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Automated analysis of intracranial aneurysm morphology and dynamics from CTA data PDF

93 Pages·2012·5.91 MB·English
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A u t o m a t e d A n A e n u al r y ys sis Dy m of na M In o t mics fro rpholo racrani m gy al a A C n utom TA d ated Dat A a n a ly s is o f In tra c ra n ia l A n e u ry s m M o rp h o lo g y a n d D y n a m ic s fro m C T A D a ta | A z a d e h F iro u z ia n Azadeh Firouzian Automated Analysis of Intracranial Aneurysm Morphology and Dynamics from CTA Data Azadeh Firouzian Azdeh BW6.indd 1 11-12-12 15:49 Advanced School for Computing and Imaging This work was carried out in the ASCI graduate school. ASCI dissertation series number 267. The research in this book was conducted at the Departments of Radiology and Medical Informatics of the Erasmus Medical Centre Rotterdam, the Netherlands. Additional financial support for publishing this thesis was kindly provided by the Department of Radiology of Erasmus MC Rotterdam, the Erasmus University Rotterdam and the ASCI graduate school. About the cover: A goldfish jumping out of a broken fishbowl, representing a life threatening explosion; Goldfish is an essential item of the Nowruz (Persian New Year) table and symbolizes life in Iranian mythology. It also represents the month Pisces when the sun is leaving it and spring starts. ISBN: 978-94-6169-343-3 © Azadeh Firouzian, 2013 All rights reserved. No part of this thesis may be reproduced by any means including electronic, mechanical, photocopying, or otherwise, without the written permission of the author.  layout and printing by: Optima Grafische Communicatie, Rotterdam, The Netherlands Azdeh BW6.indd 2 11-12-12 15:49 Automated Analysis of Intracranial Aneurysm Morphology and Dynamics from CTA Data Geautomatiseerde analyse van de morfologie en dynamiek van intracraniële aneurysmata uit CTA beelden Thesis to obtain the degree of Doctor from the Erasmus University Rotterdam by command of the rector magnificus Prof.dr. H.G. Schmidt and in accordance with the decision of the Doctorate Board. The public defense shall be held on Friday January 25th 2013 at 9:30 am by Azadeh Firouzian born in Tehran, Iran Azdeh BW6.indd 3 11-12-12 15:49 DoCTorAl CoMMITTee Promotor: Prof. dr. W.J. Niessen Other members: Prof. dr. D.W.J. Dippel Prof. dr. ir. A.F.W. van der Steen Prof. dr. ir. C.H. Slump Copromotor: Dr. ir. r. Manniesing Azdeh BW6.indd 4 11-12-12 15:50 Contents 1. Introduction 11 2. Intracranial aneurysm segmentation in 3D CT angiography: 23 Method and quantitative validation with and without prior noise filtering 3. Quantification of intracranial aneurysm morphodynamics from ECG-gated CT 39 angiography 4. Intracranial aneurysm growth quantification in CTA 55 5. Automated quantification of intracranial aneurysm growth in a longitudinal CT 69 angiography study 6. Summary 85 Samenvatting 91 Publications 95 Acknowledgements 97 PhD portfolio 101 About the Author 103 Azdeh BW6.indd 5 11-12-12 15:50 Azdeh BW6.indd 6 11-12-12 15:50 :     و  و ووو و To: My dear pare nts and My little sister To : My dear parents and My little sister Azdeh BW6.indd 7 11-12-12 15:50 Azdeh BW6.indd 8 11-12-12 15:50

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Intracranial aneurysm segmentation in 3D CT angiography: . filtering or nonlinear diffusion using either the regularized Perona & Malik equation or edge .. the edges and constructed from eigenvectors framework which is a standard forward Euler discretization scheme for the numerical approxi-.
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