CURRENT TOPICS IN IONIZING RADIATION RESEARCH Edited by Mitsuru Nenoi Current Topics in Ionizing Radiation Research Edited by Mitsuru Nenoi Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. 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Publishing Process Manager Sandra Bakic Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published March, 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from [email protected] Current Topics in Ionizing Radiation Research, Edited by Mitsuru Nenoi p. cm. ISBN 978-953-51-0196-3 Contents Preface XI Part 1 Molecular Process 1 Chapter 1 Measurement of H2AX Phosphorylation as a Marker of Ionizing Radiation Induced Cell Damage 3 Aida Muslimovic, Pegah Johansson and Ola Hammarsten Chapter 2 Suitability of the -H2AX Assay for Human Radiation Biodosimetry 21 Sandrine Roch-Lefèvre, Marco Valente, Philippe Voisin and Joan-Francesc Barquinero Chapter 3 Biological Dosimetry of Ionizing Radiation 31 Aurélie Vaurijoux, Gaëtan Gruel, Sandrine Roch-Lefèvre and Philippe Voisin Chapter 4 Limited Repair of Critical DNA Damage in Cells Exposed to Low Dose Radiation 51 Azhub Gaziev and Gadzhi Shaikhaev Chapter 5 Genome Integrity and Organization in the Context of Radiobiology 81 Vladan Ondřej Chapter 6 Mealybug as a Model for Studying Responses to High Doses of Ionizing Radiation 101 Kommu Naga Mohan, Jun Ge and Jayarama S. Kadandale Part 2 Biological Process 117 Chapter 7 Radiation-Sensitivity and Transcription Profiles in Various Mutant p53 Cells 119 Kumio Okaichi, Nanaka Izumi, Yuma Takamura, Shoichi Fukui and Takashi Kudo VI Contents Chapter 8 Modulation of Gene Expression After Exposure to Ionizing Radiation 129 Mitsuru Nenoi and Vares Guillaume Chapter 9 The Role of MicroRNAs in the Cellular Response to Ionizing Radiations 149 Nicolas Joly-Tonetti and Jérôme Lamartine Chapter 10 Protein Ubiquitination in IR-Induced DNA Damage Response 175 Nur Yucer, Yi Shi and Yi Wang Chapter 11 X-Ray-Induced Radioresistance Against High-LET Radiations from Accelerated Neon-Ion Beams in Mice 199 Bing Wang, Kaoru Tanaka, Yasuharu Ninomiya, Kouichi Maruyama, Guillaume Varès, Yi Shang, Kiyomi Eguchi-Kasai and Mitsuru Nenoi Chapter 12 Radiation Toxins – Effects of Radiation Toxicity, Molecular Mechanisms of Action, Radiomimetic Properties and Possible Countermeasures for Radiation Injury 215 Dmitri Popov, Jeffrey Jones and Vacheslav Maliev Chapter 13 Dynamical Aspects of Apoptosis 243 Antonio Bensussen and José Díaz Chapter 14 Modelling Radiation Health Effects 269 Noriyuki B. Ouchi Part 3 Health Effects 297 Chapter 15 Ionizing Radiation Carcinogenesis 299 Otto G. Raabe Chapter 16 Molecular Spectroscopy Study of Human Tooth Tissues Affected by High Dose of External Ionizing Radiation (Caused by Nuclear Catastrophe of Chernobyl Plant) 349 L. A. Darchuk, L. V. Zaverbna, A. Worobiec and R. Van Grieken Chapter 17 Ionizing Radiation in Medical Imaging and Efforts in Dose Optimization 363 Varut Vardhanabhuti and Carl A. Roobottom Chapter 18 Ultrasound Image Fusion: A New Strategy to Reduce X-Ray Exposure During Image Guided Pain Therapies 395 Michela Zacchino and Fabrizio Calliada Chapter 19 Ionizing Radiation Profile of the Hydrocarbon Belt of Nigeria 407 Yehuwdah E. Chad-Umoren Contents VII Part 4 Medical Uses 433 Chapter 20 The Effects of Antioxidants on Radiation-Induced Chromosomal Damage in Cancer and Normal Cells Under Radiation Therapy Conditions 435 Maria Konopacka, Jacek Rogoliński and Krzysztof Ślosarek Chapter 21 Melatonin for Protection Against Ionizing Radiation 443 M. A. El-Missiry, A. I. Othman and M. A. Alabdan Chapter 22 Radiosensitization with Hyperthermia and Chemotherapeutic Agents: Effects on Linear-Quadratic Parameters of Radiation Cell Survival Curves 469 Nicolaas A. P. Franken, Suzanne Hovingh, Arlene Oei, Paul Cobussen, Judith W. J. Bergs, Chris van Bree, Hans Rodermond, Lukas Stalpers, Petra Kok, Gerrit W. Barendsen and Johannes Crezee Chapter 23 Phage-Displayed Recombinant Peptides for Non-Invasive Imaging Assessment of Tumor Responsiveness to Ionizing Radiation and Tyrosine Kinase Inhibitors 495 Hailun Wang, Miaojun Han and Zhaozhong Han Chapter 24 Biosafety in the Use of Radiation: Biological Effects Comparison Between Laser Radiation, Intense Pulsed Light and Infrared and Ultraviolet Lamps in an Experimental Model in Chicken Embryos 511 Rodolfo Esteban Avila, Maria Elena Samar, Gustavo Juri, Juan Carlos Ferrero and Hugo Juri Chapter 25 Alternatives to Radiation Investigations in Orthodontics 527 Shazia Naser-Ud-Din Part 5 Detection and Measurement 555 Chapter 26 Nanoscale Methods to Enhance the Detection of Ionizing Radiation 557 Mark D. Hammig Chapter 27 Glass as Radiation Sensor 579 Amany A. El-Kheshen Chapter 28 Formation and Decay of Colour Centres in a Silicate Glasses Exposed to Gamma Radiation: Application to High-Dose Dosimetry 603 K. Farah, A. Mejri, F. Hosni, A. H. Hamzaoui and B. Boizot VIII Contents Chapter 29 Optical Storage Phosphors and Materials for Ionizing Radiation 625 Hans Riesen and Zhiqiang Liu Chapter 30 Ionizing Radiation Induced Radicals 649 Ahmed M. Maghraby Chapter 31 Atmospheric Ionizing Radiation from Galactic and Solar Cosmic Rays 683 Christopher J. Mertens, Brian T. Kress, Michael Wiltberger, W. Kent Tobiska, Barbara Grajewski and Xiaojing Xu Part 6 Effects on Materials 739 Chapter 32 Total Dose and Dose Rate Effects on Some Current Semiconducting Devices 741 Nicolas T. Fourches Chapter 33 Influence of Ionizing Radiation and Hot Carrier Injection on Metal-Oxide-Semiconductor Transistors 761 Momčilo Pejović, Predrag Osmokrović, Milica Pejović and Koviljka Stanković Chapter 34 New Developments in the Field of Radiochemical Ageing of Aromatic Polymers 817 Emmanuel Richaud, Ludmila Audouin, Xavier Colin, Bruno Fayolle and Jacques Verdu