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Journal of Chromatography Biomedical Applications 1993: Vol 618 Index PDF

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Preview Journal of Chromatography Biomedical Applications 1993: Vol 618 Index

Journal of Chromatography Author Index Akiyama, K., see Seki, S. 618(1993)147 Izzo, V., see Duro, G. 618(1993)95 Baba, Y. Jarrett, H. W. Prediction of the behaviour of oligonucleotides in high- Affinity chromatography with nucleic acid polymers performance liquid chromatography and capillary (Review) 618(1993)315 electrophoresis (Review) 618(1993)41 Kasai, K. Barbieri, R., see Duro, G. 618(1993)95 Size-dependent chromatographic separation of nucleic Berardini, M. D., see Hartley, J. A. 618(1993)277 acids (Review) 618(1993)203 Brdicka, R. and Nirnberg, P. Klein, C. B., see Frenkel, K. 618(1993)289 Checking of individuality by DNA profiling (Review) Kroczek, R. A. 618(1993)167 Southern and Northern analysis (Review) 618(1993)133 Bruchelt, G., Niethammer, D. and Schmidt, K. H. Niethammer, D., see Bruchelt, G. 618(1993)57 Isotachophoresis of nucleic acid constituents (Review) Nurnberg, P., see Brdi¢ka, R. 618(1993)167 618(1993)57 Ribeiro, E. A. Cummings, J., French, R. C. and Smyth, J. F. Quantitative analysis of enzymic digests of DNA using Application of high-performance liquid chromatography gel electrophoresis (Review) 618(1993)181 for recognition of covalent nucleic acid modification with Schmidt, K. H., see Bruchelt, G. 618(1993)57 anticancer drugs (Review) 618(1993)251 Seki, S., Akiyama, K., Watanabe, S. and Tsutsui, K. Dawkins, H. J. S., see Townsend, K. M. 618(1993)223 Activity gel and activity blotting methods for detecting Deyl, Z. and Skoda, J. DNA-modifying (repair) enzymes (Review) 618(1993)147 Foreword 618(1993)1 Siems, W. G., see Grune, T. 618(1993)15 Diiring, K. Skoda, J., see Deyl, Z. 618(1993)1 Non-radioactive detection methods for nucleic acids Smyth, J.F., see Cummings, J. 618(1993)251 separated by electrophoresis (Review) 618(1993)105 Souhami, R. L., see Hartley, J. A. 618(1993)277 Duro, G., Izzo, V. and Barbieri, R. Townsend, K. M. and Dawkins, H. J. S. Methods for recovering nucleic acid fragments from Field alternation gel electrophoresis — status quo agarose gels (Review) 618(1993)95 (Review) 618(1993)223 French, R. C., see Cummings, J. 618(1993)251 Tsutsui, K., see Seki, S. 618(1993)147 Frenkel, K. and Klein, C. B. Upcroft, J. A., see Upcroft, P. 618(1993)79 Methods used for analyses of “environmentally” Upcroft, P. and Upcroft, J. A. damaged nucleic acids (Review) 618(1993)289 Comparison of properties of agarose for electrophoresis Grune, T. and Siems, W. G. of DNA (Review) 618(1993)79 Reversed-phase high-performance liquid chromatography Watanabe, S., see Seki, S. 618(1993)147 of purine compounds for investigation of biomedical Werner, A. problems: application to different tissues and body fluids Reversed-phase and ion-pair separations of nucleotides, (Review) 618(1993)15 nucleosides and nucleobases: analysis of biological