Biomedical Signal Analysis

717 Pages·2015·11.935 MB·English

by  Rangayyan, Rangaraj M.

BIOMEDICAL
SIGNAL ANALYSIS
IEEE Press
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IEEE Press Editorial Board
Tariq Samad, Editor in Chief
George W. Arnold Vladimir Lumelsky Linda Shafer
Dmitry Goldgof Pui-In Mak Zidong Wang
Ekram Hossain Jeffrey Nanzer MengChu Zhou
Mary Lanzerotti Ray Perez George Zobrist
Kenneth Moore, Director of IEEE Book and Information Services (BIS)
BIOMEDICAL
SIGNAL ANALYSIS
Second Edition
RANGARAJ M. RANGAYYAN
IEEE Press Series in Biomedical Engineering
Metin Akay, Series Editor
IEEE Press
Copyright © 2015 by The Institute of Electrical and Electronics Engineers, Inc.
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DEDICATION
Ma´trde´voˆ bhava
Pitrde´voˆ bhava
A´cha´ryade´voˆ bhava
LookuponyourmotherasyourGod
LookuponyourfatherasyourGod
LookuponyourteacherasyourGod
—fromthesacredVedichymnsoftheTaittireeyaUpanishadofIndia.
Thisbookisdedicatedtothefondmemoryof
mymotherSrimatiPadmaSrinivasanRangayyan
andmyfatherSriSrinivasanMandayamRangayyan,
andtoallofmyteachers,
inparticular,ProfessorIvaturiSuryaNarayanaMurthy.

CONTENTS
Preface xvii
Acknowledgments xxii
Preface: FirstEdition xxiii
Acknowledgments: FirstEdition xxviii
AbouttheAuthor xxxi
SymbolsandAbbreviations xxxiii
1 IntroductiontoBiomedicalSignals 1
1.1 TheNatureofBiomedicalSignals 1
1.2 ExamplesofBiomedicalSignals 4
1.2.1 Theactionpotentialofacardiacmyocyte 4
1.2.2 Theactionpotentialofaneuron 11
1.2.3 Theelectroneurogram(ENG) 12
1.2.4 Theelectromyogram(EMG) 14
1.2.5 Theelectrocardiogram(ECG) 21
1.2.6 Theelectroencephalogram(EEG) 34
vii
viii CONTENTS
1.2.7 Event relatedpotentials(ERPs) 40
1.2.8 Theelectrogastrogram(EGG) 41
1.2.9 Thephonocardiogram(PCG) 42
1.2.10 Thecarotidpulse 46
1.2.11 Signalsfromcatheter tipsensors 48
1.2.12 Thespeechsignal 48
1.2.13 Thevibromyogram(VMG) 54
1.2.14 Thevibroarthrogram(VAG) 54
1.2.15 Otoacousticemission(OAE)signals 56
1.2.16 Bioacousticsignals 56
1.3 ObjectivesofBiomedicalSignalAnalysis 57
1.4 DifficultiesinBiomedicalSignalAnalysis 61
1.5 WhyUseCAD? 64
1.6 Remarks 66
1.7 StudyQuestionsandProblems 66
1.8 LaboratoryExercisesandProjects 69
2 Concurrent,Coupled,andCorrelatedProcesses 71
2.1 ProblemStatement 72
2.2 IllustrationoftheProblemwithCaseStudies 72
2.2.1 TheECGandthePCG 72
2.2.2 ThePCGandthecarotidpulse 73
2.2.3 TheECGandtheatrialelectrogram 74
2.2.4 Cardiorespiratoryinteraction 76
2.2.5 TheimportanceofHRV 77
2.2.6 TheEMGandVMG 78
2.2.7 Theknee jointandmusclevibrationsignals 79
2.3 Application: SegmentationofthePCG 80
2.4 Application: DiagnosisandMonitoringofSleepApnea 81
2.4.1 Monitoringofsleepapneabypolysomnography 83
2.4.2 Homemonitoringofsleepapnea 83
2.4.3 Multivariateandmultiorgananalysis 84
2.5 Remarks 89
2.6 StudyQuestionsandProblems 89
2.7 LaboratoryExercisesandProjects 89
3 FilteringforRemovalofArtifacts 91
3.1 ProblemStatement 92