Mechanics of Biomaterials

288 Pages·37.997 MB·English

by  Zadpoor A.A. (Ed.)

Mechanics of Biomaterials
Edited by
Amir A. Zadpoor
Printed Edition of the Special Issue Published in Materials
www.mdpi.com/journal/materials
Amir A. Zadpoor (Ed.)

Mechanics of Biomaterials
This book is a reprint of the special issue that appeared in the online open access
journal Materials (ISSN 1996-1944) in 2015 (available at:
http://www.mdpi.com/journal/materials/special_issues/mechanics-biomaterials).

Guest Editor
Amir A. Zadpoor
Delft University of Technology (TU Delft)
The Netherlands

Editorial Office
MDPI AG
Klybeckstrasse 64
Basel, Switzerland

Publisher
Shu-Kun Lin

Managing Editor
Leo Jiang

1. Edition 2015

MDPI • Basel • Beijing • Wuhan

ISBN 978-3-03842-127-6 (PDF)
ISBN 978-3-03842-128-3 (Hbk)

© 2015 by the authors; licensee MDPI, Basel, Switzerland. All articles in this volume are
Open Access distributed under the Creative Commons Attribution 4.0 license
(http://creativecommons.org/licenses/by/4.0/), which allows users to download, copy and
build upon published articles even for commercial purposes, as long as the author and
publisher are properly credited, which ensures maximum dissemination and a wider impact of
our publications. However, the dissemination and distribution of copies of this book as a
whole is restricted to MDPI, Basel, Switzerland.
III

Table of Contents
List of Contributors ............................................................................................................ VII
About the Guest Editor ....................................................................................................... XII
Preface
Mechanics of Biological Tissues and Biomaterials: Current Trends
Reprinted from: Materials 2015, 8(7), 4505-4511
http://www.mdpi.com/1996-1944/8/7/4505 ....................................................................... XIII
Chapter 1: Mechanics of Biological Tissues
Benjamin Weed, Sourav Patnaik, Mary Rougeau-Browning, Bryn Brazile, Jun Liao,
Raj Prabhu and Lakiesha N. Williams
Experimental Evidence of Mechanical Isotropy in Porcine Lung Parenchyma
Reprinted from: Materials 2015, 8(5), 2454-2466
http://www.mdpi.com/1996-1944/8/5/2454 ............................................................................ 3

Sterling Nesbitt, Wentzell Scott, James Macione and Shiva Kotha
Collagen Fibrils in Skin Orient in the Direction of Applied Uniaxial Load in Proportion to
Stress while Exhibiting Differential Strains around Hair Follicles
Reprinted from: Materials 2015, 8(4), 1841-1857
http://www.mdpi.com/1996-1944/8/4/1841 .......................................................................... 16

Hadi Taghizadeh, Mohammad Tafazzoli-Shadpour, Mohammad B. Shadmehr and
Nasser Fatouraee
Evaluation of Biaxial Mechanical Properties of Aortic Media Based on the Lamellar
Microstructure
Reprinted from: Materials 2015, 8(1), 302-316
http://www.mdpi.com/1996-1944/8/1/302 ............................................................................ 34
Chapter 2: Mechanics of Biomaterials
Wei Li, Tomas Lucioni, Xinyi Guo, Amanda Smelser and Martin Guthold
Highly Stretchable, Biocompatible, Striated Substrate Made from Fugitive Glue
Reprinted from: Materials 2015, 8(6), 3508-3518
http://www.mdpi.com/1996-1944/8/6/3508 .......................................................................... 51
IV

Manfred M. Maurer, Barbara Röhrnbauer, Andrew Feola, Jan Deprest and
Edoardo Mazza
Prosthetic Meshes for Repair of Hernia and Pelvic Organ Prolapse: Comparison of
Biomechanical Properties
Reprinted from: Materials 2015, 8(5), 2794-2808
http://www.mdpi.com/1996-1944/8/5/2794 .......................................................................... 62

Martha Geffers, Jürgen Groll and Uwe Gbureck
Reinforcement Strategies for Load-Bearing Calcium Phosphate Biocements
Reprinted from: Materials 2015, 8(5), 2700-2717
http://www.mdpi.com/1996-1944/8/5/2700 .......................................................................... 77

