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Development of an Agitation Rating Scale for Use with Acute Presentation Behavioral Management Patients Author: Tania Denise Shaffer Strout Persistent link: http://hdl.handle.net/2345/1839 This work is posted on eScholarship@BC, Boston College University Libraries. Boston College Electronic Thesis or Dissertation, 2011 Copyright is held by the author, with all rights reserved, unless otherwise noted. Boston College William F. Connell Graduate School of Nursing DEVELOPMENT OF AN AGITATION RATING SCALE FOR USE WITH ACUTE PRESENTATION BEHAVIORAL MANAGEMENT PATIENTS a dissertation by TANIA D. S. STROUT submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy May, 2011 ©copyright by TANIA D. S. STROUT 2011 Acknowledgements My most sincere thanks to those who have supported the development of my work; I would not have been able to complete this work without their support: • June Andrews Horowitz, Ph.D., R.N., F.A.A.N., Professor, William F. Connell School of Nursing, Boston College, my committee chair, advisor, and guide through this work; • Patricia A. Tabloski, Ph.D., R.N., F.A.A.N., Associate Dean for Graduate Programs and Associate Professor, William F. Connell School of Nursing, Boston College, an agitation expert who makes me think in new ways; • Michael R. Baumann, M.D., Professor, Tufts University School of Medicine and Vice-Chair/Medical Director Maine Medical Center, my research partner and consummate supporter; • Alyce A. Schultz, Ph.D., R.N., F.A.A.N., EBP Concepts, my first research mentor and agitation advisor who instilled in me a love of research; • My wonderful family, without their patience, support, encouragement, and sacrifice, I would not have come this far; and • My incredible classmates: Rachel DiFazio, Douglas Schlichting, Brian French, Martha Healey, and Lisa Wolf – each one of you gave me your unending support, love, and pushes when I needed them. iii Thank you so very much to each of you. I will be forever grateful. Dedication I am honored to dedicate this work to my loving family, who has always supported me in my quest to learn more: • To my wonderful parents, who have selflessly sacrificed to support my education for as long as I can remember. Thank you so much. I would not be in this place without you. • To my beautiful, smart, incredible children: Meighan Li and Molly Xiao Yu. I am sorry that I had to go to school so much. I missed you every minute that I was away but I hope that my example has taught you to work diligently to accomplish your goals. • To my amazingly supportive husband, Ken. Thank you so much for encouraging me to do this, for supporting me, for picking up my slack, and for sticking it out. I love you. I love you all so much and am so grateful to have each of you in my life. Thank you. iv DEVELOPMENT OF AN AGITATION RATING SCALE FOR USE WITH ACUTE PRESENTATION BEHAVIORAL MANAGEMENT PATIENTS Abstract Tania D. S. Strout Advisor: June Andrews Horowitz, Ph.D., R.N., F.A.A.N. Agitation is a distressing set of behaviors frequently observed in emergency department psychiatry patients. Key to developing and evaluating treatment strategies aimed at decreasing and preventing agitation is the availability of a reliable, valid instrument to measure behaviors representative of agitation. Currently, an agitation rating instrument appropriate for use in the emergency setting does not exist and clinicians are left without standard language for communicating about the phenomenon. The Agitation Severity Scale was developed to fill this void using facilitated focus groups to generate an initial item pool. Beginning evidence of content validity was established through a survey of clinical providers and a panel of content experts. The objectives of this methodological study were to: (a) develop an observation-based rating scale to assess the continuum of behaviors known as agitation in adult emergency department patients, and (b) to evaluate the psychometric properties of the newly developed instrument. Psychometric evaluation was conducted using a v sample of 270 emergency department psychiatric patients. A 17-item instrument with a standardized Cronbach’s alpha coefficient of 0.91 resulted, providing evidence of a high degree of internal consistency reliability. Principle components analysis revealed a 4-component solution accounting for 69% of observed variance. Internal consistency reliability ranged from 0.71 to 0.91 for the scale components. Equivalence reliability was established through the evaluation of Agitation Severity Scores assigned by independent evaluators, r = 0.99, Κ = 0.98. Construct validity was established through comparison of mean scores for subjects in the highest and lowest scoring quartiles. A statistically significant difference in scores was noted when comparing these groups, t = -17.688, df = 155, p < 0.001. Convergent validity was evaluated by testing the association between Agitation Severity Scores and scores obtained using a well-established instrument, the Overt Agitation Severity Scale. Pearson’s correlation coefficient for the associations between the scores ranged from 0.91 to 0.93, indicating a strong, positive relationship between the scores. Finally, the Rasch measurement model was employed to further evaluate the functioning of the instrument. In sum, the Agitation Severity Scale was found to be reliable and valid when used to measure agitation in the emergency setting. vi Table of Contents Page Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . iii Dedication . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . iv Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v List of Tables . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi List of Figures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiii CHAPTER 1 1. Overview of the Proposed Study Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Statement of the Problem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Purpose . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Significance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Theoretical Influences . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Research Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Definitions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Assumptions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Limitations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 vii Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 CHAPTER 2 2. Review of the Literature Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Agitation, Anxiety, and Aggression . . . . . . . . . . . . . . . . . . . . . . . . . 19 Research Related to the Measurement of Agitation . . . . . . . . . . . . 24 Agitation Assessment Instruments . . . . . . . . . . . . . . . . . . . . 24 Mania Assessment Instruments . . . . . . . . . . . . . . . . . . . . . . . 36 Psychiatric Symptoms Assessment Instruments . . . . . . . . . 38 Aggression Assessment Instruments . . . . . . . . . . . . . . . . . . 41 Instrument Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Defining the Construct . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Reliability . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Validity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Rasch Models of Measurement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 CHAPTER 3 3. Methodology Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Development of the Scale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 viii Setting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 Sample . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 Study Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 Instruments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 Agitation Severity Scale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 Overt Agitation Severity Scale . . . . . . . . . . . . . . . . . . . . . . . . 67 Analytic Methods. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Protection of Human Subjects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 CHAPTER 4 4. Results Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Data Preparation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Characteristics of the Study Subjects . . . . . . . . . . . . . . . . . . . . . . . . . 76 Research Question 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Research Question 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82 Research Question 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 Research Question 4 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 Research Question 5 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 Summary of Findings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117 ix

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Currently, an agitation rating instrument appropriate for use in the The Brief Agitation Rating Scale (BARS) is a 10-item instrument designed.
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