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Handbook of dermatology : a practical manual PDF

419 Pages·2020·3.795 MB·English
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Handbook of Dermatology Handbook of Dermatology A Practical Manual SeconD eDition Margaret W. Mann, MD Associate Professor and Director of Aesthetic Dermatology University Hospitals, Case Western School of Medicine Cleveland, OH, USA Co-Founder Innova Dermatology Hendersonville, TN, USA Daniel L. Popkin, MD PhD Assistant Chief of Dermatology, Louis Stokes VA Medical Center Assistant Professor of Dermatology University Hospitals, Case Western School of Medicine Cleveland, OH, USA Co-Founder Innova Dermatology Hendersonville, TN, USA This edition first published 2020 © 2020 by John Wiley & Sons Ltd Edition History [1e, 2009] All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions. The rights of Margaret W. Mann and Daniel L. Popkin to be identified as the authors of editorial in this work has been asserted in accordance with law. Registered Office(s) John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK Editorial Office 9600 Garsington Road, Oxford, OX4 2DQ, UK For details of our global editorial offices, customer services, and more information about Wiley products visit us at www.wiley.com. Wiley also publishes its books in a variety of electronic formats and by print‐on‐demand. Some content that appears in standard print versions of this book may not be available in other formats. Limit of Liability/Disclaimer of Warranty The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis, or treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages. Library of Congress Cataloging‐in‐Publication Data Names: Mann, Margaret W., author. | Popkin, Daniel L., author. Title: Handbook of dermatology : a practical manual / Margaret W. Mann, Daniel L. Popkin. Description: Second edition. | Hoboken, NJ : Wiley Blackwell, 2020. | Preceded by Handbook of dermatology / Margaret W. Mann ... [et al.]. 2009. | Includes bibliographical references and index. | Identifiers: LCCN 2019003278 (print) | LCCN 2019004180 (ebook) | ISBN 9781118408537 (Adobe PDF) | ISBN 9781118408520 (ePub) | ISBN 9781118408544 (pbk.) Subjects: | MESH: Skin Diseases–diagnosis | Skin Diseases–therapy | Dermatologic Agents–therapeutic use | Handbook Classification: LCC RL74 (ebook) | LCC RL74 (print) | NLM WR 39 | DDC 616.5–dc23 LC record available at https://lccn.loc.gov/2019003278 Cover Design: Wiley Cover Images: © STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY/Getty Images Set in 7.5/9.5 Frutiger by SPi Global, Pondicherry, India 10 9 8 7 6 5 4 3 2 1 Dedication This second edition is dedicated to our son Samuel. Without you, completing this second edition would have been so much faster and less fun. Contents Preface, xv Acknowledgments, xvii Part 1 General Dermatology, 1 Common Work-uPs, signs, And mAnAgement, 3 dermatologic differential Algorithm, 3 direct immunofluorescence (dif), 3 False positive/negative diFs, 3 Workup Quick reference orders, 4 Acne, 6 Alopecia Workup, 7 telogen effluvium, 10 Androgenic alopecia, 10 Alopecia areata, 11 other alopecia treatments, 12 Aphthosis Workup and treatment, 13 dermatologic signs, 15 Folliculitis, 21 melasma, 22 immunology And immunologiC diseAse, 24 lupus erythematosus, 24 Autoantibody, 26 sensitivities and specificities, 26 in connective tissue diseases, 28 Anti‐nuclear antibodies, 29 AnCA (Anti‐neutrophil cytoplasmic antibodies), 30 treatment of AnCA‐associated vasculitis, 30 Vasculitis, 31 small vessel vasculitis, 31 medium vessel vasculitis, 33 large vessel vasculitis, 34 Cryoglobulinemia, 34 Bullous disorders, 36 intracorneal/subcorneal, 36 intraepidermal, 36 suprabasilar, 37 subepidermal with little inflammation, 37 epidermolysis bullosa, 39 major bullous diseases – clinicopathologic findings, 42 vii Complement, 46 Angioedema and complement levels, 46 Complement deficiencies, 47 gVHd, 47 HlA associations, 48 th profiles, 50 sPeCiAl sites: glAnds, nAil, Bone, muCosA, 51 glands, 51 nail terminology, 53 disorders or drugs associated with nail, bone, or ocular findings, 57 genital ulcers, 67 inFeCtion And inFestAtions, 68 Fungal disease / mycoses, 68 laboratory tests, 68 superficial mycoses, 68 Cutaneous mycoses, 69 subcutaneous mycoses, 71 systemic mycoses, 73 opportunistic mycoses, 75 Viruses and diseases, 78 Human papilloma virus, 79 other viral diseases, 80 infections/Bugs, 83 Vector‐borne diseases, 83 Creatures in dermatology, 88 ContACt And PlAnt dermAtitis, 93 Patch testing, 93 Common contact allergens, 95 Allergic vs. irritant contact dermatitis, 104 Allergens – location specific, 105 Features suggestive of specific irritant/toxin, 106 Plants and dermatoses, 106 tumors snd inFiltrAtes, 109 Cutaneous t Cell lyphoma, 109 Cutaneous B‐cell lymphoma, 113 leukemia cutis, 113 monoclonal gammopathies in dermatology, 114 tumors and gene associations, 115 For melanoma, BCC, and sCC, see skin Cancer, 221 viii

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