Frontiers in Peritoneal Dialysis

664 Pages·1986·27.345 MB·English

by  J. W. Dobbie, M. A. Zaki (auth.), John F. Maher M.D., James F. Winchester M.D. (eds.)

FRONTIERS IN
PERITONEAL
DIALYSIS
FRONTIERS IN
PERITONEAL
DIALYSIS
JOHN E MAHER,
EDITED BY M.D.
PROFESSOR OF MEDICINE
UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES
BETHESDA, MARYLAND, U.S.A.
JAMES E WINCHESTER,
M.D.
ASSOCIATE PROFESSOR OF MEDICINE
GEORGETOWN UNIVERSITY MEDICAL CENTER
WASHINGTON, D.C., U.S.A.
Springer-Verlag Berlin Heidelberg GmbH
Officers and Councillors of the International Society for
Peritoneal Dialysis: from left to right, R. Gokal (U.K.),
K. Nolph (U.S.A.), J. Winchester (U.S.A.), A. Trevino
Becerra (Mexico), F. Boen (Netherlands), J. Maher
(U .S.A.), K. Ota (Japan). J. Bergstrom (Sweden): not
shown N. Thomson (Australia).
THIS PUBLICATION IS SUPPORTED IN PART
BY A GRANT FROM THE NATIONAL KIDNEY FOUNDATION, INC.
SUPPORTERS OF THE III INTERNATIONAL SYMPOSIUM ON
PERITONEAL DIALYSIS
Abbott Laboratories Merck. Sharpe and Dohme
American Kidney Fund National Institute of Arthritis, Diabetes and
AMPIDELMED Dialysis Group Digestive and Kidney Diseases
Amuchina National Kidney Foundation of the National Capital
E.I. Dupont De Nemours & Co .. Inc. Area
Fresenius Foundation Pfizer Pharmaceuticals
Fogarty International Center. NIH Stuart Pharmaceuticals Division of ICI Americas,
Gambro Lundia AB Inc.
W.L. Gore and Associates. Inc. Travenol Laboratories
Copyright © 1986. by Springer-Verlag Berlin Heidelberg
Originally published by Springer-Verlag Berlin Heidelberg New York in 1986
All rights reserved. No part of this book may be reproduced in any form, by photostat,
microform. retrieval system, or any other means, without the prior written permission of the publisher.
ISBN 978-3-662-11786-6 ISBN 978-3-662-11784-2 (eBook)
