Journal of Neuropathology and Experimental Neurology 1997: Vol 56 Table of Contents

9 Pages·1997·2.8 MB·English

Contents of Volume LVI
NUMBER 1, JANUARY, 1997
Methylazoxymethanol Acetate-induced Apoptosis in the External Granule Cell Layer of the Developing Cerebel-
lum of the Rat is Associated with Strong c-Jun Expression and Formation of High Molecular Weight c-Jun
Complexes. IsiDRE FERRER, ESTHER POZAS, MARTA MARTI, ROSA BLANCO, AND ANNA M. PLANAS. Barcelona,
Spain
Immunocytochemical Characterization of the Expression of Inducible and Constitutive Isoforms of Nitric Oxide
Synthase in Demyelinating Multiple Sclerosis Lesions. Cor.ine J. A.D E Groot, PHD, SiGrip R. RuuLs, PHD,
JAN WILLEM M. THEEUWES, BSc, CHRISTINE D. DukstrRA, MD, PHD, AND PAUL VAN DER VALK, MD,
PHD. Amsterdam, The Netherlands .................00.0000000+ soloist 9a 9skeoa uspee al voilarstposansp came mina eee nese afaieioad oni atiay ada
Altered Calcium Homeostasis and Ultrastructure in Motoneurons of Mice Caused by Passively Transferred Anti-
motoneuronal IgG. Jozsrer 1. ENGELHARDT, MD, PHD, LAsz_o SikLos, PHD, AND STANLEY H. APPEL, MD. Szeged,
nr AUN IIE IND oo ss x sisisicic vane w oarnascdicmmeb owed etre ea mamas eka a SRS Oca ea rialenaulane xian isteate Rotauas puneaN a meemon ot
Developmental Regulation of Presenilin mRNA Expression Parallels Notch Expression. OKSANA BEREZOVSKA, PHD,
MENGQ! XIA, MD, PHD, KEITH PAGE, PHD, WILMA Wasco, PHD, RUDOLPH E. TANZI, PHD, AND BRADLEY T. HYMAN,
MD, PHD. Boston, Massachusetts
Exercise Induces Myonuclear Ubiquitination and Apoptosis in Dystrophin-deficient Muscle of Mice. Marco SAn-
DRI, MARZENA PODHORSKA-OKOLOW, VANNA GEROMEL, CORRADO RIZZI, PAOLA ARSLAN, CLAUDIO FRANCESCHI, AND
UGo CARRARO. Wroclaw, Poland and Padova and Modena, Italy
Increased Apoptosis of T Lymphocytes and Macrophages in the Central and Peripheral Nervous Systems of Lewis
Rats with Experimental Autoimmune Encephalomyelitis Treated with Dexamethasone. Kim B. NGUYEN, Pa-
MELA A. MCCOMBE, AND MICHAEL P. PENDER. Brisbane, Australia
Distribution, Levels, and Activity of Glycogen Synthase Kinase-3 in the Alzheimer Disease Brain. JiN-JiNG PEI,
MD, MS, TosHinisA TANAKA, MD, PHD, YUNN-CHYN TUNG, MS, EVA BRAAK, PHD, KHALID IQBAL, PHD, AND INGE
GRUNDKE-IQBAL, PHD. Staten Island, New York and Frankfurt, Germany
Paired Helical Filaments Are Twisted Ribbons Composed of Two Parallel and Aligned Components: Image Re-
construction and Modeling of Filament Structure Using Atomic Force Microscopy. MICHAEL S. POLLANEN,
PHD, PETER MARKIEWICZ, MSc, AND M. CYNTHIA GOH, PHD. Toronto, Ontario, Canada
Bax Protein Expression Is Increased in Alzheimer’s Brain: Correlations with DNA Damage, Bcl-2 Expression,
and Brain Pathology. JosepH H. Su, MD, GANGMIN DENG, PHD, AND CARL W. COTMAN, PHD. Irvine, Cali-
fornia
Preferential Subsarcolemmal Localization of Dystrophin and B-dystroglycan mRNA in Human Skeletal Muscles.
TAKAO Mitsui, MD, HisAomi KAwAI, MD, MASAYUKI SHONO, PHD, MASAKAZU KAWAJIRI, MD, MAKOTO KUNISHIGE,
MD, AND SuHiRO Saito, MD. Tokushima, Japan
Book Reviews
Neurology in Clinical Practice. Walter Bradley, Robert Daroff, Gerald Fenichel, and David Marsden, eds. (JOHN
O. FLEMING, MD)
Biopsy Diagnosis of Peripheral Neuropathy. G. Midroni and J. M. Bilbao. (STEVEN A. Moore, MD, PHD)
Honors
The John Jay Dystel prize for outstanding achievements in Multiple Sclerosis research to Cedric S. Raine. .........
Letters to the Editor
Increasing Brain Tumor Rates: Is There a Link to Aspartame? W. GARY FLAMM, PHD, FACT
Adalbert Koestner, DVM, PhD
NUMBER 2, FEBRUARY, 1997
The Pathobiology of the Oligodendrocyte. SAMUEL K. LUupwin, MBBCH, FRCPC. Kingston, Ontario, Canada
Immunocytochemical Co-localization of the Proteasome in Ubiquitinated Structures in Neurodegenerative Diseases
and the Elderly. Kunio li, MD, PHD, Hiperumi Iro, MD, Kevi TANAKA, MD, AND ASAO HIRANO, MD. Tokushima
and Osaka, Japan and New York, New York
The Subthalamic Nucleus in Parkinson’s Disease and Progressive Supranuclear Palsy. CrAic D. HARDMAN, BSc
(Hons), GLENDA M. HALLIDAY, PHD, DEBORAH A. MCRITCHIE, PHD, AND JOHN G. L. Morris, DM. Westmead and
Randwick, Australia
Microglial Cell Activation in Aging and Alzheimer Disease: Partial Linkage with Neurofibrillary Tangle Burden
in the Hippocampus. Pier Luici DiP4TRE, MD AND BENJAMIN B. GELMAN, MD, PHD. Galveston, Texas
Apoptosis-related Proteins in Skeletal Muscle Fibers of Spinal Muscular Atrophy. Dominiqur S. TEws, MD AND
Hans H. GoreBeL, MD. Mainz, Germany
Prevalence and Disease Associations of Argyrophilic Grains of Braak. P. MARTINEZ-LAGE, MD, PHD AND D. G.