Hartley, J. A., Souhami, R. L. and Berardini, M. D. samples in health and disease (Review) 618(1993)3 Electrophoretic and chromatographic separation methods used to reveal interstrand crosslinking of nucleic acids (Review) 618(1993)277 Journal of Chromatography List of Compounds Chromatographed Adenine 9,10,20,21,23,25,34-36,60,63,65 Bacillus DNA 232 Adenine-containing compounds 19 Bacterial DNA 214,228 Adenine nucleotides 4,33 Bacteriophage DNA 192 Adenine phosphoribosyltransferase 5 Bacteriophage T4 DNA 87,199 Adenosine 6,9,10,20,21,23,25,26,31,32,34,36,60,61 Bacteriophage T7 DNA 191,195 Adenosine deaminase 5 Bacteriophage T7 DNA, WNsil-digested 195 Adenosine 2’,5’-diphosphate 73 Bacteriophage T7 RNA 112 Adenosine 3’,5’-diphosphate 72,73 Bacteriophage 4 DNA 113,136 Adenosine 2'-monophosphate 65,73 Bacteriophage 4 DNA, structure studies 219 Adenosine 3’-monophosphate 65,73 Bacteriophage pX174 DNA 280 Adenosine kinase 5 Bacteriophage gX174 DNA, Haelll-fragmented 280 Adenosine 3’-phosphate 5’-phosphosulphonate 72 Bacteriophage pXA4 DNA 81 Adenosine 5’-phosphosulphate 73 Base—carcinogen adducts 294 S-Adenosylmethionine 4,6 Bases, modified 308,309 Adenylate kinase 5 Biotin 330 Adenylate nucleotides 22 Biotin-7-dATP 330 Adenylosuccinate lyase 5 Biotin-11-dUTP 330 Adenylosuccinate synthase 5 Biotinylated alkaline phosphatase 113 ADP 9,10,12,20,23,24,26,27,28,30—36,60—62,64,66,71,73,74 Biotinylated DNA 110,111,114 AIDS pathogen 236 Biotinylated DNA, structure studies 126 a-Alanine 63 Biotinylated nucleoside triphosphates 330 B-Alanine 60,61,63,72 Biotinylated nucleotides 109 Alkaline phosphatase—dioxetane system 116 Bis-chloroethylnitrosourea 272 Allantoin 60,63 Bis-chloroethylnitrosourea-DNA adducts 272 Allopurinol 20,63,67,68 N,N-Bis-(2-hydroxyethyl)-2-aminoethanesulphonic acid 63 e-Aminocaproic acid 63 Bleomycin-damaged DNA 157 N?!-2-(2-Aminoethyl)-NAD* 74 Borrelia DNA 232 N°-(6-Aminohexyl)carbamoylmethyl-ATP 74 8-Bromo-NAD* 74 N°-(6-Aminohexyl)carbamoylmethyl-NAD 74 Caffeic acid phenethyl ester 303 5-Aminoimidazolyl ribonucleotide 60 cAMP 61-63 Ammedioi 63 Campylobacter DNA 232 AMP 9,10,12,20,23—28,30—36,60—62,64,69,71,73,74 Candida albicans DNA 244 AMP deaminase 5 Carbamoyl phosphate 60 Aniline 61 Carcinogens, radioactive 290 Anthracyclines 261—265 Caulobacter DNA 232 Anticancer drug-DNA adducts 262,263 cDNA, see Circular DNA Anticancer drug—nucleic acid adducts 254 CDP 12,60-62,74 Antimony 270 CDP-diacylglycerine 4 Antisense DNA 335,336 cGMP 62,63 Antisense RNA 119,335 Chemotherapeutic alkylating agent products 284 Antiviral antibiotics 273 Chlorambucil 271 APEX nuclease 158-162 Chlorambucil-DNA adducts 271,272 Apurinic/apyrimidinic endonuclease 154,158,159,161 Chlorella virus DNA 233 Arabinofuranosylcytosine triphosphate 63 Chlorocyclohexylnitrosourea 272 Aspartate 60 Chlorocyclohexylnitrosourea-DNA adducts 272 Aspartic acid 63 2-Chloroethyl(methylsulphonyl)methanesulphonate, see ATP 4,9,10,20,23,24,26,27—36,60—62,64—66,16, 793—,77 4 Clomesone ATP catabolites 31 N’-(3-Chloro-2-hydroxypropyl)-NAD* 74 ATP/ADP ratio 27,28,30,33-35 Chromosomal DNA 84,227,231 ATP/AMP ratio 27,28,30,33—35 Chromosomal restriction patterns 231 AT-rich fragments 208 Chromosomal sized DNA, see Chromosomes Aval 191,196 Chromosomes 87,90 344 Compound Index Chromosomes from Giardia duodenalis 84,88,90 2,8-Dihydroxyadenine 67 Chromosomes from yeast 88,90 N?,N?