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KEYNOTE ADDRESS: Future of Interventional Cardiology PDF

136 Pages·2015·8.95 MB·English
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ARCH 2015 Keynote Address: The Future of Interventional Cardiology Martin B. Leon, MD Columbia University Medical Center Cardiovascular Research Foundation New York City ARCH 2015 Symposium St. Louis, Missouri; April 10, 2015 Disclosure Statement of Financial Interest ARCH 2015 Symposium; St. Louis, Missouri; April 10, 2015 Martin B. Leon, MD Within the past 12 months, I or my spouse/partner have had a financial interest/arrangement or affiliation with the organization(s) listed below. Affiliation / Financial Relationship Company • Grant / Research Support • Abbott, Boston Scientific, Edwards Lifescience, Medtronic • Consulting Fees / Honoraria • Meril Lifescience, Micell, • Shareholder / Equity • Apica, Claret, Coherex, Elixir, GDS, Medinol, Mitralign, Valve Medical The Future of IC PTCA… The Beginning The Father of PTCA! Andreas Gruentzig 1939 - 1985 His dream was the catheter-based percutaneous treatment of vascular disease in alert, awake patients! Andreas’ Tools Andreas’ Results The Saga of Balloon Angioplasty  Frequent dissections, recoil and poor angiographic outcomes  Acute closure (surgical backup required)  Ineffective in calcified (and other) lesions  RESTENOSIS!!! Not Good Enough! The Future of IC TCT Provokes Change! The 1st TCT - 1988 PURPOSE • Explore a new era of interventional device therapies - innovation! • Re-introduce the live case demonstration format - education • Apply rigorous methods to evaluate devices and clinical outcomes - evidence-based • Create an international network of multi-disciplinary scientists - GLOBAL! The “New Device” Era (1988-1993) • Laser Angioplasty • Atherectomy (directional, rotational, and extraction) • Stents (the early days)

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Laser Angioplasty. • Stents (the early days) .. We are technology addicts (esp. new gizmos which can . GPIIb/IIIa inhibitors (3): Abciximab, Eptifibatide, Tirofiban. IV (±oral) . Catheter-Based Mitral Valve Repair Quantum Cor (RF).
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