Computer Methods in Biomechanics and Biomedical Engineering

258 Pages·2016·9.88 MB·English

by  Amit Gefen • Daphne Weihs

Lecture Notes in Bioengineering
Amit Gefen
Daphne Weihs E ditors
Computer Methods
in Biomechanics
and Biomedical
Engineering
Proceedings of the 14th International
Symposium CMBBE, Tel Aviv, Israel, 2016
Lecture Notes in Bioengineering
More information about this series at http://www.springer.com/series/11564
Amit Gefen Daphne Weihs
(cid:129)
Editors
Computer Methods
in Biomechanics
and Biomedical Engineering
Proceedings of the 14th International
Symposium CMBBE, Tel Aviv, Israel, 2016
123
Editors
Amit Gefen Daphne Weihs
Department ofBiomedical Engineering Faculty of Biomedical Engineering
TelAviv University Technion -Israel Institute of Technology
TelAviv Haifa
Israel Israel
ISSN 2195-271X ISSN 2195-2728 (electronic)
Lecture Notesin Bioengineering
ISBN978-3-319-59763-8 ISBN978-3-319-59764-5 (eBook)
DOI 10.1007/978-3-319-59764-5
LibraryofCongressControlNumber:2017943207
©SpringerInternationalPublishingAG2018
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Contents
Computational Fluid Dynamics for Intracranial Aneurysm Rupture
Prediction and Post-treatment Hemodynamic Analysis . .... ..... .... 1
George Albert Einstein, Srinivasan Aishwarya, V. Sreeja and S. Nandhini
Biomechanical Evaluation of Pre- and Post-bilateral Sagittal Split
MandibularOsteotomyonThree-DimensionalModelsforObstructive
Sleep Apnea Using Finite Element Analysis .. .... .... .... ..... .... 11
Srinivasan Aishwarya, George Albert Einstein, S. Nandhini
and K.M. Vinod
A Novel Model for the Optimization of Load Carriage Ergonomics........ 25
Amir Hadid, Gal Gozes, Avihai Atoon, Amit Gefen and Yoram Epstein
Breast Biomechanical Modeling for Compression Optimization
in Digital Breast Tomosynthesis.... .... .... .... .... .... ..... .... 29
Anna Mîra, Ann-Katherine Carton, Serge Muller and Yohan Payan
Device-Related Pressure Ulcers from a Biomechanical Perspective. .... 37
Ayelet Haimy, Kara Kopplin and Amit Gefen
Comparison of Anisotropic Models to Simulate the Mechanical
Response of Facial Skin . .... ..... .... .... .... .... .... ..... .... 43
Cormac Flynn, Andrew T. Taberner, Sidney Fels and Poul M.F. Nielsen
Evaluation of a Mechanically Coupled Reaction–Diffusion Model
for Macroscopic Brain Tumor Growth.. .... .... .... .... ..... .... 57
Daniel Abler and Philippe Büchler
UKA Component Fatigue Test Development Using DOE and FEA ........ 65
D. Levine, Y. Son, J. Phillips and J. Bischoff
Effect of Natural Honey Treatment and External Stretching
on Kinematics of Cell Migration During Gap Closure.. .... ..... .... 75
Y. Berkovitch, S. Toume, A. Gefen and Daphne Weihs
v
vi Contents
3D Vessel Extraction in the Rat Brain from Ultrasensitive Doppler
Images... .... .... .... .... ..... .... .... .... .... .... ..... .... 81
E. Cohen, T. Deffieux, C. Demené, L.D. Cohen and M. Tanter
Fluid–Structure Simulation of a Transcatheter Aortic Valve
Implantation: Potential Application to Patient-Specific Cases..... .... 93
W. Wu, D. Pott, C. Chiastra, L. Petrini, G. Pennati, G. Dubini,
U. Steinseifer, S. Sonntag, M. Kuetting and F. Migliavacca
Continuum-Scale Models for the Evolution of Hypertrophic Scars
and Contractions After Burn Injuries... .... .... .... .... ..... .... 99
Fred Vermolen and Daniël Koppenol