-Dimethylguanosine 11 Chromosomes, eucaryotic 87 5,11-Dimethyl-6H-pyrido[4,35]-carbazole, see Ellipticine Circular DNA 88-—90,110,227,236,240,336 1,3-Dimethylxanthine, see Theophylline Circular extra-chromosomal DNA 240 3,7-Dimethylxanthine 63 Circular mammalian DNA 81 Dinucleoside monophosphates, postlabelled 296 Cis-diamminedichloroplatinum, see Cisplatin Direct labelling of DNA with reporter enzyme 112 Cisplatin 266—270 Distamycin derivatives 273 Cisplatin-DNA adducts 253,266—270 Distamycin—DNA adducts 273 Clomesone 273 DNA 95—104,223-249,331,334 Clomesone—DNA adducts 273 DNA adducts 301 Closed circular DNA 81,206 DNA alkylation 257 Closed circular duplex DNA 81 DNA amplification 240,305 Clostridium DNA 232 DNA, Aval-fragmented 196 Clostridium perfringens DNA 232 DNA binding proteins 123—125,220,324,327,329-33 1,333,334 CMP 12,60—62,74 DNA blots 108,133—145,306 Coenzyme A 4 DNA, branched molecules 86 Copper 270 DNA, catenated intertwined dimers 86 Creatinine 61 DNA, chemical hydrolysis 293 Cross-linked oligonucleotides 284 DNA, covalent adducts, see Nucleic acids, covalently modified Cross-linking, purine base pair combinations 281 DNA, cross-linked fragments 280 Cross-linking, pyrimidine base pair combinations 281 DNA, damaged 182,289-314 Cross-links, detection through hybridization 285 DNA, denatured 278,304 Cross-links, cleavage by iron II-EDTA 282 DNA, denatured permanently 284 Cross-links, cleavage by piperidine 281—283 DNA, denatured-renatured 279 Cross-links, see also individual compounds capable of cross- DNA, density distribution in gels 190 link formation 285 DNA-DNA 317 CTP 60-62 DNA-DNA hybrids 331 Cyclophosphamide 270,271 DNA, enzymatic hydrolysis 293,295,297,298,302 Cyclophosphamide—-DNA adducts 271 DNA, enzymatically modified 149 Cystine 67 DNA, enzyme digests 181—201 Cytoadherence gene from Plasmodium falciparum 235 DNA, ethidium bromide staining 185,186,192,198,278,280 Cytosine 63 DNA, extraction methods 293 dADP 12,60 DNA fingerprinting 171 dAMP 12 DNA, fluorescence labelling 192,194,195, see also DNA, dATP 4,60 interaction with fluorescence dyes Daunorubicin 261-265 DNA fragments 90,208,213,216—218,230,305, see also DNA, Daunorubicin—-DNA adducts 261 structure studies dCDP 12,60 DNA fragments, denatured 305 dCMP 12 DNA from human cells 123,199 dCTP 60 DNA hybrids 332 Deoxyadenosine 67 DNA, interaction with fluorescence dyes 186 5'-Deoxy-5-fluorouridine 63,70 DNA intercalators 265 Deoxyguanosine 269,303 DNA, interstrand cross-linking 277-288 dGDP 60 DNA, irradiated 85,185,235 dGMP 12 yDNA, irradiated 198 dGTP 4,60 DNA, isolation 292 Diadenosine 5’,5’’-p'—p*-tetraphosphate 65,66 DNA labelling 109,185 2,6-Diamino-4-hydroxy-5-formamidopyrimidine 296 DNA, length distribution 