Table Of Content

Experimental Gerontology, Vol. 26, pp. IlI-XIII, 1991 0531-5565/91 $3.00 + .00 Printed in the USA. All rights reserved. Copyright © Pergamon Press plc VOLUME 26 Number 1 RicHARD C. ADELMAN and Obituary: Bennett J. Cohen, 1925-1990 Donacp C. GiBson Saran A. Bruce Ultrastructure of dermal fibroblasts during development and aging: Relationship to in vitro senescence of dermal fibroblasts Saran A. Bruce and Longitudinal study of in vivo wound repair and in vitro Scott F. DEAMOND cellular senescence of dermal fibroblasts Yasuko SHINDO, JuNICHI AKIYAMA, Changes in enzyme activities in skin fibroblasts derived Yoriko YAMAZAKI, Kyoue! Saito from persons of various ages and YosHio TAKASE J.P. van Rossum and Oxidation-reduction (redox) potentiometry in blood in D.H.J. SCHAMHART geriatric conditions: A pilot study EvizaBetH A. EDGERTON, Effect of gastric mucosal injury on ornithine decarboxylase Suzanne E.G. FUiGiet, in young and aged rats JEFFREY A. MOsHIER, James S. HATFIELD, Gorpon D. Luk and Apuip P.N. MAJUMDAR Apuip P.N. Masumpar and Gastrin affects enzyme activity and gene expression in the Micuaet A. Dusick aging rat pancreas Donna L. BarrinGER and Autonomic regulation of reflex bradycardia in rats declines Rusen D. BuNaG with age O. Pastoris, L. VeRcEsi and Effects of hypoxia and pharmacological treatment on M. Dossena enzyme activities in skeletal muscle of rats of different ages L. Bonner, D. Dayan, N. Cuimovits Lipid pigment (Lipofuscin) accumulation in rat tongue and I. HAMMEL muscle with aging V.K. Srivastava, R.D. TILLey, Effects of aging and dietary restriction on DNA polymerase S. Miter, R. Hart and expression in mice D. BusBEE 1990 American Federation for Aging Research (AFAR) grant recipients announced Announcement Forthcoming articles Numbers 2/3 Proceedings of a Conference on Correlations of Aging and Space Effects on Biosystems T. FRANKLIN WILLIAMS 121 Foreword: Correlations of aging and space effects on biosystems Eva K. Ray 123 Introduction: Are aging and space effects similar? Frank M. SuLZMAN 131 NASA plans and opportunities RicHarD L. Sprott 135 NIA plans and opportunities Vincent J. CrisTOFALO On understanding the biology of aging: Studies in space RicHARD L. Sprott Cardiovascular Effects James J. SmirH and Posture and the circulation: The age effect Caro J.M. Portu Joun B. CHARLES and Cardiovascular physiology in space flight Micuae. W. Bunco RicuarD L. Sprott Bone Effects Gary M. KieBzak Age-related bone changes ApriAN LeEBLanc and Can the adult skeleton recover lost bone? Victor SCHNEIDER Lex SCHULTHEIS The mechanical control system of bone in weightless spaceflight and in aging RicuarD L. Sprott Sleep Effects Cuar.es A. CZeIsLer, Aucust J. Research on sleep, circadian rhythms and aging: CHIASERA and JEANNE F. DurFy Applications to manned spaceflight Timotuy H. Monk Sleep and circadian rhythms Ricuarp L. Sprott Cellular Effects MILLie HUGHES-FULFORD Altered cell function in microgravity W.C. Hymer and R.E. GrinpeELAND The pituitary: Aging and spaceflown rats RicuarD L. Sprott Immunological Effects Donna M. Murasko, Barsara J. Heterogeneity of changes in lymphoproliferative ability with NeLson, DeBoraH Marovr, I. increasing age MICHAEL GOONEWARDENE and DonaLpD KAYE TAKASHI MAKINODAN, THEODORE J. Cellular immunosenescence: An overview Haun, Skye McDouca.t, Dean T. YamaGucui, MEIKA Fanc and AKIKO [1pA-KLEIN B. Sue Criswe_t-Hupak Immune response during space flight RicHarD L. Sprott Genetics Tuomas E. JoHNson and Caenorhabditis elegans: A model system for space biology Grecory A. NELSON studies Announcements Forthcoming articles Number 4 Karot A. Gutowskli, Jerry L. Flow cytometric analysis of human erythrocytes: I. Probed Hupson and Davip AMINOFF with lectins and immunoglobulins A.ice Rorves-Cur., L. LAZARRE