Eric Wahlberg Jerry Goldstone Emergency Vascular Surgery A Practical Guide Second Edition 123 Emergency Vascular Surgery Eric Wahlberg • Jerry Goldstone Emergency Vascular Surgery A Practical Guide Second Edition Eric Wahlberg Jerry Goldstone Department of Vascular Surgery Division of Vascular Surgery Karolinska Hospital Stanford University School of Medicine Stockholm, Sweden Stanford, CA USA ISBN 978-3-662-54017-6 ISBN 978-3-662-54019-0 (eBook) DOI 10.1007/978-3-662-54019-0 Library of Congress Control Number: 2017954389 © Springer-Verlag GmbH Germany 2007, 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer-Verlag GmbH Germany The registered company address is: Heidelberger Platz 3, 14197 Berlin, Germany Preface As with the first edition, the focus of the second edition of Emergency Vascular Surgery: A Practical Guide remains the management and initial treatment of common emergencies involving the non-cardiac vascular system. As the title implies, it is not meant to be a comprehensive textbook of the management of vascular disease nor is it aimed primarily for the experienced vascular surgery expert. Our purpose is to provide readily available and concise information that will enable surgery trainees and non-vascular surgeons to safely manage patients they may encounter in emergency departments and hospital wards. This is especially important because rapid diagnosis and treatment are manda- tory for the management of the bleeding and ischaemic manifestations of vas- cular disease. It is also important because, as populations in most parts of the world are ageing and vascular diseases become more common, there are an insufficient number of adequately trained vascular specialists to ensure that one will always be immediately available for emergency situations. Like the first, this edition is organised into two main sections: specific anatomic areas and general concepts. All of the chapters have been thor- oughly updated with many new figures and appropriate emphasis on endovas- cular techniques, contemporary diagnostic studies and new pharmacologic agents. Suggested supplemental reading lists at the end of each chapter have been updated. We appreciate and have been gratified by the feedback that we have received from trainees and practitioners who have used the first edition. This is what inspired us to undertake its revision. Hopefully this second edition will continue to serve their needs and contribute to the care of patients everywhere. We gratefully acknowledge the assistance and encouragement of Michael Koy and the production staff at Springer-Verlag. We also acknowledge the inspiration and contributions for the first edition of Par Olofsson, a dear friend and respected colleague. Without Par, neither the first nor the second edition would have been written. Stockholm, Sweden Eric Wahlberg San Francisco, CA, USA Jerry Goldstone 2017 v Contents Part A Specific Areas 1 Vascular Injuries to the Neck . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1.2.1 Causes and Mechanism . . . . . . . . . . . . . . . . . . . . . . . . 4 1.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.3.2 Clinical Signs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.4.1 Penetrating Trauma . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.4.2 Blunt Trauma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 1.5 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 1.5.1 Management Before Treatment . . . . . . . . . . . . . . . . . . 9 1.5.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 1.5.3 Management After Treatment . . . . . . . . . . . . . . . . . . . 13 1.5.4 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 2 Vascular Injuries to the Thoracic Outlet Area . . . . . . . . . . . . . . . 17 2.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 2.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 2.2.1 Magnitude of the Problem . . . . . . . . . . . . . . . . . . . . . . 18 2.2.2 Etiology and Pathophysiology . . . . . . . . . . . . . . . . . . . 19 2.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 2.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 2.3.2 Clinical Signs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 2.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 2.5 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 2.5.1 Management Before Treatment . . . . . . . . . . . . . . . . . . 22 2.5.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 2.5.3 Management After Initial Treatment . . . . . . . . . . . . . . 31 2.6 Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 vii viii Contents 3 Vascular Injuries in the Upper Extremity . . . . . . . . . . . . . . . . . . 35 3.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 3.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 3.2.1 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 3.2.2 Etiology and Pathophysiology . . . . . . . . . . . . . . . . . . . 36 3.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 3.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 3.3.2 Clinical Signs and Symptoms . . . . . . . . . . . . . . . . . . . 37 3.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 3.5 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 3.5.1 Initial Management . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 3.5.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 3.5.3 Management After Treatment . . . . . . . . . . . . . . . . . . . 44 3.6 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 3.7 Latrogenic Vascular Injuries . . . . . . . . . . . . . . . . . . . . . . . . . . 