Hong-Jiang Jiang, Jin Xu, Zhi-Ye Qiu, Xin-Long Ma, Zi-Qiang Zhang, Xun-Xiang Tan,
Yun Cui and Fu-Zhai Cui
Mechanical Properties and Cytocompatibility Improvement of Vertebroplasty PMMA Bone
Cements by Incorporating Mineralized Collagen
Reprinted from: Materials 2015, 8(5), 2616-2634
http://www.mdpi.com/1996-1944/8/5/2616 .......................................................................... 96

Sabine Weiss and Bojan Mitevski
Microstructure and Deformation of Coronary Stents from CoCr-Alloys with Different
Designs
Reprinted from: Materials 2015, 8(5), 2467-2479
http://www.mdpi.com/1996-1944/8/5/2467 ........................................................................ 116

Seyed Mohammad Ahmadi, Saber Amin Yavari, Ruebn Wauthle, Behdad Pouran,
Jan Schrooten, Harrie Weinans and Amir A. Zadpoor
Additively Manufactured Open-Cell Porous Biomaterials Made from Six Different
Space-Filling Unit Cells: The Mechanical and Morphological Properties
Reprinted from: Materials 2015, 8(4), 1871-1896
http://www.mdpi.com/1996-1944/8/4/1871 ........................................................................ 129

Yuqi Teng, Yuqi Zhang, Liping Heng, Xiangfu Meng, Qiaowen Yang and Lei Jiang
Conductive Polymer Porous Film with Tunable Wettability and Adhesion
Reprinted from: Materials 2015, 8(4), 1817-1830
http://www.mdpi.com/1996-1944/8/4/1817 ........................................................................ 156
V

Oihana Moreno-Arotzena, Johann G. Meier, Cristina del Amo and
José Manuel García-Aznar
Characterization of Fibrin and Collagen Gels for Engineering Wound Healing Models
Reprinted from: Materials 2015, 8(4), 1636-1651
http://www.mdpi.com/1996-1944/8/4/1636 ........................................................................ 170

Kai Wang Chan, Hoi Man Wong, Kelvin Wai Kwok Yeung and Sie Chin Tjong
Polypropylene Biocomposites with Boron Nitride and Nanohydroxyapatite Reinforcements
Reprinted from: Materials 2015, 8(3), 992-1008
http://www.mdpi.com/1996-1944/8/3/992 .......................................................................... 186

Juan Wang, Dongsong Li, Tianyi Li, Jianxun Ding, Jianguo Liu, Baosheng Li and
Xuesi Chen
Gelatin Tight-Coated Poly(lactide-co-glycolide) Scaffold Incorporating rhBMP-2 for Bone
Tissue Engineering
Reprinted from: Materials 2015, 8(3), 1009-1026
http://www.mdpi.com/1996-1944/8/3/1009 ........................................................................ 203

Mahmoud Baniasadi and Majid Minary-Jolandan
Alginate-Collagen Fibril Composite Hydrogel
Reprinted from: Materials 2015, 8(2), 799-814
http://www.mdpi.com/1996-1944/8/2/799 .......................................................................... 221

Shengmao Lin and Linxia Gu
Influence of Crosslink Density and Stiffness on Mechanical Properties of Type I
Collagen Gel
Reprinted from: Materials 2015, 8(2), 551-560
http://www.mdpi.com/1996-1944/8/2/551 .......................................................................... 238

Flávia Gonçalves, Ricardo Bentini, Mariana C. Burrows, Ana C. O. Carreira,
Patricia M. Kossugue, Mari C. Sogayar and Luiz H. Catalani
Hybrid Membranes of PLLA/Collagen for Bone Tissue Engineering:
A Comparative Study of Scaffold Production Techniques for Optimal Mechanical Properties
and Osteoinduction Ability
Reprinted from: Materials 2015, 8(2), 408-423
http://www.mdpi.com/1996-1944/8/2/408 .......................................................................... 248

