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Differential Equation Analysis in Biomedical Science and Engineering : Partial Differential Equation Applications with R PDF

344 Pages·2014·2.217 MB·English
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DIFFERENTIAL EQUATION ANALYSIS IN BIOMEDICAL SCIENCE AND ENGINEERING DIFFERENTIAL EQUATION ANALYSIS IN BIOMEDICAL SCIENCE AND ENGINEERING PARTIAL DIFFERENTIAL EQUATION APPLICATIONS WITH R William E. Schiesser Department of Chemical Engineering Lehigh University Bethlehem, PA CoverDesign:Wiley CoverIllustration:Courtesyoftheauthor Copyright©2014byJohnWiley&Sons,Inc.Allrightsreserved. PublishedbyJohnWiley&Sons,Inc.,Hoboken, NewJersey. PublishedsimultaneouslyinCanada. Nopartofthispublication maybereproduced,storedinaretrievalsystem,ortransmitted inanyformorbyanymeans,electronic, mechanical, photocopying,recording,scanning, orotherwise,exceptaspermittedunderSection107or108ofthe1976UnitedStates CopyrightAct,withouteitherthepriorwrittenpermissionofthePublisher,or authorizationthroughpaymentoftheappropriateper-copyfeetotheCopyrightClearance Center,Inc.,222RosewoodDrive,Danvers,MA01923,(978)750-8400,fax(978) 750-4470,oronthewebatwww.copyright.com. RequeststothePublisherforpermission shouldbeaddressedtothePermissionsDepartment,JohnWiley&Sons,Inc.,111River Street,Hoboken,NJ07030,(201)748-6011,fax(201)748-6008,oronlineat http://www.wiley.com/go/permission. LimitofLiability/DisclaimerofWarranty:Whilethepublisherandauthorhaveusedtheir besteffortsinpreparingthisbook,theymakenorepresentationsorwarrantieswithrespect totheaccuracy orcompletenessofthecontentsofthisbookandspecificallydisclaimany impliedwarrantiesofmerchantability orfitnessforaparticularpurpose.Nowarrantymay becreatedorextendedbysalesrepresentativesorwrittensalesmaterials.Theadviceand strategiescontained hereinmaynotbesuitableforyoursituation.Youshouldconsultwith aprofessionalwhereappropriate.Neitherthepublishernorauthorshallbeliableforany lossofprofitoranyothercommercial damages,includingbutnotlimitedtospecial, incidental, consequential,orotherdamages. Forgeneralinformationonourotherproductsandservicesorfortechnicalsupport,please contactourCustomerCareDepartmentwithintheUnitedStatesat(800)762-2974,outside theUnitedStatesat(317)572-3993orfax(317)572-4002. Wileyalsopublishesitsbooksinavarietyofelectronicformats.Somecontentthat appears inprintmaynotbeavailable inelectronicformats.Formoreinformationabout Wileyproducts,visitourwebsiteatwww.wiley.com. LibraryofCongressCataloging-in-PublicationData: Schiesser,W.E. Differentialequationanalysisinbiomedical scienceandengineering : partial differentialequationapplications withR/WilliamE.Schiesser,DepartmentofChemical Engineering,LehighUniversity,Bethlehem,PA. pagescm Includes bibliographicalreferences andindex. ISBN978-1-118-70518-6(cloth) 1. Biomedicalengineering–Computersimulation. 2. Developmental biology–Simulation methods. 3. Chemotaxis–Dataprocessing. 4. Differentialequations. I.Title. R857.M34.S3452013 610.280285–dc23 2013020441 PrintedintheUnitedStatesofAmerica. 10987654321 To John von Neumann and Alan Turing CONTENTS Preface ix 1. Introduction to Partial Differentiation Equation Analysis: Chemotaxis 1 2. Pattern Formation 43 3. Belousov–Zhabotinskii Reaction System 103 4. Hodgkin–Huxley and Fitzhugh–Nagumo Models 127 5. Anesthesia Spatiotemporal Distribution 163 6. Influenza with Vaccination and Diffusion 207 7. Drug Release Tracking 243 8. Temperature Distributions in Cryosurgery 287 Index 323 vii

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