DOI 10.1007/978-3-662-11784-2
Lihrarv of Congress Catalog Card Numher: 85-80\99
Contents
PREFACE
SECTION I: MORPHOLOGY, PHYSIOLOGY, KINETICS, DRUGS
1. THE ULTRASTRUCTURE OF THE PARIETAL PERITONEUM IN NORMAL AND UREMIC
MAN AND IN PATIENTS ON CAPD. J. W Dobbie and M. A. Zaki. 3
2. THE MORPHOLOGY OF THE PERITONEUM IN CAPD PATIENTS. N. Di Paolo, G. Sacchi,
U. Buoncristiani, P Rossi, E. Gaggiotti, C. Alessandrini, L. Ibba, and A. M. Pucci. 11
3. FENESTRATED CAPILLARIES IN THE HUMAN PARIETAL PERITONEUM AND RABBIT
DIAPHRAGMATIC PERITONEUM. L. Gotloib, A. Shustak, P Baf'Sella, and V. Eiali. 20
4. LYMPH FLOW FROM THE PERITONEAL CAVITY IN CAPD PATIENTS. B. Rippe,
G. Stelin, and J. Ahlmen. 24
5. A DISTRIBUTED MODEL OF PERITONEAL TRANSPORT. R. L. Dedrick, M. F Flessner.
J. M. Collins, and J. S. Schultz. 31
6. MAXIMAL PERITONEAL PORE SIZE DETERMINED BY DEXTRAN TRANSPORT.
P Hirszel, J. F Maher. E. Chakrabarti, and R. R. Bennett. 37
7. PERITONEAL ABSORPTION OF MACROMOLECULES. M. F Flessner, R. L. Dedrick,
J. D. Fenstermacher. R. G. Blasberg, and S. M. Sieber. 41
8. PERITONEAL MEMBRANE PERMEABILITY FOR HIGH AND LOW MOLECULAR WEIGHT
PROTEINS (H/LMWP) IN CAPD. W H. Boesken, H. C. Schuppe, A. Seidler. and P Schollmeyer. 47
9. FOLLOW·UP OF PERITONEAL MASS TRANSFER PROPERTIES IN LONG·TERM
CAPD PATIENTS. R. Selgas, A. R. Carmona, M. E. Martinez, J. Conesa, M. FPontan,
E. Huarte, O. Ortega, and L. S·Sicilia. 53
10. DEPENDENCE OF MIDDLE MOLECULAR CLEARANCE ON PROTEIN CONCENTRATION
OF PERITONEAL FLUID. S. R. Ash, Z. T J. Bungu, and F E. Regnier. 56
11. AN INTERNATIONAL SURVEY OF ULTRAFILTRATION IN CAPD. K. D. Nolph. 64
12. CHANGES IN ULTRAFILTRATION AND SOLUTE TRANSPORT DURING CAPD.
L. C. Smeby, T E. Wider¢e, S. Mjdland, and K. Dahl. 68
13. PREDICTION OF CHANGES IN TRANSPERITONEAL WATER TRANSPORT DURING
CAPD - A PROSPECTIVE STUDY. T E. Wider¢e, L. C. Smeby, S. Mjllland, and K. Dahl. 75
14. INFLUENCE OF BLOOD FLOW AND PLASMA PROTEINS ON UF RATE IN PERITONEAL
DIALYSIS. C. Ronco, D. Borin, A. Brendolan, L. Bragantini, S. Chiaramonte, M. Feriani,
A. Fabris, and G. LaGreca. 82
15. PROGNOSTIC VALUE OF PERITONEAL EQUILIBRATION CURVES IN CAPD PATIENTS.
C. Verger. L. Larpent, and M. Dumontet. 88
16. ROLE OF PERITONEAL MEMBRANE HYDRATION IN UF CAPACITY OF PATIENTS
ON CAPD. U. Coli, G. Bazzato, S. Landini, A. Fracasso, F Righetto, F Scan/erta, and P Morachiello. 94
17. STUDIES ON PERITONEAL UF LOSS. THE UF COEFFICIENT (K) AS INDEX
OF THE PM FILTRATION EFFICIENCY. C. Ronco, D. Borin, A. Brendolan,
L. Bragantini, S. Chiaramonte, M. Feriani, A. Fabris, and G. LaGreca. 100
18. INCREASED PERITONEAL UF DUE TO AMPHOTERICIN B-AUGMENTED
SODIUM TRANSPORT. J. F Maher. P Hirszel, E. Chakrabarti, and R. R. Bennett. 106
19. SERUM CONCENTRATION AND PERITONEAL TRANSFER OF ALUMINUM DURING
TREATMENT BY CAPD. J. Rottembourg, 1. L. Gallego, M. C. Jaudon, and 1. P Clavel. 110
