Diamond Based Materials for Biomedical Applications.

293 Pages·2013·17.108 MB·English

Diamond-based materials for biomedical applications
© Woodhead Publishing Limited, 2013
Related titles:
Surface modifi cation of biomaterials: Methods analysis and applications
(ISBN 978-1-84569-640-5)
Coatings for biomedical applications
(ISBN 978-1-84569-568-2)
Biointegration of medical implant materials: Science and design
(ISBN 978-1-84569-509-5)
Details of these books and a complete list of titles from Woodhead Publishing
can be obtained by:
• visiting our web site at www.woodheadpublishing.com
• contacting Customer Services (e-mail: [email protected]; fax:
[phone]; tel.: [phone] ext. 130; address:
Woodhead Publishing Limited, 80 High Street, Sawston, Cambridge CB22
3HJ, UK)
• contacting our US offi ce (e-mail: [email protected];
tel.: [phone]; address: Woodhead Publishing, 1518 Walnut Street,
Suite 1100, Philadelphia, PA 19102-3406, USA)
If you would like e-versions of our content, please visit our online platform:
www.woodheadpublishingonline.com. Please recommend it to your librarian so
that everyone in your institution can benefi t from the wealth of content on the
site.
We are always happy to receive suggestions for new books from potential
editors. To enquire about contributing to our Biomaterials series, please send
your name, contact address and details of the topic/s you are interested in to
[email protected]. We look forward to hearing from you.
The Woodhead team responsible for publishing this book:
Commissioning Editor: Laura Overend
Publications Coordinator: Adam Davies
Project Editor: Cathryn Freear
Editorial and Production Manager: Mary Campbell
Production Editor: Adam Hooper
Freelance Project Manager: Annette Wiseman
Copyeditor: Eilidh McGregor
Proofreader: Simon Webber
Cover Designer: Terry Callanan
© Woodhead Publishing Limited, 2013
Woodhead Publishing Series in Biomaterials: Number 55
Diamond-based
materials for
biomedical
applications
Edited by

R. Narayan
© Woodhead Publishing Limited, 2013
Published by Woodhead Publishing Limited,
80 High Street, Sawston, Cambridge CB22 3HJ, UK
www.woodheadpublishing.com
www.woodheadpublishingonline.com
Woodhead Publishing, 1518 Walnut Street, Suite 1100, Philadelphia,
PA 19102-3406, USA
Woodhead Publishing India Private Limited, G-2, Vardaan House,
7/28 Ansari Road, Daryaganj, New Delhi – 110002, India
www.woodheadpublishingindia.com
First published 2013, Woodhead Publishing Limited
© Woodhead Publishing Limited, 2013; Chapter 1 © Elsevier, 2011. The publisher has
made every effort to ensure that permission for copyright material has been obtained by
authors wishing to use such material. The authors and the publisher will be glad to hear
from any copyright holder it has not been possible to contact.
The authors have asserted their moral rights.
This book contains information obtained from authentic and highly regarded sources.
Reprinted material is quoted with permission, and sources are indicated. Reasonable efforts
have been made to publish reliable data and information, but the authors and the publishers
cannot assume responsibility for the validity of all materials. Neither the authors nor the
publishers, nor anyone else associated with this publication, shall be liable for any loss,
damage or liability directly or indirectly caused or alleged to be caused by this book.
Neither this book nor any part may be reproduced or transmitted in any form or by any
means, electronic or mechanical, including photocopying, microfi lming and recording, or
by any information storage or retrieval system, without permission in writing from
Woodhead Publishing Limited.
The consent of Woodhead Publishing Limited does not extend to copying for general
distribution, for promotion, for creating new works, or for resale. Specifi c permission
must be obtained in writing from Woodhead Publishing Limited for such copying.
Trademark notice: Product or corporate names may be trademarks or registered
trademarks, and are used only for identifi cation and explanation, without intent to
infringe.
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library.