184,185 N2(2” B,7""-Diaminomitosene- 1’’«-yl)-2’-deoxyguanosine 259 DNA, library screening 336 2,5-Diaziridinyl-1,4-benzoquinone derived cross-links 282 DNA ligase 151,162 Digoxigenin-endlabelled oligonucleotides 124 DNA, linear 86,90,227 Digoxigenin-labelled DNA 111,114,120,123,127 DNA, method of moments (lesions determination) 197 Digoxigenin-labelled nucleotides 110 DNA, methylated 86 Digoxigenin-labelled oligonucleotides 124 DNA methyltransferase 151 Digoxigenin-labelled RNA 119,120 DNA-modifying enzymes 147-166 Compound Index DNA molecules < 50 kb 86 Double-stranded DNA binding proteins 323 DNA molecules > 100 kb 183 Double-stranded DNA fragments 207,208,210,214 DNA molecules several Mb 183 Double-stranded DNA, structure studies 185 DNA molecules lacking free 3’ end 233 Double-stranded polynucleotides 206 DNA molecules lacking free 5’ end 233 Doxorubicin 261—265 DNA, non-denatured 107 Doxorubicin-DNA adducts 253,255,261 ,264,265 DNA, non-radioactively labelled, applications 127-129 Drosophila melanogaster DNA 245 DNA, number average lengths 199 dTDP 12 DNA, pathological changes 239-244 dTMP 12,60 DNA 3’-phosphatase 161 dTTP 60 DNA, photolabelling 111 dUDP 60 DNA, physicochemical properties studied by chromatography dUMP 60 220 Duplex oligonucleotides 281 DNA, *?P-labelled 123,141 Duplex oligonucleotides, endlabelled 281 DNA, point spread function 192 EDTA 69 DNA polymerase 149—156,158,160 Ellipticine 266 DNA, polymerase chain reaction 304 Ellipticine-DNA adducts 266 DNA, polymorphism 90,235,306 Endodeoxyribonuclease 150,152 DNA, postlabelling 296,300—302 Enhancer binding proteins 323 DNA production 336 Enterococcus DNA 228,232 DNA profiling 167-179 Environmental carcinogen—DNA adducts 253 DNA purification 43,292 Episomes 240 DNA, quantitation through charge-coupled devices 188,197 Erythrocyte surface antigen gene 235 DNA, quantitation of fluorescent labels 186 Escherichia coli DNA 229,230,232 DNA, quantitation in gels 187 Escherichia coli K12 genome 230 DNA, quantitation using photostimubale phosphors 189,190 Exonuclease III 158,160,161 DNA, quantitation by X-ray films 189 Extra-chromosomal circular DNA 234 DNA, radioactive batching 279 FAD 4,62 DNA, radioactive labelling 185,186,192 Fluorescein-labelled DNA 115 DNA, random breaks 199 Fluorescence-labelled DNA 114 DNA repair 323 5-Fluorodeoxyuridylate 69 DNA 3’ repair diesterase 151,158,159,161 Fluorouracil 6,63,69 DNA, repaired molecules 182 5-Formamido-4,6-diaminopyrimidine 296 DNA repair enzymes 147-166 5-Formyl-2’-deoxyuridine 296,303 DNA repair proteins 323 N’-Formyl-N-pyruvylurea 294 DNA replication 323 N-Formylurea 294 DNA restriction fragments 210,214 G + C/U + A ratio 71 DNA restriction nuclease digests 191 GDP 9,10,12,20,23,24,26—28 ,30,33—35,61,62,66 DNA restriction nuclease fragments 219 Genomic DNA 135,137 DNA, reversibly renaturing 284 Genomic DNA, enzyme-restricted 136 DNA-RNA duplexes 141 Genomic interstrand cross-links 278 DNA-RNA hybrids 141,143,326 Germanium 270 DNAse 149,153,156,160,162 Giardia chromosomes 90 DNA sequencing 