D U A RUG SE AND BUSE A Comprehensive Introduction SEVENTH EDITION Howard Abadinsky St. John’s University Australia•Brazil•Japan•Korea•Mexico•Singapore•Spain•UnitedKingdom•UnitedStates Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. DrugUseandAbuse:AComprehensive ©2011,2008Wadsworth,CengageLearning Introduction,SeventhEdition ALLRIGHTSRESERVED.Nopartofthisworkcoveredbythecopyright HowardAbadinsky hereinmaybereproduced,transmitted,storedorusedinanyformorbyany meansgraphic,electronic,ormechanical,includingbutnotlimitedto Publisher/ExecutiveEditor:LindaSchreiber- photocopying,recording,scanning,digitizing,taping,Webdistribution, Ganster informationnetworks,orinformationstorageandretrievalsystems,except AcquisitionsEditor:CarolynHendersonMeier aspermittedunderSection107or108ofthe1976UnitedStatesCopyright AssistantEditor:ErinAbney Act,withoutthepriorwrittenpermissionofthepublisher. EditorialAssistant:JohnChell Forproductinformationandtechnologyassistance,contactusat MarketingManager:MichelleWilliams CengageLearningCustomer&SalesSupport,1-800-354-9706. MarketingCommunicationsManager: Forpermissiontousematerialfromthistextorproduct, TamiStrang submitallrequestsonlineatcengage.com/permissions. ContentProjectManager:Pre-PressPMG Furtherpermissionsquestionscanbeemailedto [email protected]. CreativeDirector:RobHugel ArtDirector:MariaEpes LibraryofCongressControlNumber:2010922177 PrintBuyer:JudyInouye RightsAcquisitionsAccountManager,Text: ISBN-13:978-0-495-80991-3 RobertaBroyer ISBN-10:0-495-80991-8 RightsAcquisitionsAccountManager,Image: DeanDauphinais Wadsworth ProductionService:Pre-PressPMG 20DavisDrive PhotoResearcher:Pre-PressPMG Belmont,CA94002-3098 USA CoverDesigner:RiezebosHolzbaur/Angelyn Navasca CoverImage:GettyImages©GarryGay CengageLearningisaleadingproviderofcustomizedlearningsolutions withofficelocationsaroundtheglobe,includingSingapore,theUnited Compositor:Pre-PressPMG Kingdom,Australia,Mexico,Brazil,andJapan.Locateyourlocalofficeat www.cengage.com/global. CengageLearningproductsarerepresentedinCanadaby NelsonEducation,Ltd. TolearnmoreaboutWadsworth,visitwww.cengage.com/Wadsworth Purchaseanyofourproductsatyourlocalcollegestoreoratour preferredonlinestorewww.cengagebrain.com. Printed in the United States of America 1 2 3 4 5 6 7 14 13 12 11 10 Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. This book is dedicated to the memory of James A. Inciardi, an outstanding drug researcher and wonderful colleague who will be missed. Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. B C RIEF ONTENTS PREFACE xiv ABOUT THE AUTHOR xix CHAPTER 1 AN INTRODUCTION TO DRUG USE AND ABUSE 1 CHAPTER 2 DRUG USE, DRUG ABUSE, DRUG LEGISLATION: A HISTORY 28 CHAPTER 3 THE BIOLOGY OF PSYCHOACTIVE SUBSTANCES 72 CHAPTER 4 DEPRESSANTS 89 CHAPTER 5 STIMULANTS 122 CHAPTER 6 HALLUCINOGENS, “CLUB DRUGS,” MARIJUANA, INHALANTS, AND PRESCRIPTION DRUGS 153 CHAPTER 7 THE SOCIOLOGY OF DRUG ABUSE 186 CHAPTER 8 THE PSYCHOLOGY OF DRUG USE AND ABUSE 206 CHAPTER 9 DRUG USE AND ABUSE: PREVENTION 224 CHAPTER 10 DRUG USE AND ABUSE: TREATMENT 244 CHAPTER 11 THE BUSINESS OF DRUGS 290 CHAPTER 12 DRUG LAWS AND LAW ENFORCEMENT 334 CHAPTER 13 DRUG USE AND ABUSE POLICY I: THE U.S. MODEL 372 CHAPTER 14 DRUG USE AND ABUSE POLICY II: DECRIMINALIZATION AND HARM REDUCTION 393 GLOSSARY 422 REFERENCES 427 NAME INDEX 465 SUBJECT INDEX 471 iv Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. C ONTENTS PREFACE xiv ABOUT THE AUTHOR xix CHAPTER 1 AN INTRODUCTION TO DRUG USE AND ABUSE 1 Nicotine and Alcohol 2 The Gateway to Illegal Drug Use 2 Drugs: Reaching a Definition 3 Drug Use, Abuse, and Addiction 4 Drug Use Continuum 5 Addiction 6 Definition Determines Response 7 Psychoactive Drugs 7 Depressants 7 Stimulants 7 Hallucinogens, “Club Drugs,” Marijuana/Cannabis, Inhalants, and Prescription Drugs 12 Estimating the Extent of Drug Use 12 National Survey on Drug Use and Health 13 Monitoring the Future 13 Drug Abuse Warning Network 14 NNICC Narcotics Intelligence Estimates 15 Pulse Check 16 Arrestee Drug Abuse Monitoring 16 v Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. vi Contents Drug Use: How Much, How Many? 17 Drugs and