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Inderbir Singh's Textbook of Human Histology with Colour Atlas and Practical Guide PDF

502 Pages·2014·63.14 MB·English
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Inderbir Singh’s Textbook of Human HisTology Prelim.indd 1 6/21/2014 5:51:08 PM Late Professor Inderbir Singh (1930–2014) Tribute to a Legend Professor Inderbir Singh, a legendary anatomist, is renowned for being a pillar in the education of generations of medical graduates across the globe. He was one of the greatest teachers of his times. He was a passionate writer who poured his soul into his work. His eagle’s eye for details and meticulous way of writing made his books immensely popular amongst students. He managed to become enmeshed in millions of hearts in his lifetime. He was conferred the title of Professor Emeritus by Maharishi Dayanand University, Rohtak. On 12th May 2014, he has been awarded posthomously with Emeritus Teacher Award by National Board of Examination for making invaluable contribution in teaching of Anatomy. This award is given to honour legends who have made tremendous contribution in the field of medical education and their work had vast impact on the education of medical graduates. He was a visionary for his times and the legacies he left behind are his various textbooks on gross anatomy, histology, neuroanatomy, and embryology. Although his mortal frame is not present amongst us, his genius will live on forever. Prelim.indd 2 6/21/2014 5:51:09 PM Inderbir Singh’s Textbook of Human HisTology with Colour atlas and Practical guide Seventh Edition Revised and Edited by nEElam VasuDEVa MBBS MD Director Professor and Head, Department of Anatomy Maulana Azad Medical College, New Delhi saBiTa misHRa MBBS DNB PhD (AIIMS) Professor, Department of Anatomy Maulana Azad Medical College, New Delhi The Health Sciences Publishers New Delhi | London | Philadelphia | Panama Prelim.indd 3 6/21/2014 5:51:10 PM Jaypee Brothers Medical Publishers (P) Ltd Headquarters Jaypee Brothers Medical Publishers (P) Ltd 4838/24, Ansari Road, Daryaganj New Delhi 110 002, India Phone: +91-11-43574357 Fax: +91-11-43574314 Email: Preface Textbook of Human Histology by Professor Inderbir Singh has remained an authoritative and standard textbook for the past many decades and it is our proud privilege to revise this book and bring out the 7th edition. Te strength and popularity of this textbook has been its simple language and comprehensiveness that has essentially remained unchanged since its inception. Professor Singh’s eye for details and his meticulous writing style has always been popular amongst the generations of medical students. Although all the chapters have been revisited and thoroughly revised, we have taken special care to retain the basic essence of the book. To make this standard textbook fulfll the needs of today's generation of students, some new features have been introduced in this edition. A new chapter on Light Microscopy and Tissue Preparation has been added to acquaint the students with the basics of histology. Every student of histology is expected to identify the slides and diferentiate amongst them in a perfect manner. To make the students familiar with the various slides, Histological Plates have been added in each chapter that include a photomicrograph, line drawing, and salient features that are visible while examining under the microscope. Each chapter has been rearranged to provide sequential learning to the students. All the diagrams have been redrawn and many new illustrations have been added for easy comprehension of the basic concepts. Clinical and Pathological Correlations have been added at relevant places for creating an interest of the students in the understanding of pathologies associated with various tissues. For providing an overview of histology to the student and for quick recall, an atlas has been provided at the beginning of the book. Te atlas includes more than 80 slides of histological importance along with their important features. As envisioned by Professor Inderbir Singh, this textbook is of utmost utility not only for the undergraduate students but also for the students pursuing postgraduation in Anatomy. Keeping this in mind, advanced information on various topics has been included as Added Information to cater to the needs of postgraduate students. Te revision of this book was a team efort. We are thankful to our colleagues for their constant encouragement throughout our venture. We extend our heartfelt thanks to our staf in the Histology laboratory for preparing the slides for photography. We are thankful to Dr Sawti Tiwari for her important contribution in drawing some of the fgures. We are grateful to Professor Ivan Damjanov, an esteemed