43,90,125—127,304,307,308,335,336 Giardia DNA 233,234 DNA, single-strand breaks 199,278 Giardia duodenalis DNA 233 DNA, size-dependent separations 203—221 Glucuronic acid 1-phosphate 72 DNA, size distribution of digests 196 Glycogen 4 DNA, strand breakages 86 GMP 6,9,10,12,24—28,30,33,36,60—62,66,67 DNA, structure investigation 181—201,334,335 GMP deaminase 5 DNA, structure studies 82,83,86,90,210—214,333, see also GMP synthase 5 DNA fragments, DNA restriction fragments and Double- Gold 270 stranded DNA fragments GTP 4,9,10,20,23,24,26—28,30,31,33-36,60—62,66 DNA, UV light-damaged 199 GTP/GDP ratio 27,28,30,33,35 DNA, weight average, see DNA, number average lengths Guanine 21,32,60,63 Double-stranded DNA 81,108,136,141,143,185,205, Guanine, cross-linked 281 206,207,209,213,280,319,322,323,333 Guanine deaminase 5 346 Compound Index Guanosine 10,20,23,25,34,60,63 1-Methylguanosine 11 Guanylate kinase 5 N?-Methylguanosine 11 Guanylate nucleotides 22 1-Methylhistidine 63 Haell 191,192 3-Methylhistidine 63 Hafnium 270 1-Methylhypoxanthine 68 Halobacterium DNA 232 1-Methylinosine 11 Haloethylnitrosoureas 272 N-la-Methylmitomycin C, see Porfiromycin Heteropolymeric DNAs 318 Methylnitrosourea 271,272 High-Molecular-mass DNA 137 Methylnitrosourea-DNA adducts 271 Hippuric acid 68 4-Methylphenol 72 Histidine 61,63 3-Methylxanthine 63 Histone mRNA 321 Mini-chromosomes 236 Homopolymeric DNAs 318 Mitochondrial DNA 85 Horseradish peroxidase 112 Mitomycin C 257-260 Horseradish peroxidase-labelled DNA 110 Mitomycin C-DNA adduct 258,259 Horseradish peroxidase—luminol system 116 Mitomycin-induced cross-links 281,285 Hpall tiny fragment 237 Mitomycins 256-261 Human leukocyte antigen 237 Molybdenum 270 8-Hydroxy-2’-deoxyguanosine 300,303 C-Myc oncogene-induced cross-linking 286 N-2-Hydroxyethylpiperazine-N’-2-ethanesulphonic acid 63 N-Myc oncogenes 240 N-Hydroxyethylpiperazinepropanesulphonic acid 63 Mycobacterium DNA 232 5-Hydroxymethyl-2’-deoxyuridine 296,303 Mycoplasma DNA 231,232 5-Hydroxy-5-methylhydantoin 294 Myxococcus DNA 232 5-Hydroxymethyluracil 294 NAD 4,9,10,23,26,61,62,69,70 Hypoxanthine 6,9—11,20,21,23,25,31,32,33,35,36,60,63,65,67,68, NADH 23,62,69 70 NADP 23,62,63,71 Hypoxanthine—guanine phosphoribosyltransferase 5 NADPH 23,62,63,71 IDP 62 1-Naphthol 72 IMP 9,10,20,23—28,30—33,36,60,62,66,67 2-Naphthol 72 IMP dehydrogenase 5 Naphthyl glucuronide 66 Inosine 9,10,20,21,23,25,34,35,60,63,65 a-Naphthylamine 61 Interstrand cross-linking repair 286 Neisseria DNA 232 Iridium 270 Neocarzinostatin 273 Iron 270 Neocarcinostatin-DNA adducts 273 Isoluminol-labelled DNA 115 Neuroblastoma DNA 240 ITP 62 Nick translation DNA probes 110 Knob-associated histidine-rich protein 235 Niobium 270 Lactate 69 4-Nitrobluetetrazolium-labelled DNA 115 Large DNA 84,86,87,219,225, see also Chromosomes, Nitrogen mustard 270,271 Chromosomal DNA Nitrogen mustard—-DNA adducts 270,271 Legionella DNA 232 4-Nitrophenol 72,73 Leishmania DNA 233,234 p-Nitrophenol phosphate-labelled DNA 115 Leptospira DNA 232 4-Nitrophenyl sulphate 72 Luminol-labelled DNA 