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इंटरनेट मानक Disclosure to Promote the Right To Information Whereas the Parliament of India has set out to provide a practical regime of right to information for citizens to secure access to information under the control of public authorities, in order to promote transparency and accountability in the working of every public authority, and whereas the attached publication of the Bureau of Indian Standards is of particular interest to the public, particularly disadvantaged communities and those engaged in the pursuit of education and knowledge, the attached public safety standard is made available to promote the timely dissemination of this information in an accurate manner to the public. “जान1 का अ+धकार, जी1 का अ+धकार” “प0रा1 को छोड न’ 5 तरफ” Mazdoor Kisan Shakti Sangathan Jawaharlal Nehru “The Right to Information, The Right to Live” “Step Out From the Old to the New” IS 13447 (1992): p-Nitroaniline--Code of Safety. UDC 547.551.54 : 614.8 “!ान $ एक न’ भारत का +नम-ण” Satyanarayan Gangaram Pitroda ““IInnvveenntt aa NNeeww IInnddiiaa UUssiinngg KKnnoowwlleeddggee”” “!ान एक ऐसा खजाना > जो कभी च0राया नहB जा सकता हहहहै””ै” Bhartṛhari—Nītiśatakam “Knowledge is such a treasure which cannot be stolen” '813447:'112 <en '11 £I 'llfiCfi - N-;:f1{C}lQ;;f)f~ ~ m~ Indian Standard p-NITROANILINE - CODE OF SAFETY UDC 547-551·54: 614·8 @ BIS 1992 BUR E A U 0' I N D I AN S TAN DAR D S MANAK BRAVAN. , BAHADUR SHAH ZAPAR MARO NBW DELHI 110002 PrJ.Cro.,. J. ... 1992 Chemical Hazards Sectional Committee, CHn 007 FOREWORD This Indian Standard was adopted by the Bureau of Indian Standards, after the draft finaliz(d by the Chemical Hazards Sectional Committee had been approved by the Chemical Division Council. , p-nitroaniline is used to considerable extent as an intermediate in the preparation of azo and azoic dyes and for the production of p-phenyJene diamine, a rather important, intermediate and dye. p-nitroaniline gets readily absorbed through skin and is a powerful methemoglobin former. In the preparation of this code of safety, considerable assistance has been derived from the following publications: a) Encyclopaedia of chemical technology by Raymond K. Kirk and Donald F. Othmer. b) Dangerous properties of industrial materials - N. Irving Sax seventh edition. c) Occupational health and safety - International Labour Office, Geneva. AMENDMENT NO. 1 MARCH 2002 TO IS 13447: 1992 p-NITROANILINE - CODE OF SAFETY (Page I. clause 4.1.5) - Insert the following new clauses after 4.1.5: '4.1.' U.N. Number-1661. 4.1.' CAS Number - 100-01-6' . ( Page 1. clause 5.1. line 1 ) - Substitute 'TLV (Skin)' for "n. VI. (CHD7) Rcprocraphy Unit. BIS, New Ddhi. India IS 13447 : 1992 Indian Standard p-NITROANILINE - CODE OF SAFETY 1 SCOPE 4.2.2 It is best p,repared by treating p-nitro chlorobenzene WIth excess ammonia under 1.1 This standard describes properties of p pressu~e: It may also be prepared by nitrating nitroaniline, the nature of hazards associated acetanilide to form p-nitroacetanilide (m. p. with it and essential information on personal 214-216°C) and hydrolysing this with caustic protective equipment, storage, handling, label or mineral acid. ling. transportation, spillage and leakage and waste disposal; fire prevention and fire fight 4.2.3 Melting Point '- 148·5°C. ing training and health monitoring, and first 4.2.4 Boiling Point - 332·0:-C. aid. 4.2.5 Relative Density - 1·424. 1.2 This code, however, does not deal with the specifications for design of buildings, process 4.2.6 Vapour Pressure - ] mm at 142·4'.JC. equipment, plant lay-out, storage vessels, 4.2.7 Solubility etc. The code also does not cover the specifications of the rna terial. It is soluble in I 250 parts of cold water 45 parts of boiling water, 20 parts of alcohoi and 2 REFERENCES 22 parts of ether. It is also soluble in benzene methanol a/,'Id mineral acids. ' The following Indian Standards are necessary adjuncts to the standard: 4.3 Chemical Properties IS No. Title 4.3.1 On decomposition, it emits toxic nitrogen dioxide. 4155 : 1966 Glossary of terms relating to chemical and radiation hazar 4.4 Fire and Explosion Hazard Properties dous chemicals 4.4.1 Fire and explosion hazard is slight when 4167 : 1966 Glossary of terms relating to air pollution expose d to heat, flame or mechanical shock. 4.4.2 Flash Point ( Close Cup) - 199°C. 3 TERMINOLOGY For the purpose of this code, the definitions 5 HEALTH EFFECTS AND TOXICITY INFORMATION given in IS 4155 : 1966 and IS 4167 : 1966 shall apply. 