Gastrointestinal and Liver Pathology: A Volume in the Series: Foundations in Diagnostic Pathology PDF
Preview Gastrointestinal and Liver Pathology: A Volume in the Series: Foundations in Diagnostic Pathology
GASTROINTESTINAL AND LIVER PATHOLOGY GASTROINTESTINAL AND LIVER PATHOLOGY A Volume in the Series FOUNDATIONS IN DIAGNOSTIC PATHOLOGY SECOND EDITION EDITED BY Christine A. Iacobuzio-Donahue, MD, PhD Associate Professor of Pathology, Oncology, and Surgery Johns Hopkins Medical Institutions Department of Pathology Division of Gastrointestinal and Liver Pathology Baltimore, Maryland Elizabeth Montgomery, MD Professor of Pathology, Oncology, and Orthopedic Surgery Johns Hopkins Medical Institutions Department of Pathology Division of Gastrointestinal and Liver Pathology Baltimore, Maryland SERIES EDITOR John R. Goldblum, MD, FCAP, FASCP, FACG Chairman, Department of Anatomic Pathology The Cleveland Clinic Foundation Cleveland Clinic Lerner College of Medicine Case Western Reserve University Cleveland, Ohio 1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103-2899 GASTROINTESTINAL AND LIVER PATHOLOGY, SECOND EDITION ISBN: 978-1-4377-0925-4 (A Volume in the Series Foundations in Diagnostic Pathology Series edited by John R. Goldblum, MD) Copyright 2012, 2005 by Saunders, an imprint of Elsevier Inc. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluat- ing and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. ISBN: 978-1-4377-0925-4 Executive Publisher: William Schmitt Senior Developmental Editor: Andrew Hall Publishing Services Manager: Anne Altepeter Senior Project Manager: Beth Hayes Project Manager: Cindy Thoms Senior Book Designer: Lou Forgione Printed in China Last digit is the print number: 9 8 7 6 5 4 3 2 1 To Tim—my husband, my best friend, my constant supporter, and the most decent person I have ever known —CID To Sasha, Peter Alex, Sean, and Jonathan —EM This page intentionally left blank Contributors Carol Adair, MD H. Parry Dilworth, MD Pathology Residency Program Director Abbott Northwestern Laboratories Baylor University Medical Center Minneapolis, Minnesota Dallas, Texas Epithelial Neoplasms of the Stomach, Neoplasms of Pathology of the Anus the Small Intestine, Gastrointestinal Lymphoma Syed Z. Ali, MD Theresa S. Emory, MD Professor, Departments of Pathology and Radiology Clinical Associate Professor Johns Hopkins University School of Medicine Department of Pathology Attending, Department of Pathology East Tennessee State University Johns Hopkins Hospital Quillen College of Medicine Baltimore, Maryland Johnson City, Tennessee Non-Neoplastic and Neoplastic Pathology of the Highlands Pathology Consultants Pancreas Bristol, Tennessee Idiopathic Inflammatory Bowel Disease Pedram Argani, MD Department of Pathology James R. Eshleman, MD, PhD Johns Hopkins University School of Medicine Department of Pathology Staff Pathologist Department of Oncology Johns Hopkins Hospital Associate Director Baltimore, Maryland Molecular Diagnostics Laboratory Pathology of the Gallbladder and Extrahepatic Bile Johns Hopkins Medical Institutions Ducts Baltimore, Maryland Molecular Diagnostics in Gastrointestinal Pathology David Baewer, MD, PhD Department of Pathology Hubert H. Fenton, MD Johns Hopkins Medical Institutions Mercy Hospital Baltimore, Maryland Baltimore, Maryland Pathology of the Anus Epithelial Neoplasms of the Stomach, Gastrointestinal Lymphoma Baishali Bhattacharya, MD, MPH Surgical and Gastroenterology Pathologist Cyril Fisher, MD, DSc, FRCPath Caris Life Sciences Professor of Tumor Pathology Phoenix, Arizona Department of Histopathology Non-Neoplastic Disorders of the Stomach Consultant Pathologist Institute of Cancer Research Toby C. Cornish, MD, PhD Royal Marsden Hospital Johns Hopkins Hospital London, United Kingdom Department of Surgical Pathology Gastrointestinal Mesenchymal Tumors Baltimore, Maryland Neoplasms of the Small Intestine Baojin Fu, MD Department of Pathology Johns Hopkins Medical Institutions Baltimore, Maryland Non-Neoplastic Disorders of the Esophagus vii viii CONTRIBUTORS