115 Non-platinum organometallics 270 Mycoplasma hominis DNA 232 Non-radioactive labelling 105—131 M. luteus endonuclease 198 Non-specific DNA binding proteins 323,324 Major histocompatibility complex 237 Nsil 191,195 Mammalian DNA 237-244 Nucleases 149 Mass-constrained deconvolution of DNA 192 Nucleic acid constituents 57—77 Mechlorethamine-induced cross-links 286 Nucleic acid fragments 95—104 Melphalan-induced cross-links 280,281 Nucleic acids, as affinity ligands 315-339 Methanesulphonates 273 Nucleic acids, covalently modified 251-276 Methanococcus DNA 232 Nucleic acids, immobilized 315-339 8-Methoxypsoralen-induced cross-links 280 Nucleic acids, interstrand cross-linking 277—288 Methylguanidine 68 Nucleic acids, size-dependent separations 203-221 7-Methylguanine 68 Nucleobases 3—14 Compound Index Nucleoside 3—14,57-77 Poly(A)* RNA 119 Nucleoside diacetates 303 Poly(ADP-ribose) polymerase 151,153 Nucleoside diphosphate kinase 5 Poly(dC) 333 Nucleosides, oxidized 302 Poly(dI) 333 Nucleosides, purine-containing 19 Poly(A)-enriched RNA 210 Nucleoside tricetates 303 3'-Polyadenylic acid 318 Nucleoside triphosphates 67 Polymerase chain reaction of DNA 111 5’-Nucleotidase 5 Polymerase chain reaction products 182 Nucleotides 3—14,57—77 Polynucleotide binding proteins 324,332, see also individual Nucleotide binding proteins 315-339 types of polynucleotides Nucleotides in erythrocytes 24 Polynucleotide phosphorylase 151 Nucleotide monophosphates 7 Polynucleotides 205,209,210,315—339 Nucleotides, oxidized 297 Polynucleotides, short sequences 327 Nucleotides, purine-containing 19 Polyoma virus DNA 81 Nucleotide triphosphates 7 Porfiromycin 260,261 Oligoadenylates 47,63,64,73,74,207,318,321 Porfiromycin-DNA adducts 260 Oligocytidylic acid 318 Primase 149-151 Oligodeoxyadenylates 321,326 Promoter binding proteins 323 Oligoguanylic acid 318 Proteins 213 Oligomeric DNA 325 Pseudomonas DNA 232 Oligonucleotides 41—55,142,208—210,281,282,331,334 Pseudouridine 68 Oligonucleotides, labelling 112 Purine bases 17,57—77 Oligonucleotides, migration prediction 49 Purine compounds 15-40 Oligonucleotides, prediction of behavior 44,47 Purine nucleoside phosphorylase 5 Oligonucleotides, separation by computer simulation 46 Purine nucleosides 17,63 Oligothymidylic acid 318 Purine ribonucleotide 17 Oligouridylic acids 210,318 Pyridine 61 Open circular DNA 81 Pyrimidine (6-4) pyrimidone photoproducts 199 Orotic acid 60,63,68 Pyrimidine bases 57—77 Orotidine 68 Pyrimidine bases, monoadducts 278 Orotidine-5-phosphate 60 Pyrimidine dimers 199 Oxalate 67 Radiolabelled purine precursors 35 8-Oxo-dG:8-hydroxyl(oxo)-2'-deoxyguanosine 296 Random primed labelling of DNA 110,111 Oxypurinol 10,20,63,68 Rat liver DNA 210 32P-Endlabelling 123,279 Recombinant DNA 90 32P_Postlabelled dinucleoside 296 Recombinant proteins 323 Palladium 270 Relaxed circular DNA 227 Parasitic DNA 228 Restriction endonucleotides 323 Pasteurella DNA 230-232 Restriction enzymes, see individual enzymes (abbreviations) pBR322 DNA 279 Restriction fragments of ADNA 216 PCr 69 