Biological, Physical and Technical Basics of Cell Engineering

491 Pages·2018·14.184 MB·English

by  Gerhard M. Artmann, Aysegül Artmann, Azhar A. Zhubanova, Ilya Digel

Gerhard M. Artmann
Aysegül Artmann
Azhar A. Zhubanova
Editors
Ilya Digel
Biological, Physical
and Technical Basics
of Cell Engineering
Biological, Physical and Technical Basics
of Cell Engineering
ü
Gerhard M. Artmann Ayseg l Artmann
(cid:129)
Azhar A. Zhubanova Ilya Digel
(cid:129)
Editors
Biological, Physical
and Technical Basics
of Cell Engineering
123
Editors
Gerhard M.Artmann Azhar A.Zhubanova
Institute for Neurophysiology Department ofBiology andBiotechnology,
University of Cologne KazakhstanNationalAcademyofNatural
Cologne Sciences
Germany Al-Farabi Kazakh National University
Almaty
Aysegül Artmann Kazakhstan
Institute for Bioengineering,
MedicalandMolecular Biology Ilya Digel
University of AppliedSciences, Aachen Institute for Bioengineering,
CampusJülich Cell- andMicrobiology
Germany University of AppliedSciences, Aachen
CampusJülich
Germany
ISBN978-981-10-7903-0 ISBN978-981-10-7904-7 (eBook)
https://doi.org/10.1007/978-981-10-7904-7
LibraryofCongressControlNumber:2017964446
©SpringerNatureSingaporePteLtd.2018
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Germany. Cardiomyocytes derived from murine iPS cell line. Red indicates the muscle protein
alpha-actininandbluethecellnuclei.
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Foreword
While writing the preface for Dr. Artmann’s book “Biological, Physical and
Technical Basics of Cell Engineering” published by Springer Nature, a Confucius
quote on learning and friendship came to my mind: “Isn’t it a great pleasure to
studyandpracticewhatyouhavelearned?Isn’titagreatdelightwhenfriendsvisit
from afar?” I have the privilege of knowing Dr. Artmann and many of the authors
of the chapters. In reading this book, I have the great pleasure of renewing my
acquaintancewiththemandreviewingandlearningthecurrentstatesofbiomedical
sciences and bioengineering. This book was written by outstanding scientists and
engineers focusing on the latest developments of bioengineering concepts and
technologies in cell and tissue research. The chapters cover advanced frontier
technologies and address scientific questions in biology and physics that need
analysis and solution in terms of engineering. They provide the readers, including
students,facultyandotherscientistsworkinginacademiaandindustry,withcurrent
information on bioengineering in cell and tissue research. The book aims at pro-
moting readers’ understanding of biosciences, physics, engineering and innovative
technology and their application to advance human health and well-being. This
inspiring book can enhance not only our professional life, but also our under-
standing of what life really is.
University of California, Shu Chien, M.D., Ph.D.
San Diego, CA, USA University Professor of Bioengineering
and Medicine
v
Contents
Part I Biology
Can We Rebuild the Cell Membrane? . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Samar Damiati
Encapsulation of Stem Cells in Research and Therapy . . . . . . . . . . . . . 29
IsgardS.Hueck,JaneFrimodig,PamelaItkin-AnsariandDavidA.Gough
Stem Cells: Cellular and Extracellular Requirements
for Generation and Use . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
Gerd Bungartz and Kathryn Bungartz
A Collagen-Hyaluronic Acid Matrix for Stem Cell Culture . . . . . . . . . . 89
Euisung Chung, Geajin Yoon and Hwal (Matthew) Suh
Rheological Properties of Biological Structures, Scaffolds and Their
Biomedical Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119
Sabra Rostami and Bora Garipcan
Histeresis Loops and Yield Stress in Cell Research . . . . . . . . . . . . . . . . 141
Yong-de Shi
Part II Technology
Functional Toxicology and Pharmacology Test of Cell Induced
Mechanical Tensile Stress in 2D and 3D Tissue Cultures. . . . . . . . . . . . 157
Gerhard M. Artmann, Jürgen Hescheler, Haritha Meruvu, Sefa Kizildag
and Aysegül Artmann
Development in Cell Manipulation Techniques for the Study
of Single Cardiomyocyte Mechanics. . . . . . . . . . . . . . . . . . . . . . . . . . . . 193
Gentaro Iribe
vii
viii Contents
Growth Modelling Promoting Mechanical Stimulation
of Smooth Muscle Cells of Porcine Tubular Organs in
a Fibrin-PVDF Scaffold . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209
Minh Tuấn Dương, Volker Seifarth, Ayşegül Temiz Artmann,
Gerhard M. Artmann and Manfred Staat
Towards Patient-Specific Computational Modeling of hiPS-Derived
