Final Report nd 2 African Regional Conference on Immunization (ARCI) Ouagadougou, Burkina Faso 06 - 08 December 2010 Contents Page Abbreviations……………………………………………………………………………... 3 Executive Summary of Conference Outcomes…………………………………………..5 Summary of outcomes……………..……………………………………………………...5 Polio Eradication……………………………………………………………………. 5 Reaching Un/Under-Immunized Children in the African Region………………… 6 Accelerated Disease Control Initiatives in the African Region……………………... 7 Session 1: Opening Ceremony…........................................................................................ 9 Session 2: Polio Eradication……………………………………………………………… 11 Parallel session: Interrupting endemic & re-established transmission…………. 14 Parallel session: Preventing new international spread & outbreaks……………. 16 Session 3: Reducing number of un /under-immunized children ……………………… 20 Parallel session: Routine immunization………………………………………… 26 Parallel session: New vaccines…………………………………………………. 30 Parallel session: Immunization Financing……………………………………… 35 Session 4: Accelerated Disease Control Initiative in the African Region……………... 38 Session 5: Closing Ceremony…………………………………………………………….. 45 Annexes 1. List of Participants ……………………………………………………………………… 47 2 Abbreviations ACPE Advisory Committee on Poliomyelitis Eradication AFP Acute Flaccid Paralysis ARCC African Regional Certification Commission ARCI Annual Regional Conference on Immunization BMGF Bill and Melinda Gates Foundation bOPV bivalent Oral Polio Vaccine CDC Centers for Disease Control and Prevention cVDP circulating Vaccine-Derived Poliovirus DoV Decade of Vaccines EPI Expanded Programme on Immunization EU European Union FRR Financial Resource Requirements GAP.III Third edition of the Global Action Plan to minimize post eradication poliovirus facility-associated risk GIVS Global Immunization Vision and Strategy GPEI Global Polio Eradication Initiative GPLN Global Polio Laboratory Network GPMT Global Polio Management Team ICC Interagency Coordinating Committee IPD Immunization Plus Day IST Intercountry Support Team iVDPV Immunodeficiency-Associated Vaccine-Derived Poliovirus JSI John Snow Incorporated LGA Local Government Area 3 LQAS Lot Quality Assurance Sampling MDGs Millennium Development Goals mOPV Monovalent Oral Polio Vaccine NGO Non Governmental Organization NID National Immunization Day OPV Oral Polio Vaccine PCV Pneumococcal Conjugate Vaccine RED Reaching Every District SAGE Strategic Advisory Group of Experts on Immunization SIA Supplementary Immunization Activity SIAD Short Interval Additional Dose SNID Sub-National Immunization Day TAG Technical Advisory Group tOPV trivalent Oral Polio Vaccine UNICEF United Nations International Children Emergency Fund VAPP Vaccine-Associated Paralytic Polio VDPV Vaccine -Derived Poliovirus VPD Vaccine-Preventable Disease WHA World Health Assembly WHO World Health Organization WPV Wild Poliovirus 4 Executive Summary of Conference Outcomes The second African Regional Conference on Immunisation was convened in Ouagadougou, Burkina Faso from 6 to 8 December 2010. The conference was officially opened by the Prime Minister His Excellency Mr. Tertius Zongo, in the presence of the chairman of the 60th Session of the Regional Committee the Honourable Minister of Health from Equatorial Guinea, the Minister of Health for Burkina Faso, WHO Director General, the President of the Global Health Program of the Bill and Melinda Gates Foundation, WHO Regional Director for Africa, the Acting CEO of GAVI, Parliamentarians from DR Congo and Cameroun, Traditional Leaders from Nigeria, National EPI programme managers, UN agencies, immunization partners, donors, and TFI members. Three core themes on immunization in Africa were thoroughly reviewed and discussed and the main outcomes are highlighted below: (1) Polio Eradication: The conference commended Nigeria for the significant progress made in reducing wild poliovirus (WPV) cases. The meeting also recognised the efforts made by Chad and the importation countries in West Africa in limiting the circulation of WPV. Concerns were however raised with continued circulation of WPV in DR Congo and Angola, the outbreak in Congo Brazzaville affecting mostly adults and the poor surveillance in Kenya/Uganda border and East DR Congo evidenced by missed circulation of WPV (orphan viruses). The conference proposed the following actions: 1. The conference commended the coordination efforts in West Africa by WHO, UNICEF and countries and requested that this model be adopted in all countries and sub regions experiencing polio outbreaks. 2. The conference recognized the institutionalization of Independent Monitoring (IM) in Polio SIA and the use of the generated data in tracking progress towards achieving the global polio eradication milestones. The conference called upon WHO and partners to support countries fully implement corrective measures whenever shortcomings in SIA quality are identified through IM. 3. Recognizing the high level advocacy that lead to the development of the 6-months Polio Emergency Plan currently being implemented, the conference called upon Angola to review and intensify implementation in 2011 4. The conference noted with concern the intense transmission of WPV in DR Congo and urged the country to urgently develop and implement an Emergency Plan to address chronic SIA gaps and sub-national surveillance weaknesses. Additionally, WHO should provide technical assistance to improve the performance of the National Polio Laboratory in DR Congo 5 5. Nigeria and Chad should develop and implement aggressive mop ups strategies to reach high risk areas, migrant and mobile populations in order to interrupt transmission in line with the set milestones. 