20. CALCIUM PERITONEAL MASS TRANSFER IN CAPD. G. Panarello, D. Schinella, P Quaia,
and F Tesio. 117
21. CHANGES IN PLASMA PROTEIN SPECTRA AFTER IP INJECTION OF HYPERTONIC
AND ISOTONIC SOLUTIONS. A. Abramov, A. Khavilov, and V. Fa vorov. 122
22. PHARMACOKINETICS OF CEFOTAXIME DURING CAPD. K. L. Heim,
C. E. Halstenson, C. M. Comty, and G. R. Matzke. 125
23. MULTIPLE DOSE IP VANCOMYCIN KINETICS DURING CAPD. M. C. Rogge, P G. Welling,
C. A. Johnson, and S. W Zimmerman. 131
24. IP ADMINISTRATION OF MOXALACTAM DURING CAPD. G. D. Morse, D. M. Janicke,
R. F. Ca/arell, M. A. Apicella, W J. Jusko, R. C. Venuto, and J. J. Wall-he. 135
v
vi Contents
SECTION II. TECHNOLOGY, ACCESS, SOLUTIONS
25. EXPERIMENTAL AND CLINICAL ORIGINS OF PERITONEAL DIALYSIS FOR
RENAL FAILURE. H. A. Frank. 143
26. THE SORBENT SUSPENSION RECIPROCATING DIALYZER FOR USE IN PERITONEAL
DIALYSIS. S. R. Ash, D. 1. Carr, D. E. Blake, and 1. A. Thornhill. 148
27. APPLICATION OF ANTIBIOTIC BONDING TO CAPD CATHETERS. S. Z. Trooskin,
R. A. Harvey, A. P. Donetz, and R. S. Greco. 157
28. CLINICAL EXPERIENCE IN CAPD USING FLAME-LOCK CONNECTING DEVICE:
A GROUP STUDY. K. Ola. 161
29. INTRALUMINAL THER)VIOSTERILIZATION USING A MICROWAVE AUTOCLAVE.
R. 1. Bielawa, K. L. Carr, and G. G. Bousquet. 166
30. THE ULTRAVIOLET GERMICIDAL SYSTEM: THE ELIMINATION OF DISTAL
CONTAMINATION IN CAPD. R. P. Popovich, 1. W. Moncrief, "P" A. 1. Sorrels-Akar,
C. Mullins-Blackson, and K. Pyle. 169
31. BIOFILM ON TENCKHOFF CATHETERS: A POSSIBLE SOURCE FOR PERITONITIS.
W. P. Reed, ,p' D. Light, and K. A. Newman. 176
32. CAPD: ONE CUFF VS TWO CUFF CATHETERS IN REFERENCE TO INCIDENCE
OF INFECTION. C. Smith. 181
33. PROFOUND REDUCTION IN PERITONITIS IN CAPD USING TRAVENOL
SYSTEM IIR CONNECTORS AND BETADINE. F. M. Parsons, A. M. Brownjohn,
1. H. Turney, G. A. Young, 1. Young, /. H. Ahmed-lushuf, 1. Gibson, and S. Coltman. 183
34. CAPD PERITONITIS AND DIFFERENT CONNECTING DEVICES: A STATISTICAL
COMPARISON. M. Dratwa, F. Collart, and L. Smet. 190
35. CLINICAL APPLICATION OF A MINIATURIZED VARIANT OF THE PERUGIA CAPD
CONNECTION SYSTEM. U. Buoncristiani, C. Carobi, M. Cozzari, and N. Di Paolo. 193
36. PERITONITIS PREVENTION IN CAPD: EFFICACY OF A Y-CONNECTOR AND
DISINFECTANT. A. Cantaluppi, A. Scalamogna, L. Guerra, C. Castelnovo,
G. Graziani, and C. Ponticelli. 198
37. LONG-TERM USE OF UNIDIRECTIONAL BACTERIOLOGIC FILTERS TO REDUCE
PERITONITIS FREQUENCY IN CAPD. C. Rotellar, 1. F. Winchester, S. R. Ash, T. A. Rakowski,
W. F. Barnard, and E. Heeter. 203
38. SKIN REACTION AGAINST THE CATHETER: AN EXPLANATION FOR EXIT SITE
INFECTION IN CAPD. P. Amair, O. de Camejo, O. Dominguez, and M. Boissiere. 207
39. ELIMINATION OF TUNNEL INFECTION. V. L. Poirier. B. D. T. Daly, K. A. Dasse,
C. C. Haudenschild, and R. E. Fine. 210
40. SUCCESSFUL PERITONEAL CATHETER PLACEMENT AFTER MAJOR ABDOMINAL
SURGERY OR PERITONITIS. A. S. Levey, G. M. Simon, 1. McCauley, T. 1. Smith,
S. /. Cho, and J. T. Harrington. 218
41. REDUCTION OF COMPLICATIONS WITH BEDSIDE LATERAL PLACEMENT OF
CATHETER FOR CAPD. 0. Dominguez, P. Amair, R. Fernandez, and M. Boissiere. 223
42. MICROCOMPUTER PERITONEAL PROGRAMMER IN SERVICE OF ACUTE
PERITONEAL DIALYSIS. G. Shilipetar and M. Riggins. 225
43. A COMPARISON OF GLUCOSE POLYMER AND DEXTROSE AS OSMOTIC AGENTS
IN CAPD. J. F. Winchester, L. D. Stegink, S. Ahmad, M. Gross, M. Hammeke, A. M. Horowitz,
1. F. Maher, V. Pollak, T. Rakowski: M. Schreiber, S. Singh, P. Somani, and D. Vidt. 231
44. GLUCOSE POLYMER AS AN OSMOTIC AGENT IN CAPD. C. D. Mistry, R. Gokal,
and N. P. Mallick. 241
45. SUSTAINED UF WITH GELATIN DIALYSIS SOLUTION DURING LONG DWELL DIALYSIS
EXCHANGES IN RATS. Z. J. Twardowski, H. Hain, T. J. McGary, H. L. Moore, and R. S. Keller. 249