Library of Congress Control Number: 2012955384
ISBN 978-0-85709-340-0 (print)
ISBN 978-0-85709-351-6 (online)
ISSN 2049-9485 Woodhead Publishing Series in Biomaterials (print)
ISSN 2049-9493 Woodhead Publishing Series in Biomaterials (online)
The publisher’s policy is to use permanent paper from mills that operate a sustainable
forestry policy, and which has been manufactured from pulp which is processed using
acid-free and elemental chlorine-free practices. Furthermore, the publisher ensures that the
text paper and cover board used have met acceptable environmental accreditation standards.
Typeset by Refi neCatch Limited, Bungay, Suffolk
Printed by MPG Printgroup, UK
© Woodhead Publishing Limited, 2013
Contents
Contributor contact details ix
Woodhead Publishing Series in Biomaterials xiii
Part I Introduction to diamond-based materials for
medical applications 1
1 Introduction to medical applications of diamond
particles and surfaces 3
R. J. N ARAYAN and R. D. B OEHM , University of North Carolina
and North Carolina State University, USA and A. V. SU MANT ,
Argonne National Laboratory, USA
1.1 Introduction 3
1.2 Growth of synthetic diamond 4
1.3 Diamond-based medical devices 9
1.4 Functionalization of nanodiamond and nanocrystalline
diamond 13
1.5 Drug delivery using nanodiamond 15
1.6 Imaging with nanodiamond 16
1.7 Conclusion 19
1.8 Acknowledgments 20
1.9 References 20
2 Functionalization of diamond surfaces for medical
applications 25
S. S ZUNERITS and R. BO UKHERROUB , Université Lille 1, France
2.1 Introduction 25
2.2 Electrochemical reduction of aryldiazonium salts 26
2.3 Photochemical modifi cation 29
2.4 Preparation of amine-terminated diamond surfaces 31
2.5 Preparation of oxygen-terminated diamond surfaces 33
2.6 Conclusion and future trends 40
2.7 References 41
© Woodhead Publishing Limited, 2013
vi Contents
3 Biotribology and biological behaviour of
nanocrystalline diamond (NCD) coatings
for medical applications 48
M. A MARAL , University of Aveiro, Portugal
3.1 Introduction to nanocrystalline diamond (NCD) 48
3.2 NCD-coated silicon nitride ceramics as new materials for
joint replacement 50
3.3 Growth and characterization of NCD fi lms deposited on
Si N substrates 51
3 4
3.4 Biotribology of NCD coatings 54
3.5 Biological behaviour of NCD-coated Si N ceramics 61
3 4
3.6 References 67
4 Blood compatibility of diamond-like carbon
(DLC) coatings 71
M. F EDEL , University of Trento, Italy
4.1 Introduction 71
4.2 Diamond-like carbon (DLC) structure, properties and
applications 74
4.3 Deposition techniques for DLC fi lms 77
4.4 DLC blood compatibility 79
4.5 Modifi ed DLC fi lms 87
4.6 Biomedical applications of DLC coatings 91
4.7 Conclusion and future trends 97
4.8 References 97
Part II Biomedical applications of diamond-based
materials 103
5 Nanostructured diamond coatings for orthopaedic
applications 105
S. A. C ATLEDGE, V. T HOMAS and Y. K. V OHRA , University of
Alabama at Birmingham, USA
5.1 Introduction 105
5.2 Ultra-hard carbon coatings 111
5.3 Wear measurements for ceramic-based orthopaedic
implants 121
5.4 Mesenchymal stem cells derived from bone marrow and
their interactions with nanostructured diamond surfaces 125
5.5 Macrophage cell interactions to diamond wear debris 135
5.6 In vivo evaluation of nanostructured diamond surfaces 139
5.7 Future trends 139
5.8 Acknowledgements 141
5.9 References 141
© Woodhead Publishing Limited, 2013
Contents vii
6 Ultrananocrystalline diamond (UNCD) fi lms for
ophthalmological applications 151
O. A UCIELLO and P. G URMAN, Argonne National Laboratory, USA,
A. BE RRA , Universidad Nacional de Buenos Aires, A rgentina ,
M. SA RAVIA , Hospital Austral, Argentina and R. ZY SLER , Centro
Atómico Bariloche, Argentina
6.1 Introduction 151
