selection and editorial matter, Mamtesh Singh, Gajendra Pratap Singh, Shivani Tyagi; individual chapters, the contributors Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, access www.copyright.com or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. For works that are not available on CCC please contact [email protected] Trademark notice: Product or corporate names may be trademarks or registered trademarks and are used only for identification and explanation without intent to infringe. ISBN: 978-1-032-30820-3 (hbk) ISBN: 978-1-032-30839-5 (pbk) ISBN: 978-1-003-30693-1 (ebk) DOI: 10.1201/9781003306931 Typeset in Times by SPi Technologies India Pvt Ltd (Straive) To my late loving father Mr Sher Singh, to whom (along with my mother Mrs Jagroshni) I owe everything I am today and will be. M.S. To my late grandparents and to my parents (Mr Suraj Singh & Mrs Krishna Devi) G.P.S. Contents Preface ...............................................................................................................................................xi Contributors ....................................................................................................................................xiii About the Editors ............................................................................................................................xix PART I Environment Chapter 1 Microbial Products: Applications in the Field of Biotechnology and Bioremediation ...........................................................................................................3 Shalini Porwal, Sonal Chaudhary, Ayushi Singh and Ajit Varma Chapter 2 Microbial Proteases: A Significant Tool for Industrial Applications ........................11 Tanvi Singh, Sushma Sharma and Yamini Tiwari Chapter 3 Microbial Melanin: Role, Biosynthesis, and Applications .......................................25 Sanjay Kumar, Sawraj Singh and Rajeev Kumar Kapoor Chapter 4 Cyanobacteria as Natural Biofactories .....................................................................35 Garvita Singh, Paushali Ghosh, Divya Singh and Jay Kumar Chapter 5 Microbial Production of Polyhydroxyalkanoate from Biological Waste ..................57 Tarika Kumar and Vijay Rayasam Chapter 6 Exopolysaccharides for Heavy Metal Remediation: A Review of Current Trends and Future Prospects ........................................................................73 Anina James, Deepika Yadav and Mohit Kumar Chapter 7 Biosurfactants: A Greener Alternative for a Sustainable Future ...............................85 Neha Dhingra Chapter 8 Biosurfactants: Versatile Molecules with Potential Applications .............................97 Manju Bhaskar and Vinod Kumar Verma Chapter 9 Production of Microbial Enzymes Using Spent Mushroom Compost (SMC) and Its Application ......................................................................109 Anjali Kosre, Deepali, Ashish Kumar and Nagendra Kumar Chandrawanshi vii viii Contents Chapter 10 Indigenous Fermented Food and Beverages of Manipur ........................................119 Vera Yurngamla Kapai, Leisan Judith and Gladys Muivah Chapter 11 Microorganisms in Cosmetology ............................................................................137 Rita Rath, Neeraja Sood and Sadhna Gupta PART II Agriculture Chapter 12 Microbes and Their Products in Sustainable Agriculture .......................................157 Smriti Sharma and Jyotsna Singh Chapter 13 Microbial Biopesticides: An Eco-Friendly Approach for a Sustainable Agro-ecosystem ......................................................................................................189 Nidhi Srivastava, Usha Kumari and Jai Kumar Chapter 14 Application and Impact of Biofertilizers in Sustainable Agriculture .....................205 Sourabh, Nirmal Singh and Preeti Chapter 15 Microbial Endophytes of Medicinal Plants as an Emerging Bioresource for Novel Therapeutic Compounds ..............................................................................235 Ashish Kumar, Rameshwari A. Banjara, Roman Kumar Aneshwari and Nagendra Kumar Chandrawanshi Chapter 16 Utility of Probiotics in Aquaculture ........................................................................249 Reema Mishra, Renu Soni, Preeti Agarwal and Aparajita Mohanty Chapter 17 The Potential Role of Microbes in the Sustainable Growth of Ornamental Fish Culture .........................................................................................273 Archana Aggarwal and Rakhi Gupta Chapter 18 Microbial Metabolites as Fish Immunostimulants: Implications for Aquaculture and Fish Vaccines ...............................................................................293 M. Divya Gnaneswari, Parasuraman Aiya Subramani and Chandrasekaran Binuramesh PART III Medicine Chapter 19 Probiotics for Improving COVID-19 Infection-Linked Microbiome Disparities in Gut ....................................................................................................337 Shivani Tyagi, Divyanshi Chauhan, Aarti Venkatesan and Mamtesh Singh Contents ix Chapter 20 Algal Products in Medicine ....................................................................................345 Neelam Gandhi Chapter 21 Microbial Production and Emerging Applications of Lantibiotics .........................361 Indra Mani, Vijai Singh and Sunil Kumar Chapter 22 Bacterial Drug Delivery Vehicles for Targeted Treatment of Tumors ....................373 Pooja Gulati, Anubhuti Kawatra, Sonika Dhillon and Rakhi Dhankhar Chapter 23 Fungal Products in Medicine ..................................................................................387 Neelam Gandhi Chapter 24 Virosomes: A Drug Delivery System ......................................................................401 Kuntal, Aashita Singh, Twinkle Kathuria, Seema Kalra and Madhu Yashpal Chapter 25 Bioactive Compounds As Potential Remedy Against Coronaviruses .....................417 Kuntal, Prabhleen Kaur, Sakshi Dawer, Madhu Yashpal, Seema Kalra and Archna Chaudhary PART IV In-Silico and Mathematical Tools Chapter 26 Bioinformatics and Vaccine Development: Overview and Prospects .....................435 Swati Bajaj, Pallee Shree and Dileep K. Singh Chapter 27 Petri Net Modeling as an Aid in Bioprocess Designing .........................................455 Gajendra Pratap Singh, Riddhi Jangid and Mamtesh Singh Chapter 28 Applications of Machine Learning in Bioprocess Development and Optimization ...........................................................................................................463 Dharmesh Harwani and Jyoti Lakhani Index ��473