Munoz, FRCP(C). London, Ontario, Canada
The Effects of Additional Pathology on the Cognitive Deficit in Alzheimer Disease. ZSUZSANNA NAGy, MD, DPHIL,
MArGareT M. Esiri, DM, FRCPaTH, Kim A. Jopst, DM, MRCP, JAMes H. Morris, MA, DPHIL, MRCPATH, ELIz-
ABETH M.-F KiNG, BA, RGN, BRENDAN McDONALD, BSc, MB, CHB, MRCPATH, CATHARINE JOACHIM, MD, SUZANNE
LITCHFIELD, BSc, LIN BARNETSON, MA, AND A. DAvip SMITH, DPHIL, Dsc. Oxford, UK
Light and Electron Microscopic Analysis of the Central and Peripheral Nervous Systems of Acid Sphingomyelinase-
deficient Mice Resulting from Gene Targeting. THOMAS ALFRED KUEMMEL, ROLAND SCHROEDER, AND WILHELM
STOFFEL. Cologne, Germany
Amplification and Overexpression of MDM2 in Primary (de novo) Glioblastomas. WojCIECH BIERNAT, MD, PAUL
KLEIHUES, MD, YASUHIRO YONEKAWA, MD, AND HIROKO OHGAKI, PHD. Lyon, France and Zurich, Switzerland
Distinct Neurodevelopmental Patterns of Bcl-2 and Bcl-x Expression Are Altered in Glioneuronal Hamartias of
the Human Temporal Lobe. ANTHONY T. YACHNIS, MD, SUZANNE Z. POWELL, MD, Juby J. OLMSTED, MS, AND
THOMAS A. EsKIN, MD. Gainesville, Florida
Human Fascia Dentata Anatomy and Hippocampal Neuron Densities Differ Depending on the Epileptic Syndrome
and Age at First Seizure. GARY W. MATHERN, MD, PAULA A. KUHLMAN, BS, DELIA MENDOZA, BS, AND JAMEs K.
Pretorius, MS. Los Angeles, California
Letters to the Editor
The Pathogenesis of Alzheimer Disease: An Alternative to the Amyloid Hypothesis (1996;55:1023-—25). WILLIAM I.
ROSENBLUM, MD
ANDREW J. LARNER
a ae OD oc bs wesctrewrevnonedaeuo ncumimaadsnnareevionesecanandinmbasendatavssapeaseeadeotes a
Mark A. SMITH, PHD AND GEORGE PERRY, PHD
NUMBER 3, MARCH, 1997
Developmental Neuropathology and Impact of Perinatal Brain Damage. Il: White Matter Lesions of the Neocortex.
MIGUEL MARIN-PADILLA, MD. Hanover, New Hampshire
Expression of the Homeobox-containing Genes EN/ and EN2 in Human Fetal Midgestational Medulla and Cere-
bellum. Natasa Zec, MD, PHD, Davip H. RowitcH, MD, PHD, Mark J. Bitcoop, BA, AND HANNAH C. KINNEY,
MD. Boston and Cambridge, Massachusetts
Action Potential-generating Cells in Human Glioblastomas. CHARALAMPOS LABRAKAKIS, STEPHAN PATT, MD, PATRICK
WEyDT, JORGE CERVOS-NAVARRO, MD, PHD, REINHARD MEYER, MD, AND HELMUT KETTENMANN, PHD. Berlin and
Jena, Germany
No Evidence for Axonal Atrophy in Human Diabetic Polyneuropathy. JANEAN K. ENGELSTAD, HT, JENNY L. Davies,
BA, CATERINA GIANNINI, MD, PETER C. O’ BrRIEN, PHD, PETER J. Dyck, MD. Rochester, Minnesota
Accumulation of Alzheimer Amyloid-8 Peptide in Cultured Myocytes is Enhanced by Serum and Reduced by
Cerebrospinal Fluid. BoZENA MAZUR-KOLECKA, JANUSZ FRACKOWIAK, RICHARD T. CARROLL, AND HENRYK M. WIs-
NIEWSKI. Staten Island, New York, Crakow, Poland, and Ann Arbor, Michigan
Association of Vascular Amyloid 6 and Cells of the Mononuclear Phagocyte System in Hereditary Cerebral
Hemorrhage with Amyloidosis (Dutch) and Alzheimer Disease. Marion L. C. MAAT-SCHIEMAN, SJOERD G. VAN
DUINEN, ANNEMIEKE J. M. ROZEMULLER, JoostT HAAN, AND RAYMUND A. C. Roos. Leiden and Leiderdorp, Am-
sterdam
Glial-Neuronal Interactions in Alzheimer Disease: Progressive Association of IL-la*+ Microglia and S100B* As-
trocytes with Neurofibrillary Tangle Stages. JIN G. SHENG, MD, RoBert E. MrAk, MD, PHD, AND W. Sue T.
GRIFFIN, PHD. Little Rock, Arkansas and Shanghai, China
Cyclin and Cyclin-Dependent Kinase Expression in Human Astrocytoma Cell Lines. PETER B. Dirks, SHERRI LYNN
HUBBARD, MASAJI MURAKAMI, AND JAMES T. RUTKA. Toronto, Ontario, Canada
Role of Protein Kinase C in Microglia-induced Neurotoxicity in Mesencephalic Cultures. MICHAEL K. MCMILLIAN,
PHD, Petri J. VAINIjOo, MD, AND RaAImMo K. TUOMINEN, MD, PHD. Helsinki, Finland
Distinct Pathological Features of the Gallyas- and Tau-positive Glia in the Parkinsonism-Dementia Complex and
Amyotrophic Lateral Sclerosis of Guam. Kiyomitsu GYANAGI, MD, TAKAO MakiFucHi, MD, TAKASHI OHTOH,
MD, KWANG-MING CHEN, MD, D. CARLETON GAJDUSEK, MD, AND THOMAS N. CHaAsE, MD. Tokyo and Niigata,
Japan and Bethesda, Maryland
Book Reviews
Metabolic and Degenerative Diseases of the Central Nervous System: Pathology, Biochemistry, and Genetics.
Jorge Cervés-Navarro and Henry Urich. (JaMEs M. Powers, MD)
Cancer in the Nervous System. V.A. Levin, ed. (RoDNEY D. McComs, MD)
Free Radicals in Brain Physiology and Disorders. Lester Packer, Midori Hiramatsu, and Toshikazu Yoshikawa,
eds. (LARRY W. OBERLEY)
In Memoriam
Richard Paul Bunge, MD (Gabriele M. Zu Rhein, MD and Ian D. Duncan, BVMS, PhD)
NUMBER 4, APRIL, 1997
The Pathogenesis of Senile Plaques. DENNis W. Dickson, MD. Bronx, New York
Cerebellar Cortex Delayed Maturation in Sudden Infant Death Syndrome. FELIx EFC ruz-SANCHEZ, JOAQUIN LUCENA,
CarLos Ascaso, EDUARDO TOLOSA, LLORENG QUINTO, AND Marco L. Rossi. Barcelona, Spain and Liverpool,
Impact Acceleration Injury in the Rat: Evidence for Focal Axolemmal Change and Related Neurofilament Sidearm
Alteration. J. T. PovLisHock, PHD, A. MARMAROU, PHD, T. McINTosH, PHD, J. Q. TROJANOWSKI, MD, PHD, AND
J. Morot, MD. Philadelphia, Pennsylvania, and Richmond, Virginia
Neurodegeneration of Somatostatin-immunoreactive Neurons in HIV Encephalitis. Laura Fox, BS, MicHAgL AL-
FORD, BA, Cris ACHIM, MD, PHD, MARGARET MALLOory, BS, AND ELIEZER MASLIAH, MD. San Diego and La Joila,
California and Pittsburgh, Pennsylvania
Variant Late Infantile Neuronal Ceroid-lipofuscinosis: Pathology and Biochemistry. J. TyyNELA, J. SUOPANKI, P.