5.1 TLV - 3 I11g/1113 4 GENERAL PROPERTIES LDoo oral - rat - 750 rng/kg LDso oral - muss ~ 810 mg/kg 4.1 GenerallnformatioD LD50 oral - guineapig - 450 mg/kg 4.1.1 Common Names - Past Red GG Base. S.2 Routes of Entry-Oral. respiratory and skin. 4.1.2 Chemical Namer - p-nitroaniline, I .. amino- 4-nitrobenzene. S.3 Health Effects 4.1.3 Structural Formula - O,N -<~>-NH,. Acute symptoms of exposure arc flushing of face, headache, nausea, vomiting, weakness, 4.1.4 Molecular Formula - CtlH,N.O:ao increased pulse rate and respiratory rate, instalvity and convulsion. It may induce 4.1.5 Molecular Mass ~ 138. stupor, cynosis and methemoglobinemia. 4.2 Physical Properties 5.3.1 In less acute exposure which has been 4.2.1 Description, Colour and Physical State prolonged over some week~ or months, there is p .. nitroaniline is a bright yellow crystalline usually hemoglobinemia, chronic exposure can material. cause liver damage. IS 13447 : 1992 5.3.1 In less acute exposure which has been 8 SPILLAGE/LEAKAGE AND WASTE prolonged over some weeks or months, there is DISPOSAL usually hemolysis of the red blood cells fol lowed by stimulation of the bone marrow and 8.1 Spillage/Leakage attempts at regeneration. The red cells may show stippling, immature cells may be present. 8.1.1 In case of spillage remove all ignition ~he w~jte blood cells usually show little change sources. either In number morphology. The liver may be affected with production of jaundice. The S.1.2 S~rap up with a nonsparkllng scoop and urine is frequently dark brown or wine pploascael. 1. 0T ha osceo vi,ne vreodlv emd einta lc lecaonn tuapi nsehr ofuolrd duisse coloured. protechv.e e~ulpment. Dispose off the scrap ~y bur~tng In a remote open pit or depositing 6 PERSONAL PROTECTIVE EQUIPMENT In a sanItary landfill. Protective equipments should include protec tive c101hing full face masks with filters for S.l Waste Disposal organic vapours and self contained breathing apparatus or masks with air line supply systems pispose .off ~he collected waste material by may be necessary. Personal protective equip IncmeratlOn In a furnace, there should be arrangement for water washing of floors/area. ment such as gloves. goggles, boots and suit sh()~ld be. ~sed when handling and transporting 9 :It'IRE PREVENTION AND FIRE p-nttroanlhne. FIGHTING 7 STORAGE, HANDLING, LABELLING AND 9.1 Good house keeping and strict adherence TRANSPORT !o all standing orders will avert any mishap 7.1 Storage Involving p-nitroaniline. a) Do not store close to those materials 9.2 To fight fire use water spray or mi~t forml that pose fire or explosion hazard; b) All dry chemical/carbon dioxide extinguishers. room where p-nitroaniline is stored should be essentially flameproof type only. All 10 TRAINING AND HEALTH MONITORING plant and machinery handling p .. nitroanilille shall be effectively earthed for controlling of 10.1 Training undesirable static electricity; and c) Bulk Safety in handling p-nitroaniline depends to a storage areas shoUld be away from all sources of great extent upon the effectiveness of employ open flame, heaters, furnaces and welding or ees education proper safety instructions other flame or spark producing equipments. intelligent supervision and the use of saf~ 'NO SMOKING' signs should be conspicuously equipments. displayed in the area. 10.1 Health MODitorlng 7.2 Handling Provide regular medical monitoring of those Care should be exerci sed while loading and exposed to this material in the work place. It unloading p-nitroaniline by employing carefully is based on blood and urine analysis. Routine instructed and reliable personnel. periodic examinations for each workman should include history, medical observation, 7.3 Labelling blood pressure, pulse, mass and blood and Label indicating -Poison' should be displayed. urine analysis. 7.4 Transport 11 FIRST AID This is classified as class 6.1, that is, Poisonous 11.1 SkiD Contact ( Hazard) Substances. According to UN Classi fication, U. N. No. 1661 such label has to be Wash area of contact with soap and water. If displayed on container s and on vehicle while irritation persists get medical attention. transporting on road. 11.1 Eye Contact 7.4.1 For transport of p-nitroaniline drums of Immediately wash with plenty of water includ approved design and construction as per ing under the eye lids. if irritation persists, instructions laid down with po)ythene liners get medical attention. must be used. 2 Stud.rd Mark The use of tile Standard Mark i. ,ol'erned by the proYi.ioDl of the J1rIr_au 0/1N11. 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HYDERABAD, JAIPUR. KANPUR. LUCKNOW, PATNA. THI RUVANANTHAPU RAM. Printed at Printwell Printe. ... AUluh, India