46. GLYCEROL INSTEAD OF DEXTROSE AS AN OSMOTIC AGENT IN CAPD.
A. Heaton, D. G. johnston, M. K. Ward, K. G. M. M. Alberti, and D. N. S. Kerr. 255
47. POTENTIALLY IRRITANT GLUCOSE METABOLITES IN UNUSED CAPD FLUID.
/. S. Henderson, /. A. Couper, and A. Lumsden. 261
48. CAPD USING A HIGH CALCIUM CONCENTRATION. 1. 1. Frifelt and F. B. Pedersen. 265
49. IS PERITONEAL ULTRAFILTRATION INFLUENCED BY ACETATE OR LACTATE
BUFFERS? A. Katirtzoglou, G. E. Digenis, P. Kontesis, B. Karamanos, and A. Symvoulidis. 270
Contents vii
50. EVOLUTION OF ULTRAFILTRATION IN CAPD ACCORDING TO THE DIALYSIS
FLUID BUFFER. B. Faller and J. F. Marichal. 274
51. COMPARISON OF DIFFERENT VOLUME MARKERS IN PERITONEAL DIALYSIS.
M. De Paepe. 1. Kips. F. Belpaire. and N. Lameire. 279
52. CRITICAL EVALUATION OF THE INJECTION SITE FOR INSULIN IN CAPD FOR
DIABETIC PATIENTS. J. Rottembollrg. A. Carayon. D. Benoliel. F. Peiliso. and P. Ozamle. 283
SECTION III: CLINICAL EXPERIENCES
53. OVERVIEW OF THE EXPERIENCE OF THE NATIONAL CAPD REGISTRY OF THE
NIH. S. J. ClItlel; S. M. Steinberg. K. D. Nolph. and J. W Novak. 291
54. MULTI-CENTER STUDY ON THE OUTCOME OF PATIENTS ON CAPD AND HEMO-
DIALYSIS. R. Gokal. C. Lloyd. R. Baillod. F. Marsh. C. Ogg. D. Olivel; !vi. Ward. and R. Wilkinson. 293
55. CAPD IN ITALY: A MULTICENTER STUDY. G. Piccoli. G. P. Segoloni. F. Quarello.
and A. Vercellone. 297
56. IS CAPD A SECOND CLASS TREATMENT? S. Shaldon. 304
57. CAPD AND PROTEIN-PERMEATING HEMODIALYSIS: A CLINICAL COMPARISON.
A. Saito. H. Ogawa. T. G. Chung. and K. Maeda. 307
58. CAPD IN THE ELDERLY - REGIONAL EXPERIENCE. A. R. Nissenson. D. E. Gentile.
R. Soderblom. and C. Brax. 312
59. ITALIAN MULTICENTRIC STUDY ON DIABETIC UREMIC PATIENTS TREATED BY CAPD.
G. Triolo. A. Cantaluppi. S. Bellocchi. S. Carozzi. A. Jayme. M. Remondino. and G. P. Segoloni. 318
60. CAPD IN THE DIABETIC: COMPARISON WITH NONDIABETICS ON CAPD.
N. !vi. Thomson. R. W Simpson. R. C. Atkins. and N. Boyce. 323
61. CAPD IN INFANTS. E. C. Kohaut and D. Appell. 329
62. OUTCOME OF HIGH RISK PATIENTS ON CAPD. J. Manos. N. P. Mallick. and R. Gokal. 334
63. FOUR YEAR EXPERIENCE IN CAPD. A. Locatelli. L. De Benedetti. !vi. Fuentes.
E. Chaya. C. Marelli. E. Castiglioni. N. Marchetta. A. Heilbron. L. Lef, and R. Valtuille. 337
64. PROGNOSTIC CORRELATES IN AMBULATORY PERITONEAL DIALYSIS VERSUS
HEMODIALYSIS. R. C. Mackow. W P. Argy. T. A. Rakowski. J. F. Winchester. A. C. Chestel;