SANTAVUORI, M. BAUMANN, AND M. HALTIA. Helsinki, Finland
Astrocyte-Apolipoprotein E Associations in Senile Plaques in Alzheimer Disease and Vascular Lesions: A Regional
Immunohistochemical Study. Y ANPING SHAO, PHD, MARLA GEARING, PHD, AND SUZANNE S. MIRRA, MD. Atlanta
and Decatur, Georgia
Immunohistochemical Detection of Schwannomin and Neurofibromin in Vestibular Schwannomas, Ependymomas
and Meningiomas. DUONG P. HUYNH, VICTOR MAUTNER, MICHAEL E. BASER, D. STAVROU, AND STEFAN-M.
PuLst. Hamburg, Germany and Los Angeles, California
Quantitative Chromatin Pattern Description in Feulgen-stained Nuclei as a Diagnostic Tool to Characterize the
Oligodendroglial and Astroglial Components in Mixed Oligo-astrocytomas. CHRISTINE DECAESTECKER, PHD, M.
BEATRIZ S. Lopes, MD, LAURENCE GORDOWER, ISABELLE CAMBY, PHD, PATRICK CRAS, MD, JEAN-JACQUES MARTIN,
MD, RosertT Kiss, PHD, Scott R. VANDENBERG, MD, PHD, AND ISABELLE SALMON, MD. Brussels, Belgium and
Charlottesville, Virginia
Clinical and Neuropathological Study of Six Patients with Spastic Paraparesis Associated with HTLV-I: An Ax-
omyelinic Degeneration of the Central Nervous System. Luis M. Cartier, MD, J. GABRIEL CEA, MD, CARMEN
VERGARA, FERNANDO ARAYA, MD, AND PERCY Born, MD. Santiago and Antofagasta, Chile
Relationships between Regional Neuronal Loss and Neurofibrillary Changes in the Hippocampal Formation and
Duration and Severity of Alzheimer Disease. MAcIEJ BoBINSKI, MD, PHD, JERZY WEGIEL, VMD, PHD, MICHAL
TARNAWSKI, MD, MARGARET BoBINSKI, DDS, BARRY REISBERG, MD, Mony J. DE LEON, EDD, DouGLas C. MILLER,
MD, PHD, AND HENRYK M. WISNIEWSKI, MD, PHD. New York and Staten Island, New York
Motor and Sensory Specificity of Host Nerve Axons Influence Nerve Allograft Rejection. RAasiv MipHA, MD, MSc,
FRCS (C), CATHERINE A. MUNRO, Msc, SUSAN E. MACKINNON, MD, FRCS (C), AND LEE C. ANG, MD, FRCP (C). St.
Louis, Missouri and Toronto, Ontario, Canada
Correlation of Endothelin-1 and Transforming Growth Factor B1 with Malignancy and Vascularity in Human
Gliomas. JEFFREY D. STILEs, PHD, PETER T. Ostrow, MD, PHD, Lucia L. BALOos, MD, STEVEN J. GREENBERG, MD,
ROBERT PLUNKETT, MD, WALTER GRAND, MD, AND REID R. HEFFNER, JR., MD. Buffalo, New York
Changes of NMDA Receptor Subunit (NR1, NR2B) and Glutamate Transporter (GLT1) mRNA Expression in
Huntington’s Disease—An In Situ Hybridization Study. THOMAS ARZBERGER, MD, KLAUS KRAMPFL, BSc,
SUSANNE LEIMGRUBER, DMV, ADOLF WEINDL, MD, PHD. Munich, Germany
Books Received
Handbook of Muscle Disease. Russell J. M. Lane, ed. (MICHAEL NoEL HART, MD)
Oppenheimer’s Diagnostic Neuropathology, Second edition. Margaret M. Esiri. (MICHAEL NoEL HART, MD) ...
Book Reviews
Amyotrophic Lateral Sclerosis: Progress and Perspectives in Basic Research and Clinical Applications.
Imaharu Nakano and Asao Hirano, eds. (LARRY W. OBERLEY, PHD)
Atlas of the Human Brainstem. George Paxinos and Xu-Feng Huang. (SHAHRIAR SALAMAT, MD, PHD)
Protocols for Neural Cell Culture, 2nd ed. Sergey Fedoroff and Arleen Richardson, eds. (SEAN MURPHY)
Letter to the Editor
Pathologic Alterations in the Diabetic Neuropathies of Humans. P. J. Dyck and C. Giannini. (ANDERS A. F SIMA,
MD, PHD)
NUMBER 5, MAy, 1997
Transforming Growth Factor a Expression as a Response of Murine Motor Neurons to Axonal Injury and
Mutation-induced Degeneration. FABRiIcE Lisovoski, MD, STEPHANE BLoT, DVM, PHD, CHANTAL LACOMBE, JEAN-
PIERRE BELLIER, PATRICK A. DREYFUS, MD, PHD, AND MARIE-PIERRE JUNIER, PHD. Créteil, France
Frequency of Neuropathological Abnormalities in Very Low Birth Weight Infants. JEFFREY A. GOLDEN, FLOYD H.
GILLES, RAOUL RUDELLI, AND ALAN LEVITON. Boston, Massachusetts, Los Angeles, California, New York, New York,
and Philadelphia, Pennsylvania
Transforming Growth Factor-B1 in Polymyositis and Dermatomyositis Correlates with Fibrosis but not with
Mononuclear Cell Infiltrate. PAOLO CONFALONIERI, MD, PIA BERNASCONI, PHD, FERDINANDO CoRNELIO, MD, AND
RENATO MANTEGAZZA, MD. Milan, Italy
Meningioangiomatosis Is Associated with Neurofibromatosis 2 but not with Somatic Alterations of the NF2 Gene.
