Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology PDF
Preview Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology
Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology Amit Garg Joseph F. Merola Laura Fitzpatrick Editors Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology Amit Garg • Joseph F. Merola Laura Fitzpatrick Editors Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology Editors Amit Garg Joseph F. Merola Department of Dermatology Department of Dermatology Donald and Barbara Zucker School of Department of Medicine Medicine at Hofstra Northwell Division of Rheumatology Hempstead, NY Inflammation and Immunity USA Brigham and Women’s Hospital Harvard Medical School Laura Fitzpatrick Boston, MA Department of Dermatology USA Donald and Barbara Zucker School of Medicine at Hofstra Northwell Hempstead, NY USA ISBN 978-3-319-18445-6 ISBN 978-3-319-18446-3 (eBook) https://doi.org/10.1007/978-3-319-18446-3 © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland This book was inspired by my late father, Dr. Shankar Lal Garg, who loved rheumatology. He had the great fortune of training with his mentor Dr. John J. Calabro. Thereafter, my father practiced rheumatology for over 45 years in central Massachusetts. What I appreciated most while spending time in his office after school was that his patients adored him, even at a time when health outcomes in rheumatology, in the absence of truly disease modifying treatments, were modest. It was his compassion, kindness, skills, and knowledge which drove this sentiment. My observations in his practice and our dinner table conversations ultimately inspired me to pursue an inter-related focus with the specialty about which he was so passionate. My father was the youngest of nine siblings and grew up in a village on the outskirts of old Delhi. He was accepted into the prestigious All India Institute of Medical Sciences and graduated as one of their Gold Medalists. His elder brother Baghat, the only other sibling with any sort of higher education, sold his scooter to pay for my father’s flight to the United States so that he could pursue their shared dream of him practicing medicine abroad. And Boy, did he! My father practiced rheumatology until he passed in late 2016. One of my most beloved life moments was reacquainting with one of his patients, someone I had first met in his office when I was just 12 years of age. He dropped in while I was cleaning out my father’s office to share stories about his care with my father. I’m certain there were hundreds of patients who had the same cherished experiences, ones I try and build with my own patients each week as a medical dermatologist. A quote by Nelson Mandela resonated with my father, because it aligned with his own personal philosophy in life, and he inspired me to live by it as well. If I can be half as inspiring to my own kids as my father was to me, they will be just fine. There’s no passion to be found in playing small – in settling for a life that is less than the one you are capable of living – Nelson Mandela. Foreword Rheumatic skin diseases are at the core of complex medical dermatology. Drs. Garg, Merola and Fitzpatrick have assembled a group of nationally known dermatologists, rheumatologists and one pulmonologist to deal with these systemic diseases with prominent cutaneous manifestations. Cutaneous manifestations are important clues to rapid and accurate diag- nosis. In addition, cutaneous diseases may complicate therapies directed at control of systemic disease. The approach that is taken in this book is to first approach diagnosis. Over a century ago, Louis A. Duhring stated that “The power of making a correct diagnosis is the key to all success in the treatment of skin diseases; without this faculty, the physician can never be a thorough dermatologist, and therapeutics at once cease to hold their proper position, and become empirical.” The first two chapters speak directly to this issue by first laying out the findings in order to make a correct diagnosis and then detailing the evaluation that is necessary. Subsequently the authors deal with traditional diseases in chapters on lupus, dermatomyositis, scleroderma, pso- riasis and psoriatic arthritis, vasculitis, and sarcoidosis before ending with two chapters on the complications of therapy. The editors and authors have provided the reader with information that will improve diagnostic acumen and should result in improved patient care. Jeffrey P. Callen Professor of Medicine (Dermatology) Chief, Division of Dermatology University of Louisville School of Medicine Louisville, KY, USA vii Preface To my colleagues and all learners of overlap diseases involving the integument: I very much hope you enjoy reading the first edition of our textbook Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology. While there are a number of available sources on this subject area, there are few which exist as consolidated evidence-based inter-disci- plinary summaries. This book was in part inspired by a magnificent predeces- sor of sorts, titled Cutaneous Manifestations of Rheumatic Diseases, by Sontheimer and Provost, with the acknowledgment that our knowledge in this field has evolved significantly over the past two decades. My own personal inspiration was also drawn from experiences with my father, a rheumatolo- gist, about whom I have written in the Dedication. The dynamic nature of new information made it a challenge for us to stay current, even through the initial drafting of content and the editorial process, especially with respect to approval of new treatments (i.e., biologic therapies) and observations of mucocutaneous reactions to novel chemotherapies, for example. We also gave our authors the freedom to write in their own styles as well as some flexibilities in format, with the intent of allowing the experts the ability to relate and emphasize content which flowed naturally for the subject area. This has resulted in some variation in the way the chapters read, some- thing that will likely be better harmonized in a second edition. Despite some of the challenges common to first edition textbooks, this project was a joy to pursue. Joe and Laura were terrific partners in this endeavor. It was a privilege to have one of my mentors and accomplished medical dermatologist, Dr. Jeffrey Callen, write the foreword. For the con- tent, we recruited the very best experts, many of whom are responsible for the primary evidence described in the chapters. I want to extend my deepest grat- itude to all of my aforementioned colleagues for skillfully engaging this project. Nearly all chapters provide an interdisciplinary perspective, one from der- matology, and the other from rheumatology or another related subspecialty, based on the topic. We felt this was a unique and critical value addition to the resource which would facilitate an expanded scope of perspective and prac- tice. The value to dermatologists is derived from knowledge and pearls related to multi-system examinations, workup, and assessments. The value to rheu- matologists and other subspecialists originates from detailed morphologic descriptions or eruptions and dermatologic assessments that will support, and ix x Preface often specify, diagnosis. We are also certain that students of medicine and trainees across medical specialties will find value in the comprehensive multi- disciplinary perspectives that will support disease recognition and early refer- ral or management. Hempstead, NY, USA Amit Garg Contents 1 Evaluation of the Integumentary and Musculokeletal Systems: An Approach to the Interdisciplinary Examination for Overlap Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Mital Patel-Cohen, Amit Garg, Jordan Taylor Said, and Joseph F. Merola 2 Serologic Evaluation in the Rheumatology-D ermatology Overlap Patient . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Anna Helena Jonsson, Marleigh Stern, Alisa N. Femia, and Peter H. Schur 3 Cutaneous Lupus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Lisa Pappas-Taffer, Tania C. Gonzalez-Rivera, and Victoria P. Werth 4 Dermatomyositis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 Matt Lewis, Lorinda Chung, and David Fiorentino 5 Morphea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 Ada Man, M. Kari Connolly, and Robert W. Simms 6 Systemic Sclerosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 Ada Man, M. Kari Connolly, and Robert W. Simms 7 Psoriasis and Psoriatic Arthritis . . . . . . . . . . . . . . . . . . . . . . . . . . 137 Laura Ferris and Soumya Reddy 8 Vasculitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179 Robert G. Micheletti and Peter A. Merkel 9 Sarcoidosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 Misha Rosenbach and Robert P. Baughman 10 Reactive Erythemas and Panniculitides in Connective Tissue Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 Daniel R. Mazori and Alisa N. Femia 11 Iatrogenic Disease and Drug Induced Toxicities Related to Anti-Inflammatory and Immunomodulatory Agents . . . . . . . 271 Shelly Rivas and Allireza Alloo Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 283 xi
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