teacher and expert in the feld of pathology well known across the globe, for allowing us to use some of the slides from his collection. We gratefully acknowledge Professor Harsh Mohan, a well known surgical pathologist of India, for providing pathological correlations in the book. We are thankful to Dr Sunayna Misra [M.D (Path.), PGI Chandigarh] for her valuable suggestions and inputs especially in the pathological correlations. Prelim.indd 5 6/21/2014 5:51:10 PM Textbook of Human Histology We extend our heartfelt thanks to Shri Jitendar P Vij (Group Chairman) and Mr Ankit Vij (Group President) for providing us the opportunity to revise Text of Human Histology and for their persistent support in publication of this book. Dr Sakshi Arora (Chief Development Editor), the driving force of this endeavour, deserves a special thanks for her tireless eforts. She has perservered throughout this venture with a smile on her face. We are thankful to her entire development team comprising Dr Mrinalini Bakshi, Dr Swati Sinha, and Ms Nitasha Arora (Editors), and Mr Prabhat Ranjan, Mr Neeraj Choudhary, Mr Ankush Sharma, Mr Phool Kumar, Mr Deep Dogra and Mr Sachin Dhawan (Designers and Operators) for providing insights and creative ideas that helped in polishing this book to best meet the needs of students and faculty alike. We present the 7th edition of this most popular textbook to the medical fraternity as our tribute to a legendary anatomist, Professor Inderbir Singh for being a pillar in the education of generations of doctors throughout the world. Neelam Vasudeva Sabita Mishra vi Prelim.indd 6 6/21/2014 5:51:11 PM Contents Colour Atlas A1–A48 Chapter 1: Light Microscopy and Tissue Preparaton ‰ Components of a light microscope 1 ‰ Principles of a conventional bright feld microscope 3 ‰ Practical tips in using a bright feld microscope 5 ‰ Types of microscopes 5 ‰ Tissue processing 6 ‰ Steps involved in tissue preparation 6 ‰ Steps in tissue processing 7 Chapter 2: Cell Structure ‰ Te cell membrane 8 ‰ Contacts between adjoining cells 13 ‰ Cell organelles 18 ‰ Te cytoskeleton 26 ‰ Te nucleus 28 ‰ Chromosomes 31 Chapter 3: Epithelia ‰ Characteristic features of epithelial tissue 38 ‰ Functions 38 ‰ Classifcation of epithelia 38 ‰ Simple epithelium 39 ‰ Pseudostratifed epithelium 44 ‰ Stratifed epithelium 45 ‰ Basement membrane 51 ‰ Projections from the cell surface 51 Chapter 4: Glands ‰ Classifcation of glands 55 ‰ Classifcation of exocrine glands 55 ‰ Structural organisation 59 ‰ Development of glands 60 Prelim.indd 7 6/21/2014 5:51:11 PM Textbook of Human Histology Chapter 5: General Connectve Tissue ‰ Fibres of connective tissue 61 ‰ Cells of connective tissue 66 ‰ Intercellular ground substance of connective tissue 71 ‰ Diferent forms of connective tissue 72 ‰ Summary of the functions of connective tissue 78 Chapter 6: Cartlage ‰ General features of cartilage 80 ‰ Components of cartilage 81 ‰ Types of cartilage 82 Chapter 7: Bone ‰ General features 87 ‰ Te periosteum 88 ‰ Elements comprising bone tissue 89 ‰ Types of bone 92 ‰ Formation of bone 98 ‰ How bones grow 102 Chapter 8: Muscular Tissue ‰ Types of muscular tissue 107 ‰ Skeletal muscle 108 ‰ Cardiac muscle 120 ‰ Smooth muscle 122 ‰ Myoepithelial cells 126 Chapter 9: Lymphatcs and Lymphoid Tissue ‰ Lymphatic vessel 127 ‰ Lymphoid tissue 127 ‰ Lymph 128 ‰ Lymphocytes 128 ‰ Lymphatic vessels 130 ‰ Lymph capillaries 130 ‰ Larger lymph vessels 130 ‰ Lymph nodes 131 ‰ Te spleen 134 ‰ Te thymus 138 ‰ Mucosa-associated lymphoid tissue 142 ‰ Tonsils 143 viii Prelim.indd 8 6/21/2014 5:51:11 PM Contents Chapter 10: The Blood and the Mononuclear Phagocyte System ‰ Te plasma 145 ‰ Cellular elements of blood 145 ‰ Erythrocytes (red blood corpuscles) 145 ‰ Leucocytes (white blood corpuscles) 147 ‰ Blood platelets 154 ‰ Formation of blood (haemopoiesis) 155 ‰ Mononuclear phagocyte system 158 Chapter 11: Nervous System ‰ Tissues constituting the nervous system 162 ‰ Structure of a neuron 163 ‰ Types of neurons 168 ‰ Peripheral nerves 169 ‰ Neuroglia 172 ‰ Te synapse 175 ‰ Ganglia 17 ‰ Spinal cord; cerebellar cortex; cerebral cortex 180 Chapter 12: Skin and its Appendages ‰ Skin 191 ‰ Types of skin 191 ‰ Structure of skin 191 ‰ Blood supply of the skin 199 ‰ Nerve supply of the skin 199 ‰ Functions of the skin 199 ‰ Appendages of the skin 200 ‰ Hair 20 ‰ Sebaceous glands 204 ‰ Sweat glands 205 ‰ Nails 207 Chapter 13: The Cardiovascular System ‰ Endothelium 210 ‰ Arteries 21 ‰ Arterioles 216 ‰ Capilaries 216 ‰ Sinusoids 218 ‰ Veins 218 ‰ Venules 219 ‰ Blood vessels, lymphatics and nerves supplying blood vessels 221 ‰ Mechanisms controlling blood fow through the capillary bed 221 ‰ Te heart 223 ix Prelim.indd 9 6/21/2014 5:51:11 PM

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