ANAT O. STEMMER-RACHAMIMOV, MD, MICHAEL A. HORGAN, MD, ANA LIA TARATUTO, MD, DAvip G. Munoz, MD,
THOMAS W. SmitH, MD, MATTHEW P. Froscu, MD, PHD, AND David N. Louts, MD. Boston, Massachusetts, Portland,
Oregon, Worcester, Massachusetts, Buenos Aires, Argentina, and London, Ontario, Canada
Xenogeneic Adrenal Medulla Graft Rejection Rather Than Survival Leads to Increased Rat Striatal Tyrosine
Hydroxylase Immunoreactivity. MARA BRESJANAC, MD, PHD, JACQUELINE SAGEN, PHD, GAIL SEIGEL, PHD, CARLOS
L. PAINO, PHD, JEFFREY KORDOWER, PHD, AND DON M. GASH, PHD. Ljubljana, Slovenia
Dementia with Lewy Bodies Versus Pure Alzheimer Disease: Differences in Cognition, Neuropathology, Cholin-
ergic Dysfunction, and Synapse Density. WILLIAM SAMUEL, MD, PHD, MICHAEL ALFORD, C. RICHARD HOFSTETTER,
PHD, AND LAWRENCE HANSEN, MD. San Diego, California
Anatomic Relationships of the Human Arcuate Nucleus of the Medulla: A Dil-Labeling Study. Natasa Zec, MD,
PHD, JAMEs J. FILIANO, MD, AND HANNAH C. KINNEY, MD. Boston, Massachusetts and Lebanon, New Hamp-
shire
Aggregation of Mutant Cu/Zn Superoxide Dismutase Proteins in a Culture Model of ALS. H. D. DurHAM, PHD,
J. Roy, BSc, L. DONG, MS, AND D. A. FIGLEwicz, PHD. Montreal, Quebec, Canada and Rochester, New York
The Mean AB Load in the Hippocampus Correlates with Duration and Severity of Dementia in Subgroups of
Alzheimer Disease. Grace T. BARTOO, PHD, David NocHLIN, MD, DoOYONG CHANG, YONGMIN KIM, PHD, AND S.
MARK Sumi, MD. Seattle, Washington
Soluble TNF-a Receptors Are Constitutively Shed and Downregulate Adhesion Molecule Expression in Malignant
Gliomas. THOMAS C. CHEN, MD, PHD, Davin R. Hinton, MD, BriAN D. Sippy, MD, PHD, AND FLORENCE M.
HOFMAN, PHD. Los Angeles, California
Atypical Central Neurocytoma. FIGEN SOYLEMEZOGLU, BERND W. SCHEITHAUER, JACQUES ESTEVE, AND PAUL KLEI-
HUES. Ziirich, Switzerland, Rochester, Minnesota, and Lyon, France
Binding of Malignant Lymphoid Cells to the White Matter of the Human Central Nervous System: Role of
Different CD44 Isoforms, B1, B2 and B7 Integrins, and L-selectin. RitraA AHo, MD, HANNU KALIMo, MD,
Marko SALMI, MD, Davip SmitH, PHD, AND SirPA JALKANEN, MD. Turku, Finland
Book Review
Molecular Mechanisms of Dementia. Wilma Wasco and Rudolph E. Tanzi, eds. (CHRISTINE HULETTE, MD)
Abstracts—73rd Annual Meeting of the American Association of Neuropathologists, Inc. .................................
NUMBER 6, JUNE, 1997
Mast Cell Interactions with the Nervous System: Relationship to Mechanisms of Disease. KEviN C. Dines, PHD
AND HENRY C. PowELL, MD, DSc, FRCPatu. La Jolla, California
High IL-6 and Low IL-10 in the Central Nervous System Are Associated with Protracted Relapsing EAE in DA
Rats. Asim Dias, Jie ZHU, BAO Guo XIAO, MAHA MuSTAFA, AND HANS LINK. Stockholm and Huddinge, Sweden ..
Interleukin (IL)-1B and IL-1B mRNA Expression in Normal and Diseased Skeletal Muscle Assessed by Immu-
nocytochemistry, Immunoblotting and Reverse Transcriptase-nested Polymerase Chain Reaction. LAURENT
BELEC, MD, PHD, FRANCOIS-JEROME AUTHIER, MD, BENEDICTE CHAZAUD, PHD, CECILE PIEDOUILLET, TA, GEORGIA
BARLOVATZ-MEIMON, PHD, AND ROMAIN K. GHERARDI, MD. Paris, France
Multiple Sclerosis: Altered Expression of 70- and 27-kDa Heat Shock Proteins in Lesions and Myelin. DENNis A.
AQuINO, PHD, ELISABETTA CAPELLO, MD, JASON WEISSTEIN, MPH, VIRGINIA SANDERS, PHD, CARMEN Lopez, BS,
WALLACE W. TouRTELLOTTE, MD, PHD, CELIA E BROSNAN, PHD, CeEpric S. RAINE, PHD, DSc, AND WILLIAM T.
Norton, PHD. Bronx, New York and Los Angeles, California
Inhibition of Tyrosine Hydroxylase Expression within the Substantia Nigra of Mice Infected with Canine Dis-
temper Virus. ANNA BENCSIK, PHD, HIDEO AKAOKA, PHD, PASCALE GIRAUDON, PHD, MARIE-FRANCOISE BELIN, PHD,
AND ARLETTE BERNARD, PHD. Lyon, France
The Neuropathology of HIV-infected African Children in Abidjan, Céte d’Ivoire. J. E. BELL, MD, FRCPatH, S.
Lowrik, K. Korri, MD, M. HonpeE, MD, J. ANDOH, MD, K. M. DE Cock, MD, FRCP, DTH&H, Anp S. B. Lucas,
FRCP, FRCPATH. Edinburgh, Scotland
Mice Deficient in All Forms of Lysosomal B-hexosaminidase Show Mucopolysaccharidosis-like Pathology. KiINUKO
SuzuKI, MD, KazuNori SANGO, MD, PHD, RICHARD L. PRoIA, PHD, AND CLARITA LANGAMAN, DDS. Chapel Hill,
North Carolina and Bethesda, Maryland
The Interaction of Growth Rates and Diffusion Coefficients in a Three-dimensional Mathematical Model of Glio-
mas. PATRICIA K. BURGESS, MSc, PAUL M. KULESA, PHD, JAMES D. Murray, DSc, AND ELLSwWoRTH C. ALVoORD,
i I INN oxic are sipsion asinsaienamnp eemaa ee uaa ba Deas Ue ak coum wulaniren maaan ance eae eal aae aaa ata Cues
Laterality in the Histological Effects of Injections of Amyloid-B 25-35 into the Amygdala of Young Fischer Rats.
EINAR M. SIGURDSSON, JOHN M. LEE, XIN -W. DONG, MATTHEW J. HEJNA, AND STANLEY A. LoRENS. Maywood,
Illinois
Cortical Degeneration in Progressive Supranuclear Palsy. A Comparison with Cortical-Basal Ganglionic Degen-
eration. C. BERGERON, MD, M.S. POLLANEN, PHD, L. WEYER, MLT, AND A.E. LANG, MD. Toronto, Ontario,
Canada
Expression of NF2-encoded Merlin and Related ERM Family Proteins in the Human Central Nervous System.