6. Countries with the support from partners should develop a comprehensive package that includes social economic and communication factors to address surveillance, SIA gaps and create demand for better delivery of immunization services. Communications indicators should be included in this package. 7. The risk assessment model presented to the conference offered an opportunity for the region to predict polio outbreaks. However, changes in the intensity of polio transmission and data quality seem to affect the accuracy of predictability of the model. Efforts should be made to revise the model and address its limitations. There is also need to initiate consultations before its use. . 8. WHO and partners should promote social, operational and applied research in order to reach the unreached populations and also to address population immunity gaps including adults and migrant / mobile populations 9. WHO and UNICEF should ensure: a) Adequate supply of appropriate types of OPV for use in polio outbreak response in the region. b) Continued and enhanced support for pre-qualification and licensure of additional products to increase vaccine security in the market and at the country-level (2) Reaching Un/Under- Immunized Children in the African Region- Progress, Challenges and Opportunities The Conference noted with satisfaction the progress that had been made in reducing the number of un/under immunized children in the African Region. New innovations had been implemented in some countries such as Ethiopia resulting in significant reduction in the number of unimmunised children in 2010. However, the conference expressed concern on the declining or stagnating performance of routine immunization in a number of countries. In addition, inadequate financing of immunization services in general and routine immunization in particular pose a threat to the maintenance or sustenance of coverage and the introduction of new vaccines. Discrepancies between WHO/UNICEF immunisation coverage estimates and those reported annually by countries were also highlighted. The conference welcomed efforts by countries and immunisation partners in supporting the introduction of new vaccines such as Pneumococcal and Rotavirus vaccines in the region. However there is urgent need to accelerate introduction so that progress towards MDG 4 attainment in the African region could be achieved. 6 The conference proposed the following actions 10. Countries with support from partners should implement all components of RED and other innovative strategies to reduce the number of unimmunized children, especially in the top ten countries with large number of un/under immunized children. 11. Countries should continue working to improve data quality and utilize fora such as EPI managers and regional consultations meetings to identify and address the challenges. 12. The conference welcomed the “Decade of Vaccines” (DoV) and proposed active consultation with the Regional Office and countries in the development and formulations of the delivery component of DoV. 13. Countries with the support of WHO and partners should adopt a holistic approach to synergize immunization with the control of pneumonia and diarrhea within the primary health care context as elaborated in the Alma Ata and Ouagadougou Declarations to accelerate attainment of MDG 4. 14. WHO and partners should support countries to strengthen surveillance capacity for new vaccines for advocacy and support decision making on new vaccines introduction 15. WHO and Partners should support countries to develop local mechanisms to increase funding for immunization services and maintaining immunization as a public health priority. 16. To strengthen logistic and delivery of vaccines, the conference proposed that WHO and partners should consider introducing for discussion a document on the creation of Logisticians for Health during the Regional Committee of Health Ministers (3) Accelerated Disease Control Initiatives in African Region The conference was informed that improvement in the routine measles immunisation coverage was slow, and that only 14 countries in the African Region had maintained at least 80% measles coverage over the past 3 years. In addition, scheduled follow up SIAs could not be implemented on time in some countries due to the failure to mobilise adequate resources from governments and partners. The gaps in routine immunisation coverage and SIAs quality have contributed to the significant increase in the number of measles outbreaks. These outbreaks, due to low population immunity, undermine the progress made and endanger the prospects of meeting the measles pre-elimination targets for 2012. 