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Eighth EDITION Lehninger Principles of `biochemistry PDF

4884 Pages·2020·49.04 MB·english
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Preview Eighth EDITION Lehninger Principles of `biochemistry

1 Lehninger Principles of Biochemistry 2 Lehninger Principles of Biochemistry EIGHTH EDITION David L. Nelson Professor Emeritus of Biochemistry University of Wisconsin–Madison Michael M. Cox Professor of Biochemistry University of Wisconsin–Madison Aaron A. Hoskins Associate Professor of Biochemistry University of Wisconsin–Madison 3 4 Senior Vice President, STEM: Daryl Fox Executive Program Director: Sandra Lindelof Program Manager, Biochemistry: Elizabeth Simmons Senior Marketing Manager: Maureen Rachford Executive Content Development Manager, STEM: Debbie Hardin Development Editor: Catherine Murphy Executive Project Manager, Content, STEM: Katrina Mangold Editorial Project Manager: Karen Misler Director of Content, Life and Earth Sciences: Jennifer Driscoll Hollis Executive Media Editor: Amy Thorne Media Editors: Cassandra Korsvik, Kelsey Hughes Editorial Assistant: Nathan Livingston Marketing Assistant: Morgan Psiuk Director of Content Management Enhancement: Tracey Kuehn Senior Managing Editor: Lisa Kinne Senior Content Project Manager: Vivien Weiss Senior Workflow Project Manager: Paul W. Rohloff Production Supervisor: Robert Cherry Director of Design, Content Management: Diana Blume Design Services Manager: Natasha Wolfe Cover Designer: John Callahan Text Designer: Maureen McCutcheon Art Managers: Janice Donnola, Matthew McAdams Illustrations: Emiko Paul, H. Adam Steinberg Director of Digital Production: Keri deManigold Media Project Manager: Brian Nobile 5 Permissions Manager: Michael McCarty Media Permissions Manager: Christine Buese Photo Researcher: Jennifer Atkins Composition: Lumina Datamatics, Inc. Cover Image, Title Page, and Part Openers: Janet Iwasa, University of Utah Library of Congress Control Number: 2020942138 ISBN-13: 978-1-319-32234-2 (epub) © 2021, 2017, 2013, 2008 by W. H. Freeman and Company All rights reserved. 1    2    3    4    5    6          25    24    23    22    21    20 Macmillan Learning One New York Plaza Suite 4600 New York, NY 10004-1562 www.macmillanlearning.com 6 In 1946, William Freeman founded W. H. Freeman and Company and published Linus Pauling’s General Chemistry, which revolutionized the chemistry curriculum and established the prototype for a Freeman text. W. H. Freeman quickly became a publishing house where leading researchers can make significant contributions to mathematics and science. In 1996, W. H. Freeman joined Macmillan and we have since proudly continued the legacy of providing revolutionary, quality educational tools for teaching and learning in STEM. 7 To Our Teachers Paul R. Burton Albert Finholt Jeff Gelles William P. Jencks Eugene P. Kennedy Homer Knoss Arthur Kornberg I. Robert Lehman Andy LiWang Patti LiWang Melissa J. Moore Douglas A. Nelson Wesley A. Pearson David E. Sheppard JoAnne Stubbe Harold B. White 8 About the Authors David L. Nelson, born in Fairmont, Minnesota, received his BS in chemistry and biology from St. Olaf College in 1964, and earned his PhD in biochemistry at Stanford Medical School, under Arthur Kornberg. He was a postdoctoral fellow at the Harvard Medical School with Eugene P. Kennedy, who was one of Albert Lehninger’s first graduate students. Nelson joined the faculty of the University of Wisconsin–Madison in 1971 and became a full professor of biochemistry in 1982. For eight years he was Director of the Center for Biology Education at the University of Wisconsin–Madison. He became Professor Emeritus in 2013. 9

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