A. S. Siemsen. S. Jenkins. and G. E. Schreiner. 341
65. PERITONEAL DIALYSIS FOR IN-HOSPITAL PATIENTS. "P" A. 1. Sorrels-AkaI', !vi. Bobbitt.
F. Agllirre. 1. W Moncrief, and R. P. Popovich. 347
66. RENAL TRANSPLANTATION IN PATIENTS ON CAPO. C. J. Wood. N.!vI. Thomson.
D. F. Scott. S. R. Holdsworth. N. Boyce. and R. C. Atkins. 353
67. HEMODIALYSIS REQUIREMENTS OF CAPD. B. Prowant. 357
68. HOME CAPD NURSE - AN ASSET TO A CAPD PROGRAM. J. Moon. L. Uttley. J. Manos.
N. P. Mallick. and R. Gokal. 360
69. THE TELEPHONE-AN UNDERESTIMATED RESOURCE FOR CAPD NURSING MANAGE-
MENT. W F. Barnard. N. Kloberdanz. W P. Argy. T. A. Rakowski. and J. F. Winchestel: 364
70. PSYCHOLOGICAL AND ECONOMIC ASSESSMENT OF PERITONEAL DIALYSIS
PATIENTS IN NIGERIA. G. Omotosho. 366
71. CAPD ON ALTERNATE DAYS. A. Trevino Becerra and A. Garcia Valencia. 368
72. LOW BUN: A NEGATIVE PROGNOSTIC INDICATOR EARLY IN CAPD. R. C. Mackow.
W P. Argy. T. A. Rakowski. J. F. Winchester. S. Jenkins. 1. l. Shapiro. and G. E. Schreiner. 373
73. TWO YEAR'S EXPERIENCE WITH HIGH VOLUME LOW FREQUENCY CAPD.
Z. J. Twardowski. R. Khanna. L. M. Burrows. L. M. Schmidt. L. P. Ryan. and R. J. Satalowich. 378
74. SUCCESSFUL USE OF CAPD IN REFRACTORY HEART FAILURE. D. Kim. R. Khanna.
G. WII. P. Fountas. M. Druck. and D. Oreopollios. 382
SECTION IV: NUTRITIONAL, METABOLIC, AND PHYSIOLOGICAL EFFECTS
75. NUTRITIONAL REQUIREMENTS WITH CAPD. J. D. Kopple. 389
76. MUSCLE FREE AMINO ACIDS IN PATIENTS TREATED WITH CAPD. B. Lindholm.
A. Alvestrand. and J. Bergstrom. 400
77. TOTAL BODY POTASSIUM AND FAT FREE MASS IN CAPD. T. H. J. Goodship.
B. Clayton. D. Rodham. !vi. K. Ward. and D. N. S. Kerr. 405
viii Contents
78. EFFECT OF INCREASED INSULIN SECRETION DURING CAPD ON POTASSIUM
METABOLISM. A. Oren, R. Bernhard, L. J. Riley, !J:, P. Mojaverian, and R. K. Ferguson. 409
79. AMINO ACID VERSUS GLUCOSE DIALYSIS IN CHILDREN ON CAPD. J. W Balfe,
R. M. Hanning, and S. H. Zlotkin. 416
80. NUTRITIONAL ASPECTS IN CHILDREN ON CAPD. K. E. Bonzel, K. Bonatz, C. Senghaas,
D. E. Muelle,.Wie/el, R. Wartha, N. Gretz, E. Moeller, and O. Mehls. 421
81. INTRAPERITONEAL VERSUS ORAL GLUCOSE LOAD IN CAPD PATIENTS.J. J. Sanchez,
R. Schurig, A. Mahiout, A. Pustelnik, C. Haase, H. Beckel: G. M. Gah/, and M. Kessel. 429
82. THE EFFECT OF CAPD ON LIPID ABNORMALITIES DETECTED BY APOPROTEINS
AND ULTRACENTRIFUGAL LIPID SUBFRACTIONS. K. Ozawa, K. Goto, Y. Ktjima,
/. Nakayama, T. Shoji, T. Sasaoka, T. Akiba, and S. Nakagawa. 432
83. POST·HEPARIN LIPOLYTIC ENZYMES IN PATIENTS ON CAPD. M. K. Chan,
