E & F VOLUTION UTURE OF B IOCONTROL William C. Dunham Managing Partner DunhamTrimmer LLC 20 October 2015 1 Overview • Introduction • Market Drivers • Definitions • Micro Drivers • Historical Development • Multinationals • Bio Companies • Consolidaton • Market Development • The Unexpected • Bio Products • Market Growth • Macro Drivers • Closing 20 October 2015 2 Introduction 2011—Co-Founded DunhamTrimmer LLC • Premier Biological Industries Market Research Firm • Clients: Multinational CPC; Bio Companies; Investors; NGO’s • Due Diligence, Multi-client market data, Single client studies 2013—Launched 2BMonthly • The Global Biocontrol & Biostimulant E-Newsletter • Joint effort New Ag Int’l & DunhamTrimmer • Subscribers: Companies, individuals interested in biological industries 20 October 2015 3 BIOLOGICAL MARKET OVERVIEW --INTRODUCTION—PRODUCT TYPES Biological Products Biofertilizers BioStimulants Biological Control Products Microbials Abiotic Stress Mgmt BioPesticides Macroorganisms N P2O5 Amino Plant Biochemicals Microbials Insects Mites Nema- Fixing Solubiliz Acids Microbials Extracts todes ing MobKili zers Others OArgcaidnsic SEexatwraecetsd Scehmemio- ExPtlraanctt s Minerals PGRs OArgcaidnsic Bacteria Fungi Protozoa Virus OYethaestrss Biofertilizers Biostimulants BioPesticides Macroorganisms • Mtoi ecrnohbainalcse u psleadn t • Sseegamweenedt i Enx tthraisc gtsr omuapke up the largest • Bmsyioinnpteheresattliiscc.i pdBeeiosspt aiecrisedt iedcseid.r eivse tda rfrgoemt s npaetcuifriac lp mesattse arinadls a, rseu cinhh aesr pelnatnlyts l,e bssa ctotexricia t ahnadn certain •• INInnessmeeccatttsso; f dMoellisotewse; d by mites nutrient uptake • Microbials, primarily bacteria, often used makeup the largest from soil • Nitrogen fixing as seed or soil treatment to aid in • gUrnoiuqpuse in that the live bacteria make up nutrient assimilation Biochemicals Microbials organism in the form of largest group • Organic acids are humic and fulvicacids eggs, larvae, pupae or • Others include used as soil amendments, formed by the adult is used. mobilizers of microbial degradation of plant matter. • PPlGaRnst; E Sxetmraicotcsh; Meminicearlasl;s O &r gOatnhiec rs; • BYeaactsetsria; Fungi; Virus; Protozoan; • Most important challenge specific nutrients • Definition and regulation of biostimulants Acids • Bacteria, followed by Fungi make fsohrip Mpiancgr olisv eis olorggaisntiiscms—s (zinc, sulfur) and is still under development in most parts • Plant Extracts make up the largest up the largest groups that have to have special mycorrhizalfungi segment in this group commercially (>90%) of the world care to survive • Biofertilizers • Semiochemicals (pheromones) has • Microbials are the largest market • Normally not classified as regulated under the largest actual number of of biopesticides at US$1.3 Bn. a Biopesticide—only as country/state products • Biggest challenges for microbials Biological Control fertilizer • Largest challenge for Plant Extracts are formulation related: 1) Shelf- Products is manufacturing and consistent life; 2) Stability; 3) Performance regulations quality in the active ingredient(s) enhancement Source: DunhamTrimmer LLC 20 October 2015 4 Stepping Back-Where it all started • 17th Century – Nicotine used to control plum beetles • 1835 – Agostine Bassi demonstrated that white-muscadine fungus (Beauveria bassiana) could be used to cause an infectious disease in silkworm • 19th Century – mineral oils as plant protectants • 1901 – Bt was isolated from a diseased silkworm by Japanese biologist Shigetane Ishiwata • 1911 – Ernst Berliner in Thuringen, Germany, rediscovered Bt – classified as type species Bacillus thuringiensis • Early 1920 s – French growers began to use Bt as a biological insecticide • 1938 – first commercially available Bt product, Sporeine, appeared in France • 1950’s – In USA, widespread use of biopesticides began to take hold as a host of research on Bt efficacy was published *Sources: BPIA website & Willem Ravenburg’sbook, “A Roadmap to the successful Dev& Commof Microbial Pest Control…” 20 October 2015 5 Stepping Back-Where it all started • 1956 – Pacific Yeast Product Company developed an industrial process known as submerged fermentation, which allowed production of Bt on a large scale • 1973 – Heliothis NPV was granted exemption from tolerance and the first viral insecticide Elcar received a label in 1975 • 1977 – Bacillus thuringiensis var. israelensis (toxic to flies) was discovered • 1979 – U.S. EPA registered the first insect pheromone for use in mass trapping of Japanese beetles • 1983 – the Bt strain tenebrionis (toxic to beetles) was discovered *Sources: BPIA website & Willem Ravenburg’sbook, “A Roadmap to the successful Dev& Commof Microbial Pest Control…” 20 October 2015 6 Biocontrol Companies Today Founding of Biocrontrol Companies Founding Members IBMA 14-9-1995 • Abbott BEFORE 1980 24% • Agrisense • BCP 1980'S 16% • Biobest 1990'S 24% • BioTop • Ciba Bunting 2000-2009 30% • ESA • Koppert 2010-PRESENT 6% • Novo Nordisk 0% 5% 10% 15% 20% 25% 30% 35% • NPP Source: DunhamTrimmer Company Database / IBMA 20 October 2015 7 Global Landscape Global BioControl Market Benchmark Values (USD) $US 100 $US 500 $US 1,500 $US 3,000 Million Million Million Million 1993 1999 2005 2009 2012 2014 2016 2020 $US 250 $US 1,000 $US 2,000 $US 4,000 Million Million Million Million BioControl Market (Bn USD) 5 4 3 2 1 0 1993 1999 2005 2009 2012 2014 2016 2020 Source: BioMarketDatabase DunhamTrimmer LLC 20 October 2015 8 Biocontrol Market Stats 2015 Biocontrol Market 2015 Biopesticide Market Plant Extracts Microorganisms USA/Can Lat Am Pheromones ROW Europe Asia/Pac Macroorganisms 2015 Biopesticide Market BioFungicides BioNematicides BioInsecticides Others BioHerbicides 20 October 2015 9 Biopesticides - Registered Products BIOPESTICIDE REGISTRATIONS Brazil 100 EU 125 USA 420 0 100 200 300 400 500 Biopesticide Registrations 20 October 2015 10
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