Christopher D. Gocke, MD Marc R. Lewin, MD Associate Professor of Pathology and Oncology Propath Dermatology Director of Hematology Molecular Diagnostics Dallas, Texas Johns Hopkins University School of Medicine Epithelial Neoplasms of the Stomach, Baltimore, Maryland Gastrointestinal Lymphoma Gastrointestinal Lymphoma Elizabeth Montgomery, MD Joel K. Greenson, MD Professor of Pathology, Oncology, and Orthopedic Professor, Department of Pathology Surgery University of Michigan Medical School Johns Hopkins Medical Institutions Director, Surgical Pathology Fellowship Program Department of Pathology Department of Pathology Division of Gastrointestinal and Liver Pathology University of Michigan Health System Baltimore, Maryland Ann Arbor, Michigan Tumors of the Esophagus, Non-Neoplastic and Inflammatory/Descriptive/Iatrogenic Colitides Inflammatory Disorders of the Small Bowel, Gastrointestinal Mesenchymal Tumors, Ralph H. Hruban, MD Non-Neoplastic and Neoplastic Disorders of the Professor, Departments of Pathology and Oncology Appendix Johns Hopkins University School of Medicine Pathologist, Department of Pathology Roger Klein Moreira, MD Johns Hopkins Hospital Assistant Professor Baltimore, Maryland Department of Pathology and Cell Biology Non-Neoplastic and Neoplastic Pathology of the Columbia University College of Physicians Pancreas and Surgeons New York, New York Christine A. Iacobuzio-Donahue, MD, PhD Metabolic and Toxic Conditions of the Liver, Associate Professor of Pathology, Oncology, Inflammatory and Infectious Diseases of the Liver, and Surgery Liver Neoplasms Johns Hopkins Medical Institutions Department of Pathology Shiyama Mudali, MD Division of Gastrointestinal and Liver Pathology Department of Pathology Baltimore, Maryland Johns Hopkins Medical Institutions Non-Neoplastic and Inflammatory Disorders of the Baltimore, Maryland Small Bowel, Gastrointestinal Polyposis Syndromes, Gastrointestinal Lymphoma Epithelial Neoplasms of the Colorectum Thong Nguyen, DO Dora M. Lam-Himlin, MD Associate Pathologist Assistant Professor of Laboratory Medicine and Alegent Health System Anatomic Pathology Omaha, Nebraska Mayo Medical School Gastrointestinal Mesenchymal Tumors Senior Associate Consultant in Gastrointestinal Jason Y. Park, MD, PhD, FCAP Pathology Assistant Professor, Department of Pathology Mayo Clinic Arizona University of Texas Southwestern Medical Center Scottsdale, Arizona Associate Director Non-Neoplastic and Neoplastic Disorders of the Advanced Diagnostics Laboratory Appendix Children’s Medical Center Laura W. Lamps, MD Dallas, Texas Associate Professor of Pathology Epithelial Neoplasms of the Stomach Director of Surgical Pathology Department of Pathology University of Arkansas for Medical Sciences Little Rock, Arkansas Infectious Diseases of the Colon CONTRIBUTORS ix M. Eugenia Rueda-Pedraza, MD, Col. USMC Michael Torbenson, MD Clinical Assistant Professor Associate Professor of Pathology Department of Pathology Department of Pathology Uniformed Services University of the Health Sciences Johns Hopkins University School of Medicine Bethesda, Maryland Baltimore, Maryland Chief, Department of Pathology Non-Neoplastic and Neoplastic Disorders of the Heidelberg Military Hospital Appendix Heidelberg, Germany Athanasios C. Tsiatis, MD Non-Neoplastic Disorders of the Esophagus Department of Pathology Chanjuan Shi, MD, PhD Johns Hopkins Medical Institutions Assistant Professor Baltimore, Maryland Vanderbilt University Molecular Diagnostics in Gastrointestinal Pathology Department of Pathology Kay Washington, MD, PhD Nashville, Tennessee Professor, Department of Pathology Non-Neoplastic and Inflammatory Disorders of the Vanderbilt University Medical Center Small Bowel Nashville, Tennessee Leslie H. Sobin, MD Metabolic and Toxic Conditions of the Liver, Department of Hepatic and Gastrointestinal Pathology Inflammatory and Infectious Diseases of the Liver, Armed Forces Institute of Pathology Liver Neoplasms Washington, DC Idiopathic Inflammatory Bowel Disease
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