ANAT O. STEMMER-RACHAMIMOYV, CHARO GONZALEZ-AGOSTI, LIN XU, JENNIFER A. BURWICK, ROBERTA BEAUCHAMP,
DENISE PINNEY, DAviD N. Louis, AND VAYA RAMESH. Boston, Massachusetts
Detection of Malignant Cells in Cerebrospinal Fluid Using Fluorescence In Situ Hybridization. RoBert J. vAN
OOSTENBRUGGE, MD, ANTON H. N. HOPMAN, PHD, MARIE H. LENDERS, PETER VAN HEERDE, MD, PHD, JAN-WILLEM
ARENDS, MD, PHD, FRANS C. S. RAMAEKERS, PHD, AND ALBERT TWIJNSTRA, MD, PHD. Maastricht and Amsterdam,
The Netherlands
Books Received
Neurotransmitter Transporters: Structure, Function, and Regulation. Maarten E. A. Reith, ed. (WILLIAM O.
WHETSELL, JR., MD)
The Gaba Receptor. S. J. Enna and B. G. Bowery, eds. (WILLIAM O. WHETSELL, JR., MD)
NUMBER 7, JULY, 1997
Differences between the Pathogenesis of Senile Plaques and Congophilic Angiopathy in Alzheimer Disease. MARCEL
M. VERBEEK, PIET EIKELENBOOM, AND ROBERT M. W. DE WAAL. Nijmegen, The Netherlands. .............2000.0e0eeeee00
In Situ Hybridization Analysis of Girk2 Expression in the Developing Central Nervous System in Normal and
Weaver Mice. JiIANJUN WEI, MD, STEPHEN R. DLOUHY, PHD, SHIRLEY BAYER, PHD, ROBERTO PivA, PHD, TATYANA
VERINA, YI WANG, YUE FENG, BM, BRENDA Dupree, M. E. Hopes, MD, PHD, AND BERNARDINO GHETTI.
MD. Indianapolis, Indiana
High-grade Human Brain Tumors Exhibit Increased Expression of Myelin Transcription Factor 1 (MYT1), a
Zinc Finger DNA-binding Protein. REGINA C. ARMSTRONG, PHD, ALAIN MIGNEAULT, MARYA L. SHEGOG, JIN G.
Kim, PHD, LYNN D. Hupson, PHD, AND RICHARD B. HESSLER, MD. Bethesda, MD
Determination of p53 Mutations, EGFR Overexpression, and Loss of p16 Expression in Pediatric Glioblastomas.
ULRICH SuRE, MD, DaNniELA RUEDI, MS, OSAMU TACHIBANA, MD, YASUHIRO YONEKAWA, MD, HIROKO OHGAKI, PHD,
PAUL KLEIHUES, MD, AND MONIKA E. HEGI, PHD. Zurich, Switzerland
BDNF and TrkB Co-localize in CA1 Neurons Resistant to Transient Forebrain Ischemia in the Adult Gerbil.
IsIDRE FERRER, MD, PHD, Jorpi BALLABRIGA, MD, EULALIA Marti, PHD, ESTHER PozAs, ANNA MARIA PLANAS,
PHD, AND JOAN BLAS!I, PHD. Barcelona, Spain
A Comparison of the Predictive Power for Survival in Gliomas Provided by MIB-1, Bromodeoxyuridine and
Proliferating Cell Nuclear Antigen with Histopathologic and Clinical Parameters. PAuL E. MCKEEveER, MD,
PHD, DonaLp A. Ross, MD, My.a S. STRAWDERMAN, MS, JAMES A. BRUNBERG, MD, HARRY S. GREENBERG, MD,
AND LARRY JUNCK, MD. Ann Arbor, MI
A Novel Splice Site Associated Polymorphism in the Tuberous Sclerosis 2 (TSC2) Gene May Predispose to the
Development of Sporadic Gangliogliomas. MICHAEL PLATTEN, BIRGIT MEYER-PUTTLITZ, INGMAR BLUMCKE, MD,
ANDREAS WAHA, HELMUT K. WoLF, MD, Markus M. NOTHEN, MD, Davip N. Louis, MD, JULIAN R. SAMpson, MD,
AND ANDREAS VON DEIMLING, MD. Bonn and Mainz, Germany, Boston, Massachusetts, and Cardiff, Wales ..........
Heterozygous P, Knockout Mice Develop a Peripheral Neuropathy that Resembles Chronic Inflammatory De-
myelinating Polyneuropathy (CIDP). MicHareL E. SHy, MD, EDGARDO ARROYO, JOHN SLADKY, MD, DANIELA
MENICHELLA, MD, HUIYUAN JIANG, MD, PHD, WeNBO Xu, MD, JOHN KAMHOLZ, MD, PHD, AND STEVEN S. SCHERER,
MD, PHD. Detroit, Michigan, Philadelphia, Pennsylvania, and Atlanta, Georgia
Characterization of Diffuse Axonal Pathology and Selective Hippocampal Damage following Inertial Brain Trau-
ma in the Pig. DouGLAs H. SmitH, MD, XIAO-HAN CHEN, MD, BAI-NAN Xu, MD, Tracy K. McINntTosH, PHD,
THOMAS A. GENNARELLI, MD, AND DAviD EF MEANEY, PHD. Philadelphia, Pennsylvania
Reduced Expression of the P, Form of the Gap Junction Pretein Connexin43 in Malignant Meningiomas. KAzur-
uM! SATO, MD, CATHERINE GRATAS, PHD, JOHANNES LAMPE, MD, WoiJciECH BIERNAT, MD, PAUL KLEIHUES, MD,
HiROSHI YAMASAKI, MSc, PHD, AND HIROKO OHGAKI, PHD. Lyon, France and Zurich, Switzerland
Book Review
Autoimmune Neurologic Disease. Michael P. Pender and Pamela A. McCombe. (MICHAEL NOEL HART, MD) ....