VII

List of Contributors
Seyed Mohammad Ahmadi: Faculty of Mechanical, Maritime and Materials Engineering,
Delft University of Technology (TU Delft), Mekelweg 2, 2628 CD Delft, The Netherlands
Mahmoud Baniasadi: Department of Mechanical Engineering, University of Texas at
Dallas, 800 W. Campbell Rd, Richardson, TX 75080, USA
Ricardo Bentini: Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes,
748, 05508-000 São Paulo, SP, Brazil
Bryn Brazile: Department of Agricultural and Biological Engineering, Mississippi State
University, Starkville, MS 39762, USA
Mariana C. Burrows: Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu
Prestes, 748, 05508-000 São Paulo, SP, Brazil
Ana C. O. Carreira: Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu
Prestes, 748, 05508-000 São Paulo, SP, Brazil; Faculdade de Medicina, Núcleo de Terapia
Celular e Molecular (NUCEL)—Núcleo de Estudos e Terapia Celular e Molecular
(NETCEM), Universidade de São Paulo, Rua Pangaré 100, 05360-130 São Paulo, SP, Brazil
Luiz H. Catalani: Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes,
748, 05508-000 São Paulo, SP, Brazil
Kai Wang Chan: Department of Physics and Materials Science, City University of Hong
Kong, Tat Chee Avenue, Kowloon, Hong Kong
Xuesi Chen: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied
Chemistry, Chinese Academy of Sciences, Changchun 130022, China
Yun Cui: Beijing Allgens Medical Science and Technology Co., Ltd., No. 1 Disheng East
Road, Yizhuang Economic and Technological Development Zone, Beijing 100176, China
Fu-Zhai Cui: School of Materials Science and Engineering, Tsinghua University, Haidian
District, Beijing 100084, China
Cristina del Amo: Multiscale in Mechanical and Biological Engineering (M2BE),
Department of Mechanical Engineering, Aragon Institute of Engineering Research (I3A),
Universidad de Zaragoza, Mariano Esquillor Street, 50018 Zaragoza, Spain
Jan Deprest: Center for Surgical Technologies, Faculty of Medicine, Universitair Ziekenhuis
“Gasthuisberg” Leuven, Katholieke Universiteit Leuven, Leuven 3000, Belgium
Jianxun Ding: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied
Chemistry, Chinese Academy of Sciences, Changchun 130022, China
Nasser Fatouraee: Cardiovascular Engineering Laboratory, Faculty of Biomedical
Engineering, Amirkabir University of Technology, 424 Hafez Ave., Tehran 15875-4413, Iran
Andrew Feola: Center for Surgical Technologies, Faculty of Medicine, Universitair
Ziekenhuis “Gasthuisberg” Leuven, Katholieke Universiteit Leuven, Leuven 3000, Belgium
José Manuel García-Aznar: Multiscale in Mechanical and Biological Engineering (M2BE),
Department of Mechanical Engineering, Aragon Institute of Engineering Research (I3A),
Universidad de Zaragoza, Mariano Esquillor Street, 50018 Zaragoza, Spain
VIII