6.2 The use of ultrananocrystalline diamond (UNCD) fi lms
as coatings in the restoration of sight in people blinded by
degenerated photoreceptors 152
6.3 The use of UNCD fi lms in the treatment of glaucoma 157
6.4 Integrated magnet/superparamagnetic nanoparticles
interacting system for new treatment of retina
detachment 164
6.5 Conclusions 168
6.6 Acknowledgments 169
6.7 References 169
7 Ultrananocrystalline diamond (UNCD) for neural
applications 171
Y-C. C HEN , National Hsinchu University of Education, Taiwan
and Harvard Medical School, USA, D-C. LE E , Institute of Cellular
and System Medicine, Taiwan, N-H. TA I , National Tsing-Hua
University, T aiwan , I-M. CH IU , Institute of Cellular and System
Medicine, Taiwan, National Chung Hsing University, Taiwan and
The Ohio State University, USA
7.1 Introduction 171
7.2 Mechanism aspects of ultrananocrystalline diamond
(UNCD)/neural cell interactions 172
7.3 Methods of guiding neurons 178
7.4 Neural and retinal prostheses 179
7.5 References 183
8 Nanodiamonds for drug delivery systems 186
A. E. M ENGESHA , Drake University, USA and B-B. C. YO UAN ,
University of Missouri-Kansas City, USA
8.1 Introduction 186
8.2 Surface modifi cation of diamond nanoparticles for drug
delivery and targeting 194
8.3 Development of nanodiamond-based drug delivery for
proteins 195
8.4 Development of nanodiamond-based drug delivery for
genes 198
8.5 Development of nanodiamond-based drug delivery for
low molecular weight therapeutic agents 199
© Woodhead Publishing Limited, 2013
viii Contents
8.6 Biocompatibility, biodistribution and biological fate of
nanodiamonds 200
8.7 Conclusions 201
8.8 References 202
9 Diamond nucleation and seeding techniques for
tissue regeneration 206
A. K ROMKA , O. B ABCHENKO , S. P OTOCKY , B. R EZEK ,
A. SV ESHNIKOV and P. D EMO , Academy of Sciences of the Czech
Republic, Czech Republic and T. IZ AK and M. V ARGA , Academy
of Sciences of the Czech Republic, Czech Republic and Slovak
University of Technology in Bratislava, Slovak Republic
9.1 Introduction 206
9.2 Diamond nucleation 208
9.3 Methods for diamond nucleation and seeding 211
9.4 Bias enhanced nucleation in hot fi lament chemical vapour
deposition 214
9.5 Ultrasonic seeding 222
9.6 Seeding using a polymer composite 235
9.7 Spontaneous nucleation 244
9.8 Biological and tissue engineering applications 248
9.9 Acknowledgements 249
9.10 References 249
10 Diamond materials for microfl uidic devices 256
A. K ARCZEMSKA , Lodz University of Technology, Poland
10.1 Introduction 256
10.2 Materials for the manufacture of microfl uidic devices 258
10.3 Diamond microfl uidic devices 261
10.4 Conclusions and future trends 268
10.5 Acknowledgments 269
10.6 References 269
Index 273
© Woodhead Publishing Limited, 2013
Contributor contact details
(* = main contact)
Editor Chapter 2
Roger J. Narayan Sabine Szunerits* and
Joint Department of Biomedical Rabah Boukherroub
Engineering Institut de Recherche
University of North Carolina and Interdisciplinaire (IRI,
North Carolina State University USR 3078)
Raleigh, NC Université Lille1, Parc de la Haute
USA Borne
50 Avenue de Halley – BP 70478
E-mail: [email protected] 59658 Villeneuve d’Ascq
France
Chapter 1
E-mail: [email protected]
Roger J. Narayan* and lille1.fr
Ryan D. Boehm
Joint Department of Biomedical
Chapter 3
Engineering
University of North Carolina and Margarida Amaral
North Carolina State University Department of Material and
Raleigh, NC Ceramics Engineering
USA University of Aveiro
3810-193 Aveiro
E-mail: [email protected] Portugal
E-mail: [email protected]
Anirudha V. Sumant
Center for Nanoscale Materials
Argonne National Laboratory
Argonne, IL
USA
E-mail: [email protected]
ix
© Woodhead Publishing Limited, 2013