Investigation of the State of Stress Generated by High Loads
in the Ovine Lumbar Intervertebral Disc Using a New Anisotropic
Hyperelastic Model. .... .... ..... .... .... .... .... .... ..... .... 107
Gloria Casaroli, Fabio Galbusera and Tomaso Villa
Soft Tissues’ Loadings on Healthy Knee at Different Physiological
Flexions: A Coupled Experimental–Numerical Approach ... ..... .... 115
Boris Dousteyssier, Jérôme Molimard, Chafiaa Hamitouche,
Woo-Suck Han and Eric Stindel
Preclinical Analysis to Assess Aseptic Loosening of Orthopaedic
Implants.. .... .... .... .... ..... .... .... .... .... .... ..... .... 129
Heidi-LynnPloeg,AnthonyG.Au,AmeetK.Aiyangar,NipunYamdagni,
Kristopher K. Biegler, Matthew W. Squire and Richard L. Illgen II
Study of Unloading at Lower Limbs Orthotics: Experiment
and Simulation .... .... .... ..... .... .... .... .... .... ..... .... 145
Il’ya N. Dashevskiy, Sergey E. Nikitin, Mikhail N. Perel’muter
and Pavel S. Shushpannikov
Statistical ShapeModel Based2D–3DReconstruction oftheProximal
Femur—Influence of Radiographic Femoral Orientation on
Reconstruction Accuracy .... ..... .... .... .... .... .... ..... .... 153
J. O’Connor, M. Rutherford, J. Hill, D. Beverland, N. Dunne
and A. Lennon
Comparison of Different Strain-Based Parameters to Identify Human
Left Ventricular Myocardial Infarct During Diastole: A 3D
Finite-Element Study ... .... ..... .... .... .... .... .... ..... .... 161
Gerardo Kenny Rumindo, Jacques Ohayon, Magalie Viallon,
Mathias Stuber, Pierre Croisille and Patrick Clarysse
Adipogenesis of 3T3L1 Cells Subjected to Tensile Deformations
Under Various Glucose Concentrations.. .... .... .... .... ..... .... 171
Maayan Lustig, Lisa Mor-Yossef Moldovan, Amit Gefen
and Dafna Benayahu
Contents vii
Computer Simulation of Electroporation and Drug Transport
Through Membranes ... .... ..... .... .... .... .... .... ..... .... 175
Nenad Filipovic, Igor Saveljic and Irena Tanaskovic
Development of a Computational Model to Aid Prediction
of Neurosurgical Brain Shift . ..... .... .... .... .... .... ..... .... 181
N.J. Bennion, M. Potts, A.D. Marshall, S. Anderson and S.L. Evans
CoronaryPressureDropandArterialDistensibility––TwoDependent
Parameters.... .... .... .... ..... .... .... .... .... .... ..... .... 189
Oren M. Rotman, Uri Zaretsky, Avraham Shitzer and Shmuel Einav
Biomechanical Gait Assessment on a Patient Undergoing Surgical
Correction of Kyphosis from Severe Ankylosing Spondylitis: A Case
Study .... .... .... .... .... ..... .... .... .... .... .... ..... .... 195
R. Haddas and T. Belanger
Walking Sticks and a Walker Comparison during Gait in Adult
Degenerative Scoliosis Patients..... .... .... .... .... .... ..... .... 203
Ram Haddas and Isador Lieberman
Finite Element Analysis of Pre and Post Lumbar Fusion for Adult
Degenerative Scoliosis Patients..... .... .... .... .... .... ..... .... 209
Ram Haddas, Ming Xu, Isador Lieberman and James Yang
A Finite Element Platform for Helmet Efficacy Evaluation
of Non-Penetrating Projectile Impacts... .... .... .... .... ..... .... 219
Rinat Friedman, Ayelet Haimy, Yoram Epstein and Amit Gefen
Tissue Loads Applied by a Novel Medical Device for Closing
Large Wounds. .... .... .... ..... .... .... .... .... .... ..... .... 223
Rona Katzengold, Moris Topaz and Amit Gefen
Biomechanics of Implant Failure After PSO: Influence