Flow cytometric analysis of human erythrocytes: II. Possible Ocpen, Geneva M. OmaANN and identification of senescent RBC with fluorescently labelled Davip AMINOFF wheat germ agglutinin I. Szapoics, H. ScHuLTuHeIss, H. Age-related decreases in the thyrotropin (TSH) AstieER and F.A. Horster responsiveness to thyrotropin-releasing-hormone (TRH) stimulation and to the inhibitory effect of triiodothyronine (T;); in vitro study on superfused rat pituitaries Lipa Bopner, AHUVA KNYSZYNSKI, The effect of selective desalivation on wound healing in SuHiFRA ADLER-KuNIN and mice Davin DANoN Syune! Kan, S. AsHa Devi and Effect of vitamin E on the accumulation of fluorescent SENCHIRO KAWASHIMA material in cultured cerebral cortical cells of mice BénEpicTE Boyer, Patrick KERN, Age-dependent variations of the biosyntheses of fibronectin ANNIE FourRTANIER and JACQUELINE and fibrous collagens in mouse skin LaBaAT-ROBERT E.A. Sestini, J.C. CarRLson and The effects of ambient temperature on life span, lipid R. ALLsopp peroxidation, superoxide dismutase, and phospholipase A, activity in Drosophila melanogaster M. Hasuimoto, Y. Isuinaca, M. Age-related increase in the uptake of acetylated low density Honpa, M. Oxnoka, S. Morioka and lipoprotein into cultured endothelial cells from rat aorta K. MortyaMa Forthcoming articles Announcements Number 5 DeWrrt G. Hazzarp, Huser R. Meeting report: National Institute on Aging, NIH, workshop Warner and Caces E. Fincu on alternative animal models for research on aging Yoko Tasaki, TAKANE OHARA, Mari Isozyme polymorphisms in human diploid cell strains for Yamamoto and Krvotaka YAMAMOTO research on cellular aging V.K. Srivastava, R.D. Titey, Effect of dietary restriction on the fidelity of DNA R.W. Hart and D. L. Bussee polymerases in aging mice KaTHLEEN A. Hicoins, J.T. Stout, Individual variability in tail tendon fiber break time in three Desra A. HeLcer and Rosert F. age cohorts of different strains of mice PARKER Perer Eppesen, Jan A. ViLLADSEN, Effect of subordinance, lack of social hierarchy, and Henrik D. ViLLapsen and Knup E. restricted feeding on murine survival and virus leukemia HELLER Haroip R. Massie, Mary E. Ascorbic acid in Drosophila and changes during aging Suumway, SANpRA J.P. WuitNey, SyaMaLa M. STEeRNICK and VALERIE R. AIELLO Matt R.J. SHeeney and Bryan E. An alternative explanation for anomalies in ‘‘soluble RoBeRTS lipofuscin’’ fluorescence data from insects, crustaceans, and other aquatic species Letters to the editor Forthcoming articles Announcements Number 6 LEONARD HAYFLICK Editorial K. Yamamoto, K. Kau, H. Konpo, A new human male diploid cell strain, TIG-7: Its age-related M. Matsuo, Y. Suipata, Y. TAsaKk!, changes and comparison with a matched female TIG-1! cell T. Urakxon and H. Ooxa strain S.R.S. RANGAN and Enhanced frequency of spontaneous B cell lines from Patricia ARMATIS Epstein-Barr virus (EBV) seropositive donors 80 years and older H.R. Hirscw and M. Witten The waste-product theory of aging: Simulation of metabolic waste production VOLUME 26 INDEX Marios Kyriazis Applications of chaos theory to the molecular biology of aging IsaBELLE Supey, HILAIRE BaKALA, Age-related changes in the plasma membrane proteoglycans MartTINE PERICHON and of rat kidney glomerular cells JEAN SCHAEVERBEKE WILHELMINA Bopbe and Pyridoxal-5'-phosphate and pyridoxal biokinetics in aging HENK VAN DEN BERG Wistar rats Lasz._o Penzes, JANos Izsak, Effect of aging on cold tolerance and thyroid activity in Dieter KRANZ, KRISTINA SCHUBERT, CBA/Ca inbred mice Raymonp C. Noste and Epit Bereci Harop R. Massie, Uric acid content of Drosophila decreases with aging Mary E. Shumway and Sanpra J.P. WHITNEY Book reviews Forthcoming articles Acknowledgments Announcements Volume 26 Contents, Author and Key Word Index