Restriction site repeats 137 o-Phenylenediamine-labelled DNA 115 Reverse transcriptase 151 Phosphate 67,69 Rhenium 270 3'-Phosphoadenosine-5’-phosphosulphate 71 Rhizobium DNA 232 Phosphorylated purine compounds 15-40 Rhodamine-labelled DNA 115 Phosphorylated compounds 30 Rhodium 270 Plasmid DNA 85,214,280 Ribonuclease 151 Plasmids 214 Ribonucleoside diphosphate reductase 5 Plasmid-sized DNA 90 Ribose-5-phosphate 60 Plasmodium DNA 233-235 Ribose-P-pyrophosphokinase 5 Plasmodium falciparum antigens 235 RNA 333,334 Plasmodium falciparum-specific repetitive DNA element 235 mRNA 112,120,141,143,144,206,210,211,215,323,325,326,331 PM2 DNA 193 rRNA 90.206,207,211,215,229,232 Pneumocystis DNA 233,236 tRNA 68,206,209,211 Poly(A) binding proteins 322 RNA adducts 299 Poly(A) mRNA 321,322,325,328,332 RNA amplification 304 348 Compound Index RNA binding proteins 323 Supercoiled DNA 86,90,227 RNA blots 108,109,133—145 Surface glycoproteins 236 RNA, denatured 107,108 SV40 DNA 193 RNA-DNA heteroduplexes 307 Tamoxifen 303 RNA-DNA hybrids 317 TDP 62 RNA from HeLa cells 142 Terminal deoxynucleotidyl transferase 151 RNA homopolymers 207 12-O-Tetradecanoylphorbol-13-acetate 303 RNA hybrids 332 Texas red-labelled DNA 115 RNA labelling 12,109 Theobromine 63 RNA, non-radioactively labelled, applications 128 Theophylline 63,70 RNA oligomers 319 Thioguanine 6 RNA, photolabelling 111 Thymidine 63 RNA-RNA duplexes 141 Thymidine glycol 303 RNA-RNA mismatches 307 Thymine 63,294 RNA, size-dependent separations 203-221 Thymine dimers 198 RNAse 156 Thymine glycol 294 RNA, small size 215 Tin 270 Ruthenium 270 Titanium 270 Rutheninum—DNA adducts 270 TMP 62 5S DNA 239 Topoisomers of a closed circular DNA 107 23S DNA 215 Transcriptional enhancer/promoter proteins 323 5S RNA 211 Transcription factors 323 16S RNA 215 Transketolase 5 5S rRNA 232,239 Transposition-involved proteins 323 16S rRNA 232 Trypanosoma DNA 233,234,236 S1 Nuclease cleavage products 278 TTP 62 Saccharomyces DNA 244 a-Tubulin gene 234 Salmonella DNA 232 f-Tubulin gene 234 Sarcophytol A 303 UDP 9,10,12,26,61,62,66,71,72 Satellite DNA 170 UDP-N-acetylhexosamine 71 Schizosaccharomyces pombe DNA 244 UDPG 62 Shigella DNA 232 UDP-glucuronic acid 63,66,71 Short DNA sequences 326 UDP-Hex 71 Silver 270 UMP 9,10,12,26,60—62,71,72 Single-stranded breaks 199 Uracil 10,60,63 Single-stranded DNA 110,185,280,319,333,336 Urea 294 Single-stranded DNA binding proteins 323 Uric acid 4,9,10,19-21,25,33,36,60,63,65,67,68,70 Single-stranded polynucleotides 206 Uridine 10,63 Single-stranded RNA 112,336 UTP 9,10,26,60—62,66,71 Small DNA 108 Viral DNA 232 Smearing function 192 VSG genes 236 SP6 RNA 112 Xanthine 9,10,20,21,23,25,29,32,60,63,65,67,68 Specific sequence DNA binding proteins 323 Xanthine oxidase 5 Staphylococcus DNA 229,232 Xanthosine 63,65 Streptavidin 330 XBal 191 Streptavidin—alkaline phosphatase conjugates 113 Yeast chromosomes 87 Streptococcus DNA 232 Yersinia DNA 232 Streptomyces DNA 232 Zirconium 270 Supercoiled circular DNA 234

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