Letter to the Editor
Pathologic Alterations in the Diabetic Neuropathies of Humans. (Response) PETER JAMES Dyck, MD AND CATERINA
GIANNINI, MD
NUMBER 8, AUGUST, 1997
Review of Rett Syndrome. DAWNA DUNCAN ARMSTRONG, MD. Houston, Tex ........0..0ccccccececcecceccecceccncecceccuceceecss
Myofibrillar Myopathy. Lil. Abnormal Expression of Cyclin-dependent Kinases and Nuclear Proteins. SATOSHI
NAKANO, ANDREW G. ENGEL, ICHIRO AKIGUCHI, AND JUN KIMURA. Kyoto, Japan and Rochester, Minnesota
Use of MIB-1 (Ki-67) Immunoreactivity in Differentiating Grade II and Grade III Gliomas. Dora W. Hsu, Davip
N. Louts, Jimmy T. EFIRD, AND E. TESSA HEDLEY-WHYTE. Boston, Massachusetts ...........0.0ccccccceccececcececcecceceecees
4-Hydroxy-2-Nonenal Pyrrole Adducts in Human Neurodegenerative Disease. K. S. MONTINE, P. J. Kim, S. J. OLSON,
W. R. MARKESBERY, AND T. J. MONTINE. Nashville, Tennessee and Lexington, Kentucky
Adenovirus-mediated Wild-type p53 Gene Transfer and Overexpression Induces Apoptosis of Human Glioma
Cells Independent of Endogenous p53 Status. HEwei Li, PHD, HANNS LOCHMULLER, MD, VOON WEE YONG, PHD,
GEORGE KARPATI, MD, AND JOSEPHINE NALBANTOGLU, PHD. Montreal, Quebec, Canada
Loss of Alkaline Phosphatase Activity in Meningiomas: A Rapid Histochemical Technique Indicating Progression-
associated Deletion of a Putative Tumor Suppressor Gene on the Distal Part of the Short Arm of Chromosome
1. ISOLDE NIEDERMAYER, MD, WOLFGANG FEIDEN, MD, WOLFRAM HENN, MD, HEIKE STEILEN-GIMBEL, PHD, WOLF-
INGO STEUDEL, MD, AND KLAus DIETER ZANG, MD. Homburg, Germany
DNA Damage Distribution in the Human Brain as Shown by In Situ End Labeling; Area-specific Differences in
Aging and Alzheimer Disease in the Absence of Apoptotic Morphology. P. J. LucAssSEN, PHD, W. C. J. CHUNG,
MSc, W. KampuHorst, MD, PHD, AND D. E Swaas, MD, PHD. Amsterdam, The Netherlands ..............2.4.+.0000000+:
Glutamate Transporter Alterations in Alzheimer Disease Are Possibly Associated with Abnormal APP Expression.
Sui Li, PHD, MARGARET MALLory, BS, MICHAEL ALFORD, BA, SEIGO TANAKA, PHD, AND ELIEZER MASLIAH, MD. La
Jolla, California
Roie of Vascular Endothelial Growth Factor in Blood-Brain Barrier Breakdown and Angiogenesis in Brain Trau-
ma. SukRiTI NAG, MD, PHD, FRCPC, JenNirer L. TAKAHASHI, BSc, DANIEL W. KiLty, BSc. Toronto, Ontario,
Canada
Amyloid 6-protein (AB) Accumulation in the Leptomeninges during Aging and in Alzheimer Disease. TADANORI
HAMANO, MD, MASAHIRO YOSHIMURA, MD, TSUNEO YAMAZAKI, MD, YASUHISA SHINKAI, MD, KATSUHIKO YANAGI-
SAWA, MD, Masaru KuriyAMA, MD, AND YASUO IHARA, MD. Tokyo, Aichi and Fukui, Japan
Loss of the Presynaptic Vesicle Protein Synaptophysin in Hippocampus Correlates with Cognitive Decline in
Alzheimer Disease. CHUN-I1 Sze, MD, JUAN C. Troncoso, MD, CLaupIA KAwas, MD, PETER Mouton, PHD,
DONALD L. Price, MD, AND LEE J. MARTIN, PHD. Denver, Colorado and Baltimore, Maryland
NUMBER 9, SEPTEMBER, 1997
CADASIL: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy.
MARIE-MAGDELEINE RUCHOUX, MD, PHD, AND CLAUDE-ALAIN MAURAGE, MD. Lille, France
APP.,. Transgenic Mice Develop Age-related AB Deposits and Neuropil Abnormalities, but no Neuronal Loss in
CA1. MICHAEL C. IRIZARRY, MD, MEGAN McNamara, BS, KERRI FEDORCHAK, BS, KAREN Hsiao, MD, PHD, AND
BRADLEY T. HYMAN, MD, PHD. Boston, Massachusetts and Minneapolis, Minnesota
A Neuronal and Neuroanatomical Correlate of HIV-1 Encephalopathy Relative to HIV-1 Encephalitis in HIV-1-
infected Children. ANNA DA CUNHA, DPHIL, MARK MINTZ, MD, LEE E. E1peN, PHD, AND LEROY R. SHARER,
MD. Bethesda, Maryland and Camden and Newark, New Jersey
Disproportionate Loss of CA, Parvalbumin-immunoreactive Interneurons in Patients with Ammon’s Horn Scle-
rosis. ZHEN-QING ZHU, MD, DAWNA L. ARMSTRONG, MD, WINIFRED J. HAMILTON, PHD, AND ROBERT G. GROSSMAN,
NINOS, INI oi occ. ciarsN ipso ncssine Simsw avee rewi niolo spe nicesiaamelestadlersa uesa cted od alee annie de oa eae aE aaa anaes aki ac eee ER eee ise
Detection of p16 Gene Deletions in Gliomas: A Comparison of Fluorescence in Situ Hybridization (FISH) Versus
Quantitative PCR. Arie Perry, MD, TsuToMU Nosor!, PHD, NING Ru, KARI ANDERL, THOMAS J. BORELL, GAYATRY
MOHAPATRA, BurT G. FEUERSTEIN, MD, PHD, RoBerT B. JENKINS, MD, PHD, AND DENNIS A. CARSON, MD. Rochester,
Minnesota and San Diego, La Jolla, and San Francisco, California
Neuronal Expression and Intracellular Localization of Presenilins in Normal and Alzheimer Disease Brains.
DuonGc P. HuyNH, HARRY V. VINTERS, DIANE H. D. Ho, ViINH V. Ho, AND STEFAN-M. Pu cst. Los Angeles,
California
The Loss of GluR2(3) Immunoreactivity Precedes Neurofibrillary Tangle Formation in the Entorhinal Cortex and
Hippocampus of Alzheimer Brains. MiLos D. IkonomMovic, MD, KATsUYOsH! MIZUKAMI, MD, PHD, PETER Davies,
PHD, RONALD HAMILTON, MD, ROXANNE SHEFFIELD, AND DAVID M. ARMSTRONG, PHD. Pittsburgh, Pennsylvania,
Ibaraki, Japan, and Bronx, New York
Dystrophic Axonal Swellings Develop as a Function of Age and Diabetes in Human Dorsal Root Ganglia. ROBERT
E. ScHMipT, DENISE Dorsey, CurTIS A. PARVIN, LucIE N. BEAUDET, SANTIAGO B. PLURAD, AND KEVIN A. ROTH. St.
Louis, Missouri
Predominant Localization of the LIS Family of Gene Products to Cajal-Retzius Cells and Ventricular Neuroepi-
thelium in the Developing Human Cortex. Gary D. CLARK, MD, MASAsHI MizuGuCHI, MD, BARBARA ANTALFFY,
JAMES BARNES, AND DAWNA ARMSTRONG, MD. Houston, Texas and Tochigi, Japan
Myelination Delay in the Cerebral White Matter of Immature Rats with Kaolin-induced Hydrocephalus Is Re-
versible. M. R. DeL BiGio, MD, PHD, FRCPC, J. N. KANFER, PHD, AND Y. W. ZHANG, MD. Manitoba, Winnipeg,
Canada
Book Received
Dementia with Lewy Bodies. Robert Perry, lan McKeith, and Elaine Perry, eds. (MICHAEL NoeEL HART, MD) ....