of the Hardware Configuration Through a Finite Element
Analysis.. .... .... .... .... ..... .... .... .... .... .... ..... .... 229
Tomaso Villa, Claudia Ottardi, Luigi La Barbera, Andrea Luca
and Fabio Galbusera
Statistical Shape Modelling to Analyse the Talus in Paediatric
Clubfoot.. .... .... .... .... ..... .... .... .... .... .... ..... .... 235
Yixuan Feng, Aaron Bishop, Daniel Farley, Joseph Mitchell,
Kenneth Noonan, Xiaoping Qian and Heidi-Lynn Ploeg
Growth and Remodeling of Tissue Structure and Properties ..... .... 245
Yoram Lanir
viii Contents
Proximity of Metastatic Cells Strengthens the Mechanical Interaction
with Their Environment. .... ..... .... .... .... .... .... ..... .... 253
Yulia Merkher and Daphne Weihs
Patient-Specific Numerical Model of Calcific Aortic Stenosis and Its
TreatmentbyBalloon-ExpandableTranscatheterAorticValve:Effect
of Positioning on the Anchorage ... .... .... .... .... .... ..... .... 259
Gil Marom, Matteo Bianchi, Ram P. Ghosh and Danny Bluestein
Computational Fluid Dynamics
for Intracranial Aneurysm Rupture
Prediction and Post-treatment
Hemodynamic Analysis
George Albert Einstein, Srinivasan Aishwarya, V. Sreeja
and S. Nandhini
Abstract Intracranial aneurysm is a cerebrovascular disorder that weakens the
intimaofthecerebralarteryorveincausingalocaldilationofthebloodvesselafter
which the blood vessel becomes thin and ruptures without warning. The resultant
bleedingintothespacearoundthebrainiscalledsubarachnoidhemorrhage(SAH).
In this context, there is an urgent need for early aneurysm rupture prediction that
couldsavenumeroushumanlives.Computationalfluiddynamics(CFD)hasproved
to be potent enough for the prediction of intracranial aneurysm rupture. The
computationalanalysisalongwiththeexpertiseinnumericalmethodsforthevirtual
prediction of complicated life-threatening medical disorders is essential to be
focused for the betterment of society. In this research, we aimed to predict
therupture ofintracranial aneurysmthroughdifferent morphological parametersof
the aneurysm and changes in hemodynamics obtained from CFD. The various
treatmentoptionsforintracranialaneurysminvolvesendovascularclipping,coiling
andbothcoilingandstenting.Wedemonstratedquantitativelyandqualitativelythe
hemodynamic changes (velocity, pressure, and wall shear stress—WSS) in artery
afterstentimplantationandcoilingintothe3Dreconstructedpatient-specificartery
model, taking into consideration the non-Newtonian characteristics of blood using
finite element approach. We also performed a comparison between scenarios of
aneurysm and normal artery without aneurysm, which showed considerably high
WSS, pressure, and velocity values in the model with aneurysm. The possible
treatment options for the case were also computationally analyzed with the fluid
structureinteraction(FSI)whichshowedstentingandcoilingconsiderablyreduced
the WSS on the aneurysm dome. It was speculated that low WSS at the tip of the
aneurysm and high WSS on the aneurysm dome is responsible for the rupture of
aneurysm.
G.AlbertEinstein(&)(cid:1)S.Aishwarya(cid:1)V.Sreeja(cid:1)S.Nandhini
DepartmentofBiosciences,EinNelTechnologies,Chennai,TamilNadu,India
e-mail:[email protected]
©SpringerInternationalPublishingAG2018 1
A.GefenandD.Weihs(eds.),ComputerMethodsinBiomechanics
andBiomedicalEngineering,LectureNotesinBioengineering,
DOI10.1007/978-3-319-59764-5_1