J. W Persaud, Z. Varghese, R. A. Baillod, and J. F. Moorhead. 437
84. BODY COMPOSITION IN UREMIC CHILDREN ON CAPD AND HEMODIALYSIS. N. G. De Santo,
G. Capodicasa, G. Capasso, F. Nuzzi, V. De Simone, F. Scoppa, and C. Giordano. 443
85. PROTEIN AND AMINO ACID LOSSES FROM THE PERITONEUM DURING CAPD AND
CCPD. P. Sandoz, D. Vallance, A. F. Win del: and J. Walls. 446
86. BLOOD PRESSURE ON CAPD: RELATIONSHIP TO SODIUM STATUS, RENIN, AND
ALDOSTERONE, COMPARED WITH HEMODIALYSIS.J. Youmbissi, L. Sellars,
A. C. Shore, T. Poon. and R. Wilkinson. 450
87. INFLUENCE OF HYPERTENSION ON VISION IN DIABETICS UNDERGOING DIALYSIS:
COMPARISON OF PERITONEAL AND HEMODIALYSIS. J. A. Diaz·Buxo, W P. Burgess,
M. Greenman, J. T. Chandlel: C. D. Farmel: and P. J. Walkel: 457
88. BONE HlSTOMORPHOMETRY DURING LONG·TERM CAPD. P. Nilsson, F. Melsen,
N. Gre/berg, B. G. Danielson, and B. Lund. 464
89. EFFECT OF CAPD ON RENAL OSTEODYSTROPHY IN UNMODIFIED PATIENTS MOVING
FROM HEMODIALYSIS TO CAPD. J. A. Pederson, A. 1. Felsen/eld, A. L. Voights, and F. Llach. 471
90. THE TRACE ELEMENTS Br, Co, Cr, Cs, Cu, Fe, Mn, Rb, Se AND Zn IN SERUM, PACKED
CELLS, AND DIALYSATE OF CAPD PATIENTS. B. Wallaeys, R. Cornelis, and N. Lameire. 478
91. HIGH MUSCLE MAGNESIUM AND POTASSIUM IN LONG·TERM REGULAR DIALYSIS
TREATMENT. A. Cantaluppi, S. Casati, G. Graziani, A. Citterio, /. Simoni, L. Borghi,
A. Montanari, and A. Novarini. 482
92. RESPIRATORY FUNCTION IN CAPD. N. Di Paolo, G. Pula, U. Buoncristiani,
P. P. Giomarelli, M. De Mia, B. Biagio/i, E. Zei, F. Manescalchi, and P. Rossi. 486
93. EFFECT ON ERYTHROPOIESIS OF NORMAL MONOCYTES AND PERITONEAL
MACROPHAGES FROM CAPD PATIENTS. S. Lamperi, S. Carozzi, A. Icardi, and G. Reali. 491
94. CREATINE KINASE, AMYLASE, AND PARATHYROID HORMONE IN STABLE CAPD
AND HEMODIALYSIS PATIENTS. J. Rahmat, J. F. McAnally, J. F. Winchestel:
T. A. Rakowski, N. Perri, W P. Argy, and G. E. Schreiner. 499
95. CK ISOENZYMES IN CAPD AND HEMODIALYSIS PATIENTS. E. A. Ross,
D. O. Rodgerson, and A. R. Nissenson. 504
96. TOTAL CK AND CK·MB ELEVATION IN DIALYSIS PATIENTS WITHOUT ACUTE
MYOCARDIAL INFARCTION. Z. Sasson, H. D. Strauss, M. N. Druck, G. Wu, M. Jutkovich,
and D. G. Oreopoulos. 508
97. SEXUAL DYSFUNCTION IN PATIENTS TREATED BY CAPD. R. S. C. Rodger, K. Fletchel:
D. Genner, J. Dewar, M. K. Ward, and D. N. S. Ken: 512
SECTION V: COMPLICATIONS, PERITONITIS, AND RESPONSE TO INFECTION
98. PROGNOSTIC INDICATORS OF HERNIA DEVELOPMENT IN PATIENTS UNDERGOING
CAPD. B. Spinowitz, A. Leggio, M. Galler, R. Golden, J. Rasco/f, and C. Chary tan. 519