44 3.8 Miscellaneous Vascular Injuries . . . . . . . . . . . . . . . . . . . . . . . 45 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 4 Acute Upper Extremity Ischemia . . . . . . . . . . . . . . . . . . . . . . . . . 47 4.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 4.2 Background and Pathogenesis . . . . . . . . . . . . . . . . . . . . . . . . . 47 4.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 4.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 4.5 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 4.5.1 Initial Management . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 4.5.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 4.5.3 Management After Treatment . . . . . . . . . . . . . . . . . . . 50 4.6 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 5 Abdominal Vascular Injuries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 5.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 5.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 5.2.1 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 5.2.2 Magnitude of the Problem . . . . . . . . . . . . . . . . . . . . . . 54 5.2.3 Etiology and Pathophysiology . . . . . . . . . . . . . . . . . . . 54 5.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 5.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 5.3.2 Clinical Signs and Symptoms . . . . . . . . . . . . . . . . . . . 55 5.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 5.5 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 5.5.1 Management Before Treatment . . . . . . . . . . . . . . . . . . 57 5.5.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 5.5.3 Management After Treatment . . . . . . . . . . . . . . . . . . . 69 5.6 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 5.7 Iatrogenic Vascular Injuries in the Abdomen . . . . . . . . . . . . . . 70 5.7.1 Laparoscopic Injuries . . . . . . . . . . . . . . . . . . . . . . . . . . 70 5.7.2 Iliac Arteries and Veins During Surgery for Malignancies in the Pelvis . . . . . . . . . . . . . . . . . . . 70 Contents ix 5.7.3 Iliac Artery Injuries During Endovascular Procedures . . . . . . . . . . . . . . . . . . . . . . . 71 5.7.4 Iatrogenic Injuries During Orthopedic Procedures . . . 71 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 6 Acute Intestinal Ischemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 6.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 6.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 6.2.1 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 6.2.2 Magnitude of the Problem and Patient Characteristics . . . . . . . . . . . . . . . . . . . . . . 74 6.3 Pathophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74 6.4 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 6.4.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 6.4.2 Physical Examination. . . . . . . . . . . . . . . . . . . . . . . . . . 76 6.5 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 6.5.1 Laboratory Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 6.5.2 Angiography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 6.5.3 Diagnostic Pitfalls . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 6.6 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 6.6.1 Management Before Treatment . . . . . . . . . . . . . . . . . . 78 6.6.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 6.6.3 Management After Treatment . . . . . . . . . . . . . . . . . . . 82 6.7 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 7 Abdominal Aortic Aneurysms . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 7.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 7.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 7.2.1 Magnitude of the Problem . . . . . . . . . . . . . . . . . . . . . . 85 7.2.2 Pathogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 7.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 7.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 7.3.2 Examination . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 7.3.3 Differential Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . 87 7.3.4 Clinical Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 7.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 7.5 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 7.5.1 Management Before Surgery . . . . . . . . . . . . . . . . . . . . 88 7.5.2 Open Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 7.5.3 Management After Treatment . . . . . . . . . . . . . . . . . . . 97 7.6 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98 7.7 Unusual Types of Aortic Aneurysms . . . . . . . . . . . . . . . . . . . . 98 7.7.1 Inflammatory Aneurysm . . . . . . . . . . . . . . . . . . . . . . . 98 7.7.2 Aortocaval Fistula . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98 7.7.3 Thoracoabdominal Aneurysm . . . . . . . . . . . . . . . . . . . 99 7.7.4 Mycotic Aneurysm. . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 7.8 Ethical Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 x Contents 8 Acute Aortic Dissection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 8.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 8.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 8.2.1 Magnitude of the Problem . . . . . . . . . . . . . . . . . . . . . . 104 8.2.2 Etiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 8.2.3 Pathophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 8.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 8.