Book Review
Apoptosis Techniques and Protocols. Judes Poirier, ed. (CAROL K. PeTITO, MD)
News of the American Association of Neuropathologists, Inc.
Erratum
In Memoriam
Meta A. Neumann (ROBERT COHN, MD)
NUMBER 10, OCTOBER, 1997
The Future of Neuroscience—An Ontogeny and Teleology. G.W. BRuUYN. Leiden, The Netherlands
Editorial on Consensus Recommendations for the Postmortem Diagnosis of Alzheimer Disease from the National
Institute on Aging and the Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological
Assessment of Alzheimer Disease. BRADLEY T. HYMAN, MD, PHD, AND JOHN Q. TROJANOWSKI, MD, PHD. Boston,
Massachusetts and Philadelphia, Pennsylvania
Molecular Genetic Evidence for Subtypes of Oligoastrocytomas. DAviD MAINTZ, KLAUS FIEDLER, JENS KOOPMANN,
BRITTA ROLLBROCKER, STEFAN NECHEV, Doris LENARTZ, ARMIN P. STANGL, David N. Louis, JOHANNES SCHRAMM,
Ormar D. WIESTLER, AND ANDREAS VON DEIMLING. Bonn and Cologne, Germany and Boston, Massachusetts .......
Dendritic Translocation of RC3/Neurogranin mRNA in Normal Aging, Alzheimer Disease and Fronto-Temporal
Dementia. JULIA W. CHANG, PHD, Eric SCHUMACHER, BS, PHILLIP M. CouLTER II, MS, Harry V. VINTERS, MD,
AND JOSEPH B. WATSON, PHD. Redwood City and Los Angeles, California
Distribution of Parvalbumin-Immunoreactive Neurons in Brain Correlates with Hippocampal and Temporal Cor-
tical Pathology in Creutzfeldt-Jakob Disease. M. GUENTCHEV, MS, J.-A. HAINFELLNER, MD, G.R. TRABATTONI,
MD, AND H. BupkaA, MD. Wien, Austria
Detection of Chromosomal Changes by Interphase Cytogenetics in Biopsies of Recurrent Astrocytomas and Oli-
godendrogliomas. S.M. Rosso, H. vAN DEKKEN, MD, PHD, K.K. KRISHNADATH, MD, J.C. ALERS, AND J.M. Kros,
ee es IN DIN gc oc cis ce re bnackuenneeancasae de veceminlceddaneaceneeuietitaeuacaGuNoNsuanseeuuesbnsaindoues s
Temporal and Regional Patterns of Axonal Damage following Traumatic Brain Injury: A Beta-amyloid Precursor
Protein Immunocytochemical Study in Rats. HELEN M. BRAMLETT, MS, SUSAN KRAyYDIEH, BS, EDWARD J. GREEN,
PHD, AND W. DALTON DieTRICH, PHD. Miami, Florida
Expression of Telomerase RNA Component Correlates with the MIB-1 Proliferation Index in Ependymomas.
ELISABETH J. RUSHING, MD, Kazuo YASHIMA, MD, DANIEL EF Brown, MD, CHARLES L. Wuite, III, MD, JERRY W.
SHAY, PHD, RICHARD C. RissER, MS, AND Api EF Gazpar, MD. Dallas, Texas
Neuropathological Findings in Eight Children with Cerebro-oculo-facio-skeletal (COFS) Syndrome. Marc R. DEL
Bicio, MD, PHD, FRCPC, CHERYL R. GREENBERG, MD, CM, FRCPC, Lucy B. RorKE, MD, RHONDA SCHNUR, MD,
Donna M. McDoNnALD-McGINN, MSc, AND ELAINE H. ZACKAI, MD. Philadelphia, Pennsylvania and Winnipeg,
Canada
Human Mucopolysaccharidosis IID: Clinical, Biochemical, Morphological and Immunohistochemical Character-
istics. MARGARET Z. JONES, JOSEPH ALROY, JOSEPH C. RUTLEDGE, JOHN W. TAYLOR, ELLSWORTH C. ALVORD, JR.,
JENNIFER TOONE, DEREK APPLEGARTH, JOHN J. Hopwoop, EHUD SKUTELSKY, CHRISTOPHER IANELLI, DAVID THORLEY-
LAWSON, CYNTHIA MITCHELL-HERPOLSHEIMER, ALBERT ARIAS, PETER SHARP, W. EVANS, DAVID SILLENCE, AND KEVIN
T. CAVANAGH. East Lansing, Michigan, Boston, Massachusetts, Seattle and Port Orchard, Washington, Vancouver,
BC, Canada, Adelaide, Westmead and Parametta, Australia, and Tel-Aviv, Israel
Reflections on a Workshop. CLAYTON A. WILEY, MD, PHD.
In Memoriam
Matthew T. Moore (JAMES M. Powers, MD)
NUMBER 11, NOVEMBER, 1997
Molecular Cytogenetics of Brain Tumors. SANDRA H. BIGNER, MD, AND EVELIN SCHROCK, MD. Bethesda, Maryland,
and Durham, North Carolina
Alteration of E-cadherin and Alpha N-catenin Immunoreactivity in the Mouse Spinal Cord following Peripheral
Axotomy. AKIRA SeETO, MD, MitsuHIRO HASEGAWA, MD, PHD, Naoyuki UCHtyAMA, MD, PHD, TeTSUMoRI YA-
MASHIMA, MD, PHD, AND JUNKOH YAMASHITA, MD, PHD. Kanazawa, Japan
Identification of Post-mitotic Oligodendrocytes Incapable of Remyelination within the Demyelinated Adult Spinal
Cord. HAns S. KEIRSTEAD, PHD, AND WILLIAM FE BLAKEMORE, SCD. Cambridge, United Kingdom
Comparison of Two Quantitative Methods for the Evaluation of Neuronal Number in the Frontal Cortex in
Alzheimer Disease. IAN PAUL EvERALL, PHD, MRCPsycu, RICHARD DETERESA, BS, ROBERT TERRY, MD, AND
ELIEZER MASLIAH, MD. London, United Kingdom, and San Diego and La Jolla, California
Pathology of the Central Nervous System in Chester-Erdheim Disease: Report of Three Cases. HOMA ADLE-
BIASSETTE, MD, JEROME CHETRITT, MD, ANNE MARIE BERGEMER-FOUQUET, MD, JANINE WECHSLER, MD, JEAN MARIE
MussIini, MD, AND FRANCOISE GRAY, MD, PHD. Créteil, Nantes, Paris, and Garches, France
Membranous Ultrastructure of Human Arachnoid Cells. MitsuHiIRO HASEGAWA, MD, PHD, TETSUMORI YAMASHIMA,
MD, PHD, SHINYA KipA, MD, PHD, AND JUNKOH YAMASHITA, MD, PHD. Kanazawa, Japan