99. PERITONEAL CATHETER PERFORATING INTO THE COLON-A SERIOUS
COMPLICATION OF PERITONEAL DIALYSIS. G. Fang. 521
100. CAPD, A PERMANENT STATE OF PERITONITIS: A STUDY ON PEROXIDASE ACTIVITY.
R. H. J. Bellen, J. van der Meulen, H. Verbrugh, E. C. M. Ho/smit, P. L. Oe, and J. Verhoef 524
101. A 3% YEAR EXPERIENCE WITH PERITONITIS IN CHILDREN UNDERGOING CAPD AND
CCPD. H. E. Leichter, /. B. Salusky, M. Wilson, T. Hall, S. C. Jordan, R. B. Ettenger, and R. N. Fine. 531
102. INCIDENCE OF PERITONITIS AND DELAYED·TYPE HYPERSENSITIVITY IN PATIENTS
ON CAPD. D. J. Tsakiris, T. C. Aitchison, J. D. Briggs, B. J. R. Junor. W G. J. Smith, and M. A. Watson. 536
Contents ix
103. THE IMPORTANCE OF IRON FOR BACTERIAL GROWTH IN PERITONEAL DIALYSIS
FLUID. L. L. Bloodworth and M. J. Harbe1: 542
104. THE IMPORTANCE OF INTRACELLULAR ORGANISMS IN CAPD. M. F. Kleiman.
R. 0. Doehring. K. I. Furman. alld G. J. Koomhol 546
105. IMMUNOLOGIC PATTERN IN CAPD PATIENTS WITH LOW OR HIGH PERITONITIS
INCIDENCE. S. Lamperi and S. CaroZZl·. 550
106. DEFECTIVE COMPLEMENT·MEDIATED OPSONIZATION AND LYSIS OF BACTERIA
IN COMMERCIAL PERITONEAL DIALYSIS SOLUTIONS. H. A. Verbl1lgh,
R. P. Verkooyen. J. Verhoef: P. L. Oe. and J. vall der Me/llell. 559
107. OPSONIZING CAPACITY OF PERITONEAL FLUID AND RELATIONSHIP TO
PERITONITIS IN CAPD PATIENTS. S. Steen. P. Brenchley. J. Matzos. R. Pumphrey. alld
R. Gokal. 565
108. OPSONIZATION CAPACITY OF PLASMA AND PERITONEAL DIALYSATE IN CAPD PA·
TIENTS.·F. Giacchillo. M. Rotullno. M. Pozzato. M. Formica. P. Belardi. F. BOllello. and G. Piccoli. 569
109. OPSONICALLY·ACTIVE PROTEINS IN CAPD FLUID. V. M. A. Yewdall.
D. N. Belllletl·Jo·lles. J. S. Cameron. C. S. Ogg. and D. G. Williams. 573
110. DEFECTIVE PERITONEAL POLYMORPHONUCLEAR LEUKOCYTE FUNCTION IN
PATIENTS ON INTERMITTENT PERITONEAL DIALYSIS. EFFECTS OF SOME DIVALENT
IONS AND FIBRONECTIN. E. Cecchin. S. De Marchi. P. De Paoli. G. Salltilli. alld F. Tesio. 579
111. SURFACE MARKED CHARACTERIZATION OF PERITONEAL DIALYSIS PATIENTS'
INTRAPERITONEAL LEUKOCYTES BY MONOCLONAL ANTIBODIES.
B. Challdrasekaran. E. F. Schultz. V. A. De Bari. C. T. ROllquillo. alld M. A. Needle. 583
112. HLA MARKERS AND PERITONITIS IN CAPD PATIENTS. F. Giacchillo. M. Formica.
M. Pozzato. F. Quarello. G. Quattrocchio. M. G. Guerra. F. Peyretti. alld G. Piccoli. 586
113. COMPARISON OF LYMPHOCYTE MARKERS AND LYMPHOBLASTIC
TRANSFORMATION STUDIES OF PATIENTS CONVERTED FROM HEMODIALYSIS TO
CAPD. S. Sillgh. P. Hurtubise. G. Michael. A. Pesce. alld V. Pollak. 591
114. T LYMPHOCYTES SUBSETS IN CAPD AND HEMODIALYSIS (HD) PATIENTS: A
PROSPECTIVE STUDY. F. Collart. C. Tielemalls. R. Wells. L. Schandelle. J. Wydrall.
E. Dupollt. and M. Dratwa. 597
115. IMMUNOGLOBULINS IN CAPD. T. H. J. Goodship. S. M. McLachlall. T. F. H. POOIl.
S. Lloyd. M. K. Ward. and D. N. S. Ken: 600
116. ENHANCED PERITONEAL GENERATION OF VASOACTIVE PROSTAGLANDINS
DURING PERITONITIS IN PATIENTS UNDERGOING CAPD. H. B. Steinhauer. B. GUllte1;
and P. Schollmeyel: 604
117. THROMBOXANE AND PROSTAGLANDIN SYNTHESIS IN HUMAN PERITONEAL
EOSINOPHILS. M. L. Foegh. Y. T. Maddox. J. F. Willchestel; G. E. Schreille1; alld
P. W. Ramwell. 610
118. A COMPARISON OF THE STIMULATORY EFFECTS OF PROSTAGLANDINS ON
HUMAN AND RAT PERITONEAL MACRO PHAGES' c AMP SYNTHESIS.