Crime 20 Research on Adolescents 21 Research on Adults 22 Drugs Use and Violence 24 Summary 26 Review Questions 27 CHAPTER 2 DRUG USE, DRUG ABUSE, AND DRUG LEGISLATION: A HISTORY 28 Alcohol and the Temperance Movement 29 National Prohibition 31 Opium: A Long History 32 Morphine and Heroin 34 China and the Opium Wars 35 The First Opium War 37 The Second Opium War 37 The Chinese Problem and the American Response 38 The Pure Food and Drug Act 40 China and the International Opium Conference 40 The Harrison Act 42 Case Law Results 44 Narcotic Clinics and Enforcement 45 The Uniform Drug Act 48 Cocaine 50 Cocaine in the Nineteenth Century 51 Cocaine in the Twentieth Century 52 Marijuana 53 Early Marijuana Legislation and Literature 54 Counterculture Use and Changing Laws 55 Amphetamine 57 Barbiturates 58 Tranquilizers and Sedatives 58 Hallucinogens 59 Government Action after World War II 61 A Turn Toward Treatment 62 Comprehensive Drug Abuse Prevention and Control Act of 1970 64 Drug Scare of the 1980s 65 Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Contents vii The Twenty-First Century 66 Summary 67 Review Questions 69 CHAPTER 3 THE BIOLOGY OF DRUG USE AND ABUSE 72 Biological Theories of Drug Use and Abuse 73 Polydrug Use 74 The Disease Model 76 Genetic Predisposition 77 Psychoactive Substances and the Central Nervous System 78 The Brain 79 The Adolescent Brain and Drugs 80 Neurons 80 Neurotransmitters 82 Drug Ingestion 84 Tolerance 85 Drug Cues 86 Summary 87 Review Questions 88 CHAPTER 4 DEPRESSANTS 89 Endorphins 90 Stress and Addiction 91 Heroin 92 Effects of Heroin 96 Tolerance for Heroin 98 Heroin Withdrawal 98 Medical Use of Heroin 99 Dangers of Heroin Use 100 Oxycodone/OxyContin 101 Barbiturates 101 Effects of Barbiturates 102 Tolerance for Barbiturates 103 Barbiturate Withdrawal 103 Medical Use of Barbiturates 103 Dangers of Barbiturate Use 104 Benzodiazepines 104 Effects of Tranquilizers 105 Medical Use of Benzodiazepines 105 Tolerance for Benzodiazepines 106 Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. viii Contents Withdrawal from Benzodiazepines 106 Dangers of Tranquilizer Use 106 Methaqualone 107 Alcohol 107 Effects of Alcohol 110 Alcohol Tolerance and Withdrawal 115 Dangers of Alcohol Use 116 Analogs and Designer Drugs 118 Summary 120 Review Questions 121 CHAPTER 5 STIMULANTS 122 Cocaine 124 Effects of Cocaine 124 Coca Paste and Cocaine Combinations 128 Crack 129 Cocaine Tolerance 131 Cocaine Withdrawal 131 Medical Use of Cocaine 132 Dangers of Cocaine Use 132 Amphetamines 135 Effects of Amphetamines 138 Methamphetamine Tolerance and Withdrawal 140 Medical Use of Amphetamines 140 Dangers of Methamphetamine Use 141 Nicotine 143 Effects of Nicotine 143 Nicotine Tolerance and Withdrawal 146 Dangers of Nicotine Use 147 Herbal Stimulants 149 Caffeine 149 Summary 150 Review Questions 151 CHAPTER 6 HALLUCINOGENS, CLUB DRUGS, MARIJUANA, INHALANTS, AND PRESCRIPTION DRUGS 153 Hallucinogens 154 Lysergic Acid Diethylamide (LSD) 154 Effects of LSD 155 LSD Tolerance and Withdrawal 157 Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Contents ix Dangers of LSD Use 157 Phencyclidine (PCP) 158 Effects of PCP 159 PCP Tolerance and Withdrawal 160 Dangers of PCP Use 160 Mushrooms and Cactus 161 Club Drugs 162 Ecstasy 162 BZP (1-Benzylpiperazine) 167 Paramethoxyamphetamine (PMA) 167 Ketamine 167 Rohypnol 168 GHB and GBL 169 Salvia 170 Marijuana 170 Effects of Cannabis 171 Marijuana Tolerance and Withdrawal 172 Dangers of Marijuana Use 173 Inhalants 174 Effects of Inhalants and Solvents 174 Inhalant Tolerance and Withdrawal 175 Dangers of Inhalant Use 175 Prescription and Over-the-Counter Drug Abuse 175 Nootropics/Neuroenhancers 183 Summary 183 Review Questions 185 CHAPTER 7 THE SOCIOLOGY OF DRUG ABUSE 186 Sociological Theory 187 Stages of Drug Use 188 Alcohol 189 Heroin and Cocaine 190 Anomie 193 Response to Anomie 193 Problems with the Theory 194 The Adaptive Model of Anomie 195 Differential Association 196 Social Control Theory 198 Subcultures and Cultural Deviance 199 Symbolic Interactionism/Labeling 202 Copyright 2010 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part.