BLUEPRINTS OBSTETRICS & GYNECOLOGY Sixth Edition BLUEPRINTS OBSTETRICS & GYNECOLOGY Sixth Edition Tamara Callahan, MD, MPP Assistant Professor Department of Obstetrics and Gynecology Division of Gynecologic Specialties Vanderbilt University Medical Center Nashville, Tennessee Aaron B. Caughey, MD, MPP, MPH, PhD Professor and Chair Department of Obstetrics and Gynecology Oregon Health and Science University Portland, Oregon Acquisitions Editor: Susan Rhyner Product Manager: Jennifer Verbiar Marketing Manager: Joy Fisher-Williams Vendor Manager: Bridgett Dougherty Manufacturing Coordinator: Margie Orzech Design Coordinator: Terry Mallon Production Services: S4Carlisle Publishing Services Copyright © 2013 by Lippincott Williams & Wilkins, a Wolters Kluwer business. 351 West Camden Street Two Commerce Square Baltimore, MD 21201 2001 Market Street Philadelphia, PA 19103 Printed in China All rights reserved. This book is protected by copyright. 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Caughey, Aaron B. II. Title. III. Title: Obstetrics & gynecology. IV. Title: Blueprints obstetrics and gynecology. [DNLM: 1. Pregnancy Complications--Examination Questions. 2. Genital Diseases, Female--Examination Questions. WQ 18.2] 618.0076--dc23 2012028782 DISCLAIMER Care has been taken to confirm the accuracy of the information present and to describe generally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the publication. Application of this informa- tion in a particular situation remains the professional responsibility of the practitioner; the clinical treatments described and recommended may not be considered absolute and universal recommendations. 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Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .x Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xi Abbreviations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xii PART I: Obstetrics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1 Pregnancy and Prenatal Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1 2 Early Pregnancy Complications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13 3 Prenatal Screening, Diagnosis, and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25 4 Normal Labor and Delivery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .40 5 Antepartum Hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62 6 Complications of Labor and Delivery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .78 7 Fetal Complications of Pregnancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .94 8 Hypertension and Pregnancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .111 9 Diabetes During Pregnancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .121 10 Infectious Diseases in Pregnancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .131 11 Other Medical Complications of Pregnancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .147 12 Postpartum Care and Complications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .161 PART II: Gynecology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .174 13 Benign Disorders of the Lower Genital Tract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .174 14 Benign Disorders of the Upper Genital Tract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .187 15 Endometriosis and Adenomyosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .204 16 Infections of the Lower Female Reproductive Tract . . . . . . . . . . . . . . . . . . . . . . .215 17 Upper Female Reproductive Tract and Systemic Infections . . . . . . . . . . . . . . .230 18 Pelvic Organ Prolapse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .239 19 Urinary Incontinence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .250 20 Puberty, the Menstrual Cycle, and Menopause . . . . . . . . . . . . . . . . . . . . . . . . . . . .267 21 Amenorrhea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .281 22 Abnormalities of the Menstrual Cycle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .293 23 Hirsutism and Virilism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .306 24 Contraception and Sterilization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .316 v vi • Contents 25 Elective Termination of Pregnancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .337 26 Infertility and Assisted Reproductive Technologies . . . . . . . . . . . . . . . . . . . . . . .346 27 Neoplastic Disease of the Vulva and Vagina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .360 28 Cervical Neoplasia and Cervical Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .369 29 Endometrial Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .383 30 Ovarian and Fallopian Tube Tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .392 31 Gestational Trophoblastic Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .404 32 Benign Breast Disease and Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .416 Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .434 