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 8.3.2 Physical Examination. . . . . . . . . . . . . . . . . . . . . . . . . . 109 8.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 8.5 Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 8.5.1 Initial Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 8.5.2 Surgical Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 8.5.3 Type B Dissection . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 8.5.4 Endovascular Treatment . . . . . . . . . . . . . . . . . . . . . . . . 113 8.6 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 9 Vascular Injuries in the Legs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 9.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 9.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 9.2.1 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 9.2.2 Magnitude of the Problem . . . . . . . . . . . . . . . . . . . . . . 116 9.2.3 Etiology and Pathophysiology . . . . . . . . . . . . . . . . . . . 116 9.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117 9.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117 9.3.2 Clinical Signs and Symptoms . . . . . . . . . . . . . . . . . . . 117 9.4 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 9.4.1 Angiography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 9.4.2 CT Angiography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 9.4.3 Duplex Ultrasound . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 9.5 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 9.5.1 Management Before Treatment . . . . . . . . . . . . . . . . . . 119 9.5.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121 9.5.3 Endovascular Treatment . . . . . . . . . . . . . . . . . . . . . . . . 128 9.5.4 Management After Treatment . . . . . . . . . . . . . . . . . . . 128 9.6 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 9.7 Fasciotomy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 9.8 Iatrogenic Vascular Injuries to the Legs . . . . . . . . . . . . . . . . . . 131 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132 10 Acute Leg Ischemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 10.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 10.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 10.2.1 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 10.2.2 Magnitude of the Problem . . . . . . . . . . . . . . . . . . . . . 134 10.2.3 Pathogenesis and Etiology . . . . . . . . . . . . . . . . . . . . . 134 Contents xi 10.3 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135 10.3.1 Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135 10.3.2 Clinical Signs and Symptoms . . . . . . . . . . . . . . . . . . 135 10.3.3 Evaluation of Severity of Ischemia . . . . . . . . . . . . . . 136 10.4 Management and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . 137 10.4.1 Management Before Treatment . . . . . . . . . . . . . . . . . 137 10.4.2 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 10.4.3 Thrombolysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142 10.4.4 Management After Treatment . . . . . . . . . . . . . . . . . . 143 10.5 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 10.6 Conditions Associated with Acute Leg Ischemia . . . . . . . . . 144 10.6.1 Chronic Ischemia of the Lower Extremity . . . . . . . . . 144 10.6.2 Acute Ischemia After Previous Vascular Reconstruction. . . . . . . . . . . . . . . . . . . . . . . 145 10.6.3 Blue Toe Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . 145 10.6.4 Popliteal Aneurysms . . . . . . . . . . . . . . . . . . . . . . . . . 146 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147 Part B General Concepts 11 Acute Complications Following Vascular Interventions . . . . . . 151 11.1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151 11.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152 11.2.1 Magnitude of the Problem . . . . . . . . . . . . . . . . . . . . . 152 11.3 Ischemic Complications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152 11.3.1 Pathophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152 11.3.2 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . 153 11.3.3 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155 11.3.4 Management and Treatment . . . . . . . . . . . . . . . . . . . . 156 11.3.5 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . 157 11.4 Bleeding Complications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158 11.4.1 Causes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158 11.4.2 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . 158 11.4.3 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 11.4.4 Management and Treatment . . . . . . . . . . . . . . . . . . . . 159 11.5 Infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162 11.5.1 Pathophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162 11.5.2 Clinical Presentation . . . . . . . . . . . . . . . . . . . . . . . . . 163 11.5.3 Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 11.5.4 Management and Treatment . . . . . . . . . . . . . . . . . . . . 165 11.5.5 Results and Outcome . . . . . . . . . . . . . . . . . . . . . . . . . 166 11.6 Local Complications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 11.6.1 Lymphocele and Seroma . . . . . . . . . . . . . . . . . . . . . . 167 11.6.2 Postoperative Leg Swelling . . . . . . . . . . . . . . . . . . . . 167 11.6.3 Wound Edge Necrosis . . . . . . . . . . . . . . . . . . . . . . . . 168 11.6.4 Local Nerve Injuries . . . . . . . . . . . . . . . . . . . . . . . . . 168 Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169