Uwe Gbureck: Department for Functional Materials in Medicine and Dentistry, University
Hospital Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany
Martha Geffers: Department for Functional Materials in Medicine and Dentistry, University
Hospital Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany
Flávia Gonçalves: Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes,
748, 05508-000 São Paulo, SP, Brazil
Jürgen Groll: Department for Functional Materials in Medicine and Dentistry, University
Hospital Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany
Linxia Gu: Nebraska Center for Materials and Nanoscience, Lincoln, NE 68588-0656, USA
Xinyi Guo: Department of Physics, Wake Forest University, 7507 Reynolda Station,
Winston-Salem, NC 27109, USA
Martin Guthold: Department of Physics, Wake Forest University, 7507 Reynolda Station,
Winston-Salem, NC 27109, USA
Liping Heng: School of Chemistry and Environment, Beihang University, Beijing 100191,
China
Hong-Jiang Jiang: Wendeng Orthopaedic Hospital, No. 1 Fengshan Road, Wendeng
264400, Shandong, China
Lei Jiang: School of Chemistry and Environment, Beihang University, Beijing 100191,
China
Patricia M. Kossugue: Faculdade de Medicina, Núcleo de Terapia Celular e Molecular
(NUCEL)—Núcleo de Estudos e Terapia Celular e Molecular (NETCEM), Universidade de
São Paulo, Rua Pangaré 100, 05360-130 São Paulo, SP, Brazil
Shiva Kotha: Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180,
USA
Baosheng Li: Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University
Cancer Institute and Hospital, Tianjin 300070, China; Department of Radiation Oncology,
Shandong Cancer Hospital, Shandong Academy of Medical Sciences, Jinan 250117, China
Dongsong Li: Department of Orthopaedic Surgery, the First Hospital of Jilin University,
Changchun 130021, China
Tianyi Li: Orthopedics Dept. 2, Heilongjiang Provincial Corps Hospital of Chinese People's
Armed Police Forces, Harbin 150076, China
Wei Li: Department of Physics, Wake Forest University, 7507 Reynolda Station,
Winston-Salem, NC 27109, USA
Jun Liao: Department of Agricultural and Biological Engineering, Mississippi State
University, Starkville, MS 39762, USA
Shengmao Lin: Department of Mechanical and Materials Engineering, University of
Nebraska-Lincoln, Lincoln, NE 68588-0656, USA
Jianguo Liu: Department of Orthopaedic Surgery, the First Hospital of Jilin University,
Changchun 130021, China
Tomas Lucioni: Department of Physics, Wake Forest University, 7507 Reynolda Station,
Winston-Salem, NC 27109, USA
IX

Xin-Long Ma: Tianjin Hospital, No. 406 Jiefang South Road, Tianjin 300211, China
James Macione: Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180,
USA
Manfred M. Maurer: Institute of Mechanical Systems, ETH Zurich, Leonhardstrasse 21,
Zurich 8092, Switzerland
Edoardo Mazza: Institute of Mechanical Systems, ETH Zurich, Leonhardstrasse 21, Zurich
8092, Switzerland; Empa—Swiss Federal Laboratories for Materials Science and
Technology, Überlandstrasse 129, Dübendorf 8600, Switzerland
Johann G. Meier: ITAINNOVA Instituto Tecnológico de Aragón, 7-8 María de Luna Street,
50018 Zaragoza, Spain
Xiangfu Meng: Department of Chemistry, Capital Normal University, Beijing 100048,
China
Majid Minary-Jolandan: Department of Mechanical Engineering, University of Texas at
Dallas, 800 W. Campbell Rd, Richardson, TX 75080, USA
Bojan Mitevski: Brandenburg University of Technology Cottbus-Senftenberg,
Konrad-Wachsmann-Allee 17, Cottbus 03046, Germany
Oihana Moreno-Arotzena: Multiscale in Mechanical and Biological Engineering (M2BE),
Department of Mechanical Engineering, Aragon Institute of Engineering Research (I3A),
Universidad de Zaragoza, Mariano Esquillor Street, 50018 Zaragoza, Spain
Sterling Nesbitt: Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY
12180, USA
Sourav Patnaik: Department of Agricultural and Biological Engineering, Mississippi State
University, Starkville, MS 39762, USA
Behdad Pouran: Faculty of Mechanical, Maritime and Materials Engineering, Delft
University of Technology (TU Delft), Mekelweg 2, 2628 CD Delft, The Netherlands;
Department of Orthopedics and Department of Rheumatology, University Medical Center
Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Raj Prabhu: Department of Agricultural and Biological Engineering, Mississippi State
University, Starkville, MS 39762, USA
Zhi-Ye Qiu: School of Materials Science and Engineering, Tsinghua University, Haidian
District, Beijing 100084, China; Beijing Allgens Medical Science and Technology Co., Ltd.,
No. 1 Disheng East Road, Yizhuang Economic and Technological Development Zone,
Beijing 100176, China
Barbara Röhrnbauer: Institute of Mechanical Systems, ETH Zurich, Leonhardstrasse 21,
Zurich 8092, Switzerland
Mary Rougeau-Browning: Department of Genetics, University of Georgia, Athens, GA
30602, USA
Jan Schrooten : Department of Metallurgy and Materials Engineering, KU Leuven,
Kasteelpark Arenberg 44, PB 2450, 3001 Leuven, Belgium
Wentzell Scott: Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180,
USA