Answers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .450 Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .466 Contributors Jeff Andrews, MD, FRCSC Sharon Engel, MD Associate Professor Resident, Obstetrics and Gynecology Department of Obstetrics and Gynecology Oregon Health & Science University Division of General Obstetrics and Gynecology Portland, Oregon Vanderbilt University School of Medicine Nashville, Tennessee Abby Furukawa, MD Resident, Obstetrics and Gynecology Suzanne Barakat Oregon Health & Science University Medical student Portland, Oregon University of North Carolina Chapel Hill, North Carolina Karen Gold, MD, MSCI Assistant Professor Alison Barlow, WHNP Director of Resident Education Assistant Professor Department of Obstetrics and Gynecology Department of Obstetrics and Gynecology Division of Female Pelvic Medicine and Reconstructive Division of Midwifery and Advanced Practice Nursing Surgery Vanderbilt University School of Medicine University of Oklahoma - Tulsa Nashville, Tennessee Tulsa, Oklahoma Lisa Bayer, MD Meghana Gowda, MD Fellow, Family Planning Clinical Instructor Oregon Health & Science University Department of Obstetrics and Gynecology Portland, Oregon Division of Female Pelvic Medicine and Reconstructive Surgery Daniel H. Biller, MD Vanderbilt University School of Medicine Assistant Professor Nashville, Tennessee Department of Obstetrics and Gynecology Division of Female Pelvic Medicine and Reconstructive William J. Kellett, DO Surgery Assistant Professor Vanderbilt University School of Medicine Department of Obstetrics and Gynecology Nashville, Tennessee Division of General Obstetrics and Gynecology Vanderbilt University School of Medicine Yvonne W. Cheng, MD, PhD Nashville, Tennessee Assistant Professor University of California, San Francisco Tamara Keown, MSN, WHNP-BC San Francisco, California Assistant Professor Department of Obstetrics and Gynecology Howard Curlin, MD Division of Midwifery and Advanced Practice Nursing Department of Obstetrics and Gynecology Vanderbilt University School of Medicine Madigan Army Medical Center Nashville, Tennessee Tacoma, Washington Amy Doss, MD Fellow, Maternal-Fetal Medicine Oregon Health & Science University Portland, Oregon vii viii • Contributors Dineo Khabele, MD, FACOG, FACS Stacey Scheib, MD Assistant Professor Assistant Professor Department of Obstetrics and Gynecology Department of Gynecology and Obstetrics Division of Gynecologic Oncology Division of Minimally Invasive Gynecology Vanderbilt University School of Medicine Johns Hopkins Hospital Nashville, Tennessee Baltimore, Maryland John Lucas, MD Brian L. Shaffer, MD Assistant Professor Director, Fetal Diagnosis & Treatment Center Department of Obstetrics and Gynecology Oregon Health & Science University Division of Reproductive Endocrinology and Infertility Portland, Oregon Vanderbilt University School of Medicine Nashville, Tennessee Jonas Swartz, MD Resident, Obstetrics and Gynecology Lucy Koroma, MSN, WHNP-BC Oregon Health & Science University Department of Obstetrics and Gynecology Portland, Oregon Divisions of Reproductive Endocrinology and Gynecology May Thomassee, MD Vanderbilt University School of Medicine Clinical Instructor Nashville, Tennessee Department of Obstetrics and Gynecology Division of Minimally Invasive Gynecology Erica Marsh, MD Vanderbilt University School of Medicine Assistant Professor Nashville, Tennessee Department of Obstetrics and Gynecology Divisions of Reproductive Endocrinology and Susan H. Tran, MD Infertility and Reproductive Biology Research Assistant Professor, Maternal-Fetal Medicine Feinberg School of Medicine - Northwestern University Oregon Health & Science University Evanston, Illinois Portland, Oregon John Mission, MD Ashlie Tronnes, MD Resident Fellow, Maternal-Fetal Medicine Obstetrics and Gynecology University of Washington Oregon Health and Science University Seattle, Washington Portland, Oregon Gina Westhoff, MD Melinda New, MD Fellow, Gynecologic Oncology Assistant Professor University of California, San Francisco Director of Resident Education Department of Obstetrics and Gynecology Keenan Yanit, MD Division of Gynecology Resident, Obstetrics and Gynecology Vanderbilt University School of Medicine Oregon Health & Science University Nashville, Tennessee Portland, Oregon Brian Nguyen, MD Jessica L. Young, MD Resident, Obstetrics and Gynecology Assistant Professor Oregon Health & Science University Department of Obstetrics and Gynecology Portland, Oregon Division of General Obstetrics and Gynecology Vanderbilt University School of Medicine Rachel Pilliod, MD Nashville, Tennessee Resident, Obstetrics and Gynecology Brigham & Women’s Hospital Amanda Yunker, DO Boston, Massachusetts Assistant Professor Department of Obstetrics and Gynecology Division of Minimally Invasive Gynecology Vanderbilt University School of Medicine Nashville, Tennessee
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