M. W. J. A. Fierell. M. J. P. Ado(fs. alld I. L. BOllta. 613
119. ALTERATION IN GLUCOSE ABSORPTION DURING PERITONITIS AND ITS EFFECTS
IN DIABETIC AND NONDIABETIC PATIENTS UNDERGOING CAPD. J. Passlick.
A. Frank. M. Berger. and B. Grabellsee. 616
120. SUITABILITY OF POVIDONE·IODINE FORMULATIONS FOR CAPD. K. 1. Furman.
R. O. Doehring. G. T. F. Galasko. M. S. Kleiman. and J. Rudnick. 619
121. NO DIFFERENCE BETWEEN ORAL AND INTRAPERITONEAL TREATMENT OF CAPD
PERITONITIS WITH CEPHRADINE. E. W. Boeschoten. P. 1. Rietra. R. T. Krediet. M. J.
Visser. and L. Arisz. 625
122. HAZARDS OF CAPD: INTERLEUKIN·l PRODUCTION. S. Shaldon. K. M. Koch.
E. Quellhorst. and C. A. Dinarello. 630
123. SCLEROSING ENCAPSULATING PERITONITIS AND OTHER COMPLICATIONS OF
CAPD PERITONITIS. J. Mallos. R. J. Postlethwaite. N. P. Mallick. and R. Gokal. 634
124. SCLEROSING PERITONITIS-A FURTHER COMPLICATION OF CAPD.
D. L. Mc Whillnie. J. A. Bradley. S. P. Bramwell. D. N. H. Hamilton. S. G. Macpherson.
L. P. Cram. /. A. R. More. M. A. FOlwell. W. G. J. Smith. J. D. Briggs. and B. J. R. Junor. 638
125. ~CLEROSING ENCAPSULATING PERITONITIS DURING CAPD. EVALUATION OF THE
POTENTIAL RISK FACTORS. J. Rottembourg. B. Issad. P. Lallglois. F. de Groc. alld M. Legraill. 643
Preface
The III International Symposium on Peritoneal Dial Without the timely contributions of the authors,
ysis was held in Washington, DC, June 17 to 20, these Proceedings would not have been possible.
1984. The 980 attendees came from all continents, Moreover, in their role as organizers of the Sympo
30 countries, and more than half were from the United sium, the Editors appreciate the help of the Executive,
States of America. The diversity of attendance was Scientific, and Local Organizing Committee of the
reflected by a similar dispersion of geography and Symposium.
scientific interests found in the 295 abstracts sub The success of the Symposium also reflects the
mitted for presentation. These Proceedings encom generous support of numerous organizations and
pass 125 manuscripts of papers presented at the foundations listed. Without their assistance the
Symposium as standard slide presentations, posters expenses of the Symposium would have been
or components of panel discussions. overwhelming.
This Symposium was considerably larger than its These Proceedings have been generously sup
two successful predecessors, in Chapala, Mexico, ported by a grant from Abbott Laboratories, by the
1978, and in W. Berlin, FRG, 1981. Indeed, the organi National Kidney Foundation and by contributions
zation of the Symposium has become sufficiently from Gambro AB, Travenol Laboratories, and
formidable that we are pleased that the newly founded The National Institute of Health.
International Society for Peritoneal Dialysis now rep The International Society for Peritoneal Dialysis
resents a resource to facilitate future Symposia. The was established to promote knowledge about peri
President of the new Society is Dr. John F. Maher. toneal dialysis. The Peritoneal Dialysis Bulletin, the
The reader should note that the IV International official publication of the Society, has already pro
Symposium on Peritoneal Dialysis will be held in moted such knowledge commendably. The Editors
Venice, Italy, June 9 to 13, 1987, and also that infor earnestly hope that these Proceedings will foster
mation about joining the Society can be obtained increased knowledge and enlighten and update the
from the Secretary-Treasurer, Dr. J. F. Winchester, reader about the current techniques, results and
Georgetown University Hospital, Washington, DC, problems associated with peritoneal dialysis.
20007, USA.
JOHN F. MAHER. M.D.
JAMES F. WINCHESTER. M.D.
EDITORS
x