Apolipoprotein E Accumulates with the Progression of AB Deposition in Transgenic Mice. YUKIFUSA IGETA, MD,
TAKESHI KAWARABAYASHI, MD, PHD, MASAHIRO SATO, PHD, NOBUHIRO YAMADA, MD, PHD, ETsuRO MATSUBARA,
MD, PHD, Kosi IsHiGuro, MD, PHD, Mitsuyasu KANAI, MD, YASUSHI TOMIDOKORO, MD, JuNICHI OsuGA, MD,
PHD, KoicHi OKAMOTO, MD, PHD, SHUNSAKU HiRAI, MD, PHD, AND MIkIo SHOJI, MD, PHD. Gunma, Kanagawa,
and Tokyo, Japan
p53 Mutations versus EGF Receptor Expression in Giant Cell Glioblastomas. AURELIA PERAUD, MD, KUNIHIKO
WATANABE, MD, Kart H. PLATE, MD, YASUHIRO YONEKAWA, MD, PAUL KLEIHUES, MD, AND HIROKO OHGAKI,
PHD. Lyon, France, Zurich, Switzerland, and Freiburg, Germany
Putative Control of Angiogenesis in Hemangioblastomas by the von Hippel-Lindau Tumor Suppressor Gene. REM-
BERT STRATMANN, PHD, MARION KriEG, PHD, RICHARD HAAS, AND KARL H. PLATE, MD. Freiburg, Germany
Decreased Kainate Receptor Binding in the Arcuate Nucleus of the Sudden Infant Death Syndrome. AsHoK
PANIGRAHY, AB, JAMES J. FiLiAno, MD, LYNN A. SLEEPER, SCD, FREDERICK MANDELL, MD, Marie VALDES-DaAPENA,
MD, Henry FE Krous, MD, LuciANA A. RAvA, AB, EDM, W. Frost WHITE, PHD, AND HANNAH C. KINNEY,
MD. Boston and Watertown, Massachusetts, Lebanon, New Hampshire, Miami, Florida, San Diego, California, and
Groton, Connecticut
Axonal Damage Revealed by Accumulation of B-APP in HIV-positive Individuals without AIDS. SHu E An, MD,
PHD, BRUNO GIOMETTO, MD, MIKE Groves, MSc, ROBERT F MILLER, MBBS, FRCP, ANprew A. J. BECKETT, FIBMS,
FRANCOISE GRAY, MD, PHD, BRUNO TAVOLATO, MD, AND FRANCESCO SCARAVILLI, MD, PHD. London, United King-
dom, Padova, Italy, and Créteil, France
NUMBER 12, DECEMBER, 1997
Aging-associated Changes in Human Brain. Ropert E. Mrak, MD, PHD, W. Sue T. GrirFin, PHD, AND Davin I.
GRAHAM, MD, PHD. Little Rock, Arkansas and Glasgow, Scotland, United Kingdom
White Matter Neuronal Heterotopia in Temporal Lobe Epilepsy: A Morphometric and Ir istochemical
Study. JACQUELINE A. Emery, MD, S.N. Roper, MD, AND AMYN M.ROJIANI, MD, PHD. Gainesville, Florida
Expression of Different Isoforms of Nitric Oxide Synthase in Experimentally Denervated and Reinnervated Skel-
etal Muscle. Dominique S. Tews, MD, Hans H. GoeBeL, MD, IMMA SCHNEIDER, MD, ANDREAS GUNKEL, MD,
EBERHARD STENNERT, MD, AND WOLFRAM FE NEIss, MD. Mainz, and Cologne, Germany
BDNF Attenuates Functional and Structural Disorders in Nerves of Galactose-fed Rats. ANDREW P. Mizisin, PHD,
MARYANNE BACHE, PETER S. DISTEFANO, PHD, ANN ACHESON, PHD, RONALD M. LINDSAY, PHD, AND NIGEL A.
CALcuTT, PHD. San Diego and La Jolla, California and Tarrytown, New York
Hydrocephalus in Mice Infected with a Theiler’s Murine Encephalomyelitis Virus Variant. [kKUo TsUNopA, MD,
PHD, INGEBORG J. McCRriGHT, PHD, Li-QING KUANG, MD, ANDREAS ZURBRIGGEN, DVM, PHD, AND Rosert S.
FUJINAMI, PHD. Salt Lake City, Utah and Bern, Switzerland
c-Jun, JNK/SAPK Kinases and Transcription Factor NF-«B Are Selectively Activated in Astrocytes, but not Motor
Neurons, in Amyotrophic Lateral Sclerosis. ANTONIO MIGHELI, MD, PHD, ROBERTO Piva, PHD, CRISTIANA ATZORI,
PHD, Dirk Troost, MD, AND DAVIDE SCHIFFER, MD. Turin, Italy and Amsterdam, The Netherlands ..................-
Spinal Cord Neuropathology in Rat Experimental Autoimmune Encephalomyelitis: Modulation by Oral Admin-
istration of Myelin Basic Protein. PHiLLip G. PopovicH, PHD, JENNY Y. Yu, AND CAROLINE C. WHITACRE,
PHD. Columbus, Ohio
An Immunohistochemical Study of Radial Glial Cells in the Mouse Brain Prenatally Exposed to y-irradiation.
XUE-ZHI SUN, MINORU INOUYE, YOSHIHIRO FUKUI, SETSUJI HISANO, KAZUHIKO SAWADA, HISAKO MURAMATSU, TAKASHI
MurRAMATSU. Nagoya, Japan
Human Telomerase RNA Expression and MIB-1 (Ki-67) Proliferation Index Distinguish He g tomas from
Metastatic Renal Cell Carcinomas. DANIEL EF Brown, MD, Api EF Gazpar, MD, CHaRLeEs L. Wuire, TI, MD,
KAzUO YASHIMA, MD, JERRY W. SHAY, PHD, AND ELISABETH J. RUSHING, MD. Dallas, Texas .............2c0c00ceeeeeeee
The Amyloid B Protein Induces Oxidative Damage of Mitochondrial DNA. PETER BOzNER, MD, PHD, VALENTINA
GRISHKO, PHD, SUSAN P. LEDoux, PHD, GLENN L. WiL_son, PHD, Y-C CYAN, PHD, AND MIGUEL A. PAPPOLLA,
MD. Mobile, Alabama
Diffuse Plaques in the Striatum in Alzheimer Disease (AD): Relationship to the Striatal Mosaic and Selected
Neuropeptide Markers. MARLA GEARING, PHD, ALLAN I. Levey, MD, PHD, AND SUZANNE S. MirRA, MD. Atlanta,
Georgia
Book Received
The Neuropathology of Dementia. Margaret M. Esiri and James H. Morris, eds. (MNH)
Book Review
Fundamental Neuroscience. Duane E. Haines, PhD, ed. (JONATHAN FRATKIN, MD)
Letter to the Editor
Neuropathology: Art and Science. ELLSworRTH C. ALVorD, JR, MD, AND JOSEPH R. SIEBERT, PHD
Author Index
Subject Index