7 On Maternal and Neonatal Tetanus elimination (MNTE), the conference was informed that a good number of planned SIA activities by countries were not implemented which is affecting the progress towards MNTe. The conference was also informed that the Meningitis Vaccine Project (MVP) between WHO and PATH has resulted in the development of Meningitis A Conjugate Vaccine (MCV) that was pre-qualified in June 2010 and initially rolled out in 3 countries (Burkina Faso, Mali and Niger) but will eventually reach 14 targeted countries. The conference suggested the following actions: 17. In view of resurgence of measles outbreaks in the region, the African Regional Measles TAG should assess the progress towards meeting measles pre-elimination targets and provide guidance to countries 18. The conference noted the efforts by some countries to mobilize resources from within and encouraged all countries to continue mobilizing local resources for measles SIAs 19. In order to support Maternal and Neonatal Tetanus Elimination goals, the conference called upon countries and partner to implement the planned activities to achieve elimination 20. The conference appreciated the recent launch of the Meningitis A Conjugate vaccine in Burkina Faso and calls upon WHO, partners and targeted countries in the meningitis belt to ensure accelerated introduction. 21. The strategy for the control of Viral Hepatitis B in the African region was discussed and the conference requested that this document be disseminated to countries 8 Session 1: Opening Ceremony The Second Annual African Regional Conference on Immunization held in Ouagadougou, Burkina Faso, was officially opened by the Honourable Prime Minister of Burkina Faso, His Excellency Mr. Tertius Zongo. The Conference brought together about 200 participants including the Minister of Health of Burkina Faso, the Minister of Health of Equatorial Guinea who is also Chairman of the WHO Regional Committee, the WHO Director-General, the WHO Regional Director, the President of the Global Health Programme of the Bill and Melinda Gates Foundation and the interim Chief Executive of GAVI. Other participants included parliamentarians from Cameroon and DRC, traditional leaders from Nigeria, National Programme Managers of the Expanded Programme on Immunization, agencies of the United Nations system, partners and the Task Force on Immunization (TFI) which is a regional technical advisory body on immunization set up by the WHO Regional Director in 1989 and experts. The Conference opened with a call for intensification of priority interventions and investments to speed up progress towards achieving the Millennium Development Goals related to maternal and child health. Countries, with the support of WHO and partners, should strive to meet this challenge in order to avoid needless deaths from vaccine preventable diseases (VPDs) such as measles, polio and meningitis, to mention only a few. The Conference made this call through the theme “Reaching Every Child with Immunization”. The five major addresses delivered at the opening ceremony included that of the Prime Minister of Burkina Faso, the WHO Director-General, the WHO Regional Director for Africa, partners and the Chairman of the Conference. The speakers unanimously commended the progress in the control of vaccine-preventable diseases and urged countries to redouble their efforts. In his address, the Prime Minister of Burkina Faso, H.E. Mr Tertius Zongo, expressed optimism about the capacity of African countries to conquer these diseases. He recounted the milestones achieved over the years especially the victory over smallpox, the successful implementation of the Expanded Programme on Immunization and the development of new vaccines. Mr Zongo further invited countries to work out better vaccine procurement procedures, promote vaccine management and give special attention to the side effects of vaccines. For his part, the Chairman of the Conference, Dr Sodiomon Sirima, emphasized the duties and obligations of each and everyone. “We should make all children benefit from the existing preventive facilities”, he said. He warmly congratulated his predecessor, Prof. Peter Ndumbe, on the progress made under his Chairmanship. Addressing the gathering, the WHO Regional Director, Dr Luis Gomes Sambo, hailed the launch of MenAfriVac, the new vaccine against meningococcal meningitis A and underscored the personal commitment of the President of Burkina Faso, H.E. Mr. Blaise Compaore, as sponsor of the initiative to eliminate meningitis epidemics in Africa. He called on countries and partners to make concerted efforts to mobilize additional financial resources in order to guarantee access to this vaccine to rid Africa of the terrible suffering of the past. 9 Dr Sambo informed participants of the progress made in routine immunization with a 79% DPT3 immunization coverage and a spectacular reduction of about 97% of poliomyelitis cases in Nigeria. “The challenge Nigeria now faces is to maintain this achievement” said the WHO Director- General, Dr Margaret Chan who proudly outlined the health benefits of immunization as the best life-saving weapon available. Three-to-five million lives are saved each year through immunization, she added. The Director-General paid tribute to Africa for the Conference theme which, in her opinion, reflects Africa’s vision and commitment in regard to health. Other partners especially GAVI and the Bill and Melinda Gates Foundation added their voices to those of the other speakers in commending the partnership without which no achievement was possible. Bill and Melinda Gates Foundation pledged US$ 10 million for the Decade. GAVI was represented at the Conference by its current acting Chief Executive Officer, Ms Helen Evans, and Bill and Melinda Gates Foundation by Dr Tachi Yamada, President of the Global Health Programme. 10
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