Cardiomyocyte Function and Drug Action. . . . . . . . . . . . . . . . . . . . . . . 233
Ralf Frotscher and Manfred Staat
Mechanics of Soft Tissue Reactions to Textile Mesh Implants . . . . . . . . 251
Aroj Bhattarai and Manfred Staat
ExtractionofFusicoccin-likeCompoundsUsingNanocarbonSorbents
and Study of Their Biological and Cytotoxic Activity . . . . . . . . . . . . . . 277
Z. A. Mansurov, S. Azat and A. R. Kerimkulova
Part III Physics
The Fourth Phase of Water: Implications for Energy, Life,
and Health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309
Gerald H. Pollack
Emergence of Organisms from Ordered Mesoscopic States of Water
(Liquids)—Physical Instead of Chemical Origin of Life. . . . . . . . . . . . . 321
Igor Jerman
Magnetic Resonance in Studying Cells, Biotechnology Dispersions,
Fibers and Collagen Based Tissues for Biomedical Engineering. . . . . . . 339
Victor V. Rodin
Novel MRI Contrast from Magnetotactic Bacteria
to Evaluate In Vivo Stem Cell Engraftment. . . . . . . . . . . . . . . . . . . . . . 365
Ji-Hye Jung, Yuko Tada and Phillip C. Yang
Conformational Motions of Disordered Proteins . . . . . . . . . . . . . . . . . . 381
Andreas M. Stadler
Probing the Structure and Dynamics of Cells, Cell Components
and Endogenous Nanoparticles Under Extreme Conditions
with Neutrons. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401
Judith Peters, Ruth Prassl and Philippe Oger
Contents ix
Microbial Sampling from Dry Surfaces: Current Challenges
and Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421
Ilya Digel, Nuraly Sh. Akimbekov, Aida Kistaubayeva
and Azhar A. Zhubanova
The Search for Signatures of Life and Habitability on Planets
and Moons of Our Solar System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457
Oliver Funke and Gerda Horneck
Editors and Contributors
About the Editors
Prof. Gerhard M. Artmann (Germany), Book
Co-editor, Dr. rer. nat. habil. He received his diploma
in physics from the University of Dresden (1974,
GDR), his doctorate in physics from the RWTH
Aachen (1988, West Germany), and his habilitation
from the Technical University of Ilmenau (1998,
Germany). In his opinion, modern Western democracy
and the freedom of the individual must be absolutely
defended including in science. From 1989 to February
2017, he worked at the University of Applied Sciences
Aachen, Germany, as Professor of Biophysics and
Bioengineering. His research has focused on funda-
mentalbiophysicalresearchaswellasthedevelopment
ofadvancedhumancellmeasurementtechniques.Heis
currently working with Prof. Jürgen Hescheler as
Visiting Professor at the University of Cologne in the
Institute of Neurophysiology and is researching stem
cells with him. E-mail: [email protected]
xi
xii EditorsandContributors
Mrs. Prof. Aysegül Artmann (Germany), Book
Co-editor, M.D., Ph.D. She has been a Full Professor
at the University of Applied Sciences Aachen from
2001totoday.Hercareerisunusual.Sheattendedhigh
school, the TED Ankara College (English speaking),
until 1984 and then studied medicine at Ankara
University. She earned her medical doctor degree in
1990.Subsequently,sheworkedinthepharmacological
industry.Later,sheworkedasapracticingphysicianin
various polyclinics, including emergency services.
However, she has always had great interest in medical
research. She earned her medical certificate in physi-
ology. Duringherstay atAkdeniz University, Antalya,
and at Dokuz Eylül University (DEÜTF), she gained
medical laboratory experience. Later on, she not only
worked at the Physiology-Biophysics Department at
DEÜTF as an assistant professor and specialized
academician but also participated in a four-year
biochemistry Ph.D. program. Her Ph.D. degree in
Biochemistry in 2001 has opened her road to Europe.
AlthoughshehasbeenaNATOscholarin1996forsix
months in USA as a researcher at the Department of
Physiology and Biophysics at Herb Meiselman’s lab-
oratories (USCL), she wanted to continue her science
career in Europe. From 2001 through 2003, she taught
and researched in Cell Biophysics and Bioengineering
as DAAD Sponsored Guest Professor at the University
of Applied Sciences Aachen, Germany. Due to her
excellent performance and very good feedback from
theirstudentsandcolleagues,shewasacceptedasafull
professor. She successfully integrated her research
interests into the interdisciplinary bioengineering/
biophysics research team, which she joined, in partic-
ular in the development of the CellDrum technology